Hormone Health Hub: Expert Insights on Testing, Balance & Better Living — menopause and hormone resilience

The Women’s Health Initiative (WHI) trial cast a long shadow over hormone replacement therapy — but it enrolled women well over a decade past menopause. Two newer trials, ELITE and KEEPS, specifically studied HRT started early in the postmenopausal period. Their findings on cardiovascular health, sexual function, sleep, mood and cognition paint a more nuanced and encouraging picture. Here is what the latest research shows.

Menopause affects approximately 40–50 million women in the US alone — yet it remains widely misunderstood. This article answers the five essential questions: who is affected, what menopause actually is, when it typically begins, where in the body it originates, and why hormone balance is the key to navigating this natural transition with health and vitality.

When sex hormone test results show both oestradiol (E2) and progesterone (Pg) within normal ranges, yet symptoms persist, the Pg/E2 ratio provides a critical additional layer of clinical insight. A low ratio points to oestrogen dominance; a high ratio to progesterone dominance — each requiring a different therapeutic response. This article explains how the ratio is calculated, when it is clinically relevant, and how a real-world case illustrates its practical value.