Male Saliva Hormone Profile II ( LCMS)

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Test ID: S-140
Sample Type: Saliva
Technology: LC-MS/MS Advanced Laboratory Saliva Hormone Analysis
Results Time: 3–5 Working Days After Laboratory Receives Sample
Laboratory: ZRT Laboratory – CLIA Certified
Hormone Specialist Doctor Interpretation: Included

Suitable For: Adults and Children

The Male Saliva Hormone Profile II (LC-MS/MS) is a comprehensive, non-invasive test that measures seven key male hormones from a simple saliva sample. Designed to assess hormonal balance, energy levels, mood, stress response, and reproductive health, it helps identify imbalances that affect performance and well-being.


What the Test Measures

  • Testosterone (T): The main male hormone responsible for libido, muscle mass, energy, and vitality.
  • Oestradiol (E2): A form of oestrogen that supports mood, bone health, and cardiovascular function.
  • Progesterone (Pg): Supports brain function, libido, and overall hormonal stability.
  • Morning Cortisol: Evaluates stress response and daily energy balance.
  • Noon Cortisol: Measures mid-day stress response and energy maintenance.
  • Evening Cortisol: Assesses how well your body winds down and prepares for rest.
  • Night Cortisol: Assesses the body's ability to rest, recover, and manage stress before sleep.
  • How and when to collect your saliva samples: Saliva Testing Instructions
  • Click to see >> Sample Saliva Test Result Report

Key Features and Benefits

  • Full Hormone Profile: Tests seven essential hormones for a complete hormonal overview.
  • Accurate and Reliable: Lab-certified testing for clinically precise results.
  • At-Home Collection: Simple saliva sampling without needles or clinic visits.
  • Fast Results: Receive your report within 3–5 working days of sample arrival.
  • Expert Review: Includes detailed comments and guidance from a PhD Hormone Specialist.
  • Track Hormonal Changes: Ideal for monitoring testosterone decline, stress patterns, and overtraining effects.
  • Personalised Recommendations: Actionable steps to restore hormone balance and boost energy, mood, and performance.
  • All-Inclusive Kit: Price includes lab fees and analysis; only sample postage required.
  • Long Validity: Use within 12 months of purchase for flexible testing.

Why Saliva Testing?

  • Non-invasive and painless — no blood draw needed.
  • Measures active (bioavailable) hormones that directly affect the body.
  • Easy home collection ensures accurate timing for cortisol and testosterone testing.
  • Perfect for monitoring hormone replacement therapy (HRT), stress, or ageing effects.

Who Should Take This Test

Men who experience:

  • Fatigue or low motivation
  • Reduced libido or erectile issues
  • Mood swings or irritability
  • Sleep disturbances or night sweats
  • Muscle loss or increased abdominal fat
  • Stress, burnout, or recovery problems

How It Works

  1. Order your kit online.
  2. Collect your saliva sample at home following the step-by-step guide.
  3. Send your sample to our accredited laboratory.
  4. Receive detailed results with expert interpretation in 3–5 working days.

FAQ — Male Saliva Hormone Profile II (LC-MS/MS)

1. What hormones does this test measure?
Seven key hormones: testosterone, oestradiol, progesterone, and cortisol (morning, noon, evening, and night).

2. Who should take this test?
Men with low energy, reduced libido, mood changes, poor sleep, or signs of hormonal imbalance.

3. Why use saliva instead of blood?
Saliva measures bioavailable hormones — the active forms influencing your body — using a simple, needle-free method.

4. How do I collect the sample?
Collect saliva at home using the provided tube and instructions. It's fast, hygienic, and pain-free.

5. How long for results?
Within 3–5 working days after the lab receives your sample.

6. What's included in the results?
Graphical and numeric hormone values plus expert commentary and personalised guidance from a Hormone Specialist PhD.

7. Is it suitable for men on hormone therapy?
Yes. The test helps monitor and adjust hormone replacement therapy (HRT) for optimal results.

8. Are there any hidden costs?
No. The price includes all lab fees and analysis; you only cover postage when sending your sample.

9. Can I track changes over time?
Yes. Repeat testing helps monitor testosterone trends, cortisol rhythm, and long-term hormone balance.


What's the Difference Between Each Testing Method?

Enzyme Immunoassay (EIA) — antibody/antigen-based technology with moderate specificity and sensitivity, low cost, not ideal for complex hormone analysis.

Electrochemiluminescence (ECLIA) — improved specificity and sensitivity, commonly used for serum hormone analysis, but not ideal for topical hormone therapies.

Mass Spectrometry (LC-MS/MS) — gold standard for high sensitivity/specificity, extended linear range, and complex hormone analysis.

How to Use

how to collect saliva sample


Why We Partner with ZRT Laboratory

At Hormone Lab UK, every home test kit is analysed by ZRT Laboratory, a globally recognised, CLIA-certified diagnostic and research laboratory specialising in hormone testing, thyroid testing, fertility testing, adrenal function, neurotransmitter analysis, cardiometabolic health, heavy metals, and wellness testing. Founded in 1998 by renowned biochemist and breast cancer researcher Dr. David Zava, PhD, ZRT has become one of the world's leading laboratories for advanced functional health testing.

With more than 11 million laboratory tests performed and healthcare professionals in over 96 countries relying on its expertise, ZRT is recognised for scientific excellence, analytical accuracy, and continuous innovation. Every sample is analysed using state-of-the-art LC-MS/MS and ICP-MS technology under rigorous quality control standards. ZRT collaborates with the CDC, NIH, and leading universities, supporting ongoing research and advances in laboratory medicine.