Female Saliva Hormone Profile I
Are Hormonal Symptoms Occurring Alongside Tiredness or Low Energy?
Are you experiencing menstrual changes, disruptive PMS, hot flushes, reduced libido or persistent tiredness?
This at-home test helps answer one clear question:
How do your core sex hormones, DHEAS and morning cortisol compare with the laboratory’s expected ranges?
Collect one morning saliva sample at the appropriate time in your cycle or treatment schedule. Your ZRT Laboratory report shows five measured hormone levels, compares them with the relevant reference ranges and presents them on clear visual graphs.
The report also includes individualised comments from ZRT’s hormone-specialist clinical team. These comments explain your results in context and, where appropriate, suggest what you could consider or discuss with your healthcare professional next.
£189 — laboratory analysis and specialist laboratory comments included
- One morning saliva sample collected at home
- Five hormone results
- Sex, adrenal androgen and morning cortisol information
- Clear reference-range comparisons
- Visual graph for each measured hormone
- Individualised hormone-specialist laboratory comments
- Suggestions for appropriate next steps
- Physician-reviewed ZRT Laboratory report
- Normally reported within 3–5 working days after the laboratory receives your sample
Is This Test Right for Me?
This test may provide useful additional information if you experience:
- Irregular or changing menstrual cycles
- Premenstrual breast tenderness, bloating or mood changes
- Hot flushes, night sweats or vaginal dryness
- Reduced sexual desire
- Persistent tiredness or low morning energy
- Acne, oily skin or increased facial or body hair
- Sleep difficulties alongside hormonal symptoms
- Symptoms during perimenopause or after menopause
- Hormone-related concerns while using prescribed treatment
This profile is broader than the Essential Female Hormone Saliva Profile because it adds DHEAS and morning cortisol to estradiol, progesterone and testosterone.
The results should be considered alongside your symptoms, menstrual stage, life stage, medicines and hormone treatments.
What Will My Results Help Me Understand?
Your report is designed to show each measured level and help you see which findings may deserve further attention.
1. Review Your Core Sex-Hormone Results
The profile measures estradiol, progesterone and testosterone.
- Estradiol provides information relevant to menstrual and menopausal symptoms.
- Progesterone is interpreted in relation to your cycle stage because it normally rises after ovulation.
- Testosterone provides additional information when reviewing sexual wellbeing or signs of increased androgen activity.
These results help your healthcare professional decide whether further reproductive-hormone testing or clinical assessment may be useful.
2. Understand Your DHEAS Result
DHEAS is produced mainly by the adrenal glands and normally changes with age.
Your report shows your measured level and places it in age-related visual context. This provides additional information about adrenal androgen production.
DHEAS can be converted into other hormones in body tissues, but the result does not directly show your oestrogen or testosterone levels.
3. See Your Morning Cortisol Level
Cortisol naturally changes throughout the day. This profile measures it once, from your morning sample.
Your report shows whether the result falls within the laboratory’s morning range.
This provides a morning cortisol snapshot. It does not show how your cortisol changes from morning to bedtime.
4. Put All Five Results Into Context
Your Test Requisition Form records relevant information about your symptoms, menstrual stage, medicines, supplements and hormone treatments.
ZRT’s hormone-specialist clinical team uses the information provided, where relevant, when preparing the individualised laboratory comments in your report.
This helps you consider the five results together without assuming that one measurement explains all your symptoms.
5. Consider What to Do Next
Your laboratory comments may identify relevant considerations or points to discuss with your healthcare professional.
Depending on your findings and symptoms, this may help you decide whether to:
- Review your results alongside your menstrual and symptom history
- Discuss hot flushes, night sweats or vaginal symptoms
- Consider further reproductive-hormone, thyroid or nutritional testing
- Arrange additional assessment for possible androgen excess or PCOS
- Review prescribed HRT, contraception or other hormone treatment
- Consider a four-point cortisol test if symptoms change throughout the day
- Monitor symptoms and repeat testing after an agreed period
- Discuss any suggested supplement or hormone use before starting treatment
The profile provides additional hormone information to support your next decision. It cannot determine the cause of your symptoms or diagnose a hormonal condition by itself.
What Will My Report Include?
Your physician-reviewed ZRT Laboratory report includes:
- Your salivary estradiol result
- Your salivary progesterone result
- Your salivary testosterone result
- Your DHEAS result
- Your morning cortisol result
- Laboratory reference ranges for comparison
- Clear within-range, high or low result indicators
- Visual graphs showing where each result falls
- Age-related visual context for DHEAS
- Your recorded sample collection date and time
- Your menstrual and life-stage information, where applicable
- Relevant medicines and hormone treatments reported on your form
- Your reported symptoms, where applicable
- Individualised hormone-specialist laboratory comments
- Relevant suggestions or considerations based on the findings
If previous ZRT results are available, they may also appear for comparison, helping you follow changes over time.
What Does the Test Measure?
The test measures five salivary hormones:
- Estradiol (E2)
- Progesterone
- Testosterone
- DHEAS
- Morning cortisol
The profile combines three sex-hormone measurements with DHEAS and one morning cortisol measurement.
Correct cycle timing and complete treatment information are important because the results and relevant reference ranges can vary with menstrual stage, menopause and hormone use.
Test Details
Test ID: S-124
Sample type: Saliva
Hormones measured: Estradiol, progesterone, testosterone, DHEAS and cortisol
Results reported: 5
Testing method: LC-MS/MS
Collection: One morning saliva sample
Laboratory: ZRT Laboratory — CLIA-certified
Specialist interpretation: Individualised hormone-specialist laboratory comments included
Report review: Physician-reviewed
Suitable for: Adults and children
Laboratory reporting time: Normally 3–5 working days after the laboratory receives your sample
What Is Included?
Your purchase includes:
- At-home saliva collection kit
- Saliva collection tube
- Test Requisition Form
- Step-by-step collection and cycle-timing instructions
- Laboratory analysis of five hormones
- Complete ZRT Laboratory results report
- Reference-range comparisons
- Visual result graphs
- Individualised hormone-specialist laboratory comments
- Suggestions or considerations for appropriate next steps
- Physician review of the report
- Laboratory analysis fee
The specialist interpretation is included within your ZRT Laboratory report, so there is no separate interpretation to wait for. Return postage to the laboratory is paid separately by the customer.
How It Works
1. Choose the Appropriate Collection Day
Select your collection day using the cycle-timing guidance supplied with your kit.
Women who do not have menstrual periods can collect on any day, subject to treatment-timing instructions.
2. Collect Your Sample at Home
Collect one saliva sample within 30 minutes of waking, before eating, drinking anything other than water or brushing your teeth.
No blood draw, appointment or clinic visit is required.
3. Send Your Sample to the Laboratory
Label the tube with the collection date and time, complete your Test Requisition Form and post everything to ZRT Laboratory using the packaging and return instructions supplied.
Providing complete information about your symptoms, menstrual history, medicines, supplements and hormone treatments helps the laboratory prepare the most relevant comments.
4. Receive Your Explained Results
ZRT Laboratory analyses your sample and prepares your physician-reviewed report.
The report normally arrives within 3–5 working days after the laboratory receives your sample. It includes your five results, visual comparisons, individualised comments and relevant next-step considerations.
Kit delivery and return-postage time are separate from the laboratory reporting period.
Which Female Hormone Test Should I Choose?
| What do you want to understand? | Recommended test |
|---|---|
| What are my salivary estradiol, progesterone and testosterone levels? | Essential Female Hormone Saliva Profile |
| What are these three sex-hormone levels together with DHEAS and morning cortisol? | Female Saliva Hormone Profile I |
| How do the three core sex hormones relate to cortisol measured across the day? | Female Saliva Hormone Profile II |
| Do I need all three forms of oestrogen together with progesterone, testosterone, DHEAS and morning cortisol? | Female Saliva Hormone Profile III |
Choose this profile if you want the three core sex-hormone measurements together with DHEAS and a morning cortisol result.
Choose a profile with four-point cortisol if your energy, stress or sleep symptoms change noticeably throughout the day.
Preparing for Your Test
Choose Your Collection Day
If you menstruate, use the following schedule:
| Your usual cycle length | When to collect |
|---|---|
| 23–26 days | Day 17, 18 or 19 |
| 27–30 days | Day 21, 22 or 23 |
| 31–34 days | Day 25, 26 or 27 |
| Shorter or longer regular cycles | Five to seven days before your next expected period |
| Infrequent or unpredictable cycles | Any non-bleeding day |
| No menstrual periods | Any day, following treatment-timing instructions where applicable |
Day 1 is the first day of menstrual flow, not spotting.
Prepare and Collect Your Sample
For an accurate and usable sample:
- Collect within 30 minutes of waking.
- Do not eat, drink anything other than water or brush your teeth before collection.
- Avoid anti-ageing or anti-wrinkle facial creams and biotin supplements for three days before testing.
- Record your menstrual stage and all medicines, supplements and hormone treatments on the Test Requisition Form.
- Fill the tube at least halfway, excluding bubbles.
- Freeze the sample if you will not post it within 24 hours.
If you use HRT, hormonal contraception or another hormone treatment, follow the treatment-specific timing instructions supplied with your kit.
Topical hormones can contaminate saliva samples. Use gloves or an applicator, avoid applying hormones to your face, lips or neck and follow all contamination-prevention instructions carefully.
Read the Full Saliva Collection Instructions.
Frequently Asked Questions
Does the Report Explain What My Results Mean?
Yes. Your ZRT Laboratory report includes individualised comments from its hormone-specialist clinical team and is physician-reviewed.
The comments explain your five measured results in context and may include relevant considerations or suggestions about what to discuss with your healthcare professional next.
How Is This Different From the Essential Female Hormone Profile?
The Essential Female Hormone Profile measures estradiol, progesterone and testosterone.
This profile measures those same three hormones and adds DHEAS and morning cortisol. It may be more suitable when hormonal symptoms occur alongside tiredness, low morning energy or stress-related concerns.
Does This Test Show My Complete Daily Cortisol Pattern?
No. It measures cortisol once, from your morning saliva sample.
Choose a four-point cortisol profile if you want to see how cortisol changes from morning to bedtime.
When Should I Collect During My Menstrual Cycle?
The appropriate day depends on your usual cycle length.
For a 27–30-day cycle, collect on day 21, 22 or 23. For other cycle lengths, follow the table above and the instructions supplied with your kit.
Can I Use the Test if I Am Postmenopausal?
Yes. If you no longer have menstrual periods, you can collect on any day, subject to the treatment-timing instructions if you use HRT or another hormone treatment.
Record your menopausal stage and treatments on the Test Requisition Form.
Can I Use the Test While Taking HRT or the Contraceptive Pill?
Yes, subject to the collection and treatment-timing instructions. Continue prescribed treatment unless your prescriber advises otherwise.
Record HRT, contraception and all other treatments on the Test Requisition Form. If you use topical hormones, follow the contamination-prevention instructions carefully.
Can This Test Diagnose Menopause, PCOS or the Cause of PMS?
No. The test provides five salivary hormone measurements for consideration alongside your symptoms and menstrual history.
Diagnosis of menopause, PCOS or another hormonal condition may require clinical assessment and additional investigations.
Why Use Saliva?
Saliva provides a convenient, non-invasive way to collect a morning sample at home. It measures the unbound fraction of the hormones present in the sample.
Blood and saliva tests measure hormones differently and should not be treated as interchangeable.
How Quickly Will I Receive My Results?
The laboratory normally reports within 3–5 working days after receiving your sample. Kit delivery and return-postage times are additional.
How Long Can I Keep the Kit?
Use the kit within 12 months of purchase.
Are There Any Additional Charges?
The collection kit, laboratory analysis and ZRT Laboratory report are included in the price. You are responsible for arranging and paying for return postage to the laboratory.
Not Sure Whether This Is the Right Test?
Email info@hormonelab.co.uk with your age, main symptoms, medicines and current treatments. Our team will forward your enquiry to our specialist doctors and respond with a suggested testing option within 24 hours.
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