Hormone Health Hub: Expert Insights on Testing, Balance & Better Living — Synthetic Estrogens

Estrogen dominance is a common hormone imbalance linked to symptoms such as weight gain, mood swings, heavy periods, fatigue, hot flashes, anxiety, and low libido. Learn the causes of estrogen dominance, how hormone testing works, and natural ways to support hormone balance during reproductive years, perimenopause, and menopause.

Single nucleotide variations (SNVs) in the enzymes that metabolise estrogen can significantly alter breast cancer risk — in some cases by as much as 12-fold when multiple variants combine. In this detailed scientific overview, Jillian Harrington PhD of ZRT Laboratory explains how variations in CYP11A1, CYP19A1 (aromatase), CYP1B1, COMT and MnSOD affect the estrogen metabolism pathway, why catechol estrogens are dangerous, and how methylation testing can reveal individual vulnerability.

Estrogen dominance — an excess of oestrogen relative to progesterone — is one of the most common hormonal imbalances in women. From heavy periods and mood swings to breast tenderness and weight gain, the symptoms are wide-ranging. Discover the causes, what to test, and how to restore balance.