Blog — Estradiol

Topical Delivery of Sex Steroid Hormones and Distribution in Different Body Fluids

Posted by Ben White on

By David Zava, ZRT Laboratory Delivery of the bioidentical hormones estradiol (E2), progesterone (Pg), and testosterone (T) through the skin as a cream or gel (topically) has become a mainstay of bioidentical hormone replacement therapy (BHRT) for women and men. A plethora of FDA-approved pharmaceuticals, compounded, and even over-the-counter topical BHRT products are available. The popularity of these products lies not only in their ease of use but in proven clinical efficacy [1-5] in treating hormonal deficiencies mostly brought on by ageing of the female (menopause) and male (andropause) reproductive systems. Dosing for Optimal Clinical Benefit Over the past 30 or so...

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