Neurotransmitter & Saliva Hormone Test I | Specialist Interpretation Included

Neurotransmitter and Saliva Hormone Test

Test ID: SU-840 (Saliva LCMS Hormones + Dried Urine LCMS Neurotransmitters)

A comprehensive functional assessment combining key sex and adrenal hormones (saliva) with an extensive LCMS urinary neurotransmitter panel. Designed to evaluate hormonal balance, stress physiology, mood regulation, and neurochemical pathways in one integrated profile. This Test combined 7 Saliva Hormone and 26 Dried Urine Neurotransmitters test totaling 33 Tests.

LCMS Dried Urine Neurotransmitters Tests

• Tryptophan (Trp)
• Serotonin (5-HT)
• 5-Hydroxyindoleacetic Acid (5-HIAA)
• Gamma-Aminobutyric Acid (GABA)
• Glycine (Gly)
• Taurine (Tau)
• Glutamate (Glu)
• Glutamine (Gln)
• Histidine (His)
• Histamine (HIST)
• N-Methylhistamine (N-MeHist)
• Phenylethylamine (PEA)
• Tyrosine (Tyr)
• Tyramine (Tyra)
• Dopamine (DA)
• 3,4-Dihydroxyphenylacetic Acid (DOPAC)
• Homovanillic Acid (HVA)
• Norepinephrine (NE)
• Normetanephrine (NMN)
• Epinephrine (Epi)
• Vanillylmandelic Acid (VMA)
• Kynurenine (Kyn)
• Kynurenic Acid (KynAc)
• 3-Hydroxykynurenine (3OHKyn)
• Xanthurenate (Xanth)
• Creatinine (Crtn)

LCMS Saliva Hormone Tests

• Estradiol (E2)
• Estriol (E3)
• Estrone (E1)
• Progesterone (Pg)
• Testosterone (T)
• Dehydroepiandrosterone Sulfate (DS / DHEA-S)
• Cortisol (C)

Why Combine Hormones & Neurotransmitters?

Hormones and neurotransmitters constantly interact.

• Chronic stress alters cortisol and dopamine balance.
• Oestrogen influences serotonin production.
• Progesterone impacts GABA activity.
• DHEA and testosterone affect motivation and mood.

Testing both systems together provides a clearer picture of root causes behind symptoms such as fatigue, anxiety, mood swings, low libido, PMS, insomnia, and burnout.

Why This Test Is Different

LC-MS Gold Standard Technology. Liquid Chromatography–Mass Spectrometry (LCMS) offers:

• High sensitivity & specificity
• Extended linear range
• Reliable detection of complex metabolic pathways

Key Features

• Comprehensive Assessment: Neurotransmitter testing provides a comprehensive evaluation of multiple neurotransmitters, allowing for a more detailed understanding of an individual's neurochemical profile.
• Objective Assessment: Neurotransmitter testing provides an objective measurement of neurotransmitter levels in the body. This can help healthcare providers obtain a more accurate and quantitative understanding of an individual's neurochemical profile, supplementing subjective clinical evaluations.
• Personalised Treatment Approach: By identifying specific neurotransmitter imbalances, testing helps healthcare providers develop personalised treatment strategies tailored to the individual's needs. This can include targeted medication selection, nutrient supplementation, lifestyle modifications, and other interventions to restore balance and optimize neurotransmitter function.
• Diagnostic Aid: Neurotransmitter testing can assist in diagnosing and understanding certain mental health conditions. It can provide objective data that complements clinical assessments, helping clinicians differentiate between different disorders and contributing factors.
• Targeted Interventions: Neurotransmitter testing can help identify specific deficiencies or imbalances that may be contributing to symptoms or health conditions. This information allows for more targeted interventions, focusing on restoring balance and optimizing neurotransmitter function.
• Monitoring Treatment Progress: The testing can be used to monitor the effectiveness of treatment interventions over time. By measuring neurotransmitter levels before and during treatment, healthcare providers can gauge the impact of interventions and make necessary adjustments to optimise outcomes.
• Differential Diagnosis: Neurotransmitter imbalances can manifest in various mental health conditions and neurological disorders. Neurotransmitter testing can aid in the differential diagnosis process, helping healthcare providers differentiate between different conditions and contributing factors.
• Individualised Nutritional Support: Neurotransmitter testing may reveal deficiencies or imbalances that can be addressed through targeted nutrient supplementation.
• Holistic Approach: Neurotransmitter testing promotes a holistic approach to mental health and well-being. It recognises the interplay between neurochemistry, lifestyle factors, and environmental influences, helping to guide treatment decisions beyond pharmaceutical interventions alone.
• Suitability: Neurotransmitters test is suitable for both adults and children.
• Non-invasive at-home sample collection – 4 strips of dried urine collected throughout the day and ease of storage and shipment.
• Accurate, timely, and dependable results.
• Dynamic metabolic pathways are complete with precursors, metabolites, enzymes, and cofactors to guide therapies for optimal neurotransmitter support.
• Personalised, clinical literature-cited report to explain the results and provide treatment considerations.
• Delivery: Free delivery in the UK
• Shipping: Customers are responsible for shipping their samples to the laboratory.
• No Additional Fee: The test kit includes a laboratory fee: no additional laboratory cost or tax.
• How and when to Collect your saliva samples: Saliva Testing Instructions
• Click to see >> Sample Saliva Test Result Report and
• Click to see >> Advanced Neurotransmitter Test Report
• The test must be used within 12 months after the purchase date.
• Test Result Report: You will receive your test result via email within 3–5 working days after the Laboratory receives your sample. On your test result, you will find your hormone levels in graphics and numbers, which makes it easy to understand. You will also find the Laboratory's comments made by Specialist PhD. Dr suggesting how to balance your hormones if there are any imbalanced hormones and what to do next.

The Test Kit pack includes

• Test Requisition Form includes Symptom Checklist
• Requisition Form to complete, including your personal and medical history
• Contains collection instructions
• Cards for collecting a dried urine sample
• Instructions on How to Use Collection Kit
• Return Envelope
• Shipping instruction

NEUROTRANSMITTERS PLAY A KEY ROLE
Neurotransmitters play a key role in facilitating communication between nerve cells (neurons) in the brain and throughout the nervous system. Here are some key roles of neurotransmitters:

• Regulation of Mood and Emotions: Neurotransmitters such as serotonin, dopamine, and norepinephrine are involved in regulating mood, emotions, and feelings of pleasure and reward. Imbalances in these neurotransmitters have been associated with mood disorders like anxiety, depression and bipolar disorder.
• Control of Motor Functions: Neurotransmitters like acetylcholine, dopamine, and gamma-aminobutyric acid (GABA) play a crucial role in controlling and coordinating motor functions. They help regulate muscle movements, balance, and coordination.
• Cognitive Function and Learning: Neurotransmitters like glutamate, acetylcholine, and dopamine contribute to cognitive function, learning, and memory.
• Regulation of Sleep and Wakefulness: Neurotransmitters such as serotonin and norepinephrine help regulate sleep and wakefulness cycles.
• Modulation of Pain Perception: Certain neurotransmitters, such as endorphins and enkephalins, are involved in the modulation of pain perception.
• Autonomic Functions: Neurotransmitters regulate various autonomic functions, including heart rate, blood pressure, digestion, and respiration.
• Regulation of Appetite and Satiety: Neurotransmitters such as serotonin and neuropeptide are involved in the regulation of appetite, satiety, and food intake.

Overall, neurotransmitters play a vital role in numerous physiological and psychological processes, maintaining the proper functioning of the nervous system and influencing various aspects of human behaviour and experience.

ARE YOU AFFECTED?

Imbalances in neurotransmitters can have significant effects on mental and physical health. Here are some potential outcomes of neurotransmitter imbalances:

• Mood Disorders: Alterations in neurotransmitter levels, particularly serotonin, dopamine, and norepinephrine, are associated with mood disorders such as depression, bipolar disorder, and anxiety disorders.
• Cognitive Impairment: Disruptions in neurotransmitter balance can impact cognitive function, memory, attention, and information processing.
• Sleep Disturbances: Imbalances in neurotransmitters can affect the regulation of sleep-wake cycles.
• Neurological Disorders: Neurotransmitter imbalances have been implicated in various neurological conditions.
• Impaired Motor Function: Imbalances in neurotransmitters involved in motor control, such as dopamine, can lead to motor abnormalities.
• Addiction and Substance Abuse: Neurotransmitter imbalances, particularly involving dopamine, play a significant role in addiction and substance abuse.
• Hormonal Imbalances: Neurotransmitters can influence the release and regulation of hormones in the body.
• Digestive Disorders: Neurotransmitter imbalances, such as disruptions in serotonin levels, can impact the digestive system.

Neurotransmitters & Your Health

• Do you suffer from anxiety or depression?

Anxiety and Depression: Imbalances in neurotransmitters such as serotonin, norepinephrine, and dopamine have been associated with anxiety and depression.

• Do you struggle to fall asleep or stay asleep throughout the night?

Sleep Disorders: Neurotransmitters play a role in regulating sleep-wake cycles. Imbalances in neurotransmitters like serotonin and melatonin can disrupt the sleep process.

• Has your libido fizzled?

Libido: Neurotransmitters influence sexual desire and function. Dopamine, in particular, plays a role in the brain's reward and pleasure pathways, including sexual pleasure.

• Women, do you dread the weeks before your period?

Premenstrual Symptoms: Changes in neurotransmitter levels, such as fluctuations in serotonin and gamma-aminobutyric acid (GABA), can contribute to premenstrual symptoms in women.

If you answered yes to these questions, an underlying neurotransmitter imbalance might be the cause. Simple testing may help you find personalised solutions.

Neurotransmitters & Their Impact
Neurotransmitters are chemical messengers used by the nervous system to relay information from one nerve to another. The body relays information through the nervous system about anything that it experiences, hears, touches, smells, or ingests – continuously communicating back and forth between the brain and the body.

Neurotransmitters & Symptoms
Do These Symptoms Sound Familiar?
If you regularly suffer from 3 or more of these symptoms, you might have a neurotransmitter imbalance.

• ADD/ADHD
• Aggression
• Anxiety
• Fatigue
• Forgetfulness
• Hyperactivity
• Impulsive behaviours
• Insomnia
• Low libido
• Mood swings
• Obsessive-compulsive disorder (OCD)
• Panic attacks
• Poor concentration
• Pre-menstrual dysphoric disorder (PMDD)
• Severe PMS
• Sleeping problems

Male Estrogen/Progesterone Deficiency Symptoms:

• Bone loss
• Depression
• Heart palpitations
• Hot flushes
• Neck or back pain
• Night sweats
• Sleeping difficulties

Male Estrogen Dominance/Progesterone Deficiency Symptoms:

• Cold body temperature
• Irritable
• Low libido
• Prostate problems
• Increased urinary urge
• Decreased urine flow
• Breast or hip weight gain

Male low Androgens (DHEA/Testosterone) deficiency symptoms:

• Allergies
• Apathy
• Body temperature cold
• Bone loss
• Burned-out feeling
• Depression
• Decreased erections
• Evening fatigue
• Mental fatigue
• Morning fatigue
• Decreased flexibility
• Forgetfulness
• Headaches
• Heart palpitations
• Hot flushes
• Irritability
• Joint pain
• Low libido
• Decreased mental sharpness
• Decreased muscle size
• Muscle soreness
• Night sweats
• Rapid ageing
• Ringing in ears
• Skin thinning
• Decreased stamina
• Stress
• Triglycerides elevated
• Waist weight gain

Male low Cortisol deficiency symptoms:

• Low blood pressure
• Low blood sugar
• Chemical sensitivity
• Depression
• Dizzy spells
• Fatigue
• Infertility
• Irritability
• Joint pain
• Decreased mental sharpness
• Slow pulse rate
• Decreased stamina
• Stress
• Sugar cravings
• Swelling or puffy eyes/face

Male high Cortisol symptoms:

• Anxious
• High blood pressure
• Depression
• Forgetfulness
• Hot flushes
• Decreased mental sharpness
• Decreased muscle size
• Nervousness
• Night sweats
• Rapid ageing
• Skin thinning
• Sleeping difficulty
• Stress
• Sugar cravings
• Triglycerides elevated
• Waist weight gain

If any symptoms mentioned above persist, you might consider using our comprehensive hormone test. Saliva testing produces a non-invasive result as it does not require the use of any needle or instruments.

Female Estrogen/Progesterone deficiency symptoms:

• Aches & pains
• Acne
• Bone loss
• Depression
• Foggy thinking
• Increased facial or body hair
• Heart palpitations
• Hot flushes
• Incontinence
• Infertility
• Memory lapse
• Night sweats
• Rapid ageing
• Rapid heartbeat
• Skin thinning
• Sleep disturbance
• Tearfulness
• Increased urinary urge
• Vaginal dryness
• Weight gain – waist

Female Estrogen dominance/Progesterone deficiency symptoms:

• Anxious
• Bleeding changes
• Cold body temperature
• Breast cancer
• Fibrocystic breasts
• Tender breasts
• Depression
• Headaches
• Infertility
• Irritability
• Mood swings
• Nervousness
• Uterine fibroids
• Water retention
• Hip weight gain

Female low Androgens (DHEA/Testosterone) deficiency symptoms:

• Aches & pains
• Allergies
• Bone loss
• Depression
• Morning/evening fatigue
• Fibromyalgia
• Headaches
• Incontinence
• Decreased libido
• Memory lapse
• Decreased muscle size
• Rapid ageing
• Skin thinning
• Stamina decreased
• Vaginal dryness

Female high Androgens (DHEA/Testosterone) symptoms:

• Acne
• Breast cancer
• Increased facial or body hair
• Hair-scalp loss
• Irritability
• Triglycerides elevated
• Waist weight gain