Unveiling Hormonal Harmony: A Comprehensive Guide to Female/Male Saliva Profiles I, II & III

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Saliva Hormone Tests

In the intricate tapestry of our body's functions, hormones play a symphony that influences every aspect of our health. ZRT Laboratories offers a suite of convenient saliva profiles – Female/Male Saliva Profiles I, II, and III – designed to unravel the complexities of sex and adrenal hormone levels. In this blog, we'll explore the significance of each profile and the myriad considerations they address for both women and men.

Decoding Saliva Profiles I, II & III:

These three profiles are tailored to provide a snapshot of hormonal levels crucial for understanding overall health, with a focus on sex and adrenal hormones.

Saliva Profile I:

  • Estradiol (E2), Progesterone (Pg), Testosterone (T), DHEA-S (DS), Cortisol (C)
  • A baseline assessment of waking hormone levels is ideal for various health considerations.
Saliva Profile II:
  • Estradiol (E2), Progesterone (Pg), Testosterone (T), DHEA-S (DS), Cortisol (Cx2)
  • Builds upon Profile I with the addition of a bedtime cortisol test, providing insights into hormonal patterns during sleep.
Saliva Profile III:
  • Estradiol (E2), Progesterone (Pg), Testosterone (T), DHEA-S (DS), Cortisol (Cx4)
  • The most comprehensive profile offers a full diurnal cortisol assessment at four-time points throughout the day: morning, noon, evening, and night.

Considerations for Women:

The Saliva Profiles are invaluable tools for women, addressing various health concerns such as:

  • Baseline Levels Before HRT: Ensuring a clear understanding of hormone levels before Hormone Replacement Therapy.
  • Amenorrhea and PMS: Shedding light on irregular menstrual cycles and premenstrual symptoms.
  • Estrogen Dominance Symptoms: Identifying imbalances associated with estrogen dominance.
  • Infertility Screening: Offering insights for women undergoing fertility assessments.
  • Menopausal Symptoms: Assisting in managing symptoms and hormone optimization during menopause.
  • Screening for Adrenal Fatigue: Evaluating adrenal function for those experiencing chronic fatigue.

Considerations for Men:

Men, too, can benefit from these profiles, aiding in the assessment of:

  • Estrogen Dominance: Monitoring hormonal imbalances that may impact overall health.
  • Hypogonadism and Andropause: Offering insights into testosterone levels and age-related hormonal changes.
  • Fatigue and Low Libido: Identifying hormonal factors contributing to energy levels and libido.
  • Osteoporosis Screening: Evaluating bone health through hormone assessments.
  • Adrenal Dysfunction: Assessing adrenal function for those experiencing adrenal-related issues.


The Female/Male Saliva Profiles I, II, and III represent a leap forward in precision health assessment. By delving into waking and bedtime hormone levels and a diurnal cortisol profile, these profiles empower individuals and healthcare professionals with a comprehensive understanding of hormonal dynamics. Whether addressing women's health concerns like amenorrhea or menopausal symptoms or investigating testosterone levels and adrenal function in men, these profiles serve as invaluable tools in the pursuit of hormonal harmony and optimal well-being.

Related Tests

Saliva Hormone Test Section

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