Blog — Sleep Disturbance

Posted by Dr. Allison Smith, ZRT Laboratory. GABA - Gamma-aminobutyric acid, is the neurotransmitter known for its affinity for GABA receptors throughout the central nervous system (CNS). It acts to inhibit excitatory processes – whether they be normal or pathological. It's synthesized from the excitatory neurotransmitter glutamate in a process that requires vitamin B6 as a cofactor. The delicate balance in the brain between GABA and glutamate is orchestrated by shuttle systems from the Krebs Cycle, the presence of NMDA and GABA receptor modulators, enzyme cofactors, and reuptake mediators.   In the rest of the body, GABA plays a myriad of...

60 million American and nearly third of the UK population suffer symptoms of insomnia. Find out whether hormones contribute to your sleep loss. In a perfect world, the master stress hormone cortisol should be in sync with the master sleep hormone melatonin. Each hormone counter-balances the other in a precise rhythm – when cortisol is high melatonin should be low, and when melatonin is high cortisol should be low. For many, this rhythm is out of balance. With an estimated 60 million Americans suffering from some degree of sleep loss and *nearly a third of the UK population are suffering...