Hormone Health Hub: Expert Insights on Testing, Balance & Better Living — Neurotransmitter Imbalance

Dried urine testing is rapidly becoming the preferred method for neurotransmitter and hormone assessment — but collection timing is everything. In this clinical overview, Dr. Kate Placzek of ZRT Laboratory explains why a single morning urine sample cannot substitute for a 4-time-point collection, how neurotransmitters like epinephrine and norepinephrine follow distinct diurnal rhythms, and why interchanging the first and second morning voids can produce grossly inaccurate results.

Neurotransmitter testing is one of the most powerful functional assessment tools available — but it requires a nuanced approach to interpretation. In this clinical overview, Dr. Kate Placzek of ZRT Laboratory outlines the key fundamentals every practitioner needs before reading a neurotransmitter report: from understanding patterns over numbers and treatment sequencing, to the clinical significance of low serotonin on SSRIs, GABA’s peripheral mechanisms, and when to run a diurnal catecholamine assessment.

A growing body of research suggests that mitochondrial dysfunction may lie at the root of many treatment-resistant mental health conditions — including depression, anxiety, bipolar disorder, OCD and even dementia. In this clinical overview, Dr. Peter Bongiorno explains why neurons are particularly vulnerable to mitochondrial damage, how stress, heavy metals and hormonal imbalances compound the problem, and what a comprehensive 5-step repair plan looks like in practice.

What do heavy metals, neurotransmitters and hormone imbalances have in common? In this detailed case study, Dr. Kate Placzek examines Loretta — a 62-year-old postmenopausal woman with breast cancer — and shows how comprehensive testing can reveal the complex biochemical picture behind a cancer diagnosis. A compelling read for anyone interested in the role of hormones and toxic exposure in breast health.

Hot flushes, night sweats, anxiety, insomnia and brain fog — menopause can feel overwhelming. But what is actually happening biochemically? In this case study, Dr. Kate Placzek and Dr. Allison Smith walk through the test results of Julia, a newly postmenopausal woman, showing exactly how hormone and neurotransmitter imbalances drive menopausal symptoms — and what can be done about it.