Blog — Estrogens

By Tracy Tranchitella, ND, ZRT Laboratory The intricate interconnection between the human microbiome and the endocrine system highlights a significant communication network, wherein both systems profoundly influence one another. Particularly noteworthy is the relationship between estrogens and the gut microbiome. The estrobolome is the portion of the microbiome that influences estrogen metabolism. First defined in 2011, the estrobolome is the collection of all enteric bacteria capable of metabolizing estrogens (1). The estrobolome can impact endogenous estrogen metabolism by modulating the enterohepatic circulation of estrogens thus influencing plasma estrogen levels (2). Dysbiosis, diet, and gut infections can alter the microbial environment...

In our current medical paradigm, screening for cancer is considered a preventive measure by virtue of providing an earlier diagnosis. Getting an early jump on a disease process like cancer makes treatment exponentially easier and outcomes generally better. Under the current guidelines, that early jump on prostate cancer starts at age 55 for men at low to moderate risk and 40-45 for men at high risk. It takes years for cancer to grow to a detectable point after the tumor's initial induction from a normal cell to a cancerous one. There's been a lot of research done to determine what...