Hormone Health Hub: Expert Insights on Testing, Balance & Better Living — beta glucuronidase

The human microbiome and the endocrine system are deeply interconnected, engaging in a complex two-way conversation that influences everything from mood to metabolism. One of the most fascinating areas of this interaction centers on estrogen and the gut—a relationship governed by what’s now known as the estrobolome.

The gut microbiome and estrogen are more closely connected than most people realise. As estrogen declines in menopause, microbial diversity falls with it — triggering a cascade of metabolic consequences including weight gain, abdominal fat, inflammation and reduced insulin sensitivity. Dr. Kate Placzek explores the science behind the estrobolome and explains why supporting both gut health and hormone balance is essential for metabolic wellbeing in menopause.