Hormone Health Hub: Expert Insights on Testing, Balance & Better Living — HPA Axis

When we talk about “stress,” or allostatic load, in terms of the perception of an event, we must realize that these “events” must first be translated into neurochemical signals before they trigger the HPA axis. Therefore, the sensitivity and outcome of translating these events (whether they are ongoing events, memories of past events, or stressful anticipation of unrealized events), is highly dependent upon signaling from other neurotransmitters. In fact, the signaling neurotransmitters that manage mood and affect often overlap with measures of HPA axis activation, and cannot be easily distinguished in some subjects. [1] While the detailed influence of neurotransmitters, such...

The latest research confirms what Dr. John Lee and Dr. David Zava argued decades ago: maintaining healthy progesterone levels in proper balance with oestrogen is one of the most powerful tools women have for preventing and recovering from breast cancer. This article outlines seven practical steps to restore hormone balance and reduce breast cancer risk.

The contraceptive pill is one of the most widely used medications in the world — but its effects on mood, brain chemistry and hormone balance are still poorly understood. This article explores how synthetic hormones disrupt oestrogen, progesterone, cortisol and neurotransmitters, and why some women are far more vulnerable to depression and anxiety as a result.

Discover why topical testosterone replacement therapy is frequently over-prescribed and how outdated serum testing methods may fail to reflect true hormone bioavailability. Learn how saliva and dried blood spot testing provide a more accurate picture of tissue hormone delivery, why physiological testosterone dosing matters, and how excessive testosterone may suppress natural production, reduce receptor sensitivity, and impact long-term hormonal balance, energy, mood, libido, and overall men’s health.

 

Hot flashes and night sweats affect up to 80% of women during perimenopause — but they are not inevitable, and they are not forever. The root cause is hormonal imbalance, particularly the out-of-sync fluctuation of oestrogen and progesterone as the ovaries begin to wind down. Discover the lifestyle changes, natural supplements and hormone testing strategies that can bring real relief.