Advanced Neurotransmitter & Toxic Elements Test | 34 Markers

Test ID: U-325 + U-327 | Sample Type: Dried Urine, 4 Timed Collections | Technology: LC-MS and ICP-MS with specialist laboratory interpretation included | Laboratory: ZRT Laboratory (CLIA-certified) | Test Result: Normally 3–5 working days after the laboratory receives your samples | Suitable For: Adults and Children | Collect Sample At Home: No Clinic Visit Required

Neurotransmitters and Toxic Elements — Measured Together in One Dried Urine Test

This combined kit brings together the Advanced 26-marker urinary neurotransmitter profile and a toxic and essential elements panel, using four timed dried urine collections at home.

The two panels provide urinary measurements for discussion with your healthcare practitioner when concerns about mood, sleep, energy or concentration overlap with questions about selected element exposure or intake.

What This Test Measures (34 Markers)

The listed 34-marker total comprises 26 entries in the neurotransmitter profile and eight entries in the elements panel. Creatinine appears in both panels to account for urine concentration, so this does not mean 34 different substances.

Dried Urine — 26 Neurotransmitter-Related Markers (LC-MS)

Dried Urine — Toxic & Essential Elements Panel — 8 Entries (ICP-MS)

Not Sure Which Test Is Right for You?

Email us at info@hormonelab.co.uk with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours with a suggestion.

How This Test Can Help Guide Your Next Steps

If you are struggling with tiredness, brain fog, mood changes or poor sleep, this profile provides additional information about your body’s chemistry to support a more personalised assessment.

Explore pathways related to your symptoms
The test measures urinary markers related to serotonin, dopamine, GABA and other chemical messengers involved in mood, motivation, concentration, relaxation and sleep. Measuring their building blocks and breakdown products gives your healthcare professional a broader picture of how your body processes these substances.

Review relevant nutritional factors
Iodine and selenium measurements provide information about recent intake of nutrients that support normal thyroid function. Your results can guide a discussion about your diet, supplements and whether further nutritional or thyroid testing would be useful.

Investigate possible environmental exposure
The panel measures arsenic, cadmium and mercury in urine. These results can help your healthcare professional assess potential exposure and decide whether to investigate a source, arrange further testing or recommend ways to reduce exposure.

Plan appropriate next steps
Reviewed alongside your symptoms and health history, the findings can help guide further investigations and informed discussions about nutrition, lifestyle and care. They add information to your assessment rather than providing a diagnosis or identifying the cause of symptoms on their own.

How It Works

1. Order your kit — delivered directly to your door
2. Collect four dried urine samples throughout the day using the provided collection strips
3. Post your samples to the laboratory using the provided instructions
4. Receive your results by email within 3–5 working days of the lab receiving your samples

What You Receive With Your Results

• All 34 panel entries in clear graphics and easy-to-read values
• Full neurotransmitter pathway analysis including metabolites and precursors
• Toxic and essential elements panel with reference ranges
• Specialist PhD laboratory interpretation
• Guidance on what your results mean and recommended next steps
• Laboratory analysis for both panels included.

View Sample Neurotransmitter Report | View Sample Toxic Elements Report

Why We Use ZRT Laboratory

All testing is performed by ZRT Laboratory — a globally recognised, CLIA-certified diagnostic laboratory founded in 1998 by Dr. David Zava, PhD. ZRT has performed over 11 million tests and is trusted by healthcare professionals in 96+ countries. ZRT uses both LC-MS and ICP-MS technology to provide clinical-grade accuracy from at-home dried urine samples.

Hormone Lab UK (Testfield UK Ltd) is the official UK test provider for ZRT Laboratory.

Important Information

• Laboratory analysis for both panels is included in the price
• A return envelope is supplied, but it is not prepaid. Customers pay return postage to the laboratory
• Test kit valid for 12 months from purchase date

Dried Urine Sample Collection Instructions

Collect four timed dried urine samples using the supplied materials with your test kit.

Before You Begin

Read sample collection and shipping instructions supplied with your kit. Record all current medications, supplements and hormone treatments on the Test Requisition Form.

Choosing Your Collection Day

• Men and children: Collect on any day of the month.
• Women who do not menstruate, including postmenopausal women: Collect on any day of the month.
• Women with regular periods: Choose a non-bleeding day. This urine-only test does not require collection on a specific day of your menstrual cycle.
• Women with irregular or infrequent periods: Collect on any non-bleeding day.

Avoid collecting during menstruation or whenever blood may be present in your urine. If you use hormone treatments, also follow the guidance below.

When to Collect

All groups should collect samples at the following four times:

Before your first collection, do not eat, drink anything other than water, or take vitamins or supplements. Follow your healthcare provider’s advice about medication timing; do not stop prescribed medication without their advice.

Limit fluid intake to no more than approximately 240 ml (8 oz) during the hour before each collection to avoid diluting your sample.

How to Collect Each Sample

• Remove a collection card from its bag. Write your name, collection date and time on the card before collecting.
• Open the cover and fold it away from the filter paper. Avoid touching the filter paper.
• Fully saturate the filter paper by urinating directly onto it, or collect urine in a clean cup and dip the paper up to the top black dashed line.
• Hang or tape the card somewhere secure to dry. Ensure the wet filter paper does not touch anything.
• Allow the sample to dry completely for at least six hours. Once completely dry, refold the card, place it in its bag and seal it. Do not leave samples outside the bag for longer than 24 hours.
• Repeat these steps for each collection time.

If You Use Hormone Treatments

Record all hormone treatments on your Test Requisition Form. Follow the hormone-use instructions supplied with your kit and your healthcare provider’s advice. Do not stop prescribed hormone treatment without their advice.

• Morning hormones: Take or apply your usual morning dose after the first urine collection. Wash your hands thoroughly afterwards, especially after applying topical hormones.
• Nighttime hormones: Collect your bedtime sample before taking or applying your nighttime dose.
• Vaginal hormones: The laboratory’s instructions advise avoiding vaginal hormone use during the collection day until after the final urine sample. Discuss timing with your healthcare provider if needed.

If You Miss a Collection

Collect the missed sample at the same time the following day. For example, collect a missed evening sample the following evening. Record the actual collection date and time on both the card and the Test Requisition Form, then follow the same drying and sealing instructions.

Returning Your Samples

Complete the Test Requisition Form in full. Place it, any additional paperwork and all sealed, completely dry samples into the test kit box. Pack and return the kit according to the return instructions provided.

A return envelope is provided with your kit. It is not prepaid; customers are responsible for return postage to the laboratory.

Important: Urine samples that are wet, unsealed, excessively diluted or more than 30 days old will not be processed.

Collection Instructions: View dried urine collection instructions

Frequently Asked Questions

How do heavy metals affect neurotransmitters?
Exposure to certain toxic elements can affect nervous-system function. This kit measures selected urinary elements alongside neurotransmitter-related markers, allowing your practitioner to review both sets of results in context. It does not establish that an exposure caused your symptoms or measure the resulting effect on brain neurotransmitters.

Why is iodine included in the elements panel?
Iodine is essential for thyroid hormone production. The panel measures urinary iodine alongside other selected elements, including selenium and bromine. Results should be reviewed with your healthcare practitioner and do not, by themselves, diagnose iodine deficiency or thyroid disease.

Is this test suitable for children?
The dried urine collection method is non-invasive and suitable for adults and children. 

Can this test diagnose heavy metal poisoning or neurological conditions?
No. This test cannot diagnose medical conditions. It provides biochemical data about urinary excretion of neurotransmitters and elements that may help guide further investigation with a qualified healthcare professional.

Does the price include the laboratory fee?
Yes. The full laboratory analysis fee for both panels is included. Return postage to the laboratory is not included.

How long is the kit valid for?
The kit must be used within 12 months of the purchase date.