Male Saliva Hormone Profile I
Concerned About Libido, Energy or Changes in Strength?
Have you noticed reduced sexual desire, fewer morning erections, persistent tiredness, changes in muscle strength or breast tenderness?
This at-home test helps answer one clear question:
How do your salivary testosterone, estradiol, progesterone, DHEAS and morning cortisol levels compare with the laboratory’s expected ranges?
Collect one morning saliva sample at home. Your ZRT Laboratory report shows five measured hormone levels, compares them with the relevant reference ranges and presents them on clear visual graphs.
The report also includes individualised comments from ZRT’s hormone-specialist clinical team. These comments explain your results in context and, where appropriate, suggest what you could consider or discuss with your healthcare professional next.
£189 — laboratory analysis and specialist laboratory comments included
- One morning saliva sample collected at home
- Five hormone results
- Sex-hormone, adrenal androgen and morning cortisol information
- Clear reference-range comparisons
- Visual graph for each measured hormone
- Individualised hormone-specialist laboratory comments
- Suggestions for appropriate next steps
- Physician-reviewed ZRT Laboratory report
- Normally reported within 3–5 working days after the laboratory receives your sample
Is This Test Right for Me?
This profile may provide useful additional information if you experience:
- Reduced sexual desire
- Fewer spontaneous or morning erections
- Erectile difficulties, particularly with reduced libido
- Reduced muscle mass or strength
- Persistent tiredness or low morning energy
- Breast tenderness or enlargement
- Reduced motivation or low mood accompanied by sexual symptoms
- Poor recovery from exercise
- Hormone-related concerns while using prescribed treatment
This profile is broader than the Essential Male Hormone Saliva Profile because it adds DHEAS and morning cortisol to testosterone, estradiol and progesterone.
The results should be considered alongside your symptoms, medicines, treatments and established clinical tests.
What Will My Results Help Me Understand?
Your report is designed to show each measured level and help you see which findings may deserve further attention.
1. Review Your Testosterone and Estradiol Results
Testosterone has established roles in male sexual function, muscle mass, bone health and physical wellbeing.
Men also need estradiol, which contributes to bone health and sexual function. Breast tenderness or enlargement does not automatically mean that estradiol is high.
Your report shows both measured levels and compares them with the relevant laboratory ranges.
These results can help your healthcare professional decide whether appropriately timed blood testosterone, estradiol, SHBG, albumin or other investigations may be useful.
2. Understand Your DHEAS Result
DHEAS is produced mainly by the adrenal glands and normally changes with age.
Your report shows your measured DHEAS level and places it in age-related visual context. This provides additional information about adrenal androgen production.
DHEAS is not testosterone, and a low DHEAS result does not automatically mean that your testosterone level is low.
3. See Your Morning Cortisol Level
Cortisol naturally changes throughout the day. This profile measures it once, from your morning sample.
Your report shows whether the result falls within the laboratory’s morning range.
This provides a morning cortisol snapshot. It does not show your complete daily cortisol pattern or establish whether stress is suppressing testosterone.
4. Put the Progesterone Result Into Context
Progesterone provides an additional sex-hormone measurement within the profile.
Its usefulness for explaining common male symptoms is less established than that of testosterone. The result should therefore be considered alongside the other measurements, your symptoms, medicines and treatment history.
It should not be treated as proof of “oestrogen dominance” or as the hidden cause of low libido, erectile difficulties or reduced muscle development.
5. Consider What to Do Next
Your laboratory comments explain the measured results and may identify relevant points to discuss with your healthcare professional.
Depending on your results and symptoms, this may help you decide whether to:
- Arrange morning blood testosterone testing
- Assess SHBG and albumin so calculated free testosterone can be considered
- Discuss breast tenderness or enlargement with a healthcare professional
- Review medicines or treatments that may affect hormone levels
- Investigate other possible causes of tiredness, low mood or erectile difficulties
- Consider a four-point cortisol test if symptoms change throughout the day
- Monitor symptoms and repeat testing after an agreed period
- Discuss any suggested supplement or hormone use before starting treatment
The profile provides additional hormone information to support your next decision. It cannot diagnose testosterone deficiency, adrenal dysfunction or the cause of your symptoms by itself.
What Will My Report Include?
Your physician-reviewed ZRT Laboratory report includes:
- Your salivary testosterone result
- Your salivary estradiol result
- Your salivary progesterone result
- Your DHEAS result
- Your morning cortisol result
- Laboratory reference ranges for comparison
- Clear within-range, high or low result indicators
- Visual graphs showing where each result falls
- Age-related visual context for DHEAS
- Your recorded sample collection date and time
- Relevant medicines and hormone treatments reported on your form
- Your reported symptoms, where applicable
- Individualised hormone-specialist laboratory comments
- Relevant suggestions or considerations based on the findings
If previous ZRT results are available, they may also appear for comparison, helping you follow changes over time.
What Does the Test Measure?
The test measures five salivary hormones:
- Testosterone
- Estradiol (E2)
- Progesterone
- DHEAS
- Morning cortisol
The profile combines three sex-hormone measurements with DHEAS and one morning cortisol measurement.
Saliva and blood tests measure hormones differently. This profile provides additional salivary measurements and does not replace the blood investigations commonly used to diagnose testosterone deficiency or monitor TRT.
Test Details
Test ID: S-124
Sample type: Saliva
Hormones measured: Testosterone, estradiol, progesterone, DHEAS and cortisol
Results reported: 5
Testing method: LC-MS/MS
Collection: One morning saliva sample
Laboratory: ZRT Laboratory — CLIA-certified
Specialist interpretation: Individualised hormone-specialist laboratory comments included
Report review: Physician-reviewed
Suitable for: Adults and children
Laboratory reporting time: Normally 3–5 working days after the laboratory receives your sample
What Is Included?
Your purchase includes:
- At-home saliva collection kit
- Saliva collection tube
- Test Requisition Form
- Step-by-step collection instructions
- Laboratory analysis of five hormones
- Complete ZRT Laboratory results report
- Reference-range comparisons
- Visual result graphs
- Individualised hormone-specialist laboratory comments
- Suggestions or considerations for appropriate next steps
- Physician review of the report
- Laboratory analysis fee
The specialist interpretation is included within your ZRT Laboratory report, so there is no separate interpretation to wait for. Return postage to the laboratory is paid separately by the customer.
How It Works
1. Collect Your Sample at Home
Collect one saliva sample within 30 minutes of waking, before eating, drinking anything other than water or brushing your teeth.
No blood draw, appointment or clinic visit is required.
2. Send Your Sample to the Laboratory
Label the tube with the collection date and time, complete your Test Requisition Form and post everything to ZRT Laboratory using the packaging and return instructions supplied.
Providing complete information about your symptoms, medicines, supplements and hormone treatments helps the laboratory prepare the most relevant comments.
3. Receive Your Explained Results
ZRT Laboratory analyses your sample and prepares your physician-reviewed report.
The report normally arrives within 3–5 working days after the laboratory receives your sample. It includes your five hormone results, visual comparisons, individualised comments and relevant next-step considerations.
Kit delivery and return-postage time are separate from the laboratory reporting period.
Which Male Hormone Test Should I Choose?
| What do you want to understand? | Recommended test |
|---|---|
| What are my salivary testosterone, estradiol and progesterone levels? | Essential Male Hormone Saliva Profile |
| What are these three sex-hormone levels together with DHEAS and morning cortisol? | Male Saliva Hormone Profile I |
| How does my cortisol change from morning to bedtime? | Male All Day Cortisol Test |
| How does my cortisol change across the day, and what is my DHEAS level? | Male Adrenal Function Saliva Test Kit |
Choose this profile if you want the three core sex-hormone measurements together with DHEAS and a morning cortisol result.
Choose a four-point cortisol test if your tiredness, energy, stress or sleep symptoms change noticeably throughout the day.
Preparing for Your Test
For an accurate and usable sample:
- Collect within 30 minutes of waking.
- Do not eat, drink anything other than water or brush your teeth before collection.
- Avoid anti-ageing or anti-wrinkle facial creams and biotin supplements for three days before testing.
- Record all medicines, supplements and hormone treatments on the Test Requisition Form.
- Fill the tube at least halfway, excluding bubbles.
- Freeze the sample if you will not post it within 24 hours.
If you use TRT or another hormone treatment, follow the treatment-specific timing instructions supplied with your kit.
Topical hormones can contaminate saliva samples. Use gloves or an applicator, avoid applying hormones to your face, lips or neck and follow all contamination-prevention instructions carefully.
Read the Full Saliva Collection Instructions.
Frequently Asked Questions
Does the Report Explain What My Results Mean?
Yes. Your ZRT Laboratory report includes individualised comments from its hormone-specialist clinical team and is physician-reviewed.
The comments explain your five measured results in context and may include relevant considerations or suggestions about what to discuss with your healthcare professional next.
How Is This Different From the Essential Male Hormone Profile?
The Essential Male Hormone Profile measures testosterone, estradiol and progesterone.
This profile measures those same three hormones and adds DHEAS and morning cortisol. It may be more suitable when sexual or physical symptoms occur alongside tiredness, low morning energy or stress-related concerns.
Can This Test Diagnose Low Testosterone?
No. It provides a salivary testosterone measurement for additional information.
Diagnosis of testosterone deficiency usually requires relevant symptoms together with appropriately timed blood testosterone measurements. SHBG, albumin, luteinising hormone and other markers may also be needed.
Does the Test Calculate Hormone Ratios?
The report presents the individual hormone measurements, reference ranges, graphs and laboratory comments.
Do not assume that testosterone-to-estradiol, cortisol-to-testosterone or progesterone-to-estradiol ratios will be calculated unless they appear explicitly in the laboratory report.
Is This Test Useful if I Am Concerned About Overtraining?
The profile provides one morning testosterone result and one morning cortisol result. These measurements can be considered alongside your training, recovery, sleep and symptoms.
A single morning sample cannot establish overtraining or show your full daily cortisol pattern. A four-point cortisol profile may provide more information if symptoms change throughout the day.
Can I Use This Test While on TRT?
Yes, subject to the collection and treatment-timing instructions. Continue prescribed treatment and record TRT and all other medicines on the Test Requisition Form.
This saliva profile may provide additional hormone measurements, but it does not replace the blood tests and clinical monitoring used to assess TRT safety or effectiveness.
Does This Test Show My Complete Daily Cortisol Pattern?
No. It measures cortisol once, from your morning saliva sample.
Choose a four-point cortisol profile if you want to see how cortisol changes from morning to bedtime.
Why Use Saliva?
Saliva provides a convenient, non-invasive way to collect a morning sample at home. It measures the unbound fraction of the hormones present in the sample.
Blood and saliva tests measure hormones differently and should not be treated as interchangeable.
How Quickly Will I Receive My Results?
The laboratory normally reports within 3–5 working days after receiving your sample. Kit delivery and return-postage times are additional.
How Long Can I Keep the Kit?
Use the kit within 12 months of purchase.
Are There Any Additional Charges?
The collection kit, laboratory analysis and ZRT Laboratory report are included in the price. You are responsible for arranging and paying for return postage to the laboratory.
Not Sure Whether This Is the Right Test?
Email info@hormonelab.co.uk with your age, main symptoms, medicines and current treatments. Our team will forward your enquiry to our specialist doctors and respond with a suggested testing option within 24 hours.
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