Hormone Health Hub: Expert Insights on Testing, Balance & Better Living — neurotransmitters and mood

Dried urine testing is rapidly becoming the preferred method for neurotransmitter and hormone assessment — but collection timing is everything. In this clinical overview, Dr. Kate Placzek of ZRT Laboratory explains why a single morning urine sample cannot substitute for a 4-time-point collection, how neurotransmitters like epinephrine and norepinephrine follow distinct diurnal rhythms, and why interchanging the first and second morning voids can produce grossly inaccurate results.

As the days shorten and sunlight fades, four key hormonal systems come under pressure: vitamin D, serotonin, cortisol and melatonin. For those susceptible to Seasonal Affective Disorder (SAD), the disruption of these interconnected rhythms can trigger depression, fatigue, poor sleep and low mood. This article explains the science behind the SAD hormone pattern — and what you can do to support your body through the darker months.