{"product_id":"male-comprehensive-hormone-profile-ii-blood-spot","title":"Male Comprehensive Hormone Profile II","description":"\u003ch1\u003eMale Comprehensive Hormone Profile II – 14-Marker Blood Spot Test (Hormones + Full Thyroid Panel)\u003c\/h1\u003e\n\u003cp\u003e\u003cstrong\u003eTest ID: B-243M\u003c\/strong\u003e | At-Home Blood Spot Collection | Results in 3–5 Working Days | Designed for Men\u003c\/p\u003e\n\n\u003cp\u003eThe \u003cstrong\u003eMale Comprehensive Hormone Profile II\u003c\/strong\u003e is our most advanced men’s hormone blood spot test, measuring \u003cstrong\u003e14 essential markers\u003c\/strong\u003e across sex hormones, adrenal function, and a complete thyroid panel. Using highly accurate \u003cstrong\u003eLC-MS\/MS technology\u003c\/strong\u003e through our CLIA-certified partner, \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e, this test is ideal for men experiencing complex hormonal symptoms, andropause, thyroid dysfunction, chronic fatigue, or unexplained changes in body composition, mood, or performance.\u003c\/p\u003e\n\n\u003ch2\u003eWhat Does This Test Measure?\u003c\/h2\u003e\n\n\u003ch3\u003eSex Hormones (8 Markers)\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eEstrone (E1)\u003c\/strong\u003e – an oestrogen present in men; elevated levels are linked to fat gain and hormonal imbalance\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEstradiol (E2)\u003c\/strong\u003e – the primary oestrogen; men need balanced E2 for bone density and cardiovascular health, but excess causes low libido and gynaecomastia\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEstriol (E3)\u003c\/strong\u003e – a weaker oestrogen that helps assess overall oestrogen load in men\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProgesterone (Pg)\u003c\/strong\u003e – supports testosterone production and counteracts oestrogen dominance in men\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTestosterone (T)\u003c\/strong\u003e – the primary male sex hormone; critical for energy, muscle mass, libido, mood, and metabolic health\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDHEA-S (DS)\u003c\/strong\u003e – an adrenal precursor hormone that declines with age; linked to vitality, immune function, and testosterone production\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCortisol (C)\u003c\/strong\u003e – the stress hormone; chronically elevated cortisol directly suppresses testosterone\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSex Hormone Binding Globulin (SHBG)\u003c\/strong\u003e – regulates how much testosterone is biologically available; high SHBG causes low-T symptoms even when total testosterone appears normal\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eFull Thyroid Panel (6 Markers)\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eThyroid Stimulating Hormone (TSH)\u003c\/strong\u003e – the primary screening marker for thyroid function\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFree Triiodothyronine (fT3)\u003c\/strong\u003e – the active thyroid hormone; low fT3 is linked to fatigue, weight gain, and depression\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFree Thyroxine (fT4)\u003c\/strong\u003e – the storage thyroid hormone converted to fT3; key for assessing conversion issues\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThyroid Peroxidase Antibody (TPOab)\u003c\/strong\u003e – elevated levels indicate autoimmune thyroid disease (Hashimoto’s)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThyroglobulin (Tgbn)\u003c\/strong\u003e – a marker for thyroid tissue health and autoimmune activity\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTotal Thyroxine (TT4)\u003c\/strong\u003e – measures total thyroxine including protein-bound hormone\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWho Is This Test For?\u003c\/h2\u003e\n\u003cp\u003eThis test is ideal for men experiencing complex or overlapping symptoms that may involve both hormonal and thyroid imbalance, including:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePersistent fatigue, morning or evening exhaustion\u003c\/li\u003e\n\u003cli\u003eLow libido or erectile dysfunction\u003c\/li\u003e\n\u003cli\u003eLoss of muscle mass or increased body fat\u003c\/li\u003e\n\u003cli\u003eMood swings, depression, or anxiety\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor concentration, or increased forgetfulness\u003c\/li\u003e\n\u003cli\u003eSleep disturbances or insomnia\u003c\/li\u003e\n\u003cli\u003eHot flashes or night sweats (andropause symptoms)\u003c\/li\u003e\n\u003cli\u003eUnexplained weight gain or slow metabolism\u003c\/li\u003e\n\u003cli\u003eHair thinning or loss\u003c\/li\u003e\n\u003cli\u003eDecreased stamina or physical performance\u003c\/li\u003e\n\u003cli\u003eHigh cholesterol or elevated triglycerides\u003c\/li\u003e\n\u003cli\u003eHeart palpitations or rapid heartbeat\u003c\/li\u003e\n\u003cli\u003eCold intolerance or low body temperature\u003c\/li\u003e\n\u003cli\u003eBone loss or decreased muscle size\u003c\/li\u003e\n\u003cli\u003eFertility concerns\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy Test Hormones and Thyroid Together?\u003c\/h2\u003e\n\u003cp\u003eThyroid and sex hormones are deeply interconnected in men. Thyroid dysfunction can suppress testosterone, raise SHBG, and worsen symptoms of andropause — and vice versa. Many men are treated for low testosterone when the root cause is actually thyroid dysfunction. Testing both systems together gives you and your doctor a complete clinical picture, avoiding misdiagnosis and enabling more targeted treatment.\u003c\/p\u003e\n\n\u003ch2\u003eUnderstanding Your Key Hormone Systems\u003c\/h2\u003e\n\n\u003ch3\u003eTestosterone, Oestrogen \u0026amp; SHBG\u003c\/h3\u003e\n\u003cp\u003eTestosterone is the cornerstone of male hormonal health — essential for energy, muscle mass, libido, bone density, and psychological wellbeing. As men age, testosterone declines while oestrogen (produced by conversion of testosterone via aromatase) can rise. High oestrogen in men is linked to gynaecomastia, fat gain, low libido, and mood issues. SHBG regulates how much testosterone is free and active — high SHBG is a common and frequently overlooked cause of low-testosterone symptoms.\u003c\/p\u003e\n\n\u003ch3\u003eDHEA-S \u0026amp; Adrenal Function\u003c\/h3\u003e\n\u003cp\u003eDHEA-S is produced by the adrenal glands and is a key precursor to testosterone and other androgens. It peaks in early adulthood and declines steadily with age. Low DHEA-S is associated with fatigue, low mood, reduced immunity, and declining testosterone. It is an important marker of adrenal reserve and overall hormonal vitality in men.\u003c\/p\u003e\n\n\u003ch3\u003eCortisol \u0026amp; Stress Response\u003c\/h3\u003e\n\u003cp\u003eCortisol follows a daily rhythm — highest in the morning, lowest at night. Chronically elevated cortisol, driven by prolonged stress, directly suppresses testosterone production and disrupts the entire hormonal cascade. Long-term cortisol imbalance is linked to metabolic dysfunction, osteoporosis, cardiovascular disease, and cognitive decline.\u003c\/p\u003e\n\n\u003ch3\u003eThyroid Function\u003c\/h3\u003e\n\u003cp\u003eThyroid hormones regulate metabolism, energy, temperature, and mood in men. Hypothyroidism is often underdiagnosed in men because symptoms overlap with low testosterone and andropause. This panel includes fT3, fT4, TPO antibodies, thyroglobulin, and TT4 — giving a complete picture of thyroid function and autoimmune activity (Hashimoto’s thyroiditis), which affects men as well as women.\u003c\/p\u003e\n\n\u003ch2\u003eHow Does the Test Work?\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrder your kit\u003c\/strong\u003e – delivered directly to your door across the UK\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCollect your sample at home\u003c\/strong\u003e – a simple finger-prick blood spot collection, no clinic visit required\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePost your sample\u003c\/strong\u003e – send it to our ZRT Laboratory using standard post (shipping cost is your responsibility)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReceive your results\u003c\/strong\u003e – within 3–5 working days of the lab receiving your sample\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReview your report\u003c\/strong\u003e – detailed hormone level graphics, numerical values, and specialist commentary from a PhD Hormone Specialist Doctor\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003e👉 \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/female-blood-profile-ii_ecc60223-655c-4777-9af7-cf5ab714c00c.pdf?v=1702910693\"\u003e\u003cstrong\u003eView a Sample Test Result Report\u003c\/strong\u003e\u003c\/a\u003e\u003c\/em\u003e\u003c\/p\u003e\n\n\u003ch2\u003eWhat’s Included in the Kit?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eBlood spot collection card\u003c\/li\u003e\n\u003cli\u003eLancets for finger-prick sampling\u003c\/li\u003e\n\u003cli\u003eFull step-by-step instructions\u003c\/li\u003e\n\u003cli\u003eLaboratory fee (no additional lab costs or hidden charges)\u003c\/li\u003e\n\u003cli\u003eValid for 12 months from purchase date\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePioneers of at-home dried blood spot (DBS) hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e and \u003cstrong\u003eICP-MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e for testosterone and estradiol\u003c\/li\u003e\n\u003cli\u003ePersonalised reference ranges based on age and sex\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThrough our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to men across the UK and Europe — from the comfort of home.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":58590121132413,"sku":"751","price":270.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Insulin_Test_Kit.png?v=1787500073","url":"https:\/\/hormonelab.co.uk\/products\/male-comprehensive-hormone-profile-ii-blood-spot","provider":"Hormone Lab UK","version":"1.0","type":"link"}