{"product_id":"advanced-neurotransmitter-hormone-test-i","title":"Advanced Neurotransmitter \u0026 Hormone Test I | Specialist Interpretation Included","description":"\u003cp\u003e\u003cstrong\u003e\u003cmeta charset=\"utf-8\"\u003e\n\u003cspan style=\"text-decoration: underline;\"\u003eTest ID: \u003cmeta charset=\"utf-8\"\u003eSU-841 \u003c\/span\u003eAdvanced \u003cmeta charset=\"utf-8\"\u003eNeurotransmitter \u0026amp; Hormone  Test (\u003cmeta charset=\"utf-8\"\u003eSaliva LCMS Hormones 7 + Dried Urine LCMS Neurotransmitters and Diurnal Hormones I) \u003cmeta charset=\"utf-8\"\u003e \u003cspan\u003e|  \u003c\/span\u003eSample Type:\u003cspan\u003e Dried Urine \u0026amp; Saliva  |  \u003c\/span\u003eTechnology:\u003cspan\u003e Advanced LCMS analysis with specialist laboratory interpretation included.\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis is an advanced functional assessment designed to evaluate the dynamic relationship between hormones and brain chemistry. This comprehensive profile measures 7 key sex and adrenal hormones in saliva using LCMS technology, alongside 42 dried urine neurotransmitters and diurnal hormone markers — delivering \u003cstrong\u003ea total of 49 clinically relevant markers\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003eBy integrating endocrine and neurotransmitter analysis, this test provides a detailed overview of hormonal balance, adrenal rhythm, stress response, mood regulation, and neurochemical pathways. It helps identify imbalances associated with anxiety, depression, ADHD, fatigue, sleep disturbances, and chronic stress.\u003c\/p\u003e\n\u003cp\u003eThe inclusion of diurnal cortisol and cortisone patterns offers deeper insight into daily adrenal function and stress physiology, delivering a data-driven and clinically meaningful neuroendocrine evaluation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLCMS Saliva Hormone Tests\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eEstradiol (E2)\u003c\/li\u003e\n\u003cli\u003eEstriol (E3)\u003c\/li\u003e\n\u003cli\u003eEstrone (E1)\u003c\/li\u003e\n\u003cli\u003eProgesterone (Pg)\u003c\/li\u003e\n\u003cli\u003eTestosterone (T)\u003c\/li\u003e\n\u003cli\u003eDehydroepiandrosterone Sulfate (DS)\u003c\/li\u003e\n\u003cli\u003eCortisol (C)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eLCMS Dried Urine Neurotransmitters Tests\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTryptophan (Trp)\u003c\/li\u003e\n\u003cli\u003eSerotonin (5-HT)\u003c\/li\u003e\n\u003cli\u003e5-Hydroxyindoleacetic Acid (5-HIAA)\u003c\/li\u003e\n\u003cli\u003eGamma-Aminobutyric Acid (GABA)\u003c\/li\u003e\n\u003cli\u003eGlycine (Gly)\u003c\/li\u003e\n\u003cli\u003eTaurine (Tau)\u003c\/li\u003e\n\u003cli\u003eGlutamate (Glu)\u003c\/li\u003e\n\u003cli\u003eGlutamine (Gln)\u003c\/li\u003e\n\u003cli\u003eHistidine (His)\u003c\/li\u003e\n\u003cli\u003eHistamine (HIST)\u003c\/li\u003e\n\u003cli\u003eN-Methylhistamine (N-MeHist)\u003c\/li\u003e\n\u003cli\u003ePhenylethylamine (PEA)\u003c\/li\u003e\n\u003cli\u003eTyrosine (Tyr)\u003c\/li\u003e\n\u003cli\u003eTyramine (Tyra)\u003c\/li\u003e\n\u003cli\u003eDopamine (DA)\u003c\/li\u003e\n\u003cli\u003eDihydroxyphenylacetic Acid (DOPAC)\u003c\/li\u003e\n\u003cli\u003eHomovanillic Acid (HVA)\u003c\/li\u003e\n\u003cli\u003eNorepinephrine (NE)\u003c\/li\u003e\n\u003cli\u003eNormetanephrine (NMN)\u003c\/li\u003e\n\u003cli\u003eEpinephrine (Epi)\u003c\/li\u003e\n\u003cli\u003eVanillylmandelic Acid (VMA)\u003c\/li\u003e\n\u003cli\u003eKynurenine (Kyn)\u003c\/li\u003e\n\u003cli\u003eKynurenic Acid (KynAc)\u003c\/li\u003e\n\u003cli\u003e3-Hydroxykynurenine (3OHKyn)\u003c\/li\u003e\n\u003cli\u003eXanthurenate (Xanth)\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eCreatinine (Crtn) ×5\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eFree Cortisol (FC) ×4\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eFree Cortisone (FCn) ×4\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003e6-Sulfatoxymelatonin (MT6s) ×4\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy Combine Hormones \u0026amp; Neurotransmitters?\u003c\/h2\u003e\n\u003cp\u003eHormones and neurotransmitters function as an interconnected network, constantly influencing one another. Chronic stress can disrupt cortisol and dopamine balance, oestrogen plays a role in serotonin production, progesterone modulates GABA activity, and DHEA and testosterone affect motivation, resilience, and mood. Evaluating both systems together provides a clearer understanding of the root causes behind symptoms such as fatigue, anxiety, mood instability, low libido, PMS, insomnia, and burnout.\u003c\/p\u003e\n\u003ch2\u003eThe Benefit of Adding Free Cortisol, Free Cortisone \u0026amp; Creatinine\u003c\/h2\u003e\n\u003cp\u003eIncluding Free Cortisol, Free Cortisone, and Creatinine alongside neurotransmitter analysis enhances the clinical value of the assessment.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eComprehensive Neuroendocrine Insight\u003c\/strong\u003e\u003cbr\u003eThis combined approach evaluates both hormonal stress markers and neurotransmitter pathways, offering a broader understanding of neuroendocrine balance.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStress Response Assessment\u003c\/strong\u003e\u003cbr\u003eFree Cortisol and Free Cortisone reflect adrenal activity and daily stress adaptation, helping to identify dysregulation linked to chronic stress and mood disorders.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMood \u0026amp; Cognitive Evaluation\u003c\/strong\u003e\u003cbr\u003eBy assessing stress hormones together with key neurotransmitters, the test clarifies how hormonal fluctuations may influence anxiety, depression, focus, and emotional resilience.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAdrenal Function Review\u003c\/strong\u003e\u003cbr\u003eCortisol and cortisone measurement supports evaluation of adrenal performance and potential dysfunction affecting both physical and mental health.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSleep \u0026amp; Energy Regulation\u003c\/strong\u003e\u003cbr\u003eCortisol rhythm and neurotransmitter balance are central to healthy sleep patterns and stable energy levels.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCreatinine Normalisation\u003c\/strong\u003e\u003cbr\u003eCreatinine ensures accurate interpretation of urinary neurotransmitter and hormone levels by correcting for urine concentration variability.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePersonalised Treatment Planning\u003c\/strong\u003e\u003cbr\u003eThe integrated results allow for more targeted clinical strategies, including nutritional, lifestyle, stress-management, and hormone-support interventions based on objective biochemical data.\u003c\/p\u003e\n\u003ch2\u003eKey Features\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eComprehensive Neurochemical Profile\u003c\/strong\u003e\u003cbr\u003eEvaluates a broad spectrum of neurotransmitters to provide detailed insight into overall brain chemistry and functional balance.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eObjective Biomarker Measurement\u003c\/strong\u003e\u003cbr\u003eDelivers precise, quantitative data to support clinical assessment and move beyond symptom-based evaluation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePersonalised Treatment Planning\u003c\/strong\u003e\u003cbr\u003eIdentifies specific imbalances to help guide tailored interventions, including medication optimisation, targeted nutritional support, and lifestyle strategies.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eClinical Diagnostic Support\u003c\/strong\u003e\u003cbr\u003eProvides objective information that complements psychological and medical evaluations, assisting in the assessment of conditions such as anxiety, depression, ADHD, and other neurological or psychiatric disorders.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTargeted Therapeutic Direction\u003c\/strong\u003e\u003cbr\u003eHighlights deficiencies or excesses within neurotransmitter pathways to enable focused and effective corrective strategies.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTreatment Monitoring\u003c\/strong\u003e\u003cbr\u003eAllows practitioners to track biochemical changes over time and adjust interventions based on measurable progress.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDifferential Insight\u003c\/strong\u003e\u003cbr\u003eSupports the distinction between overlapping symptoms and contributing neurochemical patterns across various conditions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIndividualised Nutritional Guidance\u003c\/strong\u003e\u003cbr\u003eReveals metabolic pathway patterns involving precursors, metabolites, enzymes, and cofactors to inform personalised nutritional recommendations.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHolistic Health Perspective\u003c\/strong\u003e\u003cbr\u003eRecognises the interaction between neurochemistry, hormones, stress, lifestyle, and environmental factors in overall wellbeing.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuitable for Adults and Children\u003c\/strong\u003e\u003cbr\u003eAppropriate for both adult and paediatric use when clinically indicated.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eConvenient At-Home Collection\u003c\/strong\u003e\u003cbr\u003eNon-invasive dried urine sampling collected four times throughout the day, with simple storage and return.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReliable Laboratory Analysis\u003c\/strong\u003e\u003cbr\u003eProvides accurate, timely, and dependable results.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eComprehensive Clinical Report\u003c\/strong\u003e\u003cbr\u003eIncludes a personalised, literature-referenced interpretation with practical treatment considerations.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDelivery:\u003c\/strong\u003eFree delivery in the UK \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eShipping:\u003c\/strong\u003e\u003c\/em\u003eCustomers are responsible for shipping their samples to the laboratory. \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eNo Additional Fee:\u003c\/strong\u003e\u003c\/em\u003eThe test kit includes a laboratory fee: no additional laboratory cost or tax.\u003c\/p\u003e\n\u003cp\u003eHow and when to Collect your saliva samples:\u003cstrong\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/saliva-testing-instructions.pdf?v=1648122023\"\u003eSaliva Testing Instructions\u003c\/a\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eClick to see \u0026gt;\u0026gt; \u003cstrong\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Saliva_Hormone_Test_Profile-III.pdf?11230793016030073961\"\u003eSample Saliva Test Result Report\u003c\/a\u003e and\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eClick to see \u0026gt;\u0026gt; \u003cstrong\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/advanced-neurotransmitters_7b487e14-4f01-4507-8446-edb06192ccaf.pdf?v=1589397181\"\u003eAdvanced Neurotransmitter Test Report\u003c\/a\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe test must be used within 12 months after the purchase date.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eTest Result Report: \u003c\/strong\u003e\u003c\/em\u003eYou will receive your test result via email within 3-5 working days after the Laboratory receives your sample. On your test result, you will find your hormone levels in graphics and numbers, which makes it easy to understand. You will also find the Laboratory's comments made by\u003cstrong\u003e Specialist PhD. Dr\u003c\/strong\u003e suggests how to balance your hormones if there are any imbalanced hormones and what to do next. \u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eThe Test Kit pack includes\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eTest Requisition Form includes Symptom Checklist\u003c\/li\u003e\n\u003cli\u003eRequisition Form to complete, including your personal and medical history\u003c\/li\u003e\n\u003cli\u003eContains collection instructions\u003c\/li\u003e\n\u003cli\u003eUrine Strips for collecting a dried urine sample and Tubes for collecting saliva samples\u003c\/li\u003e\n\u003cli\u003eInstructions on How to Use Collection Kit\u003c\/li\u003e\n\u003cli\u003eReturn Envelope\u003c\/li\u003e\n\u003cli\u003eShipping instruction\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eNEUROTRANSMITTERS PLAY A KEY ROLE\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eRegulation of Mood and Emotions\u003c\/strong\u003e\u003cbr\u003eNeurotransmitters such as serotonin, dopamine, and norepinephrine are central to emotional balance, motivation, and the experience of pleasure and reward. When these chemical messengers fall out of balance, symptoms associated with anxiety, depression, and bipolar disorder may develop.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eControl of Motor Functions\u003c\/strong\u003e\u003cbr\u003eAcetylcholine, dopamine, and GABA are essential for coordinating movement, muscle control, balance, and overall motor stability. Proper neurotransmitter signalling ensures smooth and controlled physical activity.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCognitive Function and Learning\u003c\/strong\u003e\u003cbr\u003eGlutamate, acetylcholine, and dopamine contribute to memory formation, attention, concentration, and information processing. These neurotransmitters support learning capacity and overall cognitive performance.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRegulation of Sleep and Wakefulness\u003c\/strong\u003e\u003cbr\u003eSerotonin and norepinephrine help regulate circadian rhythm and sleep architecture. Balanced neurotransmitter activity influences sleep quality, timing, and the transition between sleep stages.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eModulation of Pain Perception\u003c\/strong\u003e\u003cbr\u003eEndorphins and enkephalins assist in reducing the perception of pain by moderating pain signal transmission within the nervous system.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAutonomic Functions\u003c\/strong\u003e\u003cbr\u003eNeurotransmitters regulate essential involuntary functions, including heart rate, blood pressure, digestion, and respiration. Acetylcholine and norepinephrine are particularly important in autonomic nervous system control.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRegulation of Appetite and Satiety\u003c\/strong\u003e\u003cbr\u003eSerotonin and related neuropeptides influence appetite, satiety, and food intake. Disruptions may contribute to eating disorders or weight regulation challenges.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003eARE YOU AFFECTED?\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eMood Disorders\u003c\/strong\u003e\u003cbr\u003eAltered levels of serotonin, dopamine, and norepinephrine are frequently associated with depression, anxiety disorders, and bipolar disorder. Low serotonin may contribute to low mood, while dopamine imbalance can affect emotional stability.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCognitive Impairment\u003c\/strong\u003e\u003cbr\u003eNeurotransmitter dysregulation can impair memory, focus, and processing speed. For example, acetylcholine deficiencies are linked to cognitive decline and memory-related conditions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSleep Disturbances\u003c\/strong\u003e\u003cbr\u003eImbalanced neurotransmitters may disrupt sleep-wake cycles, contributing to insomnia, fragmented sleep, or excessive daytime fatigue.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNeurological Disorders\u003c\/strong\u003e\u003cbr\u003eDopamine disruption is associated with Parkinson’s disease, while imbalances in glutamate and GABA pathways are linked to seizure activity and epilepsy.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImpaired Motor Function\u003c\/strong\u003e\u003cbr\u003eDeficiencies in dopamine and related neurotransmitters can result in tremors, rigidity, and coordination difficulties.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAddiction and Substance Abuse\u003c\/strong\u003e\u003cbr\u003eDopamine plays a critical role in reward pathways. Dysregulation may increase susceptibility to addictive behaviours and substance dependence.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHormonal Imbalances\u003c\/strong\u003e\u003cbr\u003eNeurotransmitters influence endocrine function. Persistent imbalances may disrupt hormone production and metabolic regulation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDigestive Disorders\u003c\/strong\u003e\u003cbr\u003eSerotonin plays a significant role in gut function. Low or dysregulated levels may contribute to gastrointestinal conditions such as irritable bowel syndrome (IBS) and other functional digestive disturbances.\u003c\/p\u003e\n\u003ch2\u003eNeurotransmitters \u0026amp; Your Health\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eAnxiety and Depression\u003c\/strong\u003e\u003cbr\u003eImbalances in serotonin, norepinephrine, and dopamine are closely linked to anxiety and depressive disorders. Low serotonin levels are commonly associated with persistent low mood and anxious feelings, while disruptions in dopamine and norepinephrine may affect motivation, emotional stability, and stress resilience.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSleep Disorders\u003c\/strong\u003e\u003cbr\u003eNeurotransmitters regulate the sleep–wake cycle and overall sleep quality. Disturbances in serotonin and melatonin pathways can lead to difficulty falling asleep, staying asleep, or achieving restorative sleep. Reduced serotonin activity, for example, is often associated with insomnia.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLibido and Sexual Function\u003c\/strong\u003e\u003cbr\u003eDopamine plays a central role in the brain’s reward and pleasure pathways, including sexual desire. Neurotransmitter imbalances may contribute to reduced libido, diminished sexual satisfaction, or related dysfunction.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePremenstrual Symptoms\u003c\/strong\u003e\u003cbr\u003eFluctuations in serotonin and GABA levels may contribute to mood swings, irritability, and emotional sensitivity before menstruation. Neurotransmitter instability can intensify premenstrual symptoms and affect overall wellbeing.\u003c\/p\u003e\n\u003cp\u003eIf these symptoms are present, an underlying neurotransmitter imbalance may be contributing. Objective testing can help identify root causes and guide personalised strategies.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003eNeurotransmitters \u0026amp; Their Impact\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eCommunication\u003c\/strong\u003e\u003cbr\u003eNeurotransmitters are chemical messengers that transmit signals between nerve cells across synapses, enabling continuous communication between the brain and the body.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNeurological Function\u003c\/strong\u003e\u003cbr\u003eThey regulate sensory perception, motor control, cognition, memory, and emotional processing, ensuring coordinated nervous system activity.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePsychological Function\u003c\/strong\u003e\u003cbr\u003eBalanced neurotransmitter activity supports stable mood, motivation, and mental clarity. Imbalances may contribute to depression, anxiety, bipolar disorder, schizophrenia, and other psychiatric conditions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNeurotransmitter Imbalance\u003c\/strong\u003e\u003cbr\u003eBoth deficiency and excess can produce neurological and psychological symptoms. For example, low serotonin may be linked to depressive symptoms, while excessive dopamine activity may contribute to mood instability or psychosis.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImpact on Physical Health\u003c\/strong\u003e\u003cbr\u003eBeyond mental health, neurotransmitters influence autonomic functions such as heart rate, blood pressure, digestion, and metabolic regulation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTreatment Approaches\u003c\/strong\u003e\u003cbr\u003eUnderstanding neurotransmitter patterns can guide targeted interventions, including medication, nutritional strategies, therapy, and lifestyle modifications aimed at restoring balance.\u003c\/p\u003e\n\u003cp\u003eMaintaining optimal neurotransmitter balance is essential for both mental and physical health. When dysregulated, the brain and body may become overstimulated or underactive, leading to a wide range of symptoms.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eCan a Dysregulated Nervous System Impact Health?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eA dysregulated nervous system can significantly impact overall health, as neurotransmitters—like hormones—must remain in careful balance for the body to function optimally. Factors such as genetics, environmental stressors, chemical exposures, and nutritional deficiencies can disrupt neurotransmitter production, leading to either excess or deficiency. When this imbalance occurs, the nervous system attempts to compensate, but over time this adaptation may contribute to neurological or psychological symptoms. Many common mental health conditions are associated with neurotransmitter dysregulation; however, individuals with similar symptoms may have different underlying biochemical patterns. Objective testing helps identify these root imbalances and supports more targeted and personalised intervention strategies.\u003cstrong\u003e\u003cbr\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eNeurotransmitters \u0026amp; Symptoms\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDo These Symptoms Sound Familiar?\u003c\/strong\u003e\u003cbr\u003eIf you regularly experience three or more of the following symptoms, a neurotransmitter imbalance may be contributing: ADD\/ADHD, aggression, anxiety, fatigue, forgetfulness, hyperactivity, impulsive behaviours, insomnia, low libido, mood swings, obsessive-compulsive tendencies (OCD), panic attacks, poor concentration, PMDD, severe PMS, or persistent sleep problems. These symptoms often reflect underlying disruptions in serotonin, dopamine, GABA, and related pathways that influence mood, focus, behaviour, and emotional stability.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003eMale Hormone-Related Symptoms\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eMale Estrogen\/Progesterone Deficiency\u003c\/strong\u003e\u003cbr\u003eMay present with bone loss, depression, heart palpitations, hot flushes, neck or back pain, night sweats, and sleep difficulties.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMale Estrogen Dominance \/ Progesterone Deficiency\u003c\/strong\u003e\u003cbr\u003eCan include irritability, cold body temperature, low libido, prostate concerns, urinary changes, and weight gain around the chest or hips.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMale Low Androgens (DHEA\/Testosterone) Deficiency\u003c\/strong\u003e\u003cbr\u003eCommon signs include fatigue (morning or evening), reduced stamina, low libido, decreased muscle mass, joint pain, irritability, depression, brain fog, headaches, skin thinning, rapid ageing, waist weight gain, and elevated triglycerides.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMale Low Cortisol\u003c\/strong\u003e\u003cbr\u003eMay involve low blood pressure, low blood sugar, fatigue, dizziness, infertility, joint pain, irritability, sugar cravings, and reduced stress tolerance.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMale High Cortisol\u003c\/strong\u003e\u003cbr\u003eOften associated with anxiety, high blood pressure, sleep disturbance, depression, reduced muscle mass, central weight gain, skin thinning, and elevated triglycerides.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003eFemale Hormone-Related Symptoms\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eFemale Estrogen\/Progesterone Deficiency\u003c\/strong\u003e\u003cbr\u003eMay include hot flushes, night sweats, depression, foggy thinking, vaginal dryness, infertility, incontinence, bone loss, sleep disturbance, tearfulness, and waist weight gain.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFemale Estrogen Dominance \/ Progesterone Deficiency\u003c\/strong\u003e\u003cbr\u003eCommon signs include mood swings, irritability, anxiety, water retention, fibrocystic or tender breasts, headaches, uterine fibroids, bleeding changes, and hip weight gain.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFemale Low Androgens (DHEA\/Testosterone) Deficiency\u003c\/strong\u003e\u003cbr\u003eMay present with fatigue, decreased libido, reduced muscle tone, bone loss, memory lapse, vaginal dryness, skin thinning, and reduced stamina.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFemale High Androgens\u003c\/strong\u003e\u003cbr\u003eCan involve acne, increased facial or body hair, scalp hair loss, irritability, waist weight gain, and elevated triglycerides.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFemale Low Cortisol\u003c\/strong\u003e\u003cbr\u003eSymptoms may include low blood pressure, low blood sugar, fatigue, fibromyalgia-like pain, slow pulse, stress intolerance, and sugar cravings.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFemale High Cortisol\u003c\/strong\u003e\u003cbr\u003eOften associated with anxiety, sleep disturbance, depression, memory issues, hot flushes, rapid ageing, bone loss, uterine fibroids, and central weight gain.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003eTesting \u0026amp; Collection\u003c\/h2\u003e\n\u003cp\u003ePersistent symptoms may warrant comprehensive hormone and neurotransmitter evaluation. Saliva hormone testing measures cortisol, estrogen, progesterone, DHEA, and testosterone using a simple, non-invasive collection method. Samples are collected at home at specific times to ensure accurate hormone rhythm assessment.\u003c\/p\u003e\n\u003ch2\u003eNeurotransmitters and Children\u003c\/h2\u003e\n\u003cp\u003eNeurotransmitter imbalances can influence a child’s emotional, cognitive, and physical development. Disruptions in serotonin levels have been associated with anxiety, low mood, and emotional instability, while dopamine imbalances may contribute to attention deficit hyperactivity disorder (ADHD) and impulsive behaviour. Alterations in acetylcholine and glutamate pathways can affect memory, focus, and information processing, potentially impacting academic performance and learning capacity. Sleep disturbances may also arise when serotonin and melatonin regulation is impaired, leading to difficulty falling or staying asleep.\u003c\/p\u003e\n\u003cp\u003eIn some cases, neurotransmitter dysregulation has been linked to developmental conditions such as autism spectrum disorder (ASD), where imbalances in serotonin, dopamine, and GABA pathways may contribute to social communication challenges or repetitive behaviours. Sensory processing difficulties may also occur when neurotransmitter systems involved in sensory integration are disrupted. Because multiple factors—including genetics, early life experiences, environmental influences, and coexisting conditions—can affect neurotransmitter balance, professional assessment and individualised treatment planning are essential. Management strategies may include behavioural therapy, nutritional support, lifestyle interventions, and, when appropriate, medical treatment under specialist supervision.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNeurotransmitters You Should Know\u003c\/strong\u003e\u003cbr\u003eThere are many neurotransmitters in the body. The primary messengers are divided into two groups.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eExcitatory:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eInhibitory:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNeurotransmitter Imbalance \u0026amp; Chronic Conditions\u003cbr\u003e\u003c\/strong\u003eNumerous neurotransmitter imbalances may cause persistent health concerns:\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNeurotransmitter Testing – Giving a Diagnostic Edge in Treating Mood Disorders.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eMental health disorders affect millions of people and profoundly contribute to the burden of disease in society. \u003c\/p\u003e\n\u003cp\u003eThe current treatment paradigm in addressing poor brain health relies on diagnostic tools that encompass the evaluation of clinical signs and symptoms. Despite the lack of testable biomarkers for mood disorders, for many patients, treatments can generally be effective. However, even after treatment, frequent relapse episodes can still occur. Furthermore, a large number of patients suffer from treatment-resistant depression. Therefore, the selection of the best therapeutic regimen for each patient remains a challenge and is often discovered through a time-consuming process of trial and error. Also, no single approach works for everyone with any one disorder.\u003c\/p\u003e\n\u003cp\u003eTargeted neurotransmitter testing can help healthcare practitioners achieve a diagnostic edge beyond the traditional psychological inventory by identifying specific imbalances in neurotransmitter levels. Based on neurotransmitter test results, practitioners can identify specific biochemical heterogeneities for each particular patient and objectively monitor therapeutic responses during and after the intervention. Neurotransmitter testing objectively enhances medical assessment and represents a major advance in the personalization of the treatment of mood disorders.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow Neurotransmitters Relay Information within the Body\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe brain orchestrates the delicate interplay between the body and the mind. Structural brain units, the neurons, discharge neurotransmitters. These neurotransmitters provide a communication platform for the brain to fuel internal systems with information. Anything the body senses, feels, hears, smells, touches, or ingests serves as an input that prompts an astoundingly fast response. In the central and peripheral nervous system, neurotransmitters operate as chemical messengers that relay the signal and receive feedback via electrochemical impulses to regulate cognition, memory, emotions, respiration, heart rate and contractility, digestion, metabolism, blood flow and pressure, and hormonal responses. When released from peripheral organs, neurotransmitters can also behave as hormones by diffusing to distant sites via circulation.\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003eThe Benefit of Testing Saliva Hormone Tests with Neurotransmitters Test\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003eThe combined testing of saliva hormone levels, including Estradiol, Progesterone, Testosterone, DHEAS (DS), and Cortisol, with neurotransmitters provides several benefits in assessing and managing overall hormonal and neuroendocrine health. Here are the potential benefits of this comprehensive testing approach:\u003c\/p\u003e\n\u003cp\u003eBy combining saliva hormone testing for Estradiol, Progesterone, Testosterone, DHEAS (DS), and Cortisol with neurotransmitter analysis, a comprehensive assessment of hormonal and neuroendocrine health is achieved. This approach provides valuable insights into imbalances, stress response, and the interplay between hormones and neurotransmitters. Working with qualified healthcare professionals is essential to accurately interpret test results and develop tailored treatment plans that address individual needs and support optimal health and well-being.\u003c\/p\u003e\n\u003ch2\u003eClinical Utility \u0026amp; Validity of Urinary Neurotransmitter Testing\u003c\/h2\u003e\n\u003cp\u003eMood disorders are complex and often involve imbalances across multiple neurotransmitter systems interacting with hormones and the gut–brain axis. When these chemical messengers fall out of balance, symptoms such as anxiety, depression, fatigue, and cognitive difficulties may occur. Urinary neurotransmitter testing provides objective biochemical data that helps identify specific excesses or deficiencies, supporting more targeted and personalised treatment strategies rather than relying solely on trial-and-error approaches.\u003c\/p\u003e\n\u003cp\u003eAlthough urine testing is not a direct measurement of brain levels, urinary patterns often reflect systemic neurotransmitter activity and can provide meaningful insight into overall neurochemical regulation. This broader functional perspective assists healthcare providers in tailoring interventions based on measurable data.\u003c\/p\u003e\n\u003ch2\u003eDried Urine – A Convenient Option\u003c\/h2\u003e\n\u003cp\u003eDried urine collection is non-invasive and simple to perform at home. Instead of a 24-hour liquid collection, four small samples are collected at specific times during the day (morning, mid-morning, evening, and bedtime) using filter cards. Once dried, the samples are mailed to the laboratory. This method improves convenience, compliance, and practicality in clinical use.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eConsiderations \u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDopamine,\u003c\/strong\u003egenerally regarded as the brain’s pleasure and reward centre, plays the central role in addiction, improves attention, focus and motivation, and modulates movement control.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEpinephrine\u003c\/strong\u003e\u003cstrong\u003eand Norepinephrine\u003c\/strong\u003eregulate the “fight or flight” response, elevate blood pressure and heart rate, stimulate wakefulness and reduce digestive activity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGlutamate\u003c\/strong\u003efunctions as the “on” switch in the brain. It’s the major excitatory neurotransmitter that decreases sleep, optimizes learning, memory, and mood, and improves libido.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHistamine\u003c\/strong\u003eplays a role in the body as a neurotransmitter that increases metabolism, promotes wakefulness, and suppresses appetite.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePEA (phenylethylamine)\u003c\/strong\u003epromotes energy, elevates mood, regulates attention aggression and serves as a biomarker for ADHD.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGABA\u003c\/strong\u003efunctions as the “off” switch in the brain. It’s the major inhibitory neurotransmitter that improves mood, relieves anxiety, and promotes sleep.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGlycine\u003c\/strong\u003eplays a dual role as a neurotransmitter and amino acid that serves as a building block to proteins, improves sleep quality, calms aggression, and serves as an anti-inflammatory agent.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSerotonin\u003c\/strong\u003e, generally regarded as the “happiness molecule,” contributes to the feeling of calm and well-being that eases depression and anxiety, supports sleep and decreases appetite.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnxiety \u0026amp; Depression:\u003c\/strong\u003eImbalances are often associated with Glutamate (panic attacks), PEA, Histamine, Serotonin, as well as Epinephrine and Norepinephrine.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFatigue:\u003c\/strong\u003eAn imbalance between excitatory and inhibitory neurotransmitters is likely.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImpulsivity:\u003c\/strong\u003eGABA, Dopamine, and Serotonin are three chemical messengers commonly linked to disorders like ADD, ADHD, and OCD.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInsomnia:\u003c\/strong\u003eGlutamate, Histamine, Dopamine, GABA, and Serotonin are several chemical messengers often linked to sleep disturbances and insomnia.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePMS or PMDD:\u003c\/strong\u003eImbalances such as Serotonin, Dopamine, Norepinephrine, and GABA are often involved\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003eHormonal Balance Assessment: Saliva hormone testing allows for a precise evaluation of hormone levels, including Estron, Estriol, Estradiol, Progesterone, Testosterone, and DHEAS. This assessment helps identify hormonal imbalances that may be contributing to various symptoms and conditions, such as menstrual irregularities, infertility, mood swings, low libido, and fatigue.\u003c\/li\u003e\n\u003cli\u003eNeuroendocrine Function Evaluation: Neurotransmitters play a crucial role in regulating mood, behaviour, and cognitive function. By combining saliva hormone testing with neurotransmitter analysis, a comprehensive assessment of the neuroendocrine system is achieved. This provides insights into the interplay between hormones and neurotransmitters, offering a more complete understanding of the factors influencing mental and emotional well-being.\u003c\/li\u003e\n\u003cli\u003eStress Response Assessment: Cortisol, a stress hormone, affects multiple body systems and plays a role in managing stress. Measuring cortisol levels alongside neurotransmitter and hormone testing provides insights into the body's stress response and its impact on neuroendocrine balance. This information helps identify adrenal dysfunction, chronic stress, and its potential effects on mental and physical health.\u003c\/li\u003e\n\u003cli\u003ePersonalized Treatment Approach: The integration of saliva hormone testing with neurotransmitter analysis enables healthcare providers to develop personalized treatment plans. This comprehensive approach allows for targeted interventions, including hormone replacement therapy, nutritional support, stress management techniques, and lifestyle modifications tailored to address specific imbalances.\u003c\/li\u003e\n\u003cli\u003eImproved Symptom Management: By identifying and addressing hormone imbalances and neurotransmitter irregularities, this combined testing approach helps in managing symptoms associated with hormonal and neuroendocrine disorders. It provides valuable insights for optimizing hormone levels and supporting overall well-being.\u003c\/li\u003e\n\u003cli\u003eOptimized Neuroendocrine Health: The comprehensive evaluation of both hormone levels and neurotransmitters supports the optimization of neuroendocrine health. It allows for a more thorough understanding of the underlying factors contributing to symptoms, offering an opportunity for targeted interventions and improved overall health outcomes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003eThe neurotransmitter test assumes proper kidney function. Neurotransmitter levels are reported in µg\/g creatinine, where creatinine is measured from the same sample. This test should not be used in individuals with compromised renal function. \u003c\/li\u003e\n\u003cli\u003eThe sample can become very dilute due to increased fluid consumption during the day. Therefore, on the day of testing, individuals should restrict their liquid intake to normal consumption.\u003c\/li\u003e\n\u003cli\u003eOn the day of testing, individuals are advised to refrain from consuming alcohol, nicotine, bananas, pineapple, and walnuts as they may interfere with testing.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003chr\u003e","brand":"ZRT Lab","offers":[{"title":"Default Title","offer_id":57861066228093,"sku":"NT-HORM-I-01","price":580.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Neurotransmitters_Test.webp?v=1785073865","url":"https:\/\/hormonelab.co.uk\/products\/advanced-neurotransmitter-hormone-test-i","provider":"Hormone Lab UK","version":"1.0","type":"link"}