{"product_id":"male-hormone-health-test-kit","title":"Male Hormone Health Test | Specialist Doctor Report Included","description":"\u003cp\u003e\u003cstrong\u003eTest ID: SB-643 | Saliva 4-Point Cortisol + Blood Spot LCMS Hormones 7 with SHBG\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe \u003cstrong\u003eMale Hormone Health Test\u003c\/strong\u003e is the most comprehensive at-home hormone profile available for men, measuring \u003cstrong\u003e15 key hormones and markers\u003c\/strong\u003e via a combination of saliva 4-point cortisol and blood spot LCMS testing. It is designed to provide a clinically complete picture of androgenic health, adrenal stress load, oestrogen balance, and the binding protein that governs how much of your hormones are actually available to drive energy, performance, libido, and metabolic function.\u003c\/p\u003e\n\u003cp\u003eWhat distinguishes this test is the inclusion of \u003cstrong\u003eSHBG (Sex Hormone Binding Globulin)\u003c\/strong\u003e alongside the full sex hormone panel. SHBG determines the proportion of testosterone and oestradiol that is free and active versus bound and unavailable. Two men with identical total testosterone levels can have completely different symptoms depending on their SHBG — one bound and symptomatic despite “normal” results, one free and functional. This test measures both total and free hormone availability, delivering a level of clinical insight that standard NHS blood tests do not provide.\u003c\/p\u003e\n\u003cp\u003eTest from home with confidence — no clinic visit required. Results within \u003cstrong\u003e3–5 working days\u003c\/strong\u003e.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003eWhy This Test Is Uniquely Suited to Men\u003c\/h2\u003e\n\u003cp\u003eMale hormonal health is governed by the interaction between testosterone, oestradiol, progesterone, DHEAS, cortisol, and SHBG — not by total testosterone alone:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSHBG determines your free testosterone — the only testosterone that matters\u003c\/strong\u003e — high SHBG (driven by ageing, low insulin, thyroid dysfunction, or alcohol) binds testosterone tightly, leaving insufficient free testosterone despite normal total levels; this is one of the most common causes of low-testosterone symptoms in men with “normal” blood results; low SHBG (driven by insulin resistance, visceral fat, or high androgens) releases excess free testosterone and oestradiol, increasing cardiovascular and prostate risk; without SHBG, total testosterone is clinically incomplete\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOestradiol is essential in men but easily imbalanced\u003c\/strong\u003e — men need oestradiol for bone density, cardiovascular protection, cognitive function, and libido; but excess oestradiol — from aromatase activity in visceral fat, alcohol, or ageing — suppresses testosterone, causes gynaecomastia, drives water retention, reduces sexual function, and is directly exacerbated by low SHBG; only measuring oestradiol alongside testosterone and SHBG reveals whether the ratio is clinically appropriate\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProgesterone in men is the overlooked androgenic regulator\u003c\/strong\u003e — progesterone inhibits 5-alpha reductase, blocking the conversion of testosterone to DHT; it has direct anti-oestrogenic, neuroprotective, and anti-inflammatory effects; low progesterone in men increases DHT, driving scalp hair loss, prostate enlargement risk, acne, and anxiety; it also supports thyroid function and sleep quality in men\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDHEAS is the adrenal androgen reserve\u003c\/strong\u003e — the primary precursor for testosterone and oestrogen synthesis in peripheral tissues, declining from the mid-30s and depleted under chronic stress; low DHEAS is associated with fatigue, reduced testosterone precursor availability, low libido, poor stress resilience, and accelerated hormonal ageing; elevated DHEAS under stress or overtraining drives androgen excess and cardiovascular risk\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCortisol suppresses testosterone at every level of the axis\u003c\/strong\u003e — through pregnenolone steal, direct Leydig cell suppression, and HPA axis dysregulation, chronic cortisol excess depletes testosterone, drives visceral fat and aromatase activity, elevates SHBG, and disrupts overnight testosterone production during deep sleep; the 4-point profile identifies the precise pattern and severity\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAll three oestrogens reveal oestrogen metabolism, not just oestradiol\u003c\/strong\u003e — measuring oestrone (E1) — the adipose-derived oestrogen — alongside oestradiol (E2) and oestriol (E3) reveals whether excess oestrogen is being generated from visceral fat, how oestrogen is being metabolised, and whether the overall oestrogenic load is contributing to testosterone suppression and cardiovascular risk\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eWhat This Test Measures\u003c\/h2\u003e\n\u003ch3\u003eSaliva — 4-Point Cortisol\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCortisol (C) — Morning:\u003c\/strong\u003e The Cortisol Awakening Response — the morning surge that activates metabolism, sets testosterone availability, and establishes cognitive and physical readiness for the day. A blunted response signals adrenal burnout and impaired overnight recovery; an exaggerated response indicates high stress reactivity and morning testosterone suppression.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCortisol (C) — Noon:\u003c\/strong\u003e Elevated noon cortisol in men promotes insulin resistance, visceral fat accumulation, and aromatase-driven testosterone-to-oestradiol conversion — directly raising SHBG and suppressing free testosterone availability in the most metabolically active part of the day.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCortisol (C) — Evening:\u003c\/strong\u003e Should be declining significantly to allow testosterone and growth hormone to begin rising during early sleep cycles. Elevated evening cortisol in men directly suppresses overnight hormonal recovery and elevates SHBG through hepatic cortisol-SHBG coupling.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCortisol (C) — Night:\u003c\/strong\u003e Elevated night cortisol suppresses the deep sleep phases during which the majority of daily testosterone is produced. It also promotes visceral fat accumulation and overnight blood sugar dysregulation — both primary drivers of aromatase activity and oestradiol excess in men.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eBlood Spot — Full Sex Hormone Panel with SHBG (LCMS)\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOestradiol (E2):\u003c\/strong\u003e Present in men via aromatase conversion of testosterone. Critical for bone density, cardiovascular health, and cognitive function — but excess oestradiol suppresses testosterone, causes gynaecomastia, increases water retention, and reduces libido. The oestradiol-to-testosterone ratio, interpreted alongside SHBG, is one of the most clinically important values in male hormonal health.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOestriol (E3):\u003c\/strong\u003e Reflects oestrogen conversion pathways and metabolic activity in men. Elevated E3 can indicate excessive aromatase activity or oestrogen precursor load; the ratio of E3 to E2 provides additional context for oestrogen metabolism beyond what E2 alone reveals.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOestrone (E1):\u003c\/strong\u003e Produced by conversion of androgens (particularly DHEAS) in adipose tissue. Elevated oestrone in men with visceral fat drives systemic oestrogenic load, compounds testosterone suppression, and is associated with increased cardiovascular and metabolic risk. A key marker for men carrying excess abdominal weight.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProgesterone (Pg):\u003c\/strong\u003e Present in men in small but clinically important amounts. Acts as a natural 5-alpha reductase inhibitor, blocking DHT conversion from testosterone; has direct anti-oestrogenic, neuroprotective, and anti-inflammatory effects; and supports sleep quality and thyroid function. Low progesterone in men is associated with elevated DHT, prostate risk, scalp hair loss, anxiety, and poor sleep recovery.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTestosterone (T):\u003c\/strong\u003e The primary male androgen — responsible for energy, libido, muscle mass, bone density, cognitive performance, and mood. Blood spot LCMS measures total testosterone; interpreted alongside SHBG, this provides the free testosterone estimate that determines whether symptoms of deficiency are likely. Both low and high-normal total testosterone carry different clinical implications depending on SHBG status.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDHEAS (DS):\u003c\/strong\u003e The primary adrenal androgen precursor in men, declining steadily from the mid-30s. Low DHEAS reduces testosterone precursor availability, impairs stress resilience, and is associated with fatigue, reduced libido, and accelerated hormonal ageing. Elevated DHEAS — from adrenal overactivity or overtraining — drives androgen excess and raises cardiovascular inflammatory risk.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCortisol (C) — Blood Spot:\u003c\/strong\u003e Provides the absolute cortisol value that anchors the 4-point saliva cortisol profile and confirms adrenal output at the time of blood spot collection.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSHBG (Sex Hormone Binding Globulin):\u003c\/strong\u003e The transport protein that binds testosterone and oestradiol, determining how much free (active) hormone is available to cells and tissues. High SHBG in men — driven by ageing, thyroid dysfunction, low insulin, or alcohol — reduces free testosterone and free oestradiol, producing symptoms of hormone deficiency with apparently normal total hormone levels. Low SHBG — driven by insulin resistance, visceral fat, or elevated insulin — releases excess free testosterone and oestradiol, driving androgen excess, cardiovascular risk, and oestrogen imbalance. SHBG is directly affected by cortisol, thyroid function, insulin, and liver health — making it a critical interpretive marker for the entire male hormone panel.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cp\u003eThis test is particularly relevant for men who experience:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePersistent fatigue or exhaustion that does not improve with rest or sleep\u003c\/li\u003e\n\u003cli\u003eLow libido or reduced sexual interest\u003c\/li\u003e\n\u003cli\u003eErectile dysfunction or reduced sexual performance\u003c\/li\u003e\n\u003cli\u003eUnexplained weight gain or difficulty losing body fat, particularly around the abdomen\u003c\/li\u003e\n\u003cli\u003ePoor recovery from exercise, training, or sustained high workload\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor concentration, or reduced cognitive sharpness\u003c\/li\u003e\n\u003cli\u003eLow mood, reduced motivation, or mild depression\u003c\/li\u003e\n\u003cli\u003eInsomnia, night waking, or unrefreshing sleep\u003c\/li\u003e\n\u003cli\u003eChronic stress, burnout, or sustained high workload\u003c\/li\u003e\n\u003cli\u003eFeeling cold all the time or temperature sensitivity\u003c\/li\u003e\n\u003cli\u003eDry skin, hair thinning, or slow wound healing\u003c\/li\u003e\n\u003cli\u003eAcne, oily skin, or scalp hair loss alongside other hormonal symptoms\u003c\/li\u003e\n\u003cli\u003eGynaecomastia or breast tissue sensitivity\u003c\/li\u003e\n\u003cli\u003eSymptoms of low testosterone with normal standard blood results\u003c\/li\u003e\n\u003cli\u003eCurrently on TRT and wanting a comprehensive hormonal picture including SHBG and oestradiol\u003c\/li\u003e\n\u003cli\u003eFamily history of prostate disease, cardiovascular disease, or metabolic syndrome\u003c\/li\u003e\n\u003cli\u003eMen over 35 wanting a complete androgenic and stress hormone health baseline\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eKey Features\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e15-marker combined saliva cortisol and blood spot LCMS hormone panel\u003c\/li\u003e\n\u003cli\u003eSHBG included — the only way to assess free hormone availability and the true androgenic picture\u003c\/li\u003e\n\u003cli\u003eAll three oestrogens (E1, E2, E3) measured for complete oestrogen metabolism and oestrogenic load assessment in men\u003c\/li\u003e\n\u003cli\u003e4-point cortisol profile revealing the full daily adrenal rhythm and its impact on testosterone and SHBG\u003c\/li\u003e\n\u003cli\u003eResults within \u003cstrong\u003e3–5 working days\u003c\/strong\u003e after lab receipt\u003c\/li\u003e\n\u003cli\u003eExpert analysis by a \u003cstrong\u003eHormone Specialist PhD Doctor\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003eClear graphical and numerical results with personalised commentary\u003c\/li\u003e\n\u003cli\u003eAll-inclusive price — laboratory fees included, no hidden costs\u003c\/li\u003e\n\u003cli\u003eValid for 12 months from purchase\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrder the kit online\u003c\/strong\u003e — delivered directly to your door.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCollect your saliva samples\u003c\/strong\u003e at four time points (morning, noon, evening, night) and your \u003cstrong\u003eblood spot sample\u003c\/strong\u003e via a simple finger-prick, following the detailed instructions provided. Morning saliva should be collected before 9am for optimal cortisol accuracy.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePost your samples to the lab\u003c\/strong\u003e using the return instructions included in your kit.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReceive your results within 3–5 working days\u003c\/strong\u003e, with specialist commentary and clear next-step guidance.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003chr\u003e\n\u003ch2\u003eWhat Your Report Includes\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll 15 marker results with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eVisual charts for your 4-point cortisol daily curve and full sex hormone panel including SHBG\u003c\/li\u003e\n\u003cli\u003eClinical interpretation of your free versus bound testosterone based on your SHBG result\u003c\/li\u003e\n\u003cli\u003eAnalysis of your oestradiol-to-testosterone ratio and oestrogenic load\u003c\/li\u003e\n\u003cli\u003eSpecialist commentary by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eWhat does this test measure?\u003c\/h3\u003e\n\u003cp\u003e4-point Cortisol (saliva: morning, noon, evening, night) plus Oestradiol (E2), Oestriol (E3), Oestrone (E1), Progesterone, Testosterone, DHEAS, Cortisol, and SHBG (blood spot LCMS) — 15 markers in total.\u003c\/p\u003e\n\u003ch3\u003eWhy is SHBG important for men?\u003c\/h3\u003e\n\u003cp\u003eSHBG determines how much of your testosterone is free and active versus bound and unavailable. Two men with identical total testosterone of 20 nmol\/L can have very different free testosterone — one with high SHBG may be functionally testosterone-deficient despite “normal” results; one with low SHBG may have excess free testosterone driving prostate and cardiovascular risk. Without SHBG, a testosterone result alone cannot tell you whether your symptoms are explained by your hormone levels.\u003c\/p\u003e\n\u003ch3\u003eWhy do men need oestrogen tested?\u003c\/h3\u003e\n\u003cp\u003eMen produce oestradiol through aromatase conversion of testosterone — a process that increases with visceral fat, alcohol, and ageing. Oestradiol is essential for bone health, cardiovascular protection, and cognitive function in men, but excess oestradiol suppresses testosterone, causes gynaecomastia, and drives fat accumulation. Measuring all three oestrogens alongside testosterone and SHBG reveals the full oestrogenic load and its impact on androgenic balance.\u003c\/p\u003e\n\u003ch3\u003eCan I use this test if I am on TRT?\u003c\/h3\u003e\n\u003cp\u003eYes. This test is particularly valuable for men on TRT who want to understand their oestradiol balance, SHBG status, and cortisol pattern alongside testosterone. TRT increases aromatisation and can significantly alter SHBG — making a comprehensive panel essential for monitoring therapy safely and optimally.\u003c\/p\u003e\n\u003ch3\u003eWhy measure cortisol at four time points?\u003c\/h3\u003e\n\u003cp\u003eA single cortisol measurement cannot distinguish between adrenal burnout (low flat curve), high reactivity (elevated morning peak), evening elevation (suppressed overnight testosterone), or night excess (disrupted deep sleep and testosterone production). The 4-point profile captures the full adrenal daily rhythm and reveals how cortisol is specifically affecting your testosterone, SHBG, and oestrogenic balance.\u003c\/p\u003e\n\u003ch3\u003eWhen will I get my results?\u003c\/h3\u003e\n\u003cp\u003eWithin \u003cstrong\u003e3–5 working days\u003c\/strong\u003e after your samples reach the laboratory.\u003c\/p\u003e\n\u003ch3\u003eAre there hidden costs?\u003c\/h3\u003e\n\u003cp\u003eNo. Laboratory analysis and specialist review are fully included. You are responsible for postage to the lab.\u003c\/p\u003e\n\u003ch3\u003eHow long is the kit valid?\u003c\/h3\u003e\n\u003cp\u003e12 months from purchase.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003eWhy We Partner with ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAt Hormone Lab UK, every home test kit is analysed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e, a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic and research laboratory specialising in hormone testing, thyroid testing, fertility testing, adrenal function, neurotransmitter analysis, cardiometabolic health, heavy metals, and wellness testing. Founded in 1998 by renowned biochemist and breast cancer researcher \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e, ZRT has become one of the world’s leading laboratories for advanced functional health testing.\u003c\/p\u003e\n\u003cp\u003eWith \u003cstrong\u003emore than 11 million laboratory tests\u003c\/strong\u003e performed and healthcare professionals in \u003cstrong\u003eover 96 countries\u003c\/strong\u003e relying on its expertise, ZRT is recognised for scientific excellence, analytical accuracy, and continuous innovation. The laboratory pioneered \u003cstrong\u003eat-home saliva hormone testing\u003c\/strong\u003e, introduced the \u003cstrong\u003efirst commercially available dried blood spot (DBS) hormone tests\u003c\/strong\u003e, and developed \u003cstrong\u003eDried Urine Testing (DUTS)\u003c\/strong\u003e, helping make advanced laboratory diagnostics more accessible and clinically meaningful.\u003c\/p\u003e\n\u003cp\u003eEvery sample is analysed using state-of-the-art \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e and \u003cstrong\u003eICP-MS\u003c\/strong\u003e technology under rigorous quality control standards. ZRT collaborates with the \u003cstrong\u003eCDC\u003c\/strong\u003e, \u003cstrong\u003eNIH\u003c\/strong\u003e, and leading universities, supporting ongoing research and advances in laboratory medicine.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":57961734177149,"sku":"2022","price":358.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/SalivaandBloodSpotHormoneTestKit.webp?v=1785073903","url":"https:\/\/hormonelab.co.uk\/pl\/products\/male-hormone-health-test-kit","provider":"Hormone Lab UK","version":"1.0","type":"link"}