{"product_id":"female-cardiometabolic-thyroid-test-kit","title":"Female CardioMetabolic \u0026 Thyroid Test Kit | Specialist Doctor Report Included","description":"\u003cp\u003e\u003cstrong\u003eTest ID: SB-642 | Saliva 4-Point Cortisol + Blood Spot Thyroid \u0026amp; CardioMetabolic Panel\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe \u003cstrong\u003eFemale CardioMetabolic \u0026amp; Thyroid Test Kit\u003c\/strong\u003e is the most comprehensive at-home multi-system hormone test available for women, measuring \u003cstrong\u003e13 key markers\u003c\/strong\u003e across thyroid function, stress hormone rhythm, blood sugar regulation, inflammation, and cardiovascular health. It combines a \u003cstrong\u003e4-point saliva cortisol profile\u003c\/strong\u003e with a \u003cstrong\u003efull blood spot thyroid and cardiometabolic panel\u003c\/strong\u003e — delivering a clinically meaningful picture of the interconnected systems most responsible for energy, weight, mood, and long-term health in women.\u003c\/p\u003e\n\u003cp\u003eIn women, thyroid function, cortisol, blood sugar, and cardiovascular risk do not operate in isolation. They form a tightly interdependent network that is continuously modulated by oestrogen, progesterone, and the hormonal shifts of the menstrual cycle, perimenopause, and menopause. When one system is dysregulated, the others typically follow. This test is designed to assess all of them together — providing the complete hormonal and metabolic picture that standard GP blood panels do not offer.\u003c\/p\u003e\n\u003cp\u003eTest from home with confidence — no clinic visit required. Results within \u003cstrong\u003e3–5 working days\u003c\/strong\u003e.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003eWhy This Test Is Particularly Important for Women\u003c\/h2\u003e\n\u003cp\u003eWomen face a unique constellation of metabolic and thyroid risks that are directly shaped by female hormonal biology:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eThyroid disease is up to 10 times more common in women than men\u003c\/strong\u003e — and is frequently misattributed to stress, depression, or perimenopause; standard TSH-only testing misses early dysfunction, cortisol-driven T3 suppression, and autoimmune thyroid disease (Hashimoto’s)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOestrogen fluctuations directly affect thyroid hormone binding\u003c\/strong\u003e — rising oestrogen (during the luteal phase, pregnancy, or HRT) increases thyroid-binding globulin, reducing free T3 and T4 availability and producing hypothyroid symptoms with a normal TSH\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCortisol suppresses T3 conversion\u003c\/strong\u003e — chronic stress diverts T4 towards inactive reverse T3; this is one of the most common causes of fatigue, weight gain, and brain fog in women with “normal” thyroid blood tests\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInsulin resistance in women is hormonally driven\u003c\/strong\u003e — cortisol, low progesterone, and declining oestrogen all impair insulin sensitivity; PCOS is characterised by insulin resistance even in lean women, and perimenopause markedly increases metabolic risk\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCardiovascular risk rises sharply after perimenopause\u003c\/strong\u003e — declining oestrogen raises LDL and triglycerides, reduces HDL, and promotes vascular inflammation (measured by hsCRP); women’s cardiovascular risk is systematically underestimated and undertreated\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInflammation is the common root\u003c\/strong\u003e — elevated hsCRP connects thyroid autoimmunity, insulin resistance, cortisol dysregulation, and cardiovascular risk in a single underlying inflammatory process that this panel is uniquely positioned to reveal\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eWhat This Test Measures\u003c\/h2\u003e\n\u003ch3\u003eBlood Spot — Full Thyroid Panel\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTSH (Thyroid Stimulating Hormone):\u003c\/strong\u003e The standard first-line thyroid screen — but in women, TSH alone misses early dysfunction, HRT-related changes in thyroid binding, and cortisol-driven T3 suppression. Essential context, not a complete picture.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFree T3 (FT3):\u003c\/strong\u003e The active thyroid hormone that drives metabolism, energy, mood, and temperature regulation in women. Low FT3 with normal TSH is the most common missed thyroid pattern in women under chronic stress or hormonal transition.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFree T4 (FT4):\u003c\/strong\u003e The thyroid’s primary output hormone. Low FT4 with normal TSH indicates early thyroid insufficiency or impaired conversion — often preceding overt hypothyroidism by years, particularly in perimenopausal women.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTotal T4 (TT4):\u003c\/strong\u003e Measures total circulating T4 including the bound fraction. Particularly relevant for women on HRT or the contraceptive pill, which increase thyroid-binding globulin and alter the ratio of free to bound T4.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTPO Antibodies (Anti-TPO):\u003c\/strong\u003e The primary marker for Hashimoto’s thyroiditis — the autoimmune condition responsible for the majority of hypothyroidism in women. Elevated TPO antibodies are frequently present years before TSH becomes abnormal.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThyroglobulin Antibodies (Anti-Tg):\u003c\/strong\u003e A second autoimmune marker essential for complete Hashimoto’s screening; some women have elevated Tg antibodies with normal TPO, making both necessary for accurate autoimmune thyroid assessment.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eBlood Spot — CardioMetabolic Panel\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFasting Insulin:\u003c\/strong\u003e The earliest detectable marker of insulin resistance — elevated years before HbA1c or fasting glucose becomes abnormal. Insulin resistance in women is directly driven by cortisol, low progesterone, and the hormonal changes of perimenopause and PCOS.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHbA1c (Glycated Haemoglobin):\u003c\/strong\u003e Reflects average blood sugar over the preceding 8–12 weeks. A key marker for pre-diabetes and type 2 diabetes risk — which increases significantly after menopause as oestrogen’s insulin-sensitising effects decline.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHDL Cholesterol:\u003c\/strong\u003e The protective cholesterol fraction — directly supported by oestrogen; HDL typically falls after menopause, increasing cardiovascular risk in women who were previously well-protected.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTriglycerides:\u003c\/strong\u003e Elevated triglycerides are strongly associated with insulin resistance, high cortisol, and oestrogen decline in women; a key cardiometabolic risk marker often elevated before LDL changes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTotal Cholesterol:\u003c\/strong\u003e Provides the overall lipid context; rising total cholesterol in perimenopausal and postmenopausal women is a direct consequence of declining oestrogen.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ehsCRP (High-Sensitivity C-Reactive Protein):\u003c\/strong\u003e The gold standard inflammatory marker. Elevated hsCRP in women is associated with thyroid autoimmunity, insulin resistance, oestrogen decline, and increased cardiovascular risk — and is one of the strongest predictors of future heart disease in women, often more so than LDL cholesterol.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSaliva — 4-Point Cortisol Profile\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMorning Cortisol:\u003c\/strong\u003e The Cortisol Awakening Response — critical for energy, thyroid hormone activation, and progesterone balance. A blunted response in women signals adrenal burnout; elevated response indicates high stress reactivity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNoon Cortisol:\u003c\/strong\u003e Chronically elevated noon cortisol in women drives blood sugar instability, impairs T3 conversion, and worsens insulin resistance — often worsening in the luteal phase of the cycle.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvening Cortisol:\u003c\/strong\u003e Should be declining significantly to allow progesterone, melatonin, and thyroid cellular uptake to proceed during sleep. Elevated evening cortisol disrupts hormonal restoration in women.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNight Cortisol:\u003c\/strong\u003e Elevated night cortisol is a leading cause of insomnia, night sweats, and overnight blood sugar dysregulation in women — particularly during perimenopause and menopause.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cp\u003eThis test is particularly relevant for women who experience:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePersistent fatigue or exhaustion that does not improve with sleep or rest\u003c\/li\u003e\n\u003cli\u003eUnexplained weight gain or difficulty losing weight despite diet and exercise\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor memory, or difficulty concentrating\u003c\/li\u003e\n\u003cli\u003eLow mood, anxiety, or depression\u003c\/li\u003e\n\u003cli\u003eFeeling cold all the time, or temperature sensitivity\u003c\/li\u003e\n\u003cli\u003eDry skin, hair thinning or loss, or brittle nails\u003c\/li\u003e\n\u003cli\u003eIrregular, heavy, or absent periods\u003c\/li\u003e\n\u003cli\u003ePerimenopausal or menopausal symptoms including hot flushes, night sweats, and mood changes\u003c\/li\u003e\n\u003cli\u003ePCOS or known insulin resistance\u003c\/li\u003e\n\u003cli\u003eInsomnia, night waking, or unrefreshing sleep\u003c\/li\u003e\n\u003cli\u003eSugar cravings, energy crashes, or afternoon dips\u003c\/li\u003e\n\u003cli\u003eElevated cholesterol or triglycerides on previous testing\u003c\/li\u003e\n\u003cli\u003eFamily history of thyroid disease, diabetes, or heart disease\u003c\/li\u003e\n\u003cli\u003eCurrently on HRT or the contraceptive pill\u003c\/li\u003e\n\u003cli\u003eChronic stress or burnout\u003c\/li\u003e\n\u003cli\u003eWanting a comprehensive metabolic and hormonal baseline before or during perimenopause\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eKey Features\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e13-marker thyroid, cortisol, and cardiometabolic panel in a single at-home kit\u003c\/li\u003e\n\u003cli\u003eBlood spot collection — simple finger-prick, no clinic visit or venepuncture\u003c\/li\u003e\n\u003cli\u003eSaliva collection for cortisol — non-invasive, captures bioavailable (active) cortisol at four time points\u003c\/li\u003e\n\u003cli\u003eResults within \u003cstrong\u003e3–5 working days\u003c\/strong\u003e after lab receipt\u003c\/li\u003e\n\u003cli\u003eExpert analysis by a \u003cstrong\u003eHormone Specialist PhD Doctor\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003eClear graphical and numerical results with personalised commentary\u003c\/li\u003e\n\u003cli\u003eAll-inclusive price — laboratory fees included, no hidden costs\u003c\/li\u003e\n\u003cli\u003eValid for 12 months from purchase\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrder the kit online\u003c\/strong\u003e — delivered directly to your door.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCollect your blood spot sample\u003c\/strong\u003e via a simple finger-prick onto the collection card, and your \u003cstrong\u003esaliva samples\u003c\/strong\u003e at four time points across the day, following the detailed instructions provided. Guidance on optimal cycle timing is included.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePost your samples to the lab\u003c\/strong\u003e using the return instructions included in your kit.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReceive your results within 3–5 working days\u003c\/strong\u003e, with specialist commentary and clear next-step guidance.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003chr\u003e\n\u003ch2\u003eWhat Your Report Includes\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll 13 marker results with female-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eVisual charts for your cortisol daily curve, thyroid panel, and cardiometabolic markers\u003c\/li\u003e\n\u003cli\u003eClinical interpretation of how your thyroid, cortisol, and metabolic results interact — including oestrogen’s role in your results\u003c\/li\u003e\n\u003cli\u003eSpecialist commentary by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eWhat does this test measure?\u003c\/h3\u003e\n\u003cp\u003eTSH, Free T3, Free T4, Total T4, TPO Antibodies, Thyroglobulin Antibodies, Fasting Insulin, HbA1c, HDL Cholesterol, Triglycerides, Total Cholesterol, hsCRP (blood spot) plus 4-point Cortisol (saliva) — 13 markers in total.\u003c\/p\u003e\n\u003ch3\u003eWhy test thyroid, cortisol, and cardiometabolic markers together?\u003c\/h3\u003e\n\u003cp\u003eIn women, these systems are tightly interconnected through oestrogen, progesterone, and insulin. Cortisol suppresses thyroid T3 conversion; insulin resistance worsens with cortisol elevation and oestrogen decline; cardiovascular risk rises as thyroid and metabolic function deteriorates. Testing all together reveals the full picture — and the root cause — in a single kit.\u003c\/p\u003e\n\u003ch3\u003eCan I use this test if I am on HRT, the contraceptive pill, or levothyroxine?\u003c\/h3\u003e\n\u003cp\u003eYes. HRT and the pill affect thyroid hormone binding and lipid profiles, which is precisely why a comprehensive panel including FT3, FT4, and TT4 provides more useful information than TSH alone. Follow the timing guidance in your kit.\u003c\/p\u003e\n\u003ch3\u003eWhen should I collect my samples during my cycle?\u003c\/h3\u003e\n\u003cp\u003eGuidance on optimal cycle timing for both the blood spot and saliva samples is included in the kit.\u003c\/p\u003e\n\u003ch3\u003eHow accurate is the test?\u003c\/h3\u003e\n\u003cp\u003eBlood spot samples are analysed using advanced immunoassay technology; saliva cortisol is measured using \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e — the gold standard for bioavailable hormone measurement.\u003c\/p\u003e\n\u003ch3\u003eWhen will I get my results?\u003c\/h3\u003e\n\u003cp\u003eWithin \u003cstrong\u003e3–5 working days\u003c\/strong\u003e after your samples reach the laboratory.\u003c\/p\u003e\n\u003ch3\u003eAre there hidden costs?\u003c\/h3\u003e\n\u003cp\u003eNo. Laboratory analysis and specialist review are fully included. You are responsible for postage to the lab.\u003c\/p\u003e\n\u003ch3\u003eHow long is the kit valid?\u003c\/h3\u003e\n\u003cp\u003e12 months from purchase.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003eWhy We Partner with ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAt Hormone Lab UK, every home test kit is analysed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e, a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic and research laboratory specialising in hormone testing, thyroid testing, fertility testing, adrenal function, neurotransmitter analysis, cardiometabolic health, heavy metals, and wellness testing. Founded in 1998 by renowned biochemist and breast cancer researcher \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e, ZRT has become one of the world’s leading laboratories for advanced functional health testing.\u003c\/p\u003e\n\u003cp\u003eWith \u003cstrong\u003emore than 11 million laboratory tests\u003c\/strong\u003e performed and healthcare professionals in \u003cstrong\u003eover 96 countries\u003c\/strong\u003e relying on its expertise, ZRT is recognised for scientific excellence, analytical accuracy, and continuous innovation. The laboratory pioneered \u003cstrong\u003eat-home saliva hormone testing\u003c\/strong\u003e, introduced the \u003cstrong\u003efirst commercially available dried blood spot (DBS) hormone tests\u003c\/strong\u003e, and developed \u003cstrong\u003eDried Urine Testing (DUTS)\u003c\/strong\u003e, helping make advanced laboratory diagnostics more accessible and clinically meaningful.\u003c\/p\u003e\n\u003cp\u003eEvery sample is analysed using state-of-the-art \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e and \u003cstrong\u003eICP-MS\u003c\/strong\u003e technology under rigorous quality control standards. ZRT collaborates with the \u003cstrong\u003eCDC\u003c\/strong\u003e, \u003cstrong\u003eNIH\u003c\/strong\u003e, and leading universities, supporting ongoing research and advances in laboratory medicine.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":58618173882749,"sku":"SB-642-F","price":320.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/SalivaandBloodSpotHormoneTestKit.webp?v=1785073903","url":"https:\/\/hormonelab.co.uk\/fr\/products\/female-cardiometabolic-thyroid-test-kit","provider":"Hormone Lab UK","version":"1.0","type":"link"}