{"product_id":"male-cardiometabolic-thyroid-test-kit","title":"Male CardioMetabolic \u0026 Thyroid Test Kit | Specialist Doctor Report Included","description":"\u003cp\u003e\u003cstrong\u003eTest ID: SB-642 | Saliva 4-Point Cortisol + Blood Spot Thyroid \u0026amp; CardioMetabolic Panel\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe \u003cstrong\u003eMale CardioMetabolic \u0026amp; Thyroid Test Kit\u003c\/strong\u003e is the most comprehensive at-home multi-system hormone test available for men, measuring \u003cstrong\u003e13 key markers\u003c\/strong\u003e across thyroid function, stress hormone rhythm, blood sugar regulation, inflammation, and cardiovascular health. It combines a \u003cstrong\u003e4-point saliva cortisol profile\u003c\/strong\u003e with a \u003cstrong\u003efull blood spot thyroid and cardiometabolic panel\u003c\/strong\u003e — delivering a clinically complete picture of the interconnected systems most responsible for energy, body composition, cardiovascular risk, and hormonal health in men.\u003c\/p\u003e\n\u003cp\u003eIn men, thyroid function, cortisol, blood sugar, and cardiovascular risk are not separate concerns — they are components of a single integrated metabolic system that also determines testosterone availability and long-term vitality. Chronic dysregulation across these systems is among the most common and most underdiagnosed drivers of premature hormonal decline, metabolic disease, and cardiovascular risk in men. This test is designed to assess all of them together, providing the complete picture that standard GP blood panels fail to deliver.\u003c\/p\u003e\n\u003cp\u003eTest from home with confidence — no clinic visit required. Results within \u003cstrong\u003e3–5 working days\u003c\/strong\u003e.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003eWhy This Test Is Particularly Important for Men\u003c\/h2\u003e\n\u003cp\u003eMen face a distinct and frequently underrecognised pattern of metabolic and thyroid risk that is directly compounded by the cortisol–testosterone relationship: \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eThyroid dysfunction in men is systematically underdiagnosed\u003c\/strong\u003e — men are less likely to be tested for thyroid disease despite carrying significant burden; hypothyroidism in men directly suppresses testosterone production, impairs Leydig cell function, and is a major overlooked cause of low libido, erectile dysfunction, and andropause symptoms\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCortisol suppresses T3 conversion and testosterone simultaneously\u003c\/strong\u003e — through shared precursor competition (pregnenolone steal) and HPA axis dysregulation, chronic stress depletes both active thyroid hormone and testosterone, while TSH and total testosterone can remain within normal ranges\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInsulin resistance is the metabolic hub in men\u003c\/strong\u003e — elevated insulin drives visceral fat accumulation, which increases aromatase activity, converting testosterone to oestrogen; this simultaneously raises cardiovascular risk, worsens insulin resistance, and reduces the testosterone available for energy, performance, and sexual health\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMen’s cardiovascular risk is driven by hormone-metabolic interactions\u003c\/strong\u003e — low testosterone, high cortisol, insulin resistance, and hypothyroidism each independently raise LDL, triglycerides, and hsCRP; their combination in chronically stressed or hormonally declining men creates a compounding cardiovascular risk profile that is rarely assessed in its entirety\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ehsCRP reveals the inflammatory root\u003c\/strong\u003e — elevated C-reactive protein connects thyroid autoimmunity, insulin resistance, visceral fat, and cortisol dysregulation in a single underlying inflammatory process; in men, elevated hsCRP is one of the strongest independent predictors of cardiovascular events and metabolic disease progression\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eWhat This Test Measures\u003c\/h2\u003e\n\u003ch3\u003eBlood Spot — Full Thyroid Panel\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTSH (Thyroid Stimulating Hormone):\u003c\/strong\u003e The standard thyroid screen — but in men, TSH alone misses early thyroid dysfunction, cortisol-driven T3 suppression, and autoimmune thyroid disease. A normal TSH does not rule out clinically significant thyroid impairment in men with symptoms.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFree T3 (FT3):\u003c\/strong\u003e The active thyroid hormone that drives metabolism, energy production, body temperature, testosterone synthesis support, and cognitive function in men. Low FT3 with normal TSH is the hallmark of cortisol-driven thyroid suppression — the most commonly missed pattern in men under chronic stress or sustained high workload.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFree T4 (FT4):\u003c\/strong\u003e The thyroid’s primary output hormone, converted to active T3 in peripheral tissues. Low FT4 with normal TSH indicates early thyroid insufficiency or impaired conversion, often preceding symptomatic hypothyroidism by years.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTotal T4 (TT4):\u003c\/strong\u003e Measures total circulating T4 including the bound fraction. Provides important context for interpreting FT4 and assessing overall thyroid output in men on testosterone therapy, which can affect thyroid hormone binding.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTPO Antibodies (Anti-TPO):\u003c\/strong\u003e The primary diagnostic marker for Hashimoto’s thyroiditis. In men, elevated TPO antibodies are frequently present for years before TSH becomes abnormal, and are associated with progressive thyroid decline, fatigue, and metabolic deterioration.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThyroglobulin Antibodies (Anti-Tg):\u003c\/strong\u003e A second autoimmune marker essential for complete Hashimoto’s screening. Some men have elevated Tg antibodies with normal TPO — making both markers necessary for accurate autoimmune thyroid assessment.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eBlood Spot — CardioMetabolic Panel\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFasting Insulin:\u003c\/strong\u003e The earliest detectable marker of insulin resistance in men — elevated years before HbA1c or fasting glucose becomes abnormal. Elevated insulin drives visceral fat, increases aromatase activity (converting testosterone to oestrogen), and independently raises cardiovascular risk.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHbA1c (Glycated Haemoglobin):\u003c\/strong\u003e Reflects average blood sugar regulation over the preceding 8–12 weeks. Men with low testosterone and high cortisol have significantly elevated risk of pre-diabetes and type 2 diabetes; HbA1c provides the medium-term blood sugar picture that a single fasting glucose cannot.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHDL Cholesterol:\u003c\/strong\u003e The protective cholesterol fraction. Low HDL in men is strongly associated with insulin resistance, visceral fat, and low testosterone; it is one of the most reliable markers of metabolic syndrome in men.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTriglycerides:\u003c\/strong\u003e Elevated triglycerides are a hallmark of insulin resistance and cortisol-driven metabolic dysfunction in men; a primary cardiovascular risk marker that often rises before LDL changes and is directly worsened by high cortisol and low testosterone.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTotal Cholesterol:\u003c\/strong\u003e Provides the overall lipid context; rising total cholesterol in men with hypothyroidism and low testosterone is a well-established pattern requiring integrated assessment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ehsCRP (High-Sensitivity C-Reactive Protein):\u003c\/strong\u003e The gold standard systemic inflammation marker. Elevated hsCRP in men is associated with thyroid autoimmunity, insulin resistance, visceral fat, and testosterone decline — and is one of the strongest independent predictors of cardiovascular events and metabolic disease in men.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSaliva — 4-Point Cortisol Profile\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMorning Cortisol:\u003c\/strong\u003e The Cortisol Awakening Response — critical for activating metabolism, setting testosterone availability, and establishing cognitive performance for the day. A blunted response signals adrenal burnout and impaired recovery; an exaggerated response indicates high stress reactivity and morning testosterone suppression.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNoon Cortisol:\u003c\/strong\u003e Elevated noon cortisol in men promotes insulin resistance, visceral fat accumulation, and aromatase-driven testosterone-to-oestrogen conversion — a compounding driver of both metabolic and hormonal decline.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvening Cortisol:\u003c\/strong\u003e Should be declining significantly to allow testosterone and growth hormone to begin rising during early sleep cycles. Elevated evening cortisol directly suppresses overnight hormonal recovery in men.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNight Cortisol:\u003c\/strong\u003e Elevated night cortisol suppresses the deep sleep phases during which the majority of daily testosterone is produced and thyroid hormone cellular uptake occurs — a primary driver of low morning testosterone, poor recovery, and persistent fatigue in men.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cp\u003eThis test is particularly relevant for men who experience:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePersistent fatigue or exhaustion that does not improve with rest or sleep\u003c\/li\u003e\n\u003cli\u003eUnexplained weight gain or difficulty losing body fat despite training and diet\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor concentration, or reduced cognitive sharpness\u003c\/li\u003e\n\u003cli\u003eLow mood, reduced motivation, or mild depression\u003c\/li\u003e\n\u003cli\u003eFeeling cold all the time, or intolerance to cold temperatures\u003c\/li\u003e\n\u003cli\u003eDry skin, hair thinning or loss, or slow wound healing\u003c\/li\u003e\n\u003cli\u003eLow libido or reduced sexual interest\u003c\/li\u003e\n\u003cli\u003eErectile dysfunction or reduced performance\u003c\/li\u003e\n\u003cli\u003ePoor recovery from exercise or overtraining\u003c\/li\u003e\n\u003cli\u003eElevated cholesterol or triglycerides on previous testing\u003c\/li\u003e\n\u003cli\u003eBlood sugar irregularities, sugar cravings, or energy crashes\u003c\/li\u003e\n\u003cli\u003eChronic stress, burnout, or sustained high workload\u003c\/li\u003e\n\u003cli\u003eInsomnia, night waking, or unrefreshing sleep\u003c\/li\u003e\n\u003cli\u003eSymptoms of low testosterone with inconclusive blood results\u003c\/li\u003e\n\u003cli\u003eCurrently on TRT and wanting a complete metabolic and thyroid picture\u003c\/li\u003e\n\u003cli\u003eFamily history of thyroid disease, diabetes, or heart disease\u003c\/li\u003e\n\u003cli\u003eMen over 40 wanting a comprehensive metabolic and hormonal health baseline\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eKey Features\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e13-marker thyroid, cortisol, and cardiometabolic panel in a single at-home kit\u003c\/li\u003e\n\u003cli\u003eBlood spot collection — simple finger-prick, no clinic visit or venepuncture\u003c\/li\u003e\n\u003cli\u003eSaliva collection for cortisol — non-invasive, captures bioavailable (active) cortisol at four time points\u003c\/li\u003e\n\u003cli\u003eResults within \u003cstrong\u003e3–5 working days\u003c\/strong\u003e after lab receipt\u003c\/li\u003e\n\u003cli\u003eExpert analysis by a \u003cstrong\u003eHormone Specialist PhD Doctor\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003eClear graphical and numerical results with personalised commentary\u003c\/li\u003e\n\u003cli\u003eAll-inclusive price — laboratory fees included, no hidden costs\u003c\/li\u003e\n\u003cli\u003eValid for 12 months from purchase\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrder the kit online\u003c\/strong\u003e — delivered directly to your door.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCollect your blood spot sample\u003c\/strong\u003e via a simple finger-prick onto the collection card, and your \u003cstrong\u003esaliva samples\u003c\/strong\u003e at four time points across the day. Morning saliva collection should be completed before 9am for optimal cortisol accuracy.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePost your samples to the lab\u003c\/strong\u003e using the return instructions included in your kit.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReceive your results within 3–5 working days\u003c\/strong\u003e, with specialist commentary and clear next-step guidance.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003chr\u003e\n\u003ch2\u003eWhat Your Report Includes\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll 13 marker results with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eVisual charts for your cortisol daily curve, thyroid panel, and cardiometabolic markers\u003c\/li\u003e\n\u003cli\u003eClinical interpretation of how your thyroid, cortisol, testosterone, and metabolic results interact\u003c\/li\u003e\n\u003cli\u003eSpecialist commentary by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eWhat does this test measure?\u003c\/h3\u003e\n\u003cp\u003eTSH, Free T3, Free T4, Total T4, TPO Antibodies, Thyroglobulin Antibodies, Fasting Insulin, HbA1c, HDL Cholesterol, Triglycerides, Total Cholesterol, hsCRP (blood spot) plus 4-point Cortisol (saliva) — 13 markers in total.\u003c\/p\u003e\n\u003ch3\u003eWhy test thyroid, cortisol, and cardiometabolic markers together?\u003c\/h3\u003e\n\u003cp\u003eIn men, these systems converge on testosterone and metabolic health. Cortisol suppresses T3 conversion and testosterone simultaneously; insulin resistance drives visceral fat and oestrogen conversion; thyroid insufficiency raises cardiovascular risk and impairs testosterone synthesis. Testing all together identifies the root cause and the full extent of metabolic and hormonal dysfunction in a single kit.\u003c\/p\u003e\n\u003ch3\u003eCan I use this test if I am on TRT or levothyroxine?\u003c\/h3\u003e\n\u003cp\u003eYes. This test is particularly valuable for men on TRT who want to understand whether cortisol dysregulation, thyroid suppression, or metabolic dysfunction is limiting the effectiveness of testosterone therapy. TRT can affect thyroid hormone binding, making FT3 and FT4 measurements especially important alongside TSH.\u003c\/p\u003e\n\u003ch3\u003eHow accurate is the test?\u003c\/h3\u003e\n\u003cp\u003eBlood spot samples are analysed using advanced immunoassay technology; saliva cortisol is measured using \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e — the gold standard for bioavailable hormone measurement.\u003c\/p\u003e\n\u003ch3\u003eWhen will I get my results?\u003c\/h3\u003e\n\u003cp\u003eWithin \u003cstrong\u003e3–5 working days\u003c\/strong\u003e after your samples reach the laboratory.\u003c\/p\u003e\n\u003ch3\u003eAre there hidden costs?\u003c\/h3\u003e\n\u003cp\u003eNo. Laboratory analysis and specialist review are fully included. You are responsible for postage to the lab.\u003c\/p\u003e\n\u003ch3\u003eHow long is the kit valid?\u003c\/h3\u003e\n\u003cp\u003e12 months from purchase.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003eWhy We Partner with ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAt Hormone Lab UK, every home test kit is analysed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e, a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic and research laboratory specialising in hormone testing, thyroid testing, fertility testing, adrenal function, neurotransmitter analysis, cardiometabolic health, heavy metals, and wellness testing. Founded in 1998 by renowned biochemist and breast cancer researcher \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e, ZRT has become one of the world’s leading laboratories for advanced functional health testing.\u003c\/p\u003e\n\u003cp\u003eWith \u003cstrong\u003emore than 11 million laboratory tests\u003c\/strong\u003e performed and healthcare professionals in \u003cstrong\u003eover 96 countries\u003c\/strong\u003e relying on its expertise, ZRT is recognised for scientific excellence, analytical accuracy, and continuous innovation. The laboratory pioneered \u003cstrong\u003eat-home saliva hormone testing\u003c\/strong\u003e, introduced the \u003cstrong\u003efirst commercially available dried blood spot (DBS) hormone tests\u003c\/strong\u003e, and developed \u003cstrong\u003eDried Urine Testing (DUTS)\u003c\/strong\u003e, helping make advanced laboratory diagnostics more accessible and clinically meaningful.\u003c\/p\u003e\n\u003cp\u003eEvery sample is analysed using state-of-the-art \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e and \u003cstrong\u003eICP-MS\u003c\/strong\u003e technology under rigorous quality control standards. ZRT collaborates with the \u003cstrong\u003eCDC\u003c\/strong\u003e, \u003cstrong\u003eNIH\u003c\/strong\u003e, and leading universities, supporting ongoing research and advances in laboratory medicine.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":57961782804861,"sku":null,"price":329.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/SalivaandBloodSpotHormoneTestKit.webp?v=1785073903","url":"https:\/\/hormonelab.co.uk\/fi\/products\/male-cardiometabolic-thyroid-test-kit","provider":"Hormone Lab UK","version":"1.0","type":"link"}