{"product_id":"male-adrenal-function-saliva-test-kit","title":"Male Adrenal Function Saliva Test Kit (LCMS) | Specialist Doctor Report Included","description":"\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eTest ID: S-121\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eThe \u003cstrong\u003eMale Adrenal Function Saliva Test Kit (LCMS)\u003c\/strong\u003e provides a complete at-home assessment of adrenal function and stress hormones specifically designed for men. This test measures \u003cstrong\u003efive key hormones\u003c\/strong\u003e — \u003cstrong\u003eDHEAS\u003c\/strong\u003e and \u003cstrong\u003eCortisol at four points throughout the day\u003c\/strong\u003e (morning, noon, evening, and night) — to reveal how your adrenal glands are managing stress, energy, and the critical relationship between cortisol and testosterone across the full day.\u003c\/p\u003e\n\u003cp\u003eFor men, adrenal function is not simply about stress management — it is a direct determinant of testosterone levels, muscle mass, body composition, sexual health, and cognitive performance. Chronically dysregulated cortisol and depleted DHEAS are among the most common and most underdiagnosed drivers of hormonal decline in men. This test gives you the evidence to understand exactly what is happening and why.\u003c\/p\u003e\n\u003cp\u003eTest from home with confidence — no clinic visit required.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003eWhy Adrenal Function Is a Critical Issue for Men\u003c\/h2\u003e\n\u003cp\u003eThe adrenal glands produce cortisol and DHEAS — hormones that regulate stress, energy, immunity, and inflammation. In men, these hormones are also in a direct biological relationship with testosterone:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCortisol directly suppresses testosterone\u003c\/strong\u003e — both share the same hormonal precursor (pregnenolone); under chronic stress, the body prioritises cortisol at the expense of testosterone through “pregnenolone steal”\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDHEAS is the primary adrenal precursor to testosterone\u003c\/strong\u003e — declining DHEAS (which begins from the late 20s and accelerates under chronic stress) directly reduces testosterone availability, libido, muscle mass, and stress resilience\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigh cortisol promotes visceral fat and aromatisation\u003c\/strong\u003e — elevated cortisol drives abdominal fat accumulation, which increases aromatase activity and converts testosterone to oestrogen, compounding hormonal decline\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCortisol disrupts sleep-based testosterone synthesis\u003c\/strong\u003e — elevated evening and night cortisol suppresses the deep sleep phases during which 70% of daily testosterone is produced\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdrenal burnout leads to hormonal collapse\u003c\/strong\u003e — when the adrenals are depleted, both cortisol and DHEAS fall, causing total exhaustion, loss of drive, and andropause-like symptoms even in younger men\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eWhat This Test Measures\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDHEAS (DS):\u003c\/strong\u003e The primary adrenal precursor to testosterone in men. Low DHEAS is associated with persistent fatigue, low libido, muscle loss, poor stress resilience, reduced testosterone effectiveness, and andropause symptoms. DHEAS declines naturally from the late 20s but can fall dramatically under chronic stress, overtraining, or burnout.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMorning Cortisol:\u003c\/strong\u003e Evaluates the Cortisol Awakening Response — the critical morning surge that sets testosterone balance, energy, and drive for the day. In men, too high suppresses morning testosterone; too low signals adrenal burnout and impaired recovery.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNoon Cortisol:\u003c\/strong\u003e Measures mid-day stress response. Chronically elevated noon cortisol in men promotes insulin resistance, visceral fat, and oestrogen conversion — compounding testosterone decline across the afternoon.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvening Cortisol:\u003c\/strong\u003e Assesses the wind-down phase. Cortisol should be declining significantly by early evening to allow testosterone and growth hormone to rise during the first sleep cycles.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNight Cortisol:\u003c\/strong\u003e Monitors cortisol before sleep. Elevated night cortisol directly suppresses the deep sleep testosterone synthesis that accounts for the majority of daily testosterone production in men.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003eHow and When to Collect Your Saliva Samples: \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/saliva-testing-instructions.pdf?v=1648122023\" title=\"Saliva Testing Instructions\"\u003e\u003cstrong\u003e\u003cem\u003eSaliva Testing Instructions\u003c\/em\u003e\u003c\/strong\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eClick to see the sample \u0026gt;\u0026gt; \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/adrenal-stress-profile_ecda3c08-aa92-475a-a76b-5931c70bde0f.pdf?v=1702933495\" title=\"Adrenal Stress Test Result\"\u003e\u003cstrong\u003eAdrenal Stress Test Result Report\u003c\/strong\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cp\u003eThis test is particularly relevant for men who experience:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePersistent fatigue or exhaustion that sleep does not resolve\u003c\/li\u003e\n\u003cli\u003eDifficulty waking in the morning or feeling unrefreshed\u003c\/li\u003e\n\u003cli\u003eInsomnia, night waking, or inability to switch off at bedtime\u003c\/li\u003e\n\u003cli\u003eLow libido or reduced sexual interest\u003c\/li\u003e\n\u003cli\u003eErectile dysfunction or reduced sexual performance\u003c\/li\u003e\n\u003cli\u003eLoss of muscle mass or poor recovery after training\u003c\/li\u003e\n\u003cli\u003eUnexplained abdominal fat gain despite exercise\u003c\/li\u003e\n\u003cli\u003eAnxiety, irritability, or low mood\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor focus, or reduced motivation\u003c\/li\u003e\n\u003cli\u003eSymptoms of low testosterone with inconclusive blood results\u003c\/li\u003e\n\u003cli\u003eChronic stress, overtraining, or burnout\u003c\/li\u003e\n\u003cli\u003eCurrently on TRT and wanting a full hormonal picture\u003c\/li\u003e\n\u003cli\u003eSugar or salt cravings, especially in the afternoon\u003c\/li\u003e\n\u003cli\u003eLow blood pressure or dizziness on standing\u003c\/li\u003e\n\u003cli\u003eFrequent illness or slow recovery\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eKey Features\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAt-home saliva collection — no needles, no clinic visits\u003c\/li\u003e\n\u003cli\u003eFull-day cortisol profile plus DHEAS — five hormones in a single test\u003c\/li\u003e\n\u003cli\u003eFast results within \u003cstrong\u003e3–5 working days\u003c\/strong\u003e after lab receipt\u003c\/li\u003e\n\u003cli\u003eExpert analysis and guidance by a \u003cstrong\u003eHormone Specialist PhD Doctor\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003eVisual charts, hormone levels, and personalised insights in your report\u003c\/li\u003e\n\u003cli\u003eAll-inclusive price — laboratory fees included, no hidden costs\u003c\/li\u003e\n\u003cli\u003eValid for 12 months from purchase\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrder the kit online\u003c\/strong\u003e — delivered directly to your door.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCollect saliva samples\u003c\/strong\u003e at four times — morning (within 30 minutes of waking, ideally 6–8am), noon, evening, and night — following the detailed instructions provided.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePost your samples to the lab\u003c\/strong\u003e using the return instructions included in your kit.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReceive your results within 3–5 working days\u003c\/strong\u003e with specialist commentary and clear next-step guidance.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003chr\u003e\n\u003ch2\u003eWhat Your Report Includes\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eDHEAS level and all four cortisol readings with reference ranges\u003c\/li\u003e\n\u003cli\u003eVisual charts showing your full daily cortisol curve and DHEAS status\u003c\/li\u003e\n\u003cli\u003eExplanation of what your results mean for testosterone, adrenal health, and physical performance\u003c\/li\u003e\n\u003cli\u003eSpecialist commentary by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eWhat does this test measure?\u003c\/h3\u003e\n\u003cp\u003eDHEAS and Cortisol at four points throughout the day (morning, noon, evening, night) — providing a complete picture of your adrenal stress response, DHEAS status, and their impact on testosterone.\u003c\/p\u003e\n\u003ch3\u003eWhy is this test particularly important for men?\u003c\/h3\u003e\n\u003cp\u003eCortisol and DHEAS are direct regulators of testosterone. Chronic cortisol elevation suppresses testosterone through pregnenolone steal, promotes oestrogen conversion via visceral fat, and blocks sleep-based testosterone synthesis. DHEAS is the adrenal testosterone precursor — its decline is one of the most underrecognised causes of andropause symptoms in men.\u003c\/p\u003e\n\u003ch3\u003eCan I use this test if I am on TRT?\u003c\/h3\u003e\n\u003cp\u003eYes. This test is suitable for men on testosterone replacement therapy and provides valuable insight into whether cortisol dysregulation is undermining the effectiveness of TRT.\u003c\/p\u003e\n\u003ch3\u003eWhy use saliva instead of blood?\u003c\/h3\u003e\n\u003cp\u003eSaliva testing measures bioavailable (active) hormones — the fraction actually affecting your cells — and avoids the cortisol spike triggered by a blood draw, which can distort results.\u003c\/p\u003e\n\u003ch3\u003eHow accurate is the test?\u003c\/h3\u003e\n\u003cp\u003eSamples are analysed using advanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for precise hormone measurement.\u003c\/p\u003e\n\u003ch3\u003eWhen will I get my results?\u003c\/h3\u003e\n\u003cp\u003eWithin \u003cstrong\u003e3–5 working days\u003c\/strong\u003e after your sample reaches the laboratory.\u003c\/p\u003e\n\u003ch3\u003eHow long is the kit valid?\u003c\/h3\u003e\n\u003cp\u003e12 months from purchase.\u003c\/p\u003e\n\u003ch3\u003eWho pays for shipping to the lab?\u003c\/h3\u003e\n\u003cp\u003eYou are responsible for posting your samples to the laboratory. Clear instructions are included in your kit.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003eWhy We Partner with ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAt Hormone Lab UK, every home test kit is analysed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e, a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic and research laboratory specialising in hormone testing, thyroid testing, fertility testing, adrenal function, neurotransmitter analysis, cardiometabolic health, heavy metals, and wellness testing. Founded in 1998 by renowned biochemist and breast cancer researcher \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e, ZRT has become one of the world’s leading laboratories for advanced functional health testing.\u003c\/p\u003e\n\u003cp\u003eWith \u003cstrong\u003emore than 11 million laboratory tests\u003c\/strong\u003e performed and healthcare professionals in \u003cstrong\u003eover 96 countries\u003c\/strong\u003e relying on its expertise, ZRT is recognised for scientific excellence, analytical accuracy, and continuous innovation. The laboratory pioneered \u003cstrong\u003eat-home saliva hormone testing\u003c\/strong\u003e, introduced the \u003cstrong\u003efirst commercially available dried blood spot (DBS) hormone tests\u003c\/strong\u003e, and developed \u003cstrong\u003eDried Urine Testing (DUTS)\u003c\/strong\u003e, helping make advanced laboratory diagnostics more accessible and clinically meaningful.\u003c\/p\u003e\n\u003cp\u003eEvery sample is analysed using state-of-the-art \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e and \u003cstrong\u003eICP-MS\u003c\/strong\u003e technology under rigorous quality control standards. ZRT collaborates with the \u003cstrong\u003eCDC\u003c\/strong\u003e, \u003cstrong\u003eNIH\u003c\/strong\u003e, and leading universities, supporting ongoing research and advances in laboratory medicine.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eHow to use:\u003c\/strong\u003e\u003c\/span\u003e\u003cbr\u003e\u003cimg alt=\"how to collect saliva sample\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/colllect_saliva_test.PNG?v=1497950420\"\u003e\u003c\/p\u003e","brand":"ZRT","offers":[{"title":"Default Title","offer_id":32918206793,"sku":"100","price":161.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Saliva_Hormone_Panel_Test.png?v=1785073869","url":"https:\/\/hormonelab.co.uk\/fi\/products\/male-adrenal-function-saliva-test-kit","provider":"Hormone Lab UK","version":"1.0","type":"link"}