{"product_id":"male-hormonal-acne-test-lcms","title":"Male Hormonal Acne Test (LCMS) | Specialist Doctor Report Included","description":"\u003cp\u003e\u003cstrong\u003eTest ID: S-124\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe \u003cstrong\u003eMale Hormonal Acne Test (LCMS)\u003c\/strong\u003e is a specialist at-home saliva test designed for men, measuring the four key hormones most directly responsible for hormonal acne in the male body — \u003cstrong\u003eOestradiol (E2), Testosterone (T), Progesterone (Pg), and DHEAS (DS)\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003eHormonal acne in men is consistently undertreated because it is rarely recognised for what it is — a visible symptom of androgen excess or hormonal imbalance. Treating it with skincare or antibiotics alone addresses the symptom while leaving the root cause unresolved. This test identifies precisely which hormones are driving your acne and how they are interacting, providing the clinical foundation for effective, targeted treatment.\u003c\/p\u003e\n\u003cp\u003eTest from home with confidence — no clinic visit required.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003eWhy Hormonal Acne in Men Happens\u003c\/h2\u003e\n\u003cp\u003eMale hormonal acne is driven primarily by androgen activity at the sebaceous glands — but the picture is more complex than simply “high testosterone”:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eExcess androgens stimulate sebum overproduction\u003c\/strong\u003e — testosterone and DHEAS bind to receptors in the skin’s oil glands, triggering excess sebum that clogs pores and creates the conditions for bacterial overgrowth and inflammation\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOestradiol imbalance worsens acne in men\u003c\/strong\u003e — men convert testosterone to oestradiol via aromatase; too little oestradiol and androgen activity is unchecked at the skin; too much oestradiol (from visceral fat, alcohol, or oestrogen exposure) can also disrupt the androgen–oestrogen balance and drive breakouts\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDHEAS drives adrenal acne independently of testosterone\u003c\/strong\u003e — elevated DHEAS from chronic stress or adrenal overactivity increases androgen load at the skin even when testosterone appears normal; this explains why acne often worsens dramatically under stress\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProgesterone deficiency allows androgens to dominate\u003c\/strong\u003e — progesterone in men acts as a natural inhibitor of 5-alpha reductase, the enzyme that converts testosterone to the highly potent DHT; low progesterone means more DHT reaches the skin, amplifying sebum production and acne severity\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHormonal acne in men concentrates on the face, back, chest, and shoulders\u003c\/strong\u003e — the androgen-sensitive zones with the highest density of sebaceous glands; severe back and chest acne is a particularly strong indicator of androgen excess\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eWhat This Test Measures\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOestradiol (E2):\u003c\/strong\u003e In men, oestradiol is produced by the conversion of testosterone via aromatase — a process that increases with visceral fat, alcohol consumption, and ageing. Low oestradiol in men is associated with poor bone health and cardiovascular risk; elevated oestradiol suppresses testosterone, drives fat accumulation, and disrupts the androgen balance that controls sebum production. Testing oestradiol alongside testosterone reveals the full androgenic picture.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTestosterone (T):\u003c\/strong\u003e The primary androgen in men and the most direct driver of sebaceous gland activity. Even testosterone within the “normal” range can drive acne if oestradiol is low, progesterone is insufficient to inhibit DHT conversion, or if androgen receptor sensitivity is high. Elevated testosterone — whether endogenous or from testosterone supplementation — is the most common single cause of severe acne in men.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProgesterone (Pg):\u003c\/strong\u003e Present in men in small but important amounts, progesterone acts as a natural 5-alpha reductase inhibitor — blocking the conversion of testosterone to DHT, the highly potent androgen responsible for sebaceous gland overstimulation. Low progesterone in men allows DHT production to increase unchecked, significantly amplifying the androgenic drive to acne. Progesterone also has anti-inflammatory effects on the skin.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDHEAS (DS):\u003c\/strong\u003e An adrenal androgen precursor to testosterone. Elevated DHEAS — driven by chronic stress, adrenal overactivity, or overtraining — raises the total androgen load on the skin independently of testicular testosterone output. DHEAS elevation is frequently the missing piece when men have acne with “normal” testosterone levels. It is particularly relevant for men whose acne worsens under stress or during intense training periods.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBy measuring all four hormones together, this test identifies the specific pattern driving your acne — whether it is androgen excess, oestradiol imbalance, low progesterone, adrenal-driven DHEAS elevation, or a combination.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eClick to see \u0026gt;\u0026gt; \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/saliva-profile-iii-w-history.pdf?v=1702933764\"\u003e\u003cstrong\u003eSaliva Sample Test Result Report\u003c\/strong\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cp\u003eThis test is particularly relevant for men who experience:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePersistent acne on the face, back, chest, or shoulders beyond teenage years\u003c\/li\u003e\n\u003cli\u003eAcne that worsens during periods of high stress or intense training\u003c\/li\u003e\n\u003cli\u003eSevere back or chest acne (a strong indicator of androgen excess)\u003c\/li\u003e\n\u003cli\u003eAcne that appeared or worsened after starting testosterone supplementation or anabolic steroids\u003c\/li\u003e\n\u003cli\u003eAcne alongside other signs of androgen excess: oily skin and scalp, hair loss, or aggressive mood\u003c\/li\u003e\n\u003cli\u003eAcne alongside signs of high oestradiol: gynaecomastia, water retention, or reduced libido\u003c\/li\u003e\n\u003cli\u003eAdult acne that has not responded to skincare or antibiotic treatment\u003c\/li\u003e\n\u003cli\u003eWanting to understand the hormonal root cause before or instead of medication\u003c\/li\u003e\n\u003cli\u003eCurrently on TRT and experiencing acne as a side effect\u003c\/li\u003e\n\u003cli\u003eAcne alongside fatigue, low motivation, or mood changes\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eKey Features\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAt-home saliva collection — no needles, no clinic visits\u003c\/li\u003e\n\u003cli\u003eFour-hormone acne panel: Oestradiol (E2), Testosterone (T), Progesterone (Pg), DHEAS (DS)\u003c\/li\u003e\n\u003cli\u003eResults presented in graphical and numerical formats for easy interpretation\u003c\/li\u003e\n\u003cli\u003eSpecialist commentary by a \u003cstrong\u003eHormone Specialist PhD Doctor\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003eFast results within \u003cstrong\u003e3–5 working days\u003c\/strong\u003e after lab receipt\u003c\/li\u003e\n\u003cli\u003eAll-inclusive price — laboratory fees included, no hidden costs\u003c\/li\u003e\n\u003cli\u003eValid for 12 months from purchase\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrder the kit online\u003c\/strong\u003e — delivered directly to your door.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCollect your saliva sample\u003c\/strong\u003e following the detailed instructions provided in the kit.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePost your sample to the lab\u003c\/strong\u003e using the return instructions included.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReceive your results within 3–5 working days\u003c\/strong\u003e with specialist commentary and personalised guidance.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003chr\u003e\n\u003ch2\u003eWhat Your Report Includes\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll four hormone results with male reference ranges\u003c\/li\u003e\n\u003cli\u003eGraphical and numerical hormone data for easy interpretation\u003c\/li\u003e\n\u003cli\u003eExplanation of your specific hormonal pattern and how it relates to your acne\u003c\/li\u003e\n\u003cli\u003eSpecialist commentary by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003ePersonalised treatment and lifestyle guidance\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eWhich hormones are tested?\u003c\/h3\u003e\n\u003cp\u003eOestradiol (E2), Testosterone (T), Progesterone (Pg), and DHEAS (DS).\u003c\/p\u003e\n\u003ch3\u003eWhy saliva instead of blood?\u003c\/h3\u003e\n\u003cp\u003eSaliva measures bioavailable (active) hormones — the fraction actually reaching your skin cells and sebaceous glands. Blood tests measure total hormone levels, which include bound, inactive hormone and can miss the imbalances most relevant to acne.\u003c\/p\u003e\n\u003ch3\u003eCan I use this test if I am on TRT or other testosterone supplementation?\u003c\/h3\u003e\n\u003cp\u003eYes. This test is particularly valuable for men on TRT who are experiencing acne as a side effect, as it reveals whether the issue is testosterone excess, oestradiol elevation from aromatisation, or progesterone insufficiency — each of which requires a different management approach.\u003c\/p\u003e\n\u003ch3\u003eWill a specialist review my report?\u003c\/h3\u003e\n\u003cp\u003eYes. A PhD Hormone Specialist adds personalised commentary to every report.\u003c\/p\u003e\n\u003ch3\u003eHow long do results take?\u003c\/h3\u003e\n\u003cp\u003e3–5 working days after lab receipt.\u003c\/p\u003e\n\u003ch3\u003eAre there extra fees?\u003c\/h3\u003e\n\u003cp\u003eNo. The laboratory fee is fully included. You are responsible for postage to the lab.\u003c\/p\u003e\n\u003ch3\u003eHow long is the kit valid?\u003c\/h3\u003e\n\u003cp\u003e12 months from purchase.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003eWhat’s the Difference Between Each Testing Method?\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cu\u003eEnzyme Immunoassay (EIA)\u003c\/u\u003e\u003c\/strong\u003e — antibody\/antigen-based technology with moderate specificity and sensitivity, low cost, not ideal for complex hormone analysis.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cu\u003eElectrochemiluminescence (ECLIA)\u003c\/u\u003e\u003c\/strong\u003e — improved antibody\/antigen-based method with better specificity and sensitivity, commonly used for serum hormone analysis, but not ideal for topical hormone therapies.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cu\u003eMass Spectrometry (LCMS, GCMS, ICPMS)\u003c\/u\u003e\u003c\/strong\u003e — gold standard for high sensitivity\/specificity, extended linear range, and complex hormone analysis.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow to use:\u003c\/strong\u003e\u003cbr\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/colllect_saliva_test.PNG?v=1497950420\" alt=\"how to collect saliva sample\"\u003e\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003eWhy We Partner with ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAt Hormone Lab UK, every home test kit is analysed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e, a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic and research laboratory specialising in hormone testing, thyroid testing, fertility testing, adrenal function, neurotransmitter analysis, cardiometabolic health, heavy metals, and wellness testing. Founded in 1998 by renowned biochemist and breast cancer researcher \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e, ZRT has become one of the world’s leading laboratories for advanced functional health testing.\u003c\/p\u003e\n\u003cp\u003eWith \u003cstrong\u003emore than 11 million laboratory tests\u003c\/strong\u003e performed and healthcare professionals in \u003cstrong\u003eover 96 countries\u003c\/strong\u003e relying on its expertise, ZRT is recognised for scientific excellence, analytical accuracy, and continuous innovation. The laboratory pioneered \u003cstrong\u003eat-home saliva hormone testing\u003c\/strong\u003e, introduced the \u003cstrong\u003efirst commercially available dried blood spot (DBS) hormone tests\u003c\/strong\u003e, and developed \u003cstrong\u003eDried Urine Testing (DUTS)\u003c\/strong\u003e, helping make advanced laboratory diagnostics more accessible and clinically meaningful.\u003c\/p\u003e\n\u003cp\u003eEvery sample is analysed using state-of-the-art \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e and \u003cstrong\u003eICP-MS\u003c\/strong\u003e technology under rigorous quality control standards. ZRT collaborates with the \u003cstrong\u003eCDC\u003c\/strong\u003e, \u003cstrong\u003eNIH\u003c\/strong\u003e, and leading universities, supporting ongoing research and advances in laboratory medicine.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":57882531529085,"sku":"SAL-ACNE-01","price":215.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Saliva_Hormone_Panel_Test.png?v=1785073869","url":"https:\/\/hormonelab.co.uk\/es\/products\/male-hormonal-acne-test-lcms","provider":"Hormone Lab UK","version":"1.0","type":"link"}