{"product_id":"female-comprehensive-hormone-thyroid-cardiometabolic-profile","title":"Female Elite Hormone, Thyroid \u0026 CardioMetabolic Profile | 24 Markers","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e SB-646 | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Saliva + Blood Spot | \u003cstrong\u003eTechnology:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults Time:\u003c\/strong\u003e 3-5 Working Days After Laboratory Receives Sample | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory - CLIA Certified | \u003cstrong\u003eHormone Specialist Doctor Interpretation:\u003c\/strong\u003e Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\u003ch2\u003eWhat Does This Test Measure?\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eSaliva - 4-Point Cortisol Profile:\u003c\/strong\u003e Morning, Noon, Evening, and Night Cortisol.\u003cbr\u003e\u003cstrong\u003eBlood Spot LCMS - Sex Hormones and SHBG:\u003c\/strong\u003e Estradiol (E2), Estriol (E3), Estrone (E1), Progesterone, Testosterone, DHEAS, Cortisol, SHBG.\u003cbr\u003e\u003cstrong\u003eBlood Spot - Full Thyroid Panel:\u003c\/strong\u003e TSH, Free T3, Free T4, Total T4, TPO Antibodies, Thyroglobulin Antibodies.\u003cbr\u003e\u003cstrong\u003eBlood Spot - CardioMetabolic Panel:\u003c\/strong\u003e Fasting Insulin, HbA1c, HDL Cholesterol, Triglycerides, Total Cholesterol, hsCRP.\u003cbr\u003e24 markers total - the most complete at-home health profile available for women, combining 4-point saliva cortisol, blood spot LCMS sex hormones including SHBG, a full autoimmune thyroid panel, and a six-marker cardiometabolic panel in a single kit.\u003c\/p\u003e\u003ch2\u003eRelated Symptoms\u003c\/h2\u003e\u003cp\u003ePersistent fatigue, unexplained weight gain, PMS, heavy or irregular periods, perimenopausal or menopausal symptoms, PCOS, insomnia, night sweats, anxiety, brain fog, low libido, hair thinning, sugar cravings, elevated cholesterol or triglycerides, chronic stress, burnout, or told hormone or thyroid results are normal but symptoms persist.\u003c\/p\u003e\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003ePersistent fatigue or exhaustion that does not improve with rest or sleep\u003c\/li\u003e\n\u003cli\u003eUnexplained weight gain or difficulty losing weight despite diet and exercise\u003c\/li\u003e\n\u003cli\u003ePMS, heavy, irregular, painful, or absent periods\u003c\/li\u003e\n\u003cli\u003ePerimenopausal or menopausal symptoms: hot flushes, night sweats, vaginal dryness, low mood\u003c\/li\u003e\n\u003cli\u003ePCOS or symptoms associated with insulin resistance or androgen excess\u003c\/li\u003e\n\u003cli\u003eLow libido, poor energy, or reduced motivation\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor concentration, or anxiety\u003c\/li\u003e\n\u003cli\u003eInsomnia, night sweats, or unrefreshing sleep\u003c\/li\u003e\n\u003cli\u003eHair thinning, dry skin, or feeling cold\u003c\/li\u003e\n\u003cli\u003eSugar cravings, energy crashes, or elevated cholesterol or triglycerides on previous testing\u003c\/li\u003e\n\u003cli\u003eChronic stress or burnout\u003c\/li\u003e\n\u003cli\u003eOn HRT, the contraceptive pill, or levothyroxine and wanting comprehensive monitoring\u003c\/li\u003e\n\u003cli\u003eDiagnosed or suspected Hashimoto's thyroiditis, oestrogen dominance, or thyroid disease\u003c\/li\u003e\n\u003cli\u003eTold hormone or thyroid results are normal but symptoms persist (elevated SHBG is frequently the explanation)\u003c\/li\u003e\n\u003cli\u003eWomen seeking the single most comprehensive at-home hormonal, thyroid, and cardiometabolic health assessment available\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eWhy This Test Is Particularly Important for Women\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eSHBG is the bioavailability gatekeeper for every sex hormone in women - elevated SHBG binds and inactivates oestradiol and testosterone regardless of their total production; cortisol, thyroid disease, oestrogen, and insulin independently alter SHBG; a woman with normal oestradiol and testosterone but elevated SHBG has the hormonal symptoms of deficiency - this is only detectable when SHBG is measured alongside sex hormones\u003c\/li\u003e\n\u003cli\u003eThe 4-point cortisol rhythm is the master regulator of all three other systems - elevated cortisol at any time point suppresses progesterone, impairs thyroid T4-to-T3 conversion, elevates SHBG, promotes visceral fat and insulin resistance, raises triglycerides, suppresses HDL, and elevates hsCRP; only four-time-point measurement reveals morning-normal or evening-elevated patterns that a single value cannot detect\u003c\/li\u003e\n\u003cli\u003eThyroid dysfunction in women is systematically under-detected by TSH alone - cortisol-driven T3 suppression produces functional hypothyroidism with normal TSH; Hashimoto's is present for years before TSH becomes abnormal and is directly worsened by cortisol and insulin resistance; oestrogen and SHBG changes alter thyroid hormone binding; all these interactions are only visible when all four systems are assessed simultaneously\u003c\/li\u003e\n\u003cli\u003eFasting insulin is the earliest detectable marker of insulin resistance in women - elevated years before HbA1c or fasting glucose becomes abnormal, directly driven by cortisol, progesterone deficiency, oestrogen decline, and PCOS, and worsening every other system on this panel\u003c\/li\u003e\n\u003cli\u003ehsCRP is the convergence biomarker of all four systems - elevated simultaneously by cortisol dysregulation, progesterone deficiency, Hashimoto's autoimmunity, insulin resistance, and visceral fat; a stronger independent predictor of cardiovascular disease in women than LDL cholesterol\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\u003cp\u003eEmail us at \u003ca href=\"mailto:info@hormonelab.co.uk\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours.\u003c\/p\u003e\u003ch2\u003eHow It Works\u003c\/h2\u003e\u003col\u003e\n\u003cli\u003eOrder your kit - delivered directly to your door\u003c\/li\u003e\n\u003cli\u003eCollect saliva at four time points (morning before 9am, noon, evening, night) for the cortisol panel, and a finger-prick blood spot for the sex hormones, thyroid, and cardiometabolic markers; cycle timing guidance is included\u003c\/li\u003e\n\u003cli\u003ePost your samples to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your full report by email within 3-5 working days\u003c\/li\u003e\n\u003c\/ol\u003e\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eAll 24 marker results with female-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eVisual charts for your 4-point cortisol daily curve, all sex hormones and SHBG, the full thyroid panel, and all six cardiometabolic markers\u003c\/li\u003e\n\u003cli\u003eIntegrated clinical interpretation of how cortisol rhythm, sex hormones, SHBG, thyroid markers, and cardiometabolic results interact as a single female hormonal-metabolic system by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003eSHBG-adjusted sex hormone bioavailability assessment\u003c\/li\u003e\n\u003cli\u003eCortisol-thyroid T3 and Hashimoto's autoimmunity assessment in cortisol, insulin, and SHBG context\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included - no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e - a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003ePioneers of at-home \u003cstrong\u003edried blood spot (DBS)\u003c\/strong\u003e and saliva hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePersonalised reference ranges based on age and sex\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eThrough our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to people across the UK and Europe - from the comfort of home.\u003c\/p\u003e\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eWhy do I need SHBG tested alongside sex hormones?\u003c\/strong\u003e\u003cbr\u003eSHBG binds and inactivates oestradiol and testosterone. A woman with elevated SHBG - from cortisol, thyroid disease, oestrogen excess, or HRT - has full hormonal deficiency symptoms despite normal-range total sex hormone levels. SHBG is essential for interpreting every sex hormone result and for calculating true bioavailable hormone status.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWhy test all four systems together?\u003c\/strong\u003e\u003cbr\u003eIn women these systems form a single integrated regulatory network. Cortisol suppresses progesterone and impairs thyroid T3 conversion; insulin resistance worsens with cortisol elevation and oestrogen decline; SHBG elevation inactivates sex hormones; Hashimoto's is worsened by cortisol and insulin. Testing them together reveals the root cause of symptoms that remain unexplained when each system is assessed in isolation.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCan I use this test if I am on HRT, the contraceptive pill, or levothyroxine?\u003c\/strong\u003e\u003cbr\u003eYes. HRT and the pill profoundly elevate SHBG and affect thyroid hormone binding and lipid profiles - which is precisely why this comprehensive panel provides more clinically meaningful information than standard blood tests for women on hormonal treatment. Follow the timing guidance in your kit.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWhen should I collect my samples during my cycle?\u003c\/strong\u003e\u003cbr\u003eGuidance on optimal cycle timing for both saliva and blood spot samples is included in the kit instructions.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. There are no additional charges. You are only responsible for posting your samples to the laboratory.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":58618417709437,"sku":"SB-646-F","price":559.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Female-Elite-Hormone-Thyroid-and-CardioMetabolic-Profile.webp?v=1792919866","url":"https:\/\/hormonelab.co.uk\/de\/products\/female-comprehensive-hormone-thyroid-cardiometabolic-profile","provider":"Hormone Lab UK","version":"1.0","type":"link"}