{"title":"Dried Urine Spot Tests (DUS)","description":"\u003cp\u003eAdvanced at-home dried urine spot tests for men, women, and children. Collect urine at two or four time points onto a filter paper strip, allow to dry, and post to our accredited laboratory. Results are analysed using LC-MS\/MS and ICP-MS technology by PhD-level scientists and returned within \u003cstrong\u003e3–5 working days\u003c\/strong\u003e — with accuracy comparable to traditional 24-hour urine collections, without the inconvenience.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBiomarkers available:\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003eSleep \u0026amp; Stress:\u003c\/strong\u003e Melatonin, Cortisol, Cortisone, DHEA\u003cbr\u003e\u003cstrong\u003eNeurotransmitters:\u003c\/strong\u003e Serotonin, Dopamine, Norepinephrine, Epinephrine, GABA, Glutamate, Histamine, PEA \u0026amp; key metabolites\u003cbr\u003e\u003cstrong\u003eMenstrual Cycle \u0026amp; Fertility:\u003c\/strong\u003e Oestradiol (E2), Progesterone, LH, FSH — tracked across a full cycle\u003cbr\u003e\u003cstrong\u003eThyroid \u0026amp; Iodine:\u003c\/strong\u003e Iodine, Creatinine, Thyroid Essential Elements\u003cbr\u003e\u003cstrong\u003eHeavy Metals \u0026amp; Elements (ICP-MS):\u003c\/strong\u003e Mercury, Lead, Cadmium, Arsenic, Zinc, Magnesium, Selenium, Copper\u003c\/p\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003ch3\u003e\u003cstrong\u003e\u003ca title=\"Hormone Symptom Check List For Women\" href=\"https:\/\/hormonelab.co.uk\/pages\/symptom-checklist-for-women\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/female_symbol_icon.png?v=1504021588\" alt=\"female symbol\"\u003e Symptom Checklist For Women\u003c\/a\u003e\u003c\/strong\u003e\u003c\/h3\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003ch3\u003e\u003cstrong\u003e\u003ca title=\"Hormone Symptom Check List For Men\" href=\"https:\/\/hormonelab.co.uk\/pages\/symptom-checklist-for-men\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/male_symbol_icon.png?v=1504021658\" alt=\"male symbol\"\u003e Symptom Checklist For Men\u003c\/a\u003e\u003c\/strong\u003e\u003c\/h3\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cstrong\u003e\u003ca title=\"Sample Hormone Test Result Report\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Sample_Hormone_Test_Report.pdf?5141989513353469274\"\u003eSAMPLE HORMONE TEST RESULT REPORT\u003c\/a\u003e\u003c\/strong\u003e\u003c\/p\u003e","products":[{"product_id":"iodine-creatinine-test-kit-icpms","title":"Iodine  and Creatinine Test | ICPMS | 2 Markers","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e U-326 Iodine  and Creatinine Test (I \u0026amp; CRTN) | ICPMS  | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Dried Urine  | \u003cstrong\u003eTechnology:\u003c\/strong\u003e AdvancedICP-MS analysis with specialist laboratory interpretation included | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory (CLIA-certified) | \u003cstrong\u003eTest Result:\u003c\/strong\u003e in 3-5 working days | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eICPMS The Iodine \u0026amp; Creatinine \u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eA specialised testing tool designed to measure the levels of iodine and creatinine in the human body accurately. It provides a convenient and reliable method for assessing these important substances in both males and females. The test is also suitable for children. \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTest Method\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eMass spectrometry (ICPMS) –\u003c\/strong\u003e utilizes different sample preparations to measure analytes, or fragments of analytes, via a mass\/charge ratio. Gold standard for high sensitivity\/specificity, extended linear range, and complex hormone analysis. Slow adoption due to cost of instrumentation and need for highly trained staff.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIodine\u003c\/strong\u003e is an essential mineral that plays a crucial role in maintaining proper thyroid function and overall health. It is necessary for the production of thyroid hormones, which regulate metabolism, growth, and development. This kit’s Iodine spot test component allows individuals to determine their iodine levels quickly and conveniently. By assessing iodine levels, one can gain insights into thyroid health and ensure one meets daily iodine requirements.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCreatinine is a waste product\u003c\/strong\u003e produced by the muscles during normal metabolism. It is primarily eliminated from the body through the kidneys. The Creatinine spot test in this kit allows individuals to assess the levels of creatinine in their urine. This information is valuable in evaluating kidney function, as abnormal creatinine levels may indicate potential kidney problems or conditions.\u003c\/p\u003e\n\u003cp\u003eThe I \u0026amp; CRTN Urine Spot Test Kit provides a user-friendly and non-invasive method for individuals to monitor their iodine and creatinine levels. The kit typically includes all the necessary components, such as testing strips or reagents, as well as clear instructions on how to perform the test accurately.\u003c\/p\u003e\n\u003cp\u003eBy using this test kit regularly, individuals can keep track of their iodine and creatinine levels over time, enabling them to make informed decisions about their diet, lifestyle, and overall well-being. It is important to note that while this test kit provides valuable insights, it should not be considered a substitute for professional medical advice. In case of any concerns or abnormal results, it is advisable to consult with a healthcare professional for further evaluation and guidance.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eIodine Deficiency\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eIodine deficiency or excessive iodine levels can have a negative impact on your health, including the development of goitre, hypothyroidism, acneiform eruption, and reduced mental function. This dry urine test will also help determine the effectiveness of iodine supplementation in an individual and track treatment progress. It is easy to use and only requires urine collection on a filter strip two times a day.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eTest result:\u003c\/strong\u003e\u003c\/span\u003e This kit is safe, and it is easy to verify the level of iodine. Once the laboratory obtains and analyzes your sample (dried urine), you will receive the test result within 3-5 working days. In your test result, you will find the following:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cem\u003eYour Iodine and Creatinine values are in graphical form, making it possible to decipher whether the iodine levels are within the normal range.\u003c\/em\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cem\u003eEasy to understand explanation regarding the functions of the tested Iodine by our laboratory professional.\u003c\/em\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cem\u003eTips and advice on what to do next.\u003c\/em\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eWe strongly recommend that you consult your results with your health care provider, GP, or doctor to know whether or not any further actions need to be carried out and get started with ample treatment if needed.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eWhat is Iodine and what does it do for the human body?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eIodine is a mineral found in some foods. The body needs iodine to make thyroid hormones, which control the body’s metabolism and other important functions. The body also needs thyroid hormones for proper bone and brain development during pregnancy and infancy.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eWho needs iodine the most and how much do I need of it?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eGetting enough iodine is important for everyone, but it is especially critical for infants and women who are pregnant. Each day depends on the person’s age, how much iodine is needed. Average daily recommended amounts are listed below in micrograms (mcg).\u003c\/p\u003e\n\u003ctable style=\"width: 454px;\" border=\"0\" cellspacing=\"0\" cellpadding=\"0\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 233px;\" valign=\"top\"\u003e\n\u003cp align=\"center\"\u003e\u003cstrong\u003eLife Stage\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 225px;\" valign=\"top\"\u003e\n\u003cp align=\"center\"\u003e\u003cstrong\u003eRecommended Amount\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 233px;\" valign=\"top\"\u003e\n\u003cp\u003eBirth to 6 months\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 225px;\" valign=\"top\"\u003e\n\u003cp align=\"right\"\u003e110 mcg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 233px;\" valign=\"top\"\u003e\n\u003cp\u003eInfants 7-12 months\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 225px;\" valign=\"top\"\u003e\n\u003cp align=\"right\"\u003e130 mcg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 233px;\" valign=\"top\"\u003e\n\u003cp\u003eChildren 1-8 years\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 225px;\" valign=\"top\"\u003e\n\u003cp align=\"right\"\u003e90 mcg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 233px;\" valign=\"top\"\u003e\n\u003cp\u003eChildren 9-13 years\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 225px;\" valign=\"top\"\u003e\n\u003cp align=\"right\"\u003e120 mcg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 233px;\" valign=\"top\"\u003e\n\u003cp\u003eTeens 14-18 years\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 225px;\" valign=\"top\"\u003e\n\u003cp align=\"right\"\u003e150 mcg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 233px;\" valign=\"top\"\u003e\n\u003cp\u003eAdults\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 225px;\" valign=\"top\"\u003e\n\u003cp align=\"right\"\u003e150 mcg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 233px;\" valign=\"top\"\u003e\n\u003cp\u003ePregnant teens and women\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 225px;\" valign=\"top\"\u003e\n\u003cp align=\"right\"\u003e220 mcg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 233px;\" valign=\"top\"\u003e\n\u003cp\u003eBreastfeeding teens and women\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 225px;\" valign=\"top\"\u003e\n\u003cp align=\"right\"\u003e290 mcg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eIodine deficiency is a global health problem\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eApproximately 2 billion of the world’s population is iodine deficient. According to the most recent NHANES surveys, urinary iodine levels have dropped in the U.S. by half since the 1970s, and nearly 10% of the population has some degree of iodine deficiency. Iodine deficiency is resurfacing in developed countries like the U.S. and Western Europe as efforts are made to reduce the consumption of iodine-containing salt and foods (eggs and dairy) to lower blood pressure and blood lipids.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eAdequate Iodine is Essential at All Stages of Life\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eIn the developing fetus, an adequate iodine supply from the mother is essential for thyroid hormone production, which is vital for proper neurological development. In those areas of the world with severe iodine deficiency, pregnant women are at increased risk of miscarriage, stillbirths, or giving birth to children with cretinism and severe neurological and developmental defects. Even in areas of the world with mild to moderate iodine deficiency, children born to mothers who are iodine deficient during pregnancy can have impaired intellectual development and are at increased risk for developing attention deficit and hyperactivity disorders.\u003c\/p\u003e\n\u003cp\u003eIn children and adults, iodine deficiency can lead to lower thyroid hormone synthesis and consequent symptoms and conditions of hypothyroidism. When iodine levels drop below a critical threshold, consequent low thyroid hormone levels signal the brain to increase TSH production. Excessive stimulation of the thyroid gland by TSH, caused by iodine deficiency, leads to overgrowth (goitre) in an effort to maintain steady-state thyroid hormone synthesis.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eWhy high Iodine levels can be problematic:\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eHigh iodine levels, resulting from consumption of high iodine-containing foods (e.g., seaweed) or iodine medications or supplements, can also disrupt normal thyroid function, causing goitre and both hyperthyroidism or hypothyroidism.\u003c\/p\u003e\n\u003cp\u003eHyperthyroidism is more likely to occur in the elderly who have been exposed acutely to high iodine after living for years in a low iodine environment. Chronic low iodine can lead to the development of autonomous thyroid nodules that produce excessive amounts of thyroid hormones (hyperthyroidism) when acutely exposed to high levels of iodine. Although rare, hyperthyroidism and associated thyrotoxicosis caused by excessive iodine consumption can cause arrhythmias and precipitate adverse cardiovascular events.\u003c\/p\u003e\n\u003cp\u003eIn some people, acute high iodine exposure can paradoxically suppress thyroid hormone synthesis (Wolff-Chaikoff effect) and lead to goitre and hypothyroidism. Most people with normal thyroid glands escape from the Wolff-Chaikoff effect within about two days. However, a small percentage of people, particularly those with underlying subclinical hypothyroidism or with thyroid glands compromised by autoimmune problems (e.g., Hashimoto’s), are less likely to recover from the suppressive effects of high iodine, and progress to a more severe and permanent hypothyroid state that requires thyroid medication.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eHow does Iodine help prevent Infection:\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eIodine’s effectiveness as an antimicrobial has been known for over a hundred years as it has been used for preoperative surgical skin preparation to prevent infection. As an antimicrobial, it is of relevance that iodine from the bloodstream concentrates in a broad spectrum of tissues that are repeatedly exposed to infectious organisms (e.g., skin, eyes, gastrointestinal tract, salivary gland, nasal and oral mucosa, breast ducts, uterine lining, prostate). Uptake of iodide by these tissues and enzymatic formation of reactive iodine compounds (e.g., hypoiodous acid) would serve the role of a protective antimicrobial, working in concert with the immune system.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eIodine sufficiency is likely different in the Thyroid gland than in other tissues\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eControversy exists as to how much iodine consumption is optimal. Sufficiency for the thyroid (about 150-300 µg daily consumption of iodine) is likely much lower than sufficiency for other tissues that are known to concentrate iodine such as the breast. Studies in humans have shown that for iodine to be protective (prevent benign breast disease such as fibrocystic), a minimum of 3,000 µg and optimally 6,000 µg or more of daily iodine consumption are required, far exceeding the CDC and WHO recommendations of 150-300 µg daily consumption of iodine-containing foods, salts, or supplements.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eDevelopment of a patient-convenient test to measure Iodine levels in dried urine\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eWith iodine playing so many different roles in optimising health and preventing disease in the thyroid and other tissues, it is essential that adequate iodine intake is maintained and problems associated with low or excessive iodine intake are identified and treated appropriately. To this end, ZRT has developed a simple and convenient test to measure an individual’s iodine level in urine dried on a filter strip. This method was developed to circumvent the more cumbersome collection of all urine over a 24 hour period.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eCollecting and testing urinary Iodine\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eIodine is collected twice during the day (first morning and last night void) on filter strips either by dipping the strip in urine collected in a cup, or by urinating directly on the strip. The urine-saturated filter strips are allowed to dry overnight and then sent to the laboratory for iodine and creatinine testing. The iodine content of the dried filter strips is determined following extraction and measurement by inductively coupled plasma mass spectrometry (ICP-MS). Creatinine is measured in the same urine extract by a modification of the Jaffe method. Iodine is measured in µg per litre of urine, and the average of morning and night levels is taken. The creatinine level is used to correct for hydration status of the individual because it is dependent on urine dilution. Results are therefore expressed in µg of iodine per g of creatinine.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eAdvantages of dried urine for Iodine \u0026amp; Creatinine (I\u0026amp;CRTN) testing:\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e• Urine collection and shipment of the dried filter strips are simple and convenient for the patient and practitioner.\u003cbr\u003e• Dual collections of urine directly on a filter strip, upon awakening and just before bed, are far more convenient and less subject to the inherent inaccuracies of a 24 hr urine collection.\u003cbr\u003e• Iodine and creatinine in dried urine are exceptionally stable for weeks at room temperature, allowing more flexibility in the collection, shipment, testing, and storage.\u003cbr\u003e• Iodine results expressed in µg iodine per g creatinine helps to normalise results when problems exist with urine that is very concentrated or dilute.\u003cbr\u003e• Iodine testing allows for the determination of iodine status based on CDC and WHO guidelines for thyroid sufficiency, as well as extra-thyroidal sufficiency.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHandout: \u003ca title=\"Iodine Content in Food\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Iodine_Content_in_Foods_PHO_557a298f-2040-4d63-a5b3-f07381814f07.pdf?v=1646916592\"\u003eIodine Content in Foods\u003c\/a\u003e\u003c\/strong\u003e\u003c\/p\u003e","brand":"ZRT","offers":[{"title":"Default Title","offer_id":32923445769,"sku":"10001","price":139.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Iodine-and-Creatinine-Test.webp?v=1792668787"},{"product_id":"elements-profile-dried-urine","title":"Toxic and Essential Elements Profile | ICPMS | 8 Markers","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e U-327 Toxic and Essential Elements Profile | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Dried Urine (4 collections) | \u003cstrong\u003eTechnology:\u003c\/strong\u003e AdvancedICP-MS analysis with specialist laboratory interpretation included | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory (CLIA-certified) | \u003cstrong\u003eTest Result:\u003c\/strong\u003e in 3-5 working days | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\u003ch2\u003eCould Toxic Elements Be Disrupting Your Thyroid Health?\u003c\/h2\u003e\n\u003cp\u003eHeavy metals and toxic elements are increasingly present in our food, water, and environment — and the thyroid is one of the organs most vulnerable to their effects. Mercury, arsenic, cadmium, and bromine can all interfere with thyroid hormone production, conversion, and uptake, often causing symptoms that are mistaken for other conditions or dismissed entirely.\u003c\/p\u003e\n\u003cp\u003eThis at-home test analyses \u003cstrong\u003e8 key toxic and essential elements in dried urine\u003c\/strong\u003e using \u003cstrong\u003eICP-MS technology\u003c\/strong\u003e — the most sensitive and accurate method available for trace element analysis. It is specifically designed to assess how elements in your environment and diet may be affecting your thyroid function and overall health.\u003c\/p\u003e\n\u003ch2\u003eWhat This Test Measures\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDried Urine — Toxic \u0026amp; Essential Elements (ICP-MS):\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIodine (I)\u003c\/strong\u003e — essential for thyroid hormone production (T3 and T4); deficiency is a leading cause of hypothyroidism and goitre\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBromine (Br)\u003c\/strong\u003e — competes with iodine for thyroid receptor sites; elevated bromine can suppress thyroid function even when iodine appears adequate\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSelenium (Se)\u003c\/strong\u003e — critical for converting inactive T4 into active T3; also protects the thyroid from oxidative damage\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eArsenic (As)\u003c\/strong\u003e — toxic metalloid found in rice, seafood, and contaminated water; disrupts thyroid hormone synthesis and metabolism\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMercury (Hg)\u003c\/strong\u003e — highly toxic; accumulates from contaminated fish and dental amalgam; associated with thyroid dysfunction and autoimmunity\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCadmium (Cd)\u003c\/strong\u003e — found in cigarette smoke and contaminated food; linked to increased risk of thyroid disorders including goitre\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLithium (Li)\u003c\/strong\u003e — trace element that affects thyroid hormone synthesis; elevated levels — from medication or environmental sources — can suppress thyroid output\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCreatinine (Crtn)\u003c\/strong\u003e — used to adjust urine results for concentration, ensuring all element readings are accurate and comparable\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWho Is This Test For?\u003c\/h2\u003e\n\u003cp\u003eThis test is suitable for \u003cstrong\u003eadults and children\u003c\/strong\u003e who:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHave an underactive or overactive thyroid, or suspect thyroid dysfunction\u003c\/li\u003e\n\u003cli\u003eEat fish or seafood regularly, particularly high-mercury species (tuna, swordfish, shark)\u003c\/li\u003e\n\u003cli\u003eHave mercury dental fillings (amalgam)\u003c\/li\u003e\n\u003cli\u003eSmoke or are regularly exposed to cigarette smoke\u003c\/li\u003e\n\u003cli\u003eConsume rice frequently or live in areas with high environmental contamination\u003c\/li\u003e\n\u003cli\u003eExperience fatigue, brain fog, weight changes, hair loss, poor sleep, or cold intolerance\u003c\/li\u003e\n\u003cli\u003eWant to understand whether environmental toxins are contributing to their thyroid symptoms\u003c\/li\u003e\n\u003cli\u003eAre monitoring iodine and selenium levels to support thyroid health\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca class=\"text-link\" href=\"mailto:info@hormonelab.co.uk\" rel=\"nofollow\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours with a suggestion.\u003c\/p\u003e\n\u003ch2\u003eThyroid Symptoms This Test Can Help Investigate\u003c\/h2\u003e\n\u003cp\u003eToxic element imbalances often present as classic thyroid symptoms, including:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePersistent fatigue and low energy\u003c\/li\u003e\n\u003cli\u003eUnexplained weight gain or difficulty losing weight\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor memory, or slow thinking\u003c\/li\u003e\n\u003cli\u003eHair loss, dry skin, or brittle nails\u003c\/li\u003e\n\u003cli\u003eFeeling cold when others do not\u003c\/li\u003e\n\u003cli\u003ePoor sleep or insomnia\u003c\/li\u003e\n\u003cli\u003eLow mood or depression\u003c\/li\u003e\n\u003cli\u003eMenstrual irregularities or fertility concerns\u003c\/li\u003e\n\u003cli\u003eMuscle or joint aches with no clear cause\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrder your kit\u003c\/strong\u003e — delivered directly to your door\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCollect your urine sample at home\u003c\/strong\u003e — using the dried urine spot collection cards included; no clinic visit required\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePost your sample\u003c\/strong\u003e to the laboratory using the instructions and return envelope provided\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReceive your results by email\u003c\/strong\u003e within \u003cstrong\u003e3–5 working days\u003c\/strong\u003e of the lab receiving your sample\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003eWhat You Receive With Your Results\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll 8 markers displayed in clear \u003cstrong\u003egraphics and easy-to-read values\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003eA written interpretation by a \u003cstrong\u003eHormone Specialist PhD Doctor\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003eGuidance on what your results mean and \u003cstrong\u003erecommended next steps\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — \u003cstrong\u003eno hidden charges\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/toxic-essential-elements-urine.pdf?v=1647865876\"\u003e\u003cstrong\u003eView a Sample Test Result Report\u003c\/strong\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePioneers of at-home \u003cstrong\u003edried urine spot\u003c\/strong\u003e element testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eICP-MS\u003c\/strong\u003e technology for clinical-grade trace element accuracy\u003c\/li\u003e\n\u003cli\u003eEach element tested in the most clinically significant sample type\u003c\/li\u003e\n\u003cli\u003ePersonalised reference ranges based on age and sex\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThrough our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed testing to people across the UK and Europe — from the comfort of home.\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eHow are toxic elements linked to thyroid disease?\u003c\/strong\u003e\u003cbr\u003eMercury, cadmium, arsenic, and bromine are all known thyroid disruptors. They can interfere with iodine uptake, block thyroid hormone receptors, trigger autoimmune responses, and impair the conversion of T4 to the active hormone T3. Many people with thyroid symptoms have never had their toxic element levels assessed — this test fills that gap.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is urine used instead of blood for this test?\u003c\/strong\u003e\u003cbr\u003eDried urine is the most clinically appropriate sample for measuring urinary excretion of trace elements. The kidneys filter and excrete iodine, selenium, arsenic, mercury, and cadmium — making urine the most reliable indicator of ongoing exposure and body burden for these elements. Creatinine is measured alongside to correct for urine concentration.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is ICP-MS and why does it matter?\u003c\/strong\u003e\u003cbr\u003eICP-MS (Inductively Coupled Plasma Mass Spectrometry) is the gold standard for trace element analysis. It detects elements at extremely low concentrations with high sensitivity and specificity — far beyond what standard laboratory methods can achieve. This level of precision is essential when measuring toxic elements that may be harmful even at trace levels.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan bromine really affect my thyroid?\u003c\/strong\u003e\u003cbr\u003eYes. Bromine is a halogen that competes directly with iodine for uptake into the thyroid gland. Even if your iodine intake is adequate, elevated bromine — from flame retardants, certain medications, or processed foods — can block iodine absorption and suppress thyroid hormone production. This is rarely tested on the NHS.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIs this test suitable for children?\u003c\/strong\u003e\u003cbr\u003eYes. The test is suitable for adults and children. Urine sample collection is non-invasive and straightforward. If testing a child, please follow the collection instructions carefully.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included in the purchase price. There are no additional charges. You are only responsible for posting your sample to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"ZRT","offers":[{"title":"Default Title","offer_id":32923479881,"sku":"100012","price":179.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Toxic-and-Essential-Elements-Profile.webp?v=1792668394"},{"product_id":"sleep-hormone-test-udh-i","title":"Sleep Hormone Test Kit (UDH I | 16 Markers","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e U-321 Sleep Hormone Test Kit (UDH I) | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Dried Urine (4 collections) | \u003cstrong\u003eTechnology:\u003c\/strong\u003e Advanced LCMS analysis with specialist laboratory interpretation included | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory (CLIA-certified) | \u003cstrong\u003eTest Result:\u003c\/strong\u003e in 3-5 working days | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\u003ch1\u003eSleep Hormone Test Kit (UDH I)\u003c\/h1\u003e\n\u003cp\u003eLCMS Urine Diurnal Hormones Profile (UDH I) Sleep Balance Profile Testing in Dried Urine Spot (DUS) is a diagnostic tool that measures specific hormones and biomarkers related to sleep quality and circadian rhythm. The Sleep Balance Profile Test accurately measures the following 16 hormones:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eMelatonin Metabolite 6 Sulfatoxymelatonin (MT6s4) x 4 times a day\u003c\/li\u003e\n\u003cli\u003eFree Cortisol (FCx4) 4 Times a day\u003c\/li\u003e\n\u003cli\u003eFree Cortisone (FCnx4) 4 Times a day\u003c\/li\u003e\n\u003cli\u003eCreatinine (Crtnx4)4 Times a day\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTest Result:\u003c\/strong\u003e You will receive your test result 3-5 working days after the laboratory receives your sample. You will see your hormone levels in graphics and numbers on your test results. In the comments, you will also see laboratory comments by Hormone Specialist PhD Dr: you will find Dr analysis of your hormone levels and what to do next.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTest Method:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eMass spectrometry (LCMS)–\u003c\/strong\u003e utilizes different sample preparations to measure analytes, or fragments of analytes, via a mass\/charge ratio. Gold standard for high sensitivity\/specificity, extended linear range, and complex hormone analysis. Slow adoption due to cost of instrumentation and need for highly trained staff.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca class=\"text-link\" href=\"mailto:info@hormonelab.co.uk\" rel=\"nofollow\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours with a suggestion.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eKey Features\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSleep Quality Assessment: The Sleep Balance Profile Test provides insights into various aspects of sleep quality, including the measurement of melatonin, a hormone involved in regulating the sleep-wake cycle.\u003c\/li\u003e\n\u003cli\u003eSleep Disorder Identification: The Sleep Balance Profile Test aids in identifying potential underlying causes of sleep disorders such as insomnia, delayed sleep phase syndrome, and circadian rhythm disorders.\u003c\/li\u003e\n\u003cli\u003eHormonal Evaluation: The Sleep Balance Profile Test measures the levels of key hormones involved in sleep regulation, including melatonin, cortisol, and cortisone.\u003c\/li\u003e\n\u003cli\u003eDried Urine Spot (DUS) Collection: The test utilises dried urine spot collection, which offers convenience and ease of use. Dried urine samples can be collected at home.\u003c\/li\u003e\n\u003cli\u003eMelatonin Assessment: Melatonin is a hormone produced by the pineal gland that regulates the sleep-wake cycle. This test evaluates melatonin levels, providing insights into the body’s natural production of this sleep hormone.\u003c\/li\u003e\n\u003cli\u003eCortisol and Cortisone Measurement: Cortisol and cortisone are stress hormones that can impact sleep quality. The test assesses these hormone levels, helping to identify any imbalances that may contribute to sleep disturbances.\u003c\/li\u003e\n\u003cli\u003eCircadian Rhythm Evaluation: The Sleep Balance Profile Test provides information about the body’s circadian rhythm, which is crucial for maintaining a healthy sleep pattern.\u003c\/li\u003e\n\u003cli\u003eComprehensive Sleep Assessment: By examining multiple hormone levels involved in sleep regulation, the Sleep Balance Profile Test offers a comprehensive evaluation of sleep health.\u003c\/li\u003e\n\u003cli\u003eTreatment Monitoring: The Sleep Balance Profile Test can be utilized to monitor the effectiveness of interventions and treatment plans for sleep-related issues.\u003c\/li\u003e\n\u003cli\u003ePersonalised Treatment Approach: The test results can help healthcare professionals develop personalised treatment plans for individuals experiencing sleep disturbances.\u003c\/li\u003e\n\u003cli\u003eClick to see \u003ca title=\"Sleep Balance Sample Report\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Sleep-balance-profile_Sample_Report.pdf?v=1657974970\"\u003e\u003cstrong\u003eSleep Balance Sample Report\u003c\/strong\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eCollect samples from the comfort of your home and post them to our lab.\u003c\/li\u003e\n\u003cli\u003eThe test is suitable for both adults and children.\u003c\/li\u003e\n\u003cli\u003eThe test must be used within 12 months after the purchase date.\u003c\/li\u003e\n\u003cli\u003eThe test kit includes a laboratory fee: no additional laboratory cost or tax.\u003c\/li\u003e\n\u003cli\u003eCustomers are responsible for shipping their samples to the laboratory.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eThe Test Kit pack includes\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTest Requisition Form includes Symptom Checklist\u003c\/li\u003e\n\u003cli\u003eRequisition Form to complete, including your personal and medical history\u003c\/li\u003e\n\u003cli\u003eContains collection instructions\u003c\/li\u003e\n\u003cli\u003eSample Cards for collecting a dried urine sample\u003c\/li\u003e\n\u003cli\u003eInstructions on How to Use Collection Kit\u003c\/li\u003e\n\u003cli\u003eReturn Envelope\u003c\/li\u003e\n\u003cli\u003eShipping instruction\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eAre You Familiar With Following Questions?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003ePeople who have difficulty sleeping may have various questions related to their insomnia or sleep disturbances. Here are some common questions that individuals with sleep issues may ask:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eWhy am I having trouble falling asleep?\u003c\/li\u003e\n\u003cli\u003eWhat could be causing my frequent waking during the night?\u003c\/li\u003e\n\u003cli\u003eHow can I improve the quality of my sleep?\u003c\/li\u003e\n\u003cli\u003eAre there any lifestyle changes I can make to promote better sleep?\u003c\/li\u003e\n\u003cli\u003eWhat are some effective strategies for managing racing thoughts or an overactive mind at night?\u003c\/li\u003e\n\u003cli\u003eIs it normal to feel anxious or stressed before bed, and how can I reduce these feelings?\u003c\/li\u003e\n\u003cli\u003eAre there any natural remedies or supplements that may help me sleep better?\u003c\/li\u003e\n\u003cli\u003eWhen should I seek professional help for my sleep problems?\u003c\/li\u003e\n\u003cli\u003eWhat is the recommended amount of sleep for someone my age, and how can I ensure I’m getting enough?\u003c\/li\u003e\n\u003cli\u003eCan certain medications or medical conditions affect my sleep?\u003c\/li\u003e\n\u003cli\u003eHow can I establish a consistent sleep schedule and routine?\u003c\/li\u003e\n\u003cli\u003eWhat are some relaxation techniques or practices I can try before bed to promote sleep?\u003c\/li\u003e\n\u003cli\u003eAre there any underlying sleep disorders that I should be aware of and get evaluated for?\u003c\/li\u003e\n\u003cli\u003eHow can I address and overcome insomnia or sleep anxiety?\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIt’s important to note that sleep concerns can be complex, and individual experiences may vary. Our Sleep Balance Test Kit might answer your questions. After receiving your test result, we recommend consulting with a healthcare professional, such as a sleep specialist or doctor, who can provide personalised advice and guidance based on an individual’s specific sleep difficulties.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eAdvantages of Sleep Balance Profile Test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eHere are some potential benefits of the Sleep Balance Test in dried urine spot:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNo more 2:00 am wake-ups — more accurate results\u003c\/li\u003e\n\u003cli\u003eMeasures hormones at 4-time points\u003c\/li\u003e\n\u003cli\u003eProvides a true 24-hour sleep-wake pattern\u003c\/li\u003e\n\u003cli\u003eNo jug urine collection. Collect your sample through Dried Urine Spot Sample Card and post it to our lab.\u003c\/li\u003e\n\u003cli\u003eAssessment of hormone levels that may be affecting sleep patterns, such as cortisol and melatonin.\u003c\/li\u003e\n\u003cli\u003eEvaluation of circadian rhythm disruptions or irregularities.\u003c\/li\u003e\n\u003cli\u003ePersonalised treatment approach based on individual hormone profiles.\u003c\/li\u003e\n\u003cli\u003eIdentification of underlying causes of sleep disturbances.\u003c\/li\u003e\n\u003cli\u003eMonitoring treatment progress over time.\u003c\/li\u003e\n\u003cli\u003eImproved sleep management through better understanding of hormone imbalances.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eLosing Sleep? It Could Be Hormones\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eLack of sleep, also known as sleep deprivation, can manifest with various symptoms including fatigue, daytime sleepiness, difficulty concentrating, poor memory, irritability, mood changes, reduced motivation, impaired judgment, increased appetite, weakened immune function, reduced libido, headaches, muscle aches and weakness, blurred vision, increased risk of accidents, inability to get to sleep or stay asleep, frequent or early waking, and weight gain.\u003c\/p\u003e\n\u003cp\u003eIf two or more of these symptoms persist, Sleep Balance testing can identify whether it’s a hormonal imbalance. Simple testing can reveal whether your hormones are the hidden barrier to your restful sleep.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eHidden Barriers to Restful Sleep\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eDue to life and work lifestyles, many people suffer from some degree of insomnia; it’s surprising that many are still unaware of the connection between hormones and sleep. Several hormones are key to the sleep-wake cycle, and an imbalance of these levels can sabotage slumber night after a sleepless night.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eHormones \u0026amp; Your Sleep\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eMany adults are losing sleep because of stress – the constant companion of modern life. Cortisol is the hormone released by our bodies in response to stress, and chronically elevated levels are known to impair our ability to sleep. Additionally, the gradual decline in the production of the sleep hormone melatonin as we age triggers imbalances directly related to sleep.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eUnderstanding The Sleep-Wake Cycle\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eIn a perfect world, the master stress hormone cortisol should be in sync with the master sleep hormone melatonin. Each hormone counter-balances the other in a precise rhythm – when cortisol is high, melatonin should be low, and when melatonin is high, cortisol should be low. When this balance is upset, we find ourselves longing for sleep that never comes.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eThe Downside of Chronic Sleep Loss\u003c\/strong\u003e\u003c\/span\u003e\u003cbr\u003eThe benefits of adequate sleep cannot be overstated. According to the Department of Health \u0026amp; Human Services, over a third of adults report daytime sleepiness so severe it interferes with work, decision making and social functioning. In fact, depression, obesity and diabetes are just three of the long-term consequences of sleep deprivation – defined as six or fewer hours per night.\u003c\/p\u003e","brand":"ZRT Lab","offers":[{"title":"Default Title","offer_id":32923515017,"sku":"1003","price":289.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Sleep-Hormone-Profile-I.webp?v=1792667403"},{"product_id":"menstrual-cycle-mapping","title":"Menstrual Cycle Mapping Test – 1-Month Hormone Tracking at Home","description":"\u003ch2\u003eMenstrual Cycle Mapping Test (1 Month)\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e U-328 Menstrual Cycle Mapping Test | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Dried Urine | \u003cstrong\u003eTechnology:\u003c\/strong\u003e Advanced analysis with specialist laboratory interpretation included | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory (CLIA-certified) | \u003cstrong\u003eTest Result:\u003c\/strong\u003e in 3-5 working days | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMenstrual Cycle Mapping Test (One Month)\u003c\/strong\u003e is a comprehensive and invaluable tool for assessing hormonal fluctuations throughout the menstrual cycle. This cutting-edge test provides an extensive evaluation of key hormones associated with the menstrual cycle over a duration of one month. By measuring Progesterone (PDG), Estrogen (E1G), Luteinizing Hormone (LH), and Creatinine (CRTN) levels, we can gain deep insights into the hormonal patterns and changes occurring throughout different phases of the menstrual cycle. This information is vital for understanding fertility, identifying hormone imbalances, and optimising reproductive health.\u003c\/p\u003e\n\u003cp\u003eThe following hormone levels will be assessed:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eProgesterone (PDG x 15)\u003c\/li\u003e\n\u003cli\u003eEstrogen (E1G x 15)\u003c\/li\u003e\n\u003cli\u003eLuteinizing Hormone (LH x 15)\u003c\/li\u003e\n\u003cli\u003eCreatinine (CRTN x 15)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTest Result:\u003c\/strong\u003e You will receive your test result via email within 3-5 working days after the Laboratory receives your sample. On your test result, you will find your hormone levels in graphics and numbers. You will also find the laboratory’s comments by a Hormone Specialist PhD. In the comments, the doctor will explain your hormone levels and what needs to be done next.\u003c\/p\u003e\n\u003cp\u003eClick to see Sample Report: \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/dried-urine-menstrual-cycle-mapping.pdf?v=1786976488\" target=\"_blank\" rel=\"noopener noreferrer nofollow\"\u003eMenstrual Cycle Mapping Report \u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cu\u003eKey Features\u003c\/u\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eComprehensive Hormonal Assessment: The Menstrual Cycle Mapping Test provides a thorough evaluation of hormones associated with the menstrual cycle over a period of one month, allowing for a detailed analysis of hormone fluctuations throughout different phases of the cycle.\u003c\/li\u003e\n\u003cli\u003eAssessment of Progesterone: Progesterone plays a crucial role in preparing the uterus for pregnancy and maintaining a healthy menstrual cycle. Monitoring progesterone levels can help identify issues such as luteal phase defects or hormonal imbalances that may affect fertility and menstrual regularity.\u003c\/li\u003e\n\u003cli\u003eEvaluation of Estrogen: Estrogen is responsible for the development of secondary sexual characteristics and regulation of the menstrual cycle. Measuring estrogen levels can help assess the adequacy of follicular development and provide information about hormonal balance.\u003c\/li\u003e\n\u003cli\u003eTracking Luteinizing Hormone (LH): LH is responsible for triggering ovulation. Monitoring LH levels can help determine the timing of ovulation, which is essential for optimizing fertility and planning for pregnancy.\u003c\/li\u003e\n\u003cli\u003eCreatinine Assessment: Creatinine is measured to assess the concentration of urine and ensure accurate hormone measurements.\u003c\/li\u003e\n\u003cli\u003eMost Convenient Method for Month-Long Testing: Our laboratory-dried urine method offers a simple method for collecting samples at home over a month. Patients collect urine on a filter card every other morning and let them dry. Dried cards are stable at room temperature, easy to store and send back to the lab for analysis.\u003c\/li\u003e\n\u003cli\u003eNo refrigeration or freezing is necessary.\u003c\/li\u003e\n\u003cli\u003eTest samples can be collected in the comfort of your home.\u003c\/li\u003e\n\u003cli\u003eFree delivery in the UK.\u003c\/li\u003e\n\u003cli\u003eCustomers are responsible for shipping their samples to the laboratory.\u003c\/li\u003e\n\u003cli\u003eThe test kit includes a laboratory fee: no additional laboratory cost or tax.\u003c\/li\u003e\n\u003cli\u003eThe test must be used within 12 months after the purchase date.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cu\u003eTest Kit Pack Includes:\u003c\/u\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTest Requisition Form includes Symptom Checklist\u003c\/li\u003e\n\u003cli\u003eUrine Spot collecting kit (for a month)\u003c\/li\u003e\n\u003cli\u003eRequisition Form to complete, including your personal and medical history\u003c\/li\u003e\n\u003cli\u003eContains collection instructions\u003c\/li\u003e\n\u003cli\u003eShipping Instruction\u003c\/li\u003e\n\u003cli\u003eReturn Envelope\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eEvidence shows that hormonal imbalances can be the root cause of many chronic health issues, and imbalances that affect a woman’s menstrual cycle are no exception. Conditions that can be influenced by a woman’s menstrual hormones include premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD) and infertility. Out-of-balance levels can contribute to symptoms such as migraines, mood swings, and heavy bleeding or painful periods.\u003c\/p\u003e\n\u003cp\u003eWhen hormone testing conducted on a single day during the luteal phase doesn’t provide enough diagnostic information, a month-long hormone assessment can be helpful. This detailed, multi-point map provides a complete picture of a woman’s levels over the course of one menstrual cycle, resulting in the ability to create more precise treatment plans.\u003c\/p\u003e\n\u003cp\u003eMenstrual cycle mapping can be vital to assessing conditions such as:\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cu\u003eLuteal Phase Defect\u003c\/u\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eLuteal Phase Defect (LPD) is a condition characterized by an insufficient or shortened luteal phase in the menstrual cycle. The luteal phase is the second half of the menstrual cycle, following ovulation, and is important for preparing the uterus for the possible implantation of a fertilized egg. During this phase, the hormone progesterone is primarily produced by the corpus luteum, a temporary structure formed after ovulation.\u003c\/p\u003e\n\u003cp\u003eIn cases of luteal phase defects, the corpus luteum may not produce enough progesterone or may have a shorter lifespan, leading to a deficiency in progesterone levels. This deficiency can negatively impact the endometrium, making it less receptive to embryo implantation. As a result, women with LPD may experience difficulties in achieving or maintaining a pregnancy.\u003c\/p\u003e\n\u003cp\u003eTreatment options for luteal phase defects aim to address the underlying cause and restore normal hormonal balance. This may involve hormone replacement therapy, such as progesterone supplementation during the luteal phase, or medications to regulate ovulation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cu\u003eAnovulation\u003c\/u\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAnovulation refers to a condition in which a woman does not ovulate, meaning her ovaries do not release a mature egg during the menstrual cycle. When ovulation does not occur, LH levels are consistently elevated. Estrogen levels are consistent and lower as compared to the anovulatory cycle, and progesterone levels are consistently low. Testing helps providers find out if a woman has an adequate LH surge to induce ovulation and takes away the guesswork as to when they are entering their luteal phase.\u003c\/p\u003e\n\u003cp\u003eSeveral factors can contribute to anovulation, including hormonal imbalances, polycystic ovary syndrome (PCOS), thyroid disorders, excessive exercise, stress, obesity, and certain medications.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cu\u003ePremenstrual Syndrome (PMS)\u003c\/u\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePremenstrual Syndrome (PMS) refers to a collection of physical, emotional, and behavioural symptoms that occur in the days or weeks leading up to menstruation. The exact cause of PMS is not fully understood, but it is believed to be related to hormonal changes during the menstrual cycle. Fluctuations in estrogen and progesterone levels, as well as alterations in neurotransmitters like serotonin, may contribute to the development of symptoms.\u003c\/p\u003e\n\u003cp\u003ePMS symptoms can vary widely between individuals but commonly include breast tenderness, bloating, fatigue, headache, joint or muscle pain, mood swings, irritability, anxiety, depression, sleep disturbances, and changes in appetite. Testing highlights estrogen or progesterone deficiency or excess at key points in the cycle and helps get to the root of these hormone-related symptoms.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cu\u003eWho Can Benefit from Menstrual Cycle Mapping?\u003c\/u\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eWomen Planning for Pregnancy: Menstrual Cycle Mapping can provide valuable insights into the timing of ovulation, the length of your luteal phase, and hormone fluctuations throughout your cycle.\u003c\/li\u003e\n\u003cli\u003eWomen with Irregular Menstrual Cycles: Menstrual Cycle Mapping can help identify any underlying issues or hormonal imbalances that may be causing the irregularity.\u003c\/li\u003e\n\u003cli\u003eIndividuals with Suspected Hormonal Imbalances: Menstrual Cycle Mapping is useful for assessing hormone levels such as Progesterone (PDG), Estrogen (E1G), Luteinizing Hormone (LH), and Creatinine (CRTN).\u003c\/li\u003e\n\u003cli\u003eWomen Monitoring Fertility Treatments: Menstrual Cycle Mapping can provide crucial information about the effectiveness of treatments, the timing of ovulation, and the response of the ovaries to medications.\u003c\/li\u003e\n\u003cli\u003eThose Seeking a Deeper Understanding of Their Menstrual Health: Menstrual Cycle Mapping is beneficial for anyone who wants to gain a comprehensive understanding of their menstrual cycle, hormone levels, and overall reproductive health.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003eThis test is not designed for women who are on birth control, supplementing with hormones, or post-menopausal.\u003c\/p\u003e\n\u003cp\u003eWomen who are interested in this test for assessing fertility may also consider \u003ca href=\"https:\/\/hormonelab.co.uk\/collections\/multi-hormone-tests\/products\/fertility-profile-hormone-testing-saliva-and-blood-spot\" target=\"_blank\" rel=\"noopener noreferrer nofollow\"\u003e\u003cstrong\u003eZRT’s Fertility Profile.\u003c\/strong\u003e\u003c\/a\u003e While Menstrual Cycle Mapping reveals three hormone levels that can pinpoint the time of ovulation, the Fertility Profile identifies a broader array of 12 tests that help assess imbalances or conditions that affect whether a woman can get and stay pregnant.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/menstrual-cycle-mapping-pdf.pdf?15701961406056802517\" target=\"_blank\" rel=\"noopener noreferrer nofollow\"\u003e\u003cstrong\u003eDatasheet Menstrual Cycle Mapping\u003c\/strong\u003e\u003c\/a\u003e   \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/menstrual-cycle-mapping-sample-report.pdf?15701961406056802517\" target=\"_blank\" rel=\"noopener noreferrer nofollow\"\u003e\u003cstrong\u003eSample Report Menstrual Cycle Mapping\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/menstrual-cycle-mapping-instructions.pdf?2265\" target=\"_blank\" rel=\"noopener noreferrer nofollow\"\u003e\u003cstrong\u003eMenstrual Cycle Mapping Instructions\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"ZRT","offers":[{"title":"Default Title","offer_id":2003980713993,"sku":"10033","price":377.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Menstrual-Cycle-Mapping-Profile.webp?v=1792665711"},{"product_id":"neurotransmitter-testing-neuro-advanced-profile","title":"Advanced Neurotransmitter Test Kit (LCMS) | 26 Markers","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e U-325 Advanced Neurotransmitter Test  | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Dried Urine (4 collections) | \u003cstrong\u003eTechnology:\u003c\/strong\u003e Advanced LCMS analysis with specialist laboratory interpretation included | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory (CLIA-certified) | \u003cstrong\u003eTest Result:\u003c\/strong\u003e in 3-5 working days | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003eZRT’s dried urine method uses four timed collections across the day, without requiring you to collect every urination in a large 24-hour container.\u003c\/p\u003e\n\u003cp\u003eThe Advanced Neurotransmitter Test Kit is one of the most comprehensive at-home neurotransmitter tests available, measuring \u003cstrong\u003e26 neurotransmitters, metabolites, amino acid precursors, and related markers\u003c\/strong\u003e using advanced LC-MS (Liquid Chromatography Mass Spectrometry) technology.\u003c\/p\u003e\n\u003cp\u003eNeurotransmitters are the chemical messengers that allow billions of nerve cells throughout the brain and nervous system to communicate with one another. They influence virtually every aspect of physical and mental wellbeing, including mood, stress response, motivation, concentration, memory, sleep quality, energy levels, emotional resilience, behaviour, and cognitive performance.\u003c\/p\u003e\n\u003cp\u003eWhen neurotransmitters become imbalanced, the effects can extend far beyond mental health. Many individuals struggling with persistent fatigue, brain fog, anxiety, poor sleep, low motivation, mood swings, irritability, ADHD symptoms, or chronic stress may unknowingly have underlying neurochemical imbalances contributing to their symptoms.\u003c\/p\u003e\n\u003cp\u003eThis advanced neurotransmitter profile provides a detailed assessment of key neurotransmitter pathways, helping you and your healthcare practitioner gain a clearer understanding of how your nervous system may be functioning and identify areas that may benefit from personalised nutritional, lifestyle, or wellness interventions.\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eWhat Does the Advanced Neurotransmitter Test  Measure?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eNeuro Advanced Profile Includes:\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eGamma-aminobutyric acid (GABA) Test\u003c\/td\u003e\n\u003ctd\u003eGlutamate (Glu) Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGlycine (Gly) Test\u003c\/td\u003e\n\u003ctd\u003eDopamine (DA) Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eEpinephrine (Epi) Test\u003c\/td\u003e\n\u003ctd\u003eNorepinephrine (NE) Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHistamine (HIST) Test\u003c\/td\u003e\n\u003ctd\u003eSerotonin (5-HT) Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePhenethylamine (PEA) Test\u003c\/td\u003e\n\u003ctd\u003eDOPAC Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHomovanillic Acid (HVA) Test\u003c\/td\u003e\n\u003ctd\u003e5-HIAA Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNormetanephrine (NMN) Test\u003c\/td\u003e\n\u003ctd\u003eVanillylmandelic Acid (VMA) Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTryptophan (Trp) Test\u003c\/td\u003e\n\u003ctd\u003eKynurenine (Kyn) Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eKynurenic Acid (KynAc) Test\u003c\/td\u003e\n\u003ctd\u003e3-Hydroxykynurenine (3-OHKyn) Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eXanthurenic Acid Test\u003c\/td\u003e\n\u003ctd\u003eTaurine Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGlutamine Test\u003c\/td\u003e\n\u003ctd\u003eHistidine Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eN-Methylhistamine Test\u003c\/td\u003e\n\u003ctd\u003eTyrosine Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTyramine Test\u003c\/td\u003e\n\u003ctd\u003eCreatinine (Crtn) Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eCreatinine is included in the 26-marker total. It helps account for differences in urine concentration when interpreting the urinary results.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTest Sample Report:\u003c\/strong\u003e Click to see \u0026gt;\u0026gt; \u003ca title=\"Advanced Neurotransmitter Test Report\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/advanced-neurotransmitters_7b487e14-4f01-4507-8446-edb06192ccaf.pdf?v=1589397181\"\u003e\u003cstrong\u003eAdvanced Neurotransmitter Test Report\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eNot Sure Which Test Is Right for You?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca class=\"text-link\" href=\"mailto:info@hormonelab.co.uk\" rel=\"nofollow\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours with a suggestion.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eWhy Is Neurotransmitter Testing Important?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eMany symptoms associated with neurotransmitter imbalances can appear similar on the surface but may have very different underlying causes.\u003c\/p\u003e\n\u003cp\u003eSimilar symptoms can occur in people with different biochemical patterns. Reviewing neurotransmitters alongside related metabolites and precursors helps your practitioner assess patterns of neurotransmitter metabolism. These urinary results should be considered alongside your symptoms, medical history, medicines and supplements; they do not establish the cause of symptoms or directly measure neurotransmitter levels in the brain.\u003c\/p\u003e\n\u003cp\u003eWithout testing, treatment strategies often rely on assumptions or trial-and-error approaches. Neurotransmitter testing provides objective data that may help identify patterns within the nervous system, allowing more informed decisions regarding diet, supplementation, lifestyle modifications, stress management, and other wellness strategies.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eWhat Are Neurotransmitters?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eNeurotransmitters are naturally occurring chemical messengers responsible for transmitting signals between nerve cells throughout the brain and body. They help regulate:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eMood and emotional wellbeing\u003c\/li\u003e\n\u003cli\u003eStress resilience\u003c\/li\u003e\n\u003cli\u003eSleep quality\u003c\/li\u003e\n\u003cli\u003eFocus and concentration\u003c\/li\u003e\n\u003cli\u003eMemory and learning\u003c\/li\u003e\n\u003cli\u003eMotivation and reward pathways\u003c\/li\u003e\n\u003cli\u003eEnergy production\u003c\/li\u003e\n\u003cli\u003eBehaviour and impulse control\u003c\/li\u003e\n\u003cli\u003eCognitive performance\u003c\/li\u003e\n\u003cli\u003eHormonal communication\u003c\/li\u003e\n\u003cli\u003eNervous system regulation\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003cdiv\u003e\n\u003ch2\u003e\u003cstrong\u003eCould This Test Help You Explore Your Symptoms?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eThis advanced neurotransmitter profile evaluates 26 markers involved in mood regulation, stress response, focus, motivation, sleep, and emotional wellbeing. By measuring neurotransmitters, their metabolites, and key amino acid precursors, the test provides a broader assessment of the pathways that may contribute to common neurological and emotional symptoms.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eFeeling Anxious or Tense\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eAnxiety may present as excessive worry, nervousness, physical tension, racing thoughts, or feeling constantly on edge.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow this test may help:\u003c\/strong\u003e The profile assesses calming and stimulating neurotransmitter pathways, including \u003cstrong\u003eGABA, Glutamate, Glycine, Serotonin, Norepinephrine, Epinephrine, NMN, and VMA\u003c\/strong\u003e, helping to evaluate biochemical factors involved in stress response and nervous system balance.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eLow Mood\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eLow mood may include sadness, reduced enjoyment, emotional withdrawal, or feeling less positive than usual.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow this test may help:\u003c\/strong\u003e The profile measures \u003cstrong\u003eSerotonin, Dopamine, Tryptophan, 5-HIAA, DOPAC, HVA, and PEA\u003c\/strong\u003e, providing information about neurotransmitter pathways associated with mood, reward, pleasure, and emotional wellbeing.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eBrain Fog or Difficulty Concentrating\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eSymptoms may include poor focus, distractibility, reduced mental clarity, forgetfulness, or difficulty completing tasks.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow this test may help:\u003c\/strong\u003e The profile evaluates \u003cstrong\u003eDopamine, Norepinephrine, Tyrosine, Glutamate, Tryptophan, and Kynurenine pathway markers\u003c\/strong\u003e, which are involved in attention, concentration, cognitive performance, and information processing.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003ePersistent Tiredness or Low Motivation\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eLow energy, reduced drive, and lack of motivation can affect work, exercise, and daily activities.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow this test may help:\u003c\/strong\u003e The profile assesses \u003cstrong\u003eDopamine, PEA, Norepinephrine, Epinephrine, DOPAC, HVA, and Tyrosine\u003c\/strong\u003e, helping to evaluate neurotransmitter pathways involved in alertness, motivation, mental energy, and reward.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eMood Changes or Irritability\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eFrequent mood fluctuations, frustration, emotional sensitivity, or irritability may be associated with changes in neurotransmitter activity.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow this test may help:\u003c\/strong\u003e The profile examines \u003cstrong\u003eSerotonin, Dopamine, GABA, Glutamate, Glycine, and related metabolites\u003c\/strong\u003e, providing insight into pathways involved in emotional regulation and mood stability.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eDifficulty Falling Asleep, Staying Asleep or Waking Refreshed\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eSleep quality depends on healthy communication between stimulating and calming neurological pathways.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow this test may help:\u003c\/strong\u003e The profile measures \u003cstrong\u003eGABA, Glycine, Taurine, Serotonin, Glutamate, Histamine, and Tryptophan-related markers\u003c\/strong\u003e, which are involved in relaxation, sleep regulation, and nervous system balance.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eFeeling Overwhelmed or Finding Stress Difficult to Manage\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eSome individuals feel unable to cope with everyday pressures or recover from stress.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow this test may help:\u003c\/strong\u003e The profile evaluates \u003cstrong\u003eNorepinephrine, Epinephrine, NMN, VMA, GABA, Serotonin, and Glutamate\u003c\/strong\u003e, helping to assess neurotransmitter pathways involved in stress resilience and the body's response to challenge.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eRestlessness or Impulsivity\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eSymptoms may include difficulty sitting still, acting impulsively, mental hyperactivity, or feeling unable to relax.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow this test may help:\u003c\/strong\u003e The profile measures \u003cstrong\u003eDopamine, Norepinephrine, Epinephrine, PEA, GABA, and Glutamate\u003c\/strong\u003e, providing information about pathways involved in attention, behavioural regulation, motivation, and nervous system stimulation.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003ePremenstrual Mood Changes or Irritability\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eSome women experience increased emotional sensitivity, irritability, low mood, or anxiety before menstruation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow this test may help:\u003c\/strong\u003e The profile evaluates \u003cstrong\u003eSerotonin, GABA, Dopamine, Tryptophan, and 5-HIAA\u003c\/strong\u003e, helping to assess neurotransmitter pathways that may influence mood and emotional wellbeing during the menstrual cycle.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eThe Relationship Between Neurotransmitters, Hormones and Stress\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eHormones and neurotransmitters work closely together. Hormonal imbalances can influence neurotransmitter production and activity, while neurotransmitter imbalances can affect hormone signalling and stress responses.\u003c\/p\u003e\n\u003cp\u003eThis kit does not include hormone measurements.\u003c\/p\u003e\n\u003cp\u003eClick to see our \u003ca title=\"Neurotransmitters and Hormone Test\" href=\"https:\/\/hormonelab.co.uk\/collections\/neurotransmitters\/products\/saliva-lcms-hormones-7-dried-urine-lcms-neurotransitters\"\u003e\u003cstrong\u003eNeurotransmitters and Hormone Tests\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2 data-pm-slice=\"1 1 []\"\u003e\u003cstrong\u003eDried Urine Sample Collection Instructions\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eThis test requires dried urine samples only. No saliva collection is needed.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBefore You Begin\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eRead the instructions supplied with your kit. Record all current medications, supplements and hormone treatments on the Test Requisition Form.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eChoosing Your Collection Day\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMen and children:\u003c\/strong\u003e Collect on any day of the month.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWomen who do not menstruate, including postmenopausal women:\u003c\/strong\u003e Collect on any day of the month.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWomen with regular periods:\u003c\/strong\u003e Choose a non-bleeding day. This urine-only test does not require collection on a specific day of your menstrual cycle.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWomen with irregular or infrequent periods:\u003c\/strong\u003e Collect on any non-bleeding day.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAvoid collecting during menstruation or whenever blood may be present in your urine.\u003c\/strong\u003e If you use hormone treatments, also follow the guidance below.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhen to Collect\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAll groups should collect samples at the following four times:\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 117.563px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003cth style=\"width: 13.9185%; height: 19.5938px;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/th\u003e\n\u003cth style=\"width: 81.7455%; height: 19.5938px;\"\u003e\u003cstrong\u003eCollection Time\u003c\/strong\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 13.9185%; height: 19.5938px;\"\u003e\u003cstrong\u003e1\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 81.7455%; height: 19.5938px;\"\u003eYour first urination immediately upon waking\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 13.9185%; height: 39.1875px;\"\u003e\u003cstrong\u003e2\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 81.7455%; height: 39.1875px;\"\u003eYour second urination, approximately two hours after the first collection\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 13.9185%; height: 19.5938px;\"\u003e\u003cstrong\u003e3\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 81.7455%; height: 19.5938px;\"\u003eJust before dinner\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 13.9185%; height: 19.5938px;\"\u003e\u003cstrong\u003e4\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 81.7455%; height: 19.5938px;\"\u003eJust before bedtime\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eBefore your first collection, do not eat, drink anything other than water, or take vitamins or supplements. Follow your healthcare provider’s advice about medication timing; do not stop prescribed medication without their advice.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLimit fluid intake to no more than approximately 240 ml (8 oz) during the hour before each collection\u003c\/strong\u003e to avoid diluting your sample.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow to Collect Each Sample\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eRemove a collection card from its bag. Write your name, collection date and time on the card before collecting.\u003c\/li\u003e\n\u003cli\u003eOpen the cover and fold it away from the filter paper. Avoid touching the filter paper.\u003c\/li\u003e\n\u003cli\u003eFully saturate the filter paper by urinating directly onto it, or collect urine in a clean cup and dip the paper up to the top black dashed line.\u003c\/li\u003e\n\u003cli\u003eHang or tape the card somewhere secure to dry. Ensure the wet filter paper does not touch anything.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAllow the sample to dry completely for at least six hours.\u003c\/strong\u003e Once completely dry, refold the card, place it in its bag and seal it. Do not leave samples outside the bag for longer than 24 hours.\u003c\/li\u003e\n\u003cli\u003eRepeat these steps for each collection time.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eIf You Use Hormone Treatments\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eRecord all hormone treatments on your Test Requisition Form. Follow the hormone-use instructions supplied with your kit and your healthcare provider’s advice. Do not stop prescribed hormone treatment without their advice.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMorning hormones:\u003c\/strong\u003e Take or apply your usual morning dose after the first urine collection. Wash your hands thoroughly afterwards, especially after applying topical hormones.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNighttime hormones:\u003c\/strong\u003e Collect your bedtime sample before taking or applying your nighttime dose.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVaginal hormones:\u003c\/strong\u003e The laboratory’s instructions advise avoiding vaginal hormone use during the collection day until after the final urine sample. Discuss timing with your healthcare provider if needed.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eIf You Miss a Collection\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCollect the missed sample at the same time the following day. For example, collect a missed evening sample the following evening. Record the actual collection date and time on both the card and the Test Requisition Form, then follow the same drying and sealing instructions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReturning Your Samples\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eComplete the Test Requisition Form in full. Place it, any additional paperwork and all sealed, completely dry samples into the test kit box. Pack and return the kit according to the return instructions provided.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImportant:\u003c\/strong\u003e Urine samples that are wet, unsealed, excessively diluted or more than 30 days old will not be processed.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCollection Instructions:\u003c\/strong\u003e \u003ca title=\"Saliva and Dried Urine Collection Instructions\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Saliva_Dried_Urine_Collection_Instructions.pdf?v=1785413203\"\u003eView dried urine collection instructions\u003c\/a\u003e\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eAdvanced LC-MS Technology\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eThis test uses \u003cstrong\u003eLiquid Chromatography Mass Spectrometry (LC-MS)\u003c\/strong\u003e, one of the most advanced analytical technologies available for biological testing. Benefits include high analytical sensitivity, excellent specificity, reliable measurement of multiple markers, and detailed neurochemical assessment with professional interpretation.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eConvenient At-Home Collection\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eUnlike traditional 24-hour urine collections, this test uses \u003cstrong\u003efour simple dried urine collections throughout the day\u003c\/strong\u003e. Non-invasive, no large containers, samples remain stable after drying, and can be returned by post. Suitable for adults and children.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eHow the Test Works\u003c\/strong\u003e\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrder your kit\u003c\/strong\u003e — delivered directly to your door\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCollect four dried urine samples\u003c\/strong\u003e at specific times during the day using the provided collection strips\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePost your samples\u003c\/strong\u003e to the laboratory using the provided instructions\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReceive your results by email\u003c\/strong\u003e within \u003cstrong\u003e3–5 working days\u003c\/strong\u003e of the lab receiving your samples\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003e\u003cstrong\u003eWhat You Receive With Your Results\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eGraphical neurotransmitter results with individual marker values and reference ranges\u003c\/li\u003e\n\u003cli\u003eMetabolite analysis and neurotransmitter pathway assessment\u003c\/li\u003e\n\u003cli\u003eSpecialist PhD laboratory interpretation\u003c\/li\u003e\n\u003cli\u003eGuidance on possible next steps\u003c\/li\u003e\n\u003cli\u003eLaboratory analysis included; customers pay return postage to the laboratory\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eImportant Information\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eLaboratory analysis is included in the price\u003c\/li\u003e\n\u003cli\u003eCustomers pay return postage to the laboratory\u003c\/li\u003e\n\u003cli\u003eTest kit valid for 12 months from purchase date\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eAbout ZRT Laboratory\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePioneers of at-home dried urine neurotransmitter and hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardisation (HoSt) Program\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003eRigorous internal and external quality assurance programmes\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eHormone Lab UK (Testfield UK Ltd) is the official UK test provider for ZRT Laboratory. All samples are analysed by ZRT Laboratory, a CLIA-certified laboratory with over 25 years of experience in hormone, neurotransmitter, and wellness testing.\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eFrequently Asked Questions\u003c\/strong\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eWhat is a neurotransmitter test?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eA neurotransmitter test measures key chemical messengers involved in communication between nerve cells throughout the brain and nervous system. This advanced test evaluates \u003cstrong\u003e26 neurotransmitter-related markers\u003c\/strong\u003e using dried urine samples collected throughout the day.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eWhy should I test my neurotransmitters?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eNeurotransmitter imbalances may be associated with anxiety, low mood, brain fog, fatigue, poor concentration, sleep disturbances, ADHD-related symptoms, and reduced motivation. Testing provides objective information about your neurochemical profile and may help guide personalised wellness strategies.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eCan neurotransmitter imbalances cause anxiety?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eResearch suggests that GABA, Glutamate, Serotonin, Norepinephrine, Histamine, and Dopamine all play important roles in regulating stress responses and emotional wellbeing. Imbalances in these pathways may be associated with anxiety-related symptoms in some individuals.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eIs neurotransmitter testing useful for ADHD symptoms?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eNeurotransmitters such as Dopamine, Norepinephrine, GABA, and Serotonin play important roles in attention, focus, motivation, and impulse control. While this test cannot diagnose ADHD, it may provide useful information regarding neurotransmitter patterns associated with attention and concentration challenges.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eCan neurotransmitter imbalances affect sleep?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eYes. GABA, Glutamate, Serotonin, Histamine, Dopamine, and Norepinephrine are closely involved in sleep regulation and circadian rhythms. Imbalances may be associated with insomnia, difficulty falling asleep, or restless sleep.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eWhy are four samples collected during the day?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eFour timed collections provide samples from different points in the day without requiring you to collect every urination in a large 24-hour container. Follow the collection timetable supplied with your kit.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eWhy does this test measure neurotransmitter metabolites?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eMetabolites help assess how neurotransmitters are being produced, converted, and broken down. This additional information provides a more comprehensive understanding of neurotransmitter function than measuring parent neurotransmitters alone.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eIs this test suitable for children?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eThe dried urine collection method is non-invasive and suitable for adults and children. \u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eCan neurotransmitter testing diagnose medical conditions?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eNo. This test is not intended to diagnose, treat, cure, or prevent any disease. It provides information about neurotransmitter-related biomarkers that may help support discussions with healthcare practitioners regarding symptoms and overall wellbeing.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eYes. The full laboratory analysis fee is included. Customers pay return postage to the laboratory.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eOther Neurotransmitter Test Panels\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003ca title=\"Sleep Hormone Test (UDH I)\" href=\"https:\/\/hormonelab.co.uk\/products\/sleep-hormone-test-udh-i\"\u003e\u003cstrong\u003eU-321 | LCMS Diurnal Hormones I\u003c\/strong\u003e\u003c\/a\u003e\u003cbr\u003eFC(x4), FCn(x4), MT6s(x4), Crtn(x4)\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e\u003ca title=\"Advanced Sleep Hormone Test (UDH II)\" href=\"https:\/\/hormonelab.co.uk\/products\/advanced-sleep-hormone-test-udh-ii\"\u003e\u003cstrong\u003eU-322 | LCMS Diurnal Hormones II\u003c\/strong\u003e\u003c\/a\u003e\u003cbr\u003eFC(x4), FCn(x4), NE(x4), Epi(x4), MT6s(x4), Crtn(x4)\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e\u003ca title=\"Advanced Neurotransmitter \u0026amp; Diurnal Hormone Test | 42 Markers\" href=\"https:\/\/hormonelab.co.uk\/products\/neurotransmitter-dried-urine-hormone-test\"\u003e\u003cstrong\u003eU-342 | LCMS Neurotransmitters and Diurnal Hormones I\u003c\/strong\u003e\u003c\/a\u003e\u003cbr\u003eTrp, 5-HT, 5-HIAA, GABA, Gly, Tau, Glu, Gln, His, HIST, N-MeHist, PEA, Tyr, Tyra, DA, DOPAC, HVA, NE, NMN, Epi, VMA, Kyn, KynAc, 3OHKyn, Xanth, Crtn(x5), FC(x4), FCn(x4), MT6s(x4)\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e\u003ca title=\"Advanced Neurotransmitter \u0026amp; Hormone Test II | 50 Markers\" href=\"https:\/\/hormonelab.co.uk\/products\/advanced-neurotransmitter-hormone-test-ii\"\u003e\u003cstrong\u003eU-343 | LCMS Neurotransmitters and LCMS Diurnal Hormones II\u003c\/strong\u003e\u003c\/a\u003e\u003cbr\u003eTrp, 5-HT, 5-HIAA, GABA, Gly, Tau, Glu, Gln, His, HIST, N-MeHist, PEA, Tyr, Tyra, DA, DOPAC, HVA, NE(x5), NMN, Epi(x5), VMA, Kyn, KynAc, 3OHKyn, Xanth, Crtn(x5), FC(x4), FCn(x4), MT6s(x4)\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e\u003ca title=\"Advanced Neurotransmitter and Cortisol Test | 30 Markers\" href=\"https:\/\/hormonelab.co.uk\/products\/advanced-neurotransmitter-cortisol-test\"\u003e\u003cstrong\u003eSU-843 | Saliva 4-Point Cortisol + Dried Urine LCMS Neurotransmitters\u003c\/strong\u003e\u003c\/a\u003e\u003cbr\u003eC(x4), Trp, 5-HT, 5-HIAA, GABA, Gly, Tau, Glu, Gln, His, HIST, N-MeHist, PEA, Tyr, Tyra, DA, DOPAC, HVA, NE, NMN, Epi, VMA, Kyn, KynAc, 3OHKyn, Xanth, Crtn\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e\u003ca title=\"Advanced Neurotransmitter \u0026amp; Saliva Hormone Test I | 33 Markers\" href=\"https:\/\/hormonelab.co.uk\/products\/neurotransmitter-saliva-hormone-test-i\"\u003e\u003cstrong\u003eSU-840 | Saliva LCMS Hormones 7 + Dried Urine LCMS Neurotransmitters\u003c\/strong\u003e\u003c\/a\u003e\u003cbr\u003eE2, E3, E1, Pg, T, DS, C, Trp, 5-HT, 5-HIAA, GABA, Gly, Tau, Glu, Gln, His, HIST, N-MeHist, PEA, Tyr, Tyra, DA, DOPAC, HVA, NE, NMN, Epi, VMA, Kyn, KynAc, 3OHKyn, Xanth, Crtn\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e\u003ca title=\"Advanced Neurotransmitter \u0026amp; Hormone Test I | 49 Markers\" href=\"https:\/\/hormonelab.co.uk\/products\/advanced-neurotransmitter-hormone-test-i\"\u003e\u003cstrong\u003eSU-841 | Saliva LCMS Hormones 7 + Dried Urine LCMS Neurotransmitters and Diurnal Hormones I\u003c\/strong\u003e\u003c\/a\u003e\u003cbr\u003eE2, E3, E1, Pg, T, DS, C, Trp, 5-HT, 5-HIAA, GABA, Gly, Tau, Glu, Gln, His, HIST, N-MeHist, PEA, Tyr, Tyra, DA, DOPAC, HVA, NE, NMN, Epi, VMA, Kyn, KynAc, 3OHKyn, Xanth, Crtn(x5), FC(x4), FCn(x4), MT6s(x4)\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e\u003ca title=\"Elite Neurotransmitters \u0026amp; Saliva Hormone Test | 57 Markers\" href=\"https:\/\/hormonelab.co.uk\/products\/elite-neurotransmitter-saliva-hormone-test\"\u003e\u003cstrong\u003eSU-842 | Saliva LCMS Hormones 7 + Dried Urine LCMS Neurotransmitters and Diurnal Hormones II\u003c\/strong\u003e\u003c\/a\u003e\u003cbr\u003eE2, E3, E1, Pg, T, DS, C, Trp, 5-HT, 5-HIAA, GABA, Gly, Tau, Glu, Gln, His, HIST, N-MeHist, PEA, Tyr, Tyra, DA, DOPAC, HVA, NE(x5), NMN, Epi(x5), VMA, Kyn, KynAc, 3OHKyn, Xanth, Crtn(x5), FC(x4), FCn(x4), MT6s(x4)\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e\u003ca title=\"Neurotransmitter \u0026amp; Saliva Hormone Test II | 36 Markers\" href=\"https:\/\/hormonelab.co.uk\/products\/neurotransmitter-saliva-hormone-test-ii\"\u003e\u003cstrong\u003eSU-844 | Saliva LCMS Hormones 7 with 4-Point Cortisol + Dried Urine LCMS Neurotransmitters\u003c\/strong\u003e\u003c\/a\u003e\u003cbr\u003eE2, E3, E1, Pg, T, DS, C(x4), Trp, 5-HT, 5-HIAA, GABA, Gly, Tau, Glu, Gln, His, HIST, N-MeHist, PEA, Tyr, Tyra, DA, DOPAC, HVA, NE, NMN, Epi, VMA, Kyn, KynAc, 3OHKyn, Xanth, Crtn\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":31652330897494,"sku":"0069","price":379.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Neurotransmitters_Test.webp?v=1785073865"},{"product_id":"neurotransmitter-dried-urine-hormone-test","title":"Advanced Neurotransmitter \u0026 Diurnal Hormone Test | 42 Markers","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e U-342 Advanced Neurotransmitter \u0026amp; Diurnal Hormone Test | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Dried Urine (4 timed collections) | \u003cstrong\u003eTechnology:\u003c\/strong\u003e Advanced LCMS analysis with specialist laboratory interpretation included | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory (CLIA-certified) | \u003cstrong\u003eTest Result:\u003c\/strong\u003e in 3-5 working days | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eUnderstand the Connection Between Neurotransmitters, Stress and Sleep\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eThe \u003cstrong\u003eAdvanced Neurotransmitter \u0026amp; Diurnal Hormone Test (U-342)\u003c\/strong\u003e is a comprehensive at-home dried urine test that measures neurotransmitters and their related metabolites alongside your daily patterns of free cortisol, free cortisone, and 6-sulfatoxymelatonin — the main urinary metabolite of melatonin.\u003c\/p\u003e\n\u003cp\u003eRather than looking at one marker or one moment in the day, this profile examines important pathways involving serotonin, dopamine, GABA, glutamate, norepinephrine, epinephrine, histamine, and the kynurenine pathway. Four timed measurements each of free cortisol, free cortisone and MT6s provide urinary profiles across the collection day.\u003c\/p\u003e\n\u003cp\u003eThe result is a broader view of the biochemical patterns that may be relevant to mood, stress response, energy, concentration, and sleep. Your personalised laboratory report can help you and your healthcare professional decide whether further assessment or targeted support may be appropriate.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eWhat Does the Test Measure? (42 Markers)\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eThe total includes 26 entries in the Advanced neurotransmitter profile plus four measurements each of free cortisol, free cortisone, MT6s and creatinine. Repeated measurements contribute to the 42 total; this does not mean 42 different substances.\u003c\/p\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003e\u003cstrong\u003ePathway or Group\u003c\/strong\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cstrong\u003eMarkers Included\u003c\/strong\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSerotonin and tryptophan\u003c\/td\u003e\n\u003ctd\u003eTryptophan (Trp), Serotonin (5-HT), 5-HIAA\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGABA, glutamate and amino acids\u003c\/td\u003e\n\u003ctd\u003eGABA, Glycine (Gly), Taurine (Tau), Glutamate (Glu), Glutamine (Gln)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHistamine\u003c\/td\u003e\n\u003ctd\u003eHistidine (His), Histamine (HIST), N-Methylhistamine (N-MeHist)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePhenylethylamine\u003c\/td\u003e\n\u003ctd\u003ePhenylethylamine (PEA)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDopamine and catecholamines\u003c\/td\u003e\n\u003ctd\u003eTyrosine (Tyr), Tyramine (Tyra), Dopamine (DA), DOPAC, HVA, Norepinephrine (NE), Normetanephrine (NMN), Epinephrine (Epi), VMA\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eKynurenine pathway\u003c\/td\u003e\n\u003ctd\u003eKynurenine (Kyn), Kynurenic Acid (KynAc), 3-Hydroxykynurenine (3OHKyn), Xanthurenic Acid (Xanth)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSample correction\u003c\/td\u003e\n\u003ctd\u003eCreatinine (Crtn) ×5\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDiurnal stress hormones\u003c\/td\u003e\n\u003ctd\u003eFree Cortisol (FC) ×4, Free Cortisone (FCn) ×4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMelatonin metabolite\u003c\/td\u003e\n\u003ctd\u003e6-Sulfatoxymelatonin (MT6s) ×4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eCreatinine is included in the neurotransmitter profile and in the four timed profiles to account for urine concentration. The ×5 notation does not mean five urine collections.\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eNot Sure Which Test Is Right for You?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca class=\"text-link\" href=\"mailto:info@hormonelab.co.uk\" rel=\"nofollow\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours with a suggestion.\u003c\/p\u003e\n\u003cdiv\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eCould This Test Be Relevant to Your Symptoms?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e If you experience persistent or unexplained symptoms such as:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLow mood, irritability, or frequent mood changes\u003c\/li\u003e\n\u003cli\u003eFeeling anxious, tense, overwhelmed, or \"wired\"\u003c\/li\u003e\n\u003cli\u003eDifficulty falling asleep, staying asleep, or waking refreshed\u003c\/li\u003e\n\u003cli\u003eDaytime tiredness or fluctuating energy\u003c\/li\u003e\n\u003cli\u003ePoor concentration, mental fog, or forgetfulness\u003c\/li\u003e\n\u003cli\u003eLow motivation or reduced enjoyment\u003c\/li\u003e\n\u003cli\u003eDifficulty coping with stress\u003c\/li\u003e\n\u003cli\u003eRestlessness or feeling unable to switch off\u003c\/li\u003e\n\u003cli\u003eChanges in appetite or cravings\u003c\/li\u003e\n\u003cli\u003eLow libido\u003c\/li\u003e\n\u003cli\u003ePremenstrual mood changes\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThese symptoms can have many possible causes. However, they are commonly associated with pathways involving neurotransmitters, stress hormones, circadian rhythms, and neurotransmitter metabolism. This profile is designed to assess these interconnected systems together, helping you and your healthcare practitioner gain a broader understanding of potential biological contributors to your symptoms.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eHow This Test May Help\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eUnlike standard neurotransmitter testing, this profile evaluates:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNeurotransmitters involved in mood, motivation, focus, stress response, and relaxation\u003c\/li\u003e\n\u003cli\u003eNeurotransmitter metabolites that provide information about neurotransmitter breakdown and turnover\u003c\/li\u003e\n\u003cli\u003eAmino acid precursors used to produce neurotransmitters\u003c\/li\u003e\n\u003cli\u003eThe tryptophan-kynurenine pathway, which influences serotonin metabolism\u003c\/li\u003e\n\u003cli\u003eCortisol and cortisone patterns throughout the day\u003c\/li\u003e\n\u003cli\u003eMelatonin production through measurement of its primary urinary metabolite\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eReviewing these pathways together may help identify patterns that could warrant further investigation or monitoring.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eUnderstanding Your Symptoms\u003c\/strong\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eLow Mood, Irritability, or Frequent Mood Changes\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eMood regulation is influenced by several neurotransmitter systems, particularly serotonin, dopamine, and GABA.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelevant markers include:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSerotonin (5-HT)\u003c\/li\u003e\n\u003cli\u003e5-HIAA\u003c\/li\u003e\n\u003cli\u003eDopamine (DA)\u003c\/li\u003e\n\u003cli\u003eDOPAC\u003c\/li\u003e\n\u003cli\u003eHVA\u003c\/li\u003e\n\u003cli\u003eGABA\u003c\/li\u003e\n\u003cli\u003eTryptophan\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe test evaluates both neurotransmitters and their metabolites, providing insight into neurotransmitter production and metabolism that may be relevant when investigating mood-related symptoms.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eFeeling Anxious, Tense, Overwhelmed, or \"Wired\"\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eFeelings of anxiety and nervous tension are often associated with a balance between calming and stimulating neurotransmitter pathways.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelevant markers include:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eGABA\u003c\/li\u003e\n\u003cli\u003eGlycine\u003c\/li\u003e\n\u003cli\u003eGlutamate\u003c\/li\u003e\n\u003cli\u003eNorepinephrine\u003c\/li\u003e\n\u003cli\u003eEpinephrine\u003c\/li\u003e\n\u003cli\u003eNormetanephrine\u003c\/li\u003e\n\u003cli\u003eVMA\u003c\/li\u003e\n\u003cli\u003eCortisol and Cortisone Rhythm\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAssessing both neurotransmitters and daily stress hormone patterns may help identify whether stress-response pathways are contributing to symptoms.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eDifficulty Falling Asleep, Staying Asleep, or Waking Refreshed\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eSleep relies on healthy interactions between melatonin, cortisol, serotonin, and calming neurotransmitters.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelevant markers include:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eMT6s (Melatonin Metabolite)\u003c\/li\u003e\n\u003cli\u003eCortisol\u003c\/li\u003e\n\u003cli\u003eCortisone\u003c\/li\u003e\n\u003cli\u003eGABA\u003c\/li\u003e\n\u003cli\u003eGlycine\u003c\/li\u003e\n\u003cli\u003eSerotonin\u003c\/li\u003e\n\u003cli\u003eHistamine\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThis profile allows your practitioner to review both sleep-related neurotransmitters and your daily cortisol rhythm, which can influence sleep quality and recovery.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eDaytime Tiredness or Fluctuating Energy\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eLow energy may be linked to stress hormone regulation, neurotransmitter activity, poor sleep quality, or chronic stress.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelevant markers include:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eCortisol\u003c\/li\u003e\n\u003cli\u003eCortisone\u003c\/li\u003e\n\u003cli\u003eDopamine\u003c\/li\u003e\n\u003cli\u003eNorepinephrine\u003c\/li\u003e\n\u003cli\u003eEpinephrine\u003c\/li\u003e\n\u003cli\u003ePEA\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe four-point hormone measurements provide information about your stress hormone rhythm throughout the day, while neurotransmitter results may help assess pathways involved in alertness and motivation.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003ePoor Concentration, Mental Fog, or Forgetfulness\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eConcentration and cognitive performance depend on several neurotransmitter pathways.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelevant markers include:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eDopamine\u003c\/li\u003e\n\u003cli\u003eNorepinephrine\u003c\/li\u003e\n\u003cli\u003eGlutamate\u003c\/li\u003e\n\u003cli\u003eTyrosine\u003c\/li\u003e\n\u003cli\u003eTryptophan\u003c\/li\u003e\n\u003cli\u003eKynurenine Pathway Markers\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe results may help identify patterns affecting attention, focus, cognitive processing, and mental clarity.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eLow Motivation or Reduced Enjoyment\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eMotivation and reward perception are strongly influenced by dopamine pathways.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelevant markers include:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eDopamine\u003c\/li\u003e\n\u003cli\u003eDOPAC\u003c\/li\u003e\n\u003cli\u003eHVA\u003c\/li\u003e\n\u003cli\u003ePEA\u003c\/li\u003e\n\u003cli\u003eTyrosine\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBy assessing dopamine production and metabolism, the profile may provide additional information regarding pathways involved in motivation and drive.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eDifficulty Coping With Stress\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eSome people experience prolonged feelings of emotional or physical stress despite relatively minor day-to-day demands.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelevant markers include:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eCortisol\u003c\/li\u003e\n\u003cli\u003eCortisone\u003c\/li\u003e\n\u003cli\u003eNorepinephrine\u003c\/li\u003e\n\u003cli\u003eEpinephrine\u003c\/li\u003e\n\u003cli\u003eGABA\u003c\/li\u003e\n\u003cli\u003eSerotonin\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eReviewing stress hormones together with neurotransmitter pathways can provide a more complete picture of your body's stress response mechanisms.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eRestlessness or Feeling Unable to Switch Off\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eThis may present as physical tension, racing thoughts, inner agitation, or difficulty relaxing.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelevant markers include:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eGABA\u003c\/li\u003e\n\u003cli\u003eGlutamate\u003c\/li\u003e\n\u003cli\u003eGlycine\u003c\/li\u003e\n\u003cli\u003eNorepinephrine\u003c\/li\u003e\n\u003cli\u003eEpinephrine\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe profile evaluates both stimulating and calming pathways that may influence nervous system balance and relaxation.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eChanges in Appetite or Cravings\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eAppetite regulation is influenced by stress hormones, neurotransmitters, reward pathways, and emotional wellbeing.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelevant markers include:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSerotonin\u003c\/li\u003e\n\u003cli\u003eDopamine\u003c\/li\u003e\n\u003cli\u003ePEA\u003c\/li\u003e\n\u003cli\u003eHistamine\u003c\/li\u003e\n\u003cli\u003eCortisol\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eResults may provide insight into pathways that can influence eating behaviour, cravings, and appetite regulation.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eLow Libido\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eSexual desire and satisfaction are influenced by mood, motivation, stress response, and neurotransmitter balance.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelevant markers include:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eDopamine\u003c\/li\u003e\n\u003cli\u003eSerotonin\u003c\/li\u003e\n\u003cli\u003ePEA\u003c\/li\u003e\n\u003cli\u003eNorepinephrine\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAssessing these pathways may help identify factors that could contribute to changes in libido or sexual wellbeing.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003ePremenstrual Mood Changes\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eMood symptoms that occur before menstruation may be influenced by neurotransmitter regulation, particularly serotonin and GABA pathways.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelevant markers include:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSerotonin\u003c\/li\u003e\n\u003cli\u003e5-HIAA\u003c\/li\u003e\n\u003cli\u003eGABA\u003c\/li\u003e\n\u003cli\u003eDopamine\u003c\/li\u003e\n\u003cli\u003eTryptophan\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eEvaluation of neurotransmitter metabolism may provide useful information when investigating mood changes associated with the menstrual cycle.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eWhy Combine Neurotransmitters With Cortisol and Melatonin?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eMood, energy, stress response, and sleep are influenced by interconnected systems. A neurotransmitter-only test provides information about neurotransmitter pathways, but it does not include timed urinary cortisol or melatonin-metabolite measurements. By combining these measurements, U-342 offers a broader neuroendocrine overview:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCortisol\u003c\/strong\u003e supports the body’s response to daily demands and normally follows a day-night rhythm\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCortisone\u003c\/strong\u003e provides additional context on glucocorticoid metabolism\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e6-Sulfatoxymelatonin\u003c\/strong\u003e is a urinary metabolite of melatonin; its timed measurements provide information relevant to a review of sleep-wake patterns\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeurotransmitters, precursors and metabolites\u003c\/strong\u003e provide information about systemic production, metabolism and excretion across several biochemical pathways\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eMeasuring parent neurotransmitters alongside related metabolites provides a broader biochemical picture than considering individual markers alone. For example, this profile includes dopamine with DOPAC and HVA, and serotonin with 5-HIAA.\u003c\/p\u003e\n\u003cp\u003eThis combined information may be particularly useful when symptoms overlap — for example, poor sleep accompanied by fatigue, stress sensitivity, low mood, or reduced concentration.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eWho Is This Test For?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eThis test is suitable for children and adults seeking additional biochemical information about symptoms involving mood, stress, energy, concentration, and sleep. \u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eHow It Works\u003c\/strong\u003e\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrder your kit\u003c\/strong\u003e — delivered directly to your door\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCollect four timed dried urine samples\u003c\/strong\u003e on the collection day using the supplied filter cards at specified times\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAllow the cards to dry\u003c\/strong\u003e, then return them to the laboratory using the provided instructions\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReceive your results by email\u003c\/strong\u003e within \u003cstrong\u003e3–5 working days\u003c\/strong\u003e of the lab receiving your samples\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003ePreparing for Your Test\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eFood, drink, nicotine, medicines, and supplements may affect urinary results. Follow the current instructions supplied with your kit for preparation, collection times and any restrictions on food, drink or nicotine. \u003cstrong\u003eDo not stop prescribed medication or change treatment unless your prescribing clinician tells you to do so.\u003c\/strong\u003e Record all medicines and supplements on your requisition form.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eWhat You Receive With Your Results\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll 42 measurements displayed in numerical and graphical form\u003c\/li\u003e\n\u003cli\u003eDiurnal urinary cortisol, cortisone and MT6s profiles\u003c\/li\u003e\n\u003cli\u003eNeurotransmitter pathway analysis including metabolites and precursors\u003c\/li\u003e\n\u003cli\u003eSpecialist laboratory interpretation and personalised comments\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eDried Urine Sample Collection Instructions\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eCollect four timed dried urine samples using the supplied materials.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBefore You Begin\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eRead the instructions supplied with your kit. Record all current medications, supplements and hormone treatments on the Test Requisition Form.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eChoosing Your Collection Day\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMen and children:\u003c\/strong\u003e Collect on any day of the month.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWomen who do not menstruate, including postmenopausal women:\u003c\/strong\u003e Collect on any day of the month.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWomen with regular periods:\u003c\/strong\u003e Choose a non-bleeding day. This urine-only test does not require collection on a specific day of your menstrual cycle.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWomen with irregular or infrequent periods:\u003c\/strong\u003e Collect on any non-bleeding day.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAvoid collecting during menstruation or whenever blood may be present in your urine.\u003c\/strong\u003e If you use hormone treatments, also follow the guidance below.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhen to Collect\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAll groups should collect samples at the following four times:\u003c\/p\u003e\n\u003cdiv class=\"rte__table-wrapper\"\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cstrong\u003eCollection Time\u003c\/strong\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e1\u003c\/td\u003e\n\u003ctd\u003eYour first urination immediately upon waking\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e2\u003c\/td\u003e\n\u003ctd\u003eYour second urination, approximately two hours after the first collection\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e3\u003c\/td\u003e\n\u003ctd\u003eJust before dinner\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e4\u003c\/td\u003e\n\u003ctd\u003eJust before bedtime\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003eBefore your first collection, do not eat, drink anything other than water, or take vitamins or supplements. Follow your healthcare provider’s advice about medication timing; do not stop prescribed medication without their advice.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLimit fluid intake to no more than approximately 240 ml (8 oz) during the hour before each collection\u003c\/strong\u003e to avoid diluting your sample.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow to Collect Each Sample\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eRemove a collection card from its bag. Write your name, collection date and time on the card before collecting.\u003c\/li\u003e\n\u003cli\u003eOpen the cover and fold it away from the filter paper. Avoid touching the filter paper.\u003c\/li\u003e\n\u003cli\u003eFully saturate the filter paper by urinating directly onto it, or collect urine in a clean cup and dip the paper up to the top black dashed line.\u003c\/li\u003e\n\u003cli\u003eHang or tape the card somewhere secure to dry. Ensure the wet filter paper does not touch anything.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAllow the sample to dry completely for at least six hours.\u003c\/strong\u003e Once completely dry, refold the card, place it in its bag and seal it. Do not leave samples outside the bag for longer than 24 hours.\u003c\/li\u003e\n\u003cli\u003eRepeat these steps for each collection time.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eIf You Use Hormone Treatments\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eRecord all hormone treatments on your Test Requisition Form. Follow the hormone-use instructions supplied with your kit and your healthcare provider’s advice. Do not stop prescribed hormone treatment without their advice.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMorning hormones:\u003c\/strong\u003e Take or apply your usual morning dose after the first urine collection. Wash your hands thoroughly afterwards, especially after applying topical hormones.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNighttime hormones:\u003c\/strong\u003e Collect your bedtime sample before taking or applying your nighttime dose.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVaginal hormones:\u003c\/strong\u003e The laboratory’s instructions advise avoiding vaginal hormone use during the collection day until after the final urine sample. Discuss timing with your healthcare provider if needed.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eIf You Miss a Collection\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCollect the missed sample at the same time the following day. For example, collect a missed evening sample the following evening. Record the actual collection date and time on both the card and the Test Requisition Form, then follow the same drying and sealing instructions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReturning Your Samples\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eComplete the Test Requisition Form in full. Place it, any additional paperwork and all sealed, completely dry samples into the test kit box. Pack and return the kit according to the return instructions provided.\u003c\/p\u003e\n\u003cp\u003eA return envelope is provided with your kit. It is not prepaid; customers are responsible for return postage to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImportant:\u003c\/strong\u003e Urine samples that are wet, unsealed, excessively diluted or more than 30 days old will not be processed.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCollection Instructions:\u003c\/strong\u003e \u003ca class=\"text-link\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Saliva_Dried_Urine_Collection_Instructions.pdf?v=1785413203\" rel=\"nofollow\"\u003eView dried urine collection instructions\u003c\/a\u003e\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eWhy We Use ZRT Laboratory\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e. ZRT pioneered dried urine collection methods for multiple daily samples, making at-home neuroendocrine testing practical and accurate.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eHormone Lab UK (Testfield UK Ltd) is the official UK test provider for ZRT Laboratory.\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eImportant Information\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eLaboratory analysis is included in the price\u003c\/li\u003e\n\u003cli\u003eA return envelope is supplied. Customers pay return postage to the laboratory\u003c\/li\u003e\n\u003cli\u003eTest kit valid for 12 months from purchase date\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eFrequently Asked Questions\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is a neurotransmitter test?\u003c\/strong\u003e\u003cbr\u003eThis test measures selected neurotransmitters, their precursors, and their metabolites excreted in dried urine. The results provide information about systemic biochemical pathways and may support a broader assessment of symptoms involving mood, stress, energy, focus, or sleep.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy are samples collected at different times of day?\u003c\/strong\u003e\u003cbr\u003eUrinary cortisol, cortisone, MT6s and some neurotransmitter-related measurements vary across the day. Timed samples provide information about daily patterns and reduce reliance on a single time-point snapshot.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is 6-sulfatoxymelatonin?\u003c\/strong\u003e\u003cbr\u003e6-Sulfatoxymelatonin (MT6s) is the main metabolite of melatonin found in urine. Measuring it at several points provides a urinary profile for review alongside sleep-wake patterns.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. Return postage to the laboratory is not included.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"ZRT Lab","offers":[{"title":"Default Title","offer_id":32496953622614,"sku":"1001","price":435.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Neurotransmitters_Test.webp?v=1785073865"},{"product_id":"advanced-neurotransmitter-hormone-test-ii","title":"Advanced Neurotransmitter \u0026 Hormone Test II | 50 Markers","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e U-343 Advanced Neurotransmitter \u0026amp; Hormone Test II  | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Dried Urine, 4 Timed Collections | \u003cstrong\u003eTechnology:\u003c\/strong\u003e LC-MS | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory, CLIA-certified | \u003cstrong\u003eSpecialist Laboratory Interpretation:\u003c\/strong\u003e Included | \u003cstrong\u003eResults:\u003c\/strong\u003e 3–5 working days after the laboratory receives your samples | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Children and Adults | \u003cstrong\u003eCollect Sample At Home: No Clinic Visit Required\u003c\/strong\u003e\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003eIf poor sleep, daytime tiredness, feeling constantly “wired”, low motivation or brain fog are affecting everyday life, this combined test provides laboratory information to help you explore these concerns with your practitioner.\u003c\/p\u003e\n\u003cp\u003eThe Advanced Neurotransmitter \u0026amp; Hormone Test II combines the Advanced 26-marker urinary neurotransmitter profile with timed measurements of free cortisol, free cortisone, the melatonin metabolite MT6s, norepinephrine and epinephrine. Four at-home urine collections provide daily profiles alongside neurotransmitter-related results, bringing several areas together in one report.\u003c\/p\u003e\n\u003cp\u003eYour results include numerical values, reference ranges, graphical daily profiles and specialist laboratory interpretation, helping you prepare a more focused discussion about your symptoms and appropriate next steps.\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eWhat Does the Combined Neurotransmitter and Hormone Test Measure?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eThe panel reports 50 measurements, including repeated measurements across the day.\u003c\/p\u003e\n\u003cp\u003eThe total comprises the Advanced 26-marker profile, 12 cortisol\/cortisone\/MT6s measurements, four additional norepinephrine measurements, four additional epinephrine measurements and four additional creatinine measurements.\u003c\/p\u003e\n\u003cp\u003eThe total includes repeated measurements, not 50 different substances. Creatinine contributes to the total as a urine-concentration marker. Five reported measurements of norepinephrine, epinephrine and creatinine do not mean five urine collections.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eNeuro Advanced Profile Includes:\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eGamma-aminobutyric acid (GABA) Test\u003c\/td\u003e\n\u003ctd\u003eGlutamate (Glu) Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGlycine (Gly) Test\u003c\/td\u003e\n\u003ctd\u003eDopamine (DA) Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eEpinephrine \/ Adrenaline (Epi) Test\u003c\/td\u003e\n\u003ctd\u003eNorepinephrine \/ Noradrenaline (NE) Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHistamine (HIST) Test\u003c\/td\u003e\n\u003ctd\u003eSerotonin (5-HT) Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePhenethylamine (PEA) Test\u003c\/td\u003e\n\u003ctd\u003eDOPAC Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHomovanillic Acid (HVA) Test\u003c\/td\u003e\n\u003ctd\u003e5-HIAA Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNormetanephrine (NMN) Test\u003c\/td\u003e\n\u003ctd\u003eVanillylmandelic Acid (VMA) Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTryptophan (Trp) Test\u003c\/td\u003e\n\u003ctd\u003eKynurenine (Kyn) Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eKynurenic Acid (KynAc) Test\u003c\/td\u003e\n\u003ctd\u003e3-Hydroxykynurenine (3-OHKyn) Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eXanthurenic Acid Test\u003c\/td\u003e\n\u003ctd\u003eTaurine Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGlutamine Test\u003c\/td\u003e\n\u003ctd\u003eHistidine Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eN-Methylhistamine Test\u003c\/td\u003e\n\u003ctd\u003eTyrosine Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTyramine Test\u003c\/td\u003e\n\u003ctd\u003eCreatinine (Crtn) Test\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3\u003e\u003cstrong\u003eAdditional Daily Hormone and Sample-Correction Measurements:\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eFree Cortisol (FC): 4 measurements\u003c\/td\u003e\n\u003ctd\u003eFree Cortisone (FCn): 4 measurements\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e6-Sulfatoxymelatonin (MT6s): 4 measurements\u003c\/td\u003e\n\u003ctd\u003eNorepinephrine (NE): 4 additional measurements\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eEpinephrine (Epi): 4 additional measurements\u003c\/td\u003e\n\u003ctd\u003eCreatinine (Crtn): 4 additional measurements\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eNorepinephrine, epinephrine and creatinine are each reported five times across the combined profile, including their entries in the Advanced profile. Collection requires four timed dried urine samples.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eNot Sure Which Test Is Right for You?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eEmail \u003ca href=\"mailto:info@hormonelab.co.uk\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your age, gender, symptoms and how long you have experienced them, current medicines and supplements, existing treatments and questions for our doctors. We will forward your enquiry to our doctors and aim to respond within 24 hours with a test suggestion.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eHow Can This Test Help?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eExplore overlapping concerns:\u003c\/strong\u003e bring sleep, energy, mood, concentration and stress-related findings together in one report.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSee measured daily patterns:\u003c\/strong\u003e timed cortisol, cortisone, MT6s, norepinephrine and epinephrine results provide information from different points in your collection day.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReview related markers together:\u003c\/strong\u003e urinary neurotransmitters, precursors and metabolites provide a broader set of measurements than a single-marker test.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMake your consultation more focused:\u003c\/strong\u003e use the report and specialist interpretation to prepare questions and discuss appropriate further assessment, nutrition, lifestyle or wellbeing steps with your practitioner.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCollect conveniently at home:\u003c\/strong\u003e four dried urine collections using the supplied cards, with no clinic visit required.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eCould This Test Help You Explore Your Symptoms?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eSleep, mood, energy and concentration concerns often overlap. This profile brings urinary neurotransmitter-related results together with daily hormone, melatonin-metabolite and adrenaline-related measurements, giving your practitioner several sets of findings to review alongside your symptoms.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eLow Mood, Irritability or Frequent Mood Changes\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eLow mood, emotional sensitivity, loss of enjoyment or increased irritability can affect relationships, motivation and everyday wellbeing.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMarkers assessed include:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSerotonin (5-HT)\u003c\/li\u003e\n\u003cli\u003eDopamine (DA)\u003c\/li\u003e\n\u003cli\u003ePhenethylamine (PEA)\u003c\/li\u003e\n\u003cli\u003eGABA\u003c\/li\u003e\n\u003cli\u003eDOPAC\u003c\/li\u003e\n\u003cli\u003eHVA\u003c\/li\u003e\n\u003cli\u003e5-HIAA\u003c\/li\u003e\n\u003cli\u003eTryptophan\u003c\/li\u003e\n\u003cli\u003eKynurenine Pathway Markers\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eHow this test may help:\u003c\/strong\u003e Serotonin and dopamine are measured alongside their urinary metabolites and precursors. The daily hormone and MT6s profiles add information when mood concerns occur with poor sleep, tiredness or stress, providing a broader set of findings for your consultation.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eFeeling Anxious, Tense or Overwhelmed\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eThese concerns may include excessive worry, nervousness, racing thoughts, muscle tension, panic symptoms or difficulty relaxing.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMarkers assessed include:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eGABA\u003c\/li\u003e\n\u003cli\u003eGlutamate\u003c\/li\u003e\n\u003cli\u003eGlycine\u003c\/li\u003e\n\u003cli\u003eNorepinephrine\u003c\/li\u003e\n\u003cli\u003eEpinephrine\u003c\/li\u003e\n\u003cli\u003eNormetanephrine\u003c\/li\u003e\n\u003cli\u003eVMA\u003c\/li\u003e\n\u003cli\u003eCortisol\u003c\/li\u003e\n\u003cli\u003eCortisone\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eHow this test may help:\u003c\/strong\u003e The panel combines urinary neurotransmitter-related measurements with timed cortisol, cortisone, norepinephrine and epinephrine results. Reviewing these alongside when you feel tense or overwhelmed adds useful laboratory information to a discussion about stress, sleep and your daily routine.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eDifficulty Falling Asleep, Staying Asleep or Waking Refreshed\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eTrouble switching off, frequent waking or feeling unrefreshed can affect both daytime energy and emotional wellbeing.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMarkers assessed include:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eGABA\u003c\/li\u003e\n\u003cli\u003eGlycine\u003c\/li\u003e\n\u003cli\u003eGlutamate\u003c\/li\u003e\n\u003cli\u003eSerotonin\u003c\/li\u003e\n\u003cli\u003eHistamine\u003c\/li\u003e\n\u003cli\u003eTaurine\u003c\/li\u003e\n\u003cli\u003e6-Sulfatoxymelatonin (MT6s)\u003c\/li\u003e\n\u003cli\u003eCortisol\u003c\/li\u003e\n\u003cli\u003eCortisone\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eHow this test may help:\u003c\/strong\u003e Timed MT6s measurements provide information about urinary melatonin metabolism, while cortisol and cortisone add daily glucocorticoid profiles. Your practitioner can review these with the neurotransmitter results, your sleep diary and routine to discuss appropriate next steps.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eDaytime Fatigue or Fluctuating Energy\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eFeeling tired throughout the day, experiencing afternoon slumps or struggling with stamina can make everyday tasks harder.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMarkers assessed include:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eDopamine\u003c\/li\u003e\n\u003cli\u003eNorepinephrine\u003c\/li\u003e\n\u003cli\u003eEpinephrine\u003c\/li\u003e\n\u003cli\u003ePEA\u003c\/li\u003e\n\u003cli\u003eCortisol\u003c\/li\u003e\n\u003cli\u003eCortisone\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eHow this test may help:\u003c\/strong\u003e Timed hormone and adrenaline-related results provide measured daily patterns to review alongside the times you feel tired or more alert. The neurotransmitter profile adds information when fatigue overlaps with low motivation, poor concentration or stress.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eBrain Fog or Difficulty Concentrating\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eSymptoms may include poor focus, forgetfulness, reduced mental clarity, slow thinking or difficulty completing tasks.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMarkers assessed include:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eDopamine\u003c\/li\u003e\n\u003cli\u003eNorepinephrine\u003c\/li\u003e\n\u003cli\u003eGlutamate\u003c\/li\u003e\n\u003cli\u003eSerotonin\u003c\/li\u003e\n\u003cli\u003eTyrosine\u003c\/li\u003e\n\u003cli\u003eTryptophan\u003c\/li\u003e\n\u003cli\u003eKynurenine\u003c\/li\u003e\n\u003cli\u003eKynurenic Acid\u003c\/li\u003e\n\u003cli\u003e3-Hydroxykynurenine\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eHow this test may help:\u003c\/strong\u003e These urinary compounds, precursors and metabolites provide additional laboratory information for a review of concentration concerns. Daily hormone and MT6s profiles add context when brain fog occurs alongside disturbed sleep or changing energy levels.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eLow Motivation\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eReduced drive, lack of enthusiasm, procrastination or loss of interest in activities can affect your work and personal life.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMarkers assessed include:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eDopamine\u003c\/li\u003e\n\u003cli\u003eDOPAC\u003c\/li\u003e\n\u003cli\u003eHVA\u003c\/li\u003e\n\u003cli\u003ePEA\u003c\/li\u003e\n\u003cli\u003eTyrosine\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eHow this test may help:\u003c\/strong\u003e Dopamine is measured alongside its related metabolites and the precursor tyrosine. These findings provide a broader set of laboratory information to discuss when low motivation overlaps with mood, sleep or energy concerns.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eDifficulty Coping With Stress or Switching Off\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eSome people feel unable to unwind after stressful situations or remain mentally and physically “switched on” long after an event has passed.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMarkers assessed include:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eCortisol (4 measurements)\u003c\/li\u003e\n\u003cli\u003eCortisone (4 measurements)\u003c\/li\u003e\n\u003cli\u003eNorepinephrine (5 measurements)\u003c\/li\u003e\n\u003cli\u003eEpinephrine (5 measurements)\u003c\/li\u003e\n\u003cli\u003eGABA\u003c\/li\u003e\n\u003cli\u003eSerotonin\u003c\/li\u003e\n\u003cli\u003eGlutamate\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eHow this test may help:\u003c\/strong\u003e If you feel constantly switched on or struggle to unwind, the timed cortisol, cortisone, norepinephrine and epinephrine results provide measured daily patterns to review alongside when your symptoms occur. This adds useful information to a discussion about stress, sleep and your daily routine.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eWhy Is This Profile Different?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eU-343 combines:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eThe Advanced 26-marker urinary neurotransmitter profile, including creatinine\u003c\/li\u003e\n\u003cli\u003eNeurotransmitter metabolites and amino acid precursors such as tryptophan and tyrosine\u003c\/li\u003e\n\u003cli\u003eSelected tryptophan-kynurenine pathway markers\u003c\/li\u003e\n\u003cli\u003eFour timed urinary free cortisol measurements\u003c\/li\u003e\n\u003cli\u003eFour timed urinary free cortisone measurements\u003c\/li\u003e\n\u003cli\u003eFour timed urinary melatonin-metabolite (MT6s) measurements\u003c\/li\u003e\n\u003cli\u003eAdditional timed norepinephrine and epinephrine measurements\u003c\/li\u003e\n\u003cli\u003eAdditional creatinine measurements for urine concentration correction\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eParent neurotransmitters are measured alongside related metabolites, including dopamine with DOPAC and HVA, serotonin with 5-HIAA, and histamine with N-methylhistamine. Reviewing related compounds together provides a broader biochemical picture than considering individual results alone.\u003c\/p\u003e\n\u003cp\u003eCompared with the \u003ca href=\"https:\/\/hormonelab.co.uk\/products\/neurotransmitter-dried-urine-hormone-test\"\u003e42-marker U-342 panel\u003c\/a\u003e, U-343 adds four further measurements each of norepinephrine and epinephrine, increasing the total to 50. Both kits use four timed dried urine collections.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eWhy Test Neurotransmitters and Daily Hormone Patterns Together?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eThe panels provide different but complementary sets of laboratory information. The neurotransmitter profile measures selected urinary compounds, precursors and metabolites. The daily profile adds timed glucocorticoid, melatonin-metabolite and catecholamine measurements.\u003c\/p\u003e\n\u003cp\u003eReviewing these together provides several areas of information within one report, particularly useful for discussion when mood or concentration concerns occur alongside sleep, energy and stress concerns.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eWhat Are Neurotransmitters and the Hormones Included in This Panel?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eNeurotransmitters are chemical messengers that help nerve cells communicate. They are involved in mood, attention, movement, sleep and stress responses. This kit measures selected neurotransmitters and related compounds excreted in urine.\u003c\/p\u003e\n\u003cp\u003eCortisol is involved in the body’s stress response and daily rhythms. Cortisone provides related information about glucocorticoid metabolism. MT6s is the main urinary breakdown product of melatonin. Norepinephrine and epinephrine have roles in nervous-system signalling and the body’s stress response.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eChoosing Between Related Panels\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eThe \u003ca href=\"https:\/\/hormonelab.co.uk\/products\/neurotransmitter-testing-neuro-advanced-profile\"\u003eAdvanced 26-marker kit\u003c\/a\u003e provides the urinary neurotransmitter profile. The \u003ca href=\"https:\/\/hormonelab.co.uk\/products\/neurotransmitter-dried-urine-hormone-test\"\u003e42-marker U-342 kit\u003c\/a\u003e adds timed cortisol, cortisone and MT6s. U-343 further extends this combination with timed norepinephrine and epinephrine measurements.\u003c\/p\u003e\n\u003cp\u003eFor a combined urinary profile with saliva hormones, consider the \u003ca href=\"https:\/\/hormonelab.co.uk\/products\/advanced-neurotransmitter-hormone-test-i\"\u003e49-marker SU-841 kit\u003c\/a\u003e or the \u003ca href=\"https:\/\/hormonelab.co.uk\/products\/elite-neurotransmitter-saliva-hormone-test\"\u003e57-marker Elite kit\u003c\/a\u003e. The Elite kit combines seven saliva hormone measurements with the extended U-343 urinary profile.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eDried Urine Sample Collection Instructions\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eCollect four timed dried urine samples using the supplied materials.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBefore You Begin\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eRead the instructions supplied with your kit. Record all current medications, supplements and hormone treatments on the Test Requisition Form.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eChoosing Your Collection Day\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMen and children:\u003c\/strong\u003e Collect on any day of the month.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWomen who do not menstruate, including postmenopausal women:\u003c\/strong\u003e Collect on any day of the month.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWomen with regular periods:\u003c\/strong\u003e Choose a non-bleeding day. This urine-only test does not require collection on a specific day of your menstrual cycle.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWomen with irregular or infrequent periods:\u003c\/strong\u003e Collect on any non-bleeding day.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAvoid collecting during menstruation or whenever blood may be present in your urine.\u003c\/strong\u003e If you use hormone treatments, also follow the guidance below.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhen to Collect\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAll groups should collect samples at the following four times:\u003c\/p\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cstrong\u003eCollection Time\u003c\/strong\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e1\u003c\/td\u003e\n\u003ctd\u003eYour first urination immediately upon waking\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e2\u003c\/td\u003e\n\u003ctd\u003eYour second urination, approximately two hours after the first collection\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e3\u003c\/td\u003e\n\u003ctd\u003eJust before dinner\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e4\u003c\/td\u003e\n\u003ctd\u003eJust before bedtime\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eBefore your first collection, do not eat, drink anything other than water, or take vitamins or supplements. Follow your healthcare provider’s advice about medication timing; do not stop prescribed medication without their advice.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLimit fluid intake to no more than approximately 240 ml (8 oz) during the hour before each collection\u003c\/strong\u003e to avoid diluting your sample.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow to Collect Each Sample\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eRemove a collection card from its bag. Write your name, collection date and time on the card before collecting.\u003c\/li\u003e\n\u003cli\u003eOpen the cover and fold it away from the filter paper. Avoid touching the filter paper.\u003c\/li\u003e\n\u003cli\u003eFully saturate the filter paper by urinating directly onto it, or collect urine in a clean cup and dip the paper up to the top black dashed line.\u003c\/li\u003e\n\u003cli\u003eHang or tape the card somewhere secure to dry. Ensure the wet filter paper does not touch anything.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAllow the sample to dry completely for at least six hours.\u003c\/strong\u003e Once completely dry, refold the card, place it in its bag and seal it. Do not leave samples outside the bag for longer than 24 hours.\u003c\/li\u003e\n\u003cli\u003eRepeat these steps for each collection time.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eIf You Use Hormone Treatments\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eRecord all hormone treatments on your Test Requisition Form. Follow the hormone-use instructions supplied with your kit and your healthcare provider’s advice. Do not stop prescribed hormone treatment without their advice.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMorning hormones:\u003c\/strong\u003e Take or apply your usual morning dose after the first urine collection. Wash your hands thoroughly afterwards, especially after applying topical hormones.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNighttime hormones:\u003c\/strong\u003e Collect your bedtime sample before taking or applying your nighttime dose.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVaginal hormones:\u003c\/strong\u003e The laboratory’s instructions advise avoiding vaginal hormone use during the collection day until after the final urine sample. Discuss timing with your healthcare provider if needed.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eIf You Miss a Collection\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCollect the missed sample at the same time the following day. For example, collect a missed evening sample the following evening. Record the actual collection date and time on both the card and the Test Requisition Form, then follow the same drying and sealing instructions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReturning Your Samples\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eComplete the Test Requisition Form in full. Place it, any additional paperwork and all sealed, completely dry samples into the test kit box. Pack and return the kit according to the return instructions provided.\u003c\/p\u003e\n\u003cp\u003eA return envelope is provided with your kit. It is not prepaid; customers are responsible for return postage to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImportant:\u003c\/strong\u003e Urine samples that are wet, unsealed, excessively diluted or more than 30 days old will not be processed.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCollection Instructions:\u003c\/strong\u003e \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Saliva_Dried_Urine_Collection_Instructions.pdf?v=1785413203\"\u003eView dried urine collection instructions\u003c\/a\u003e\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eAdvanced LC-MS Technology\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eThe panel uses Liquid Chromatography Mass Spectrometry, or LC-MS, to analyse its urinary markers. Specialist laboratory interpretation accompanies the results.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eConvenient At-Home Collection\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eCollect four timed dried urine samples using the supplied filter cards. No blood draw or clinic visit is required. Allow the cards to dry fully before sealing and returning them according to the kit instructions.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eHow the Test Works\u003c\/strong\u003e\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit and receive the collection materials.\u003c\/li\u003e\n\u003cli\u003eCollect four timed dried urine samples according to the supplied timetable.\u003c\/li\u003e\n\u003cli\u003eDry, package and return your samples using the provided instructions.\u003c\/li\u003e\n\u003cli\u003eReceive your results by email, normally within 3–5 working days after the laboratory receives your samples.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003e\u003cstrong\u003eWhat You Receive With Your Results\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eYour report covers the panel’s 50 measurements, with numerical values, laboratory reference ranges, graphical daily profiles and specialist laboratory interpretation.\u003c\/p\u003e\n\u003cp\u003eShare the report with your practitioner to review the findings alongside your symptoms and routine. Keeping a note of sleep, energy and stress concerns on your collection day can help make that discussion more focused.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eKit Fees, Postage and Validity\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eLaboratory analysis and specialist interpretation are included. A return envelope is provided with your kit. It is not prepaid; customers are responsible for return postage to the laboratory. Use the kit within 12 months of purchase.\u003c\/p\u003e\n\u003cp\u003eFollow the preparation instructions and record medicines, supplements and hormone treatments on your requisition form.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eAbout ZRT Laboratory\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e, a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePioneers of at-home dried urine neurotransmitter and hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardisation (HoSt) Program\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003eRigorous internal and external quality assurance programmes\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eHormone Lab UK (Testfield UK Ltd) is the official UK test provider for ZRT Laboratory. All samples are analysed by ZRT Laboratory, a CLIA-certified laboratory with over 25 years of experience in hormone, neurotransmitter, and wellness testing.\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eFrequently Asked Questions\u003c\/strong\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eHow can this test help when sleep, mood and energy concerns overlap?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eIt combines urinary neurotransmitter-related results with timed cortisol, cortisone, MT6s, norepinephrine and epinephrine profiles. This gives your practitioner several sets of findings to review in one report and helps you prepare a focused discussion about next steps.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eWhat do the additional adrenaline-related measurements add?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eAdditional timed norepinephrine and epinephrine results extend the daily urinary profile. These provide measured patterns to discuss alongside the times you feel wired, tense, tired or more alert.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eHow can the results support a discussion about sleep?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eTimed MT6s results provide information about urinary melatonin metabolism. Reviewing these with cortisol, cortisone and neurotransmitter-related measurements adds laboratory information to your sleep diary and routine.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eCan the report be useful when my energy changes during the day?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eTimed hormone and adrenaline-related results provide daily patterns to review alongside when you feel tired or more alert. The neurotransmitter profile adds information when energy concerns overlap with brain fog, mood changes or low motivation.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eWhy measure cortisol and cortisone together?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eThey provide related but different urinary glucocorticoid measurements. Reviewing both timed profiles adds context about measured cortisol and cortisone levels across the collection day.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eWhat is MT6s?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e6-Sulfatoxymelatonin, or MT6s, is the main urinary metabolite of melatonin. Its timed measurements provide information relevant to melatonin metabolism and sleep-wake patterns.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eHow is the 50-measurement total calculated?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eIt includes the Advanced 26-marker profile, 12 timed cortisol\/cortisone\/MT6s measurements, four additional norepinephrine measurements, four additional epinephrine measurements and four additional creatinine measurements.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eWhy are norepinephrine and epinephrine listed in both tables?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eEach appears once in the Advanced profile and has four additional measurements in the combined daily profile, giving five reported measurements of each. Collection requires four timed urine samples.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eWhy is creatinine included?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eCreatinine helps account for differences in urine concentration when interpreting the results.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eHow many samples do I collect?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eFour dried urine samples: your first urination upon waking, your second approximately two hours later, before dinner and before bedtime.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eWhich panel adds saliva hormones to this urinary combination?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eThe \u003ca href=\"https:\/\/hormonelab.co.uk\/products\/elite-neurotransmitter-saliva-hormone-test\"\u003e57-marker Elite kit\u003c\/a\u003e adds seven saliva hormone measurements to the extended U-343 urinary profile. The \u003ca href=\"https:\/\/hormonelab.co.uk\/products\/advanced-neurotransmitter-hormone-test-i\"\u003e49-marker SU-841 kit\u003c\/a\u003e combines seven saliva hormones with the U-342 urinary profile.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eIs this test suitable for children and adults?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eThe dried urine collection method is non-invasive and suitable for children and adults. \u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eDo I need to visit a clinic?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eNo. Collect Sample At Home: No Clinic Visit Required. Use the supplied collection cards and follow the drying and return instructions.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eWhat if I take medicines, supplements or hormone treatments?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eRecord them on the requisition form and follow the kit instructions. Do not change prescribed treatment without healthcare provider advice.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eWhat do I receive with my results?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eNumerical values, laboratory reference ranges, graphical daily profiles and specialist laboratory interpretation covering the panel’s 50 measurements.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eHow can I use my report?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eShare it with your practitioner alongside your symptoms, collection times, medicines and supplements. Use the interpretation to prepare questions about the findings and discuss appropriate further assessment or nutrition, lifestyle and wellbeing steps.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eWhen will I receive my results?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eResults are normally emailed within 3–5 working days after the laboratory receives your samples.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eAre laboratory fees included?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eYes. Laboratory analysis and specialist interpretation are included.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eIs the return envelope prepaid?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eNo. A return envelope is supplied, but customers pay return postage to the laboratory.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eUse the kit within 12 months of purchase.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eRelated Neurotransmitter and Hormone Test Panels\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/hormonelab.co.uk\/products\/neurotransmitter-testing-neuro-advanced-profile\"\u003eAdvanced Neurotransmitter Test Kit | 26 Markers\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/hormonelab.co.uk\/products\/neurotransmitter-dried-urine-hormone-test\"\u003eAdvanced Neurotransmitter \u0026amp; Diurnal Hormone Test | 42 Markers\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/hormonelab.co.uk\/products\/advanced-neurotransmitter-hormone-test-i\"\u003eAdvanced Neurotransmitter \u0026amp; Hormone Test I | 49 Markers\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/hormonelab.co.uk\/products\/elite-neurotransmitter-saliva-hormone-test\"\u003eElite Neurotransmitters \u0026amp; Saliva Hormone Test | 57 Markers\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/hormonelab.co.uk\/products\/neurotransmitter-saliva-hormone-test-ii\"\u003eNeurotransmitter \u0026amp; Saliva Hormone Test II | 36 Markers\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":32496978034774,"sku":"0082","price":559.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Neurotransmitters_Test.webp?v=1785073865"},{"product_id":"advanced-sleep-hormone-test-udh-ii","title":"Advanced Sleep Hormone Test (UDH II) | 24 Markers","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e U-322 Advanced Sleep Hormone Test (UDH II) | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Dried Urine (4 collections) | \u003cstrong\u003eTechnology:\u003c\/strong\u003e Advanced LCMS analysis with specialist laboratory interpretation included | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory (CLIA-certified) | \u003cstrong\u003eTest Result:\u003c\/strong\u003e in 3-5 working days | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eAdvanced Sleep Hormone Test (UDH II): Sleep Balance + LCMS Urine Diurnal Hormones Profile (UDH II) + Diurnal Norepinephrine \u0026amp; Epinephrine\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eLCMS Urine Diurnal Hormones Profile (UDH II) - Sleep Balance Profile + Diurnal Norepinephrine \u0026amp; Epinephrine offers additional insights into the neuroendocrine factors influencing sleep and wakefulness. In combination with the Sleep Balance Profile Test, this add-on provides a more comprehensive assessment of sleep-related issues. The Sleep Balance Profile\u003cstrong\u003e \u003c\/strong\u003eTest \u003cstrong\u003eaccurately measures the following 24 hormones: \u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFree Cortisol (FCx4) 4 Times a day,\u003c\/li\u003e\n\u003cli\u003eFree Cortisone (FCnx4) 4 Times a day,\u003c\/li\u003e\n\u003cli\u003eCreatinine (Crtnx4) 4 Times a day,\u003c\/li\u003e\n\u003cli\u003eMelatonin Metabolite 6  Sulfatoxymelatonin (MT6sx4) x 4 times a day,\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdd on:\u003c\/strong\u003e Norepinepherine (NEx4) 4 Times a day,\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdd on:\u003c\/strong\u003e Epinephrine (Epix4) 4 Times a day.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTest Method: \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eMass spectrometry (LCMS)–\u003c\/em\u003e\u003c\/strong\u003e\u003cem\u003e utilizes different sample preparations to measure analytes, or fragments of analytes, via a mass\/charge ratio. Gold standard for high sensitivity\/specificity, extended linear range, and complex hormone analysis. Slow adoption due to cost of instrumentation and need for highly trained staff.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca class=\"text-link\" href=\"mailto:info@hormonelab.co.uk\" target=\"_blank\" rel=\"nofollow noopener\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours with a suggestion.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cu\u003eKey Features\u003c\/u\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSleep Quality Assessment: The Sleep Balance Profile Test provides insights into various aspects of sleep quality, including the measurement of melatonin, a hormone involved in regulating the sleep-wake cycle. By assessing melatonin levels, the test helps evaluate the effectiveness of the body's natural sleep-inducing mechanisms.\u003c\/li\u003e\n\u003cli\u003eSleep Disorder Identification: The Sleep Balance Profile Test aids in identifying potential underlying causes of sleep disorders such as insomnia, delayed sleep phase syndrome, and circadian rhythm disorders. By evaluating hormone levels and circadian rhythm markers it helps pinpoint specific dysfunctions that may contribute to sleep disturbances.\u003c\/li\u003e\n\u003cli\u003eHormonal Evaluation: The Sleep Balance Profile Test measures the levels of key hormones involved in sleep regulation, including melatonin, cortisol, and cortisone. These hormones play a crucial role in the sleep-wake cycle, circadian rhythm, and overall sleep quality.\u003c\/li\u003e\n\u003cli\u003eDried Urine Spot (DUS) Collection: The test utilises dried urine spot collection, which offers convenience and ease of use. Dried urine samples can be collected at home, making it a convenient option for individuals to monitor their sleep-related hormone levels.\u003c\/li\u003e\n\u003cli\u003eMelatonin Assessment: Melatonin is a hormone produced by the pineal gland that regulates the sleep-wake cycle. This test evaluates melatonin levels, providing insights into the body's natural production of this sleep hormone.\u003c\/li\u003e\n\u003cli\u003eCortisol and Cortisone Measurement: Cortisol and cortisone are stress hormones that can impact sleep quality. The test assesses these hormone levels, helping to identify any imbalances that may contribute to sleep disturbances.\u003c\/li\u003e\n\u003cli\u003eCircadian Rhythm Evaluation: The Sleep Balance Profile Test provides information about the body's circadian rhythm, which is crucial for maintaining a healthy sleep pattern. Evaluating the levels of melatonin and cortisol in relation to the individual's sleep-wake cycle helps to assess the synchronisation between hormones and sleep patterns.\u003c\/li\u003e\n\u003cli\u003eComprehensive Sleep Assessment: By examining multiple hormone levels involved in sleep regulation, the Sleep Balance Profile Test offers a comprehensive evaluation of sleep health. It provides a more complete picture of the hormonal factors that may be influencing an individual's sleep quality and patterns.\u003c\/li\u003e\n\u003cli\u003eTreatment Monitoring: The Sleep Balance Profile Test can be utilized to monitor the effectiveness of interventions and treatment plans for sleep-related issues. By retesting hormone levels and circadian markers, healthcare professionals can assess progress and make adjustments to the treatment approach as needed.\u003c\/li\u003e\n\u003cli\u003ePersonalised Treatment Approach: The test results can help healthcare professionals develop personalised treatment plans for individuals experiencing sleep disturbances. By identifying hormone imbalances, healthcare providers can recommend targeted interventions, including lifestyle modifications, dietary changes, and supplementation, to optimise sleep health.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTest Result: \u003c\/strong\u003eYou will receive your test result 3-5 working days after the laboratory receives your sample. You will see your hormone levels in graphics and numbers on your test results. In the comments, you will also see laboratory comments by Hormone Specialist PhD Dr: you will find Dr analysis of your hormone levels and what to do next.\u003c\/li\u003e\n\u003cli\u003eClick to see \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Sleep-balance-profile_Sample_Report.pdf?v=1657974970\" target=\"_blank\" rel=\"noopener noreferrer nofollow\"\u003e\u003cstrong\u003eSleep Balance Sample Report\u003c\/strong\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eCollect samples from the comfort of your home and post them to our lab.\u003c\/li\u003e\n\u003cli\u003eThe test must be used within 12 months after the purchase date.\u003c\/li\u003e\n\u003cli\u003eThe test kit includes a laboratory fee: no additional laboratory cost or tax.\u003c\/li\u003e\n\u003cli\u003eCustomers are responsible for shipping their samples to the laboratory. \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cu\u003eThe Test Kit pack includes\u003c\/u\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTest Requisition Form includes Symptom Checklist\u003c\/li\u003e\n\u003cli\u003eRequisition Form to complete, including your personal and medical history\u003c\/li\u003e\n\u003cli\u003eContains collection instructions\u003c\/li\u003e\n\u003cli\u003eSample Cards for collecting a dried urine sample\u003c\/li\u003e\n\u003cli\u003eInstructions on How to Use Collection Kit\u003c\/li\u003e\n\u003cli\u003eReturn Envelope\u003c\/li\u003e\n\u003cli\u003eShipping instruction\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cu\u003eAre You Familiar With Following Questions?\u003c\/u\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePeople who have difficulty sleeping may have various questions related to their insomnia or sleep disturbances. Here are some common questions that individuals with sleep issues may ask:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eWhy am I having trouble falling asleep?\u003c\/li\u003e\n\u003cli\u003eWhat could be causing my frequent waking during the night?\u003c\/li\u003e\n\u003cli\u003eHow can I improve the quality of my sleep?\u003c\/li\u003e\n\u003cli\u003eAre there any lifestyle changes I can make to promote better sleep?\u003c\/li\u003e\n\u003cli\u003eWhat are some effective strategies for managing racing thoughts or an overactive mind at night?\u003c\/li\u003e\n\u003cli\u003eIs it normal to feel anxious or stressed before bed, and how can I reduce these feelings?\u003c\/li\u003e\n\u003cli\u003eAre there any natural remedies or supplements that may help me sleep better?\u003c\/li\u003e\n\u003cli\u003eWhen should I seek professional help for my sleep problems?\u003c\/li\u003e\n\u003cli\u003eWhat is the recommended amount of sleep for someone my age, and how can I ensure I'm getting enough?\u003c\/li\u003e\n\u003cli\u003eCan certain medications or medical conditions be affecting my sleep?\u003c\/li\u003e\n\u003cli\u003eHow can I establish a consistent sleep schedule and routine?\u003c\/li\u003e\n\u003cli\u003eWhat are some relaxation techniques or practices I can try before bed to promote sleep?\u003c\/li\u003e\n\u003cli\u003eAre there any underlying sleep disorders that I should be aware of and get evaluated for?\u003c\/li\u003e\n\u003cli\u003eHow can I address and overcome insomnia or sleep anxiety?\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIt's important to note that sleep concerns can be complex, and individual experiences may vary. Our Sleep Balance Test Kit might answer your questions. After receiving your test result we recommend consulting with a healthcare professional, such as a sleep specialist or doctor, can provide personalised advice and guidance based on an individual's specific sleep difficulties.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cu\u003eAdvantages of Sleep Balance Profile Test\u003c\/u\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eHere are some potential benefits of the Sleep Balance Test in dried urine spot:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNo more 2:00 am wake-ups-more accurate results\u003c\/li\u003e\n\u003cli\u003eMeasures hormones at 4-time points\u003c\/li\u003e\n\u003cli\u003eProvide a true 24-hour sleep-wake pattern\u003c\/li\u003e\n\u003cli\u003eNo jug urine collection. Collect your sample through Dried Urine Spot Sample Card and post it to our lab.\u003c\/li\u003e\n\u003cli\u003eAssessment of hormone levels: The test can provide insights into hormone imbalances that may be affecting sleep patterns, such as cortisol (stress hormone), melatonin (sleep-regulating hormone), and other hormones involved in the sleep-wake cycle.\u003c\/li\u003e\n\u003cli\u003eEvaluation of circadian rhythm: The test can assess the timing and balance of hormone secretion throughout the day and night, providing information about circadian rhythm disruptions or irregularities.\u003c\/li\u003e\n\u003cli\u003ePersonalised treatment approach: The results of the test can help healthcare providers tailor treatment plans based on individual hormone profiles. This may include hormone replacement therapy, lifestyle modifications, or targeted interventions to address specific imbalances.\u003c\/li\u003e\n\u003cli\u003eIdentification of underlying causes: The Sleep Balance Test can help identify potential underlying causes of sleep disturbances, such as hormonal imbalances, chronic stress, or disruptions in the body's natural sleep-wake cycle.\u003c\/li\u003e\n\u003cli\u003eMonitoring treatment progress: For individuals undergoing hormone therapy or other interventions to improve sleep quality, the Sleep Balance Test can be used to track changes in hormone levels over time and assess the effectiveness of the treatment.\u003c\/li\u003e\n\u003cli\u003eImproved sleep management: By gaining a better understanding of hormone imbalances and circadian rhythm disruptions, individuals can make informed decisions about sleep hygiene, lifestyle adjustments, and potential interventions to optimise their sleep patterns.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cu\u003eBenefits of Add On Diurnal Norepinephrine \u0026amp; Epinephrine with Sleep Balance Profile \u003c\/u\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe Diurnal Norepinephrine \u0026amp; Epinephrine with Sleep Balance Test offers several benefits in evaluating and managing sleep-related issues, as well as assessing the diurnal patterns of norepinephrine and epinephrine hormones. Here are the potential benefits of this comprehensive testing approach:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSleep-Wake Cycle Assessment: The test allows for the evaluation of the diurnal patterns of norepinephrine and epinephrine hormones, which are involved in regulating the body's arousal and wakefulness. By assessing the levels of these hormones throughout the day, it provides insights into their impact on the sleep-wake cycle and overall sleep quality.\u003c\/li\u003e\n\u003cli\u003eStress Response Evaluation: Norepinephrine and epinephrine are key hormones involved in the body's stress response. By measuring their levels and patterns, the test helps assess the individual's stress adaptation and identify any dysregulation that may impact sleep quality and overall well-being.\u003c\/li\u003e\n\u003cli\u003eCircadian Rhythm Assessment: The diurnal testing of norepinephrine and epinephrine provides valuable information about their natural fluctuations throughout the day, contributing to the evaluation of the individual's circadian rhythm function. Disruptions in circadian rhythm can significantly affect sleep patterns and overall sleep quality.\u003c\/li\u003e\n\u003cli\u003eSleep Disorder Identification: The test aids in identifying potential underlying causes of sleep disorders such as insomnia, sleep apnea, and circadian rhythm disorders. By evaluating the diurnal patterns of norepinephrine and epinephrine, it helps pinpoint specific dysfunctions that may contribute to sleep disturbances and guide appropriate interventions.\u003c\/li\u003e\n\u003cli\u003ePersonalized Treatment Approach: The comprehensive analysis provided by the Diurnal Norepinephrine \u0026amp; Epinephrine with Sleep Balance Test allows healthcare professionals to develop personalized treatment plans based on individual sleep-related issues. By identifying dysregulations in norepinephrine and epinephrine levels, targeted interventions can be recommended, including stress management techniques, lifestyle modifications, and other therapeutic strategies to optimize sleep health.\u003c\/li\u003e\n\u003cli\u003eTreatment Monitoring: The test can be utilized to monitor the effectiveness of interventions and treatment plans for sleep-related issues. By retesting norepinephrine and epinephrine levels and assessing their diurnal patterns, healthcare professionals can evaluate progress and make adjustments to the treatment approach as needed.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBy combining the assessment of diurnal norepinephrine and epinephrine levels with sleep balance testing, individuals and healthcare professionals can gain valuable insights into the interaction between stress hormones, circadian rhythm, and sleep quality. This comprehensive analysis allows for targeted interventions, personalized treatment plans, and improved management of sleep-related issues.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cu\u003eLosing Sleep? It Could Be Hormones\u003c\/u\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eLack of sleep, also known as sleep deprivation, can manifest with various symptoms. Here are some common symptoms associated with insufficient sleep:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFatigue: Feeling excessively tired and lacking energy throughout the day.\u003c\/li\u003e\n\u003cli\u003eDaytime sleepiness: Experiencing a strong urge to sleep or dozing off during waking hours.\u003c\/li\u003e\n\u003cli\u003eDifficulty concentrating: Finding it challenging to stay focused, pay attention, and retain information.\u003c\/li\u003e\n\u003cli\u003ePoor memory: Having difficulties with recalling details or events.\u003c\/li\u003e\n\u003cli\u003eIrritability: Feeling easily agitated, short-tempered, or more prone to mood swings.\u003c\/li\u003e\n\u003cli\u003eMood changes: Experiencing changes in mood, such as increased irritability, anxiety, or depression.\u003c\/li\u003e\n\u003cli\u003eReduced motivation: Experiencing a decline in enthusiasm or lack of drive to engage in activities.\u003c\/li\u003e\n\u003cli\u003eImpaired judgment: Making poor decisions or having difficulty assessing risks accurately.\u003c\/li\u003e\n\u003cli\u003eIncreased appetite: Feeling hungrier than usual, especially craving high-calorie, sugary foods.\u003c\/li\u003e\n\u003cli\u003eWeakened immune function: Having a higher susceptibility to illnesses and infections.\u003c\/li\u003e\n\u003cli\u003eReduced libido: Experiencing a decrease in sexual desire or interest.\u003c\/li\u003e\n\u003cli\u003eHeadaches: Developing frequent headaches or migraines.\u003c\/li\u003e\n\u003cli\u003eMuscle aches and weakness: Experiencing muscle fatigue, weakness, or general discomfort.\u003c\/li\u003e\n\u003cli\u003eBlurred vision: Having temporary vision problems or difficulty focusing on objects.\u003c\/li\u003e\n\u003cli\u003eIncreased risk of accidents: Being more prone to accidents or errors due to impaired cognitive functioning and slower reaction times.\u003c\/li\u003e\n\u003cli\u003eCan’t get to sleep or stay asleep in the night,\u003c\/li\u003e\n\u003cli\u003eFrequent or early waking,\u003c\/li\u003e\n\u003cli\u003eWeight gain.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIt's important to note that the effects of sleep deprivation can vary from person to person, and some individuals may experience additional or different symptoms. If two or more of these symptoms persist, Sleep Balance testing can identify whether it’s a hormonal imbalance. Simple testing can release whether your hormones are the hidden barrier to your restful sleep.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cu\u003eHidden Barriers to Restful Sleep\u003c\/u\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDue to life and work lifestyles, many people suffer from some degree of insomnia; it’s surprising that many are still unaware of the connection between hormones and sleep. Several hormones are key to the sleep-wake cycle, and an imbalance of these levels can sabotage slumber night after a sleepless night.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cu\u003eHormones \u0026amp; Your Sleep\u003c\/u\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eMany adults are losing sleep because of stress – the constant companion of modern life. Cortisol is the hormone released by our bodies in response to stress, and chronically elevated levels are known to impair our ability to sleep. Additionally, the gradual decline in the production of the sleep hormone melatonin as we age triggers imbalances directly related to sleep.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cu\u003eUnderstanding The Sleep - Wake Cycle.\u003c\/u\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIn a perfect world, the master stress hormone cortisol should be in sync with the master sleep hormone melatonin. Each hormone counter-balances the other in a precise rhythm – when cortisol is high, melatonin should be low, and when melatonin is high, cortisol should be low. When this balance is upset, we find ourselves longing for sleep that never comes.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cu\u003eThe Downside of Chronic Sleep Loss\u003c\/u\u003e\u003c\/strong\u003e\u003cbr\u003eThe benefits of adequate sleep cannot be overstated. According to the Department of Health \u0026amp; Human Services, over a third of adults report daytime sleepiness so severe it interferes with work, decision making and social functioning. In fact, depression, obesity and diabetes are just three of the long-term consequences of sleep deprivation – defined as six or fewer hours per night.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"ZRT Lab","offers":[{"title":"Default Title","offer_id":39941254119510,"sku":"10002","price":319.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Sleep-Hormone-Profile-II.webp?v=1792667515"},{"product_id":"neurotransmitter-toxic-elements-test","title":"Advanced Neurotransmitter \u0026 Toxic Elements Test | 34 Markers","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e U-325 + U-327 Advanced Neurotransmitter \u0026amp; Toxic Elements Test | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Dried Urine, 4 Timed Collections | \u003cstrong\u003eTechnology:\u003c\/strong\u003e LC-MS and ICP-MS with specialist laboratory interpretation included | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory (CLIA-certified) | \u003cstrong\u003eTest Result:\u003c\/strong\u003e Normally 3–5 working days after the laboratory receives your samples | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eNeurotransmitters and Toxic Elements — Measured Together in One Dried Urine Test\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eThis combined kit brings together the Advanced \u003cstrong\u003e26-marker urinary neurotransmitter profile\u003c\/strong\u003e and a \u003cstrong\u003etoxic and essential elements panel\u003c\/strong\u003e, using four timed dried urine collections at home.\u003c\/p\u003e\n\u003cp\u003eThe two panels provide urinary measurements for discussion with your healthcare practitioner when concerns about mood, sleep, energy or concentration overlap with questions about selected element exposure or intake.\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eWhat This Test Measures (34 Markers)\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eThe listed 34-marker total comprises 26 entries in the neurotransmitter profile and eight entries in the elements panel. Creatinine appears in both panels to account for urine concentration, so this does not mean 34 different substances.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eDried Urine — 26 Neurotransmitter-Related Markers (LC-MS)\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eTryptophan (Trp)\u003c\/td\u003e\n\u003ctd\u003eSerotonin (5-HT)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e5-HIAA\u003c\/td\u003e\n\u003ctd\u003eGABA\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGlycine (Gly)\u003c\/td\u003e\n\u003ctd\u003eTaurine (Tau)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGlutamate (Glu)\u003c\/td\u003e\n\u003ctd\u003eGlutamine (Gln)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHistidine (His)\u003c\/td\u003e\n\u003ctd\u003eHistamine (HIST)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eN-Methylhistamine (N-MeHist)\u003c\/td\u003e\n\u003ctd\u003ePhenylethylamine (PEA)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTyrosine (Tyr)\u003c\/td\u003e\n\u003ctd\u003eTyramine (Tyra)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDopamine (DA)\u003c\/td\u003e\n\u003ctd\u003eDOPAC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHomovanillic Acid (HVA)\u003c\/td\u003e\n\u003ctd\u003eNorepinephrine (NE)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNormetanephrine (NMN)\u003c\/td\u003e\n\u003ctd\u003eEpinephrine (Epi)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVanillylmandelic Acid (VMA)\u003c\/td\u003e\n\u003ctd\u003eKynurenine (Kyn)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eKynurenic Acid (KynAc)\u003c\/td\u003e\n\u003ctd\u003e3-Hydroxykynurenine (3OHKyn)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eXanthurenic Acid (Xanth)\u003c\/td\u003e\n\u003ctd\u003eCreatinine (Crtn)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3\u003e\u003cstrong\u003eDried Urine — Toxic \u0026amp; Essential Elements Panel — 8 Entries (ICP-MS)\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cstrong\u003eIodine (I)\u003c\/strong\u003e — essential element involved in thyroid hormone production\u003c\/td\u003e\n\u003ctd\u003e\n\u003cstrong\u003eBromine (Br)\u003c\/strong\u003e — urinary element measurement for review alongside the other panel results\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cstrong\u003eSelenium (Se)\u003c\/strong\u003e — essential element involved in thyroid hormone metabolism and antioxidant functions\u003c\/td\u003e\n\u003ctd\u003e\n\u003cstrong\u003eArsenic (As)\u003c\/strong\u003e — toxic element measurement for review in the context of potential exposure\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cstrong\u003eMercury (Hg)\u003c\/strong\u003e — toxic element measurement for review in the context of potential exposure\u003c\/td\u003e\n\u003ctd\u003e\n\u003cstrong\u003eCadmium (Cd)\u003c\/strong\u003e — toxic element measurement for review in the context of potential exposure\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cstrong\u003eLithium (Li)\u003c\/strong\u003e — naturally occurring element; record lithium medication use on your requisition form\u003c\/td\u003e\n\u003ctd\u003e\n\u003cstrong\u003eCreatinine (Crtn)\u003c\/strong\u003e — urine concentration marker, not an element\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003e\u003cstrong\u003eNot Sure Which Test Is Right for You?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca class=\"text-link\" href=\"mailto:info@hormonelab.co.uk\" rel=\"nofollow\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours with a suggestion.\u003c\/p\u003e\n\u003cdiv\u003e\n\u003ch2\u003e\u003cstrong\u003eThe Benefit of Combining Both Profiles\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eMany symptoms do not have a single cause. A person experiencing fatigue, anxiety, poor sleep, low mood, or brain fog may have contributions from:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNeurotransmitter imbalances\u003c\/li\u003e\n\u003cli\u003eAltered neurotransmitter metabolism\u003c\/li\u003e\n\u003cli\u003eNutrient insufficiencies\u003c\/li\u003e\n\u003cli\u003eThyroid-related nutrient status\u003c\/li\u003e\n\u003cli\u003eEnvironmental element exposure\u003c\/li\u003e\n\u003cli\u003eMultiple overlapping biochemical factors\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBy assessing all of these areas together, this profile provides a more comprehensive overview than neurotransmitter testing or elemental testing alone, helping healthcare practitioners make more informed recommendations for further investigation, monitoring, nutrition, lifestyle modifications, or treatment planning.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch2\u003e\u003cstrong\u003eSymptoms and Exposure Concerns\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eThis combined Neurotransmitter and Toxic \u0026amp; Essential Elements Profile may be helpful for individuals experiencing persistent symptoms that may be influenced by neurotransmitter pathways, nutritional status, or environmental exposures.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003ePersistent Tiredness or Low Motivation\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eLow energy, reduced drive, fatigue, or lack of motivation can affect work performance, exercise tolerance, and quality of life.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow this test may help:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe profile assesses neurotransmitters involved in energy, alertness, reward, and motivation, including:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eDopamine (DA)\u003c\/li\u003e\n\u003cli\u003ePhenylethylamine (PEA)\u003c\/li\u003e\n\u003cli\u003eNorepinephrine (NE)\u003c\/li\u003e\n\u003cli\u003eEpinephrine (Epi)\u003c\/li\u003e\n\u003cli\u003eDOPAC\u003c\/li\u003e\n\u003cli\u003eHomovanillic Acid (HVA)\u003c\/li\u003e\n\u003cli\u003eTyrosine (Tyr)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe panel also includes iodine and selenium, which are essential nutrients involved in normal thyroid hormone production and metabolism.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eBrain Fog or Difficulty Concentrating\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003ePoor concentration, forgetfulness, reduced focus, and mental fatigue can have many possible causes.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow this test may help:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe profile measures neurotransmitter pathways involved in attention, mental performance, and cognitive function, including:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eDopamine (DA)\u003c\/li\u003e\n\u003cli\u003eNorepinephrine (NE)\u003c\/li\u003e\n\u003cli\u003eGlutamate (Glu)\u003c\/li\u003e\n\u003cli\u003eTyrosine (Tyr)\u003c\/li\u003e\n\u003cli\u003eTryptophan (Trp)\u003c\/li\u003e\n\u003cli\u003eKynurenine (Kyn)\u003c\/li\u003e\n\u003cli\u003eKynurenic Acid (KynAc)\u003c\/li\u003e\n\u003cli\u003e3-Hydroxykynurenine (3OHKyn)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThese results may help provide a broader assessment of pathways involved in focus and mental clarity.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eFeeling Anxious, Tense or Overwhelmed\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eSymptoms may include nervousness, excessive worry, feeling stressed, panic-like symptoms, or finding it difficult to relax.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow this test may help:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe profile evaluates neurotransmitters involved in both calming and stimulating nervous system activity, including:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eGABA\u003c\/li\u003e\n\u003cli\u003eGlycine\u003c\/li\u003e\n\u003cli\u003eTaurine\u003c\/li\u003e\n\u003cli\u003eGlutamate\u003c\/li\u003e\n\u003cli\u003eSerotonin (5-HT)\u003c\/li\u003e\n\u003cli\u003eNorepinephrine (NE)\u003c\/li\u003e\n\u003cli\u003eEpinephrine (Epi)\u003c\/li\u003e\n\u003cli\u003eNormetanephrine (NMN)\u003c\/li\u003e\n\u003cli\u003eVanillylmandelic Acid (VMA)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThis combination may help identify patterns within pathways involved in stress response and emotional regulation.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eLow Mood, Irritability or Mood Changes\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eChanges in mood can affect emotional wellbeing, motivation, relationships, and daily functioning.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow this test may help:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe profile assesses several pathways involved in mood regulation, including:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSerotonin (5-HT)\u003c\/li\u003e\n\u003cli\u003e5-HIAA\u003c\/li\u003e\n\u003cli\u003eDopamine (DA)\u003c\/li\u003e\n\u003cli\u003eDOPAC\u003c\/li\u003e\n\u003cli\u003eHomovanillic Acid (HVA)\u003c\/li\u003e\n\u003cli\u003eTryptophan (Trp)\u003c\/li\u003e\n\u003cli\u003ePhenylethylamine (PEA)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe inclusion of neurotransmitters, their metabolites, and precursor amino acids provides a broader view of neurotransmitter pathway activity.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eDifficulty Falling Asleep, Staying Asleep or Waking Refreshed\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eSleep quality is influenced by multiple neurotransmitter systems that regulate relaxation, wakefulness, and circadian rhythms.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow this test may help:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe profile measures:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eGABA\u003c\/li\u003e\n\u003cli\u003eGlycine\u003c\/li\u003e\n\u003cli\u003eTaurine\u003c\/li\u003e\n\u003cli\u003eGlutamate\u003c\/li\u003e\n\u003cli\u003eSerotonin (5-HT)\u003c\/li\u003e\n\u003cli\u003eHistamine (HIST)\u003c\/li\u003e\n\u003cli\u003eTryptophan (Trp)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThese markers may provide useful information when investigating pathways involved in sleep regulation and nervous system balance.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e\u003cstrong\u003eConcern About Exposure to Arsenic, Cadmium or Inorganic Mercury\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eSome individuals may wish to assess potential exposure due to occupational, environmental, dietary, or lifestyle factors.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow this test may help:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe Toxic \u0026amp; Essential Elements Panel measures:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eArsenic (As)\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eMercury (Hg)\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eCadmium (Cd)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThese measurements can be reviewed alongside symptoms, exposure history, and other laboratory findings as part of a wider health assessment.\u003c\/p\u003e\n\u003cp\u003eThe panel also includes:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIodine (I)\u003c\/strong\u003e – essential for normal thyroid hormone production\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSelenium (Se)\u003c\/strong\u003e – involved in thyroid hormone metabolism and antioxidant functions\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBromine (Br)\u003c\/strong\u003e – measured for review alongside other element results\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLithium (Li)\u003c\/strong\u003e – naturally occurring trace element\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003c\/div\u003e\n\u003ch2 data-pm-slice=\"1 1 []\"\u003e\u003cstrong\u003eHow This Test Can Help Guide Your Next Steps\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eIf you are struggling with tiredness, brain fog, mood changes or poor sleep, this profile provides additional information about your body’s chemistry to support a more personalised assessment.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eExplore pathways related to your symptoms\u003c\/strong\u003e\u003cbr\u003eThe test measures urinary markers related to serotonin, dopamine, GABA and other chemical messengers involved in mood, motivation, concentration, relaxation and sleep. Measuring their building blocks and breakdown products gives your healthcare professional a broader picture of how your body processes these substances.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReview relevant nutritional factors\u003c\/strong\u003e\u003cbr\u003eIodine and selenium measurements provide information about recent intake of nutrients that support normal thyroid function. Your results can guide a discussion about your diet, supplements and whether further nutritional or thyroid testing would be useful.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eInvestigate possible environmental exposure\u003c\/strong\u003e\u003cbr\u003eThe panel measures arsenic, cadmium and mercury in urine. These results can help your healthcare professional assess potential exposure and decide whether to investigate a source, arrange further testing or recommend ways to reduce exposure.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePlan appropriate next steps\u003c\/strong\u003e\u003cbr\u003eReviewed alongside your symptoms and health history, the findings can help guide further investigations and informed discussions about nutrition, lifestyle and care. They add information to your assessment rather than providing a diagnosis or identifying the cause of symptoms on their own.\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eHow It Works\u003c\/strong\u003e\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrder your kit\u003c\/strong\u003e — delivered directly to your door\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCollect four dried urine samples\u003c\/strong\u003e throughout the day using the provided collection strips\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePost your samples\u003c\/strong\u003e to the laboratory using the provided instructions\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReceive your results by email\u003c\/strong\u003e within \u003cstrong\u003e3–5 working days\u003c\/strong\u003e of the lab receiving your samples\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003e\u003cstrong\u003eWhat You Receive With Your Results\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll 34 panel entries in clear \u003cstrong\u003egraphics and easy-to-read values\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003eFull neurotransmitter pathway analysis including metabolites and precursors\u003c\/li\u003e\n\u003cli\u003eToxic and essential elements panel with reference ranges\u003c\/li\u003e\n\u003cli\u003eSpecialist PhD laboratory interpretation\u003c\/li\u003e\n\u003cli\u003eGuidance on what your results mean and recommended next steps\u003c\/li\u003e\n\u003cli\u003eLaboratory analysis for both panels included.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003ca title=\"Advanced Neurotransmitter Test Report\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/advanced-neurotransmitters_7b487e14-4f01-4507-8446-edb06192ccaf.pdf?v=1589397181\"\u003e\u003cstrong\u003eView Sample Neurotransmitter Report\u003c\/strong\u003e\u003c\/a\u003e | \u003ca title=\"Toxic and Essential Elements Test Sample Report\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/toxic-essential-elements-urine.pdf?v=1647865876\"\u003e\u003cstrong\u003eView Sample Toxic Elements Report\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eWhy We Use ZRT Laboratory\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e. ZRT uses both LC-MS and ICP-MS technology to provide clinical-grade accuracy from at-home dried urine samples.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eHormone Lab UK (Testfield UK Ltd) is the official UK test provider for ZRT Laboratory.\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eImportant Information\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eLaboratory analysis for both panels is included in the price\u003c\/li\u003e\n\u003cli\u003eA return envelope is supplied, but it is not prepaid. Customers pay return postage to the laboratory\u003c\/li\u003e\n\u003cli\u003eTest kit valid for 12 months from purchase date\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003e\u003cstrong\u003eDried Urine Sample Collection Instructions\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eCollect four timed dried urine samples using the supplied materials with your test kit.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBefore You Begin\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eRead sample collection and shipping instructions supplied with your kit. Record all current medications, supplements and hormone treatments on the Test Requisition Form.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eChoosing Your Collection Day\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMen and children:\u003c\/strong\u003e Collect on any day of the month.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWomen who do not menstruate, including postmenopausal women:\u003c\/strong\u003e Collect on any day of the month.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWomen with regular periods:\u003c\/strong\u003e Choose a non-bleeding day. This urine-only test does not require collection on a specific day of your menstrual cycle.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWomen with irregular or infrequent periods:\u003c\/strong\u003e Collect on any non-bleeding day.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAvoid collecting during menstruation or whenever blood may be present in your urine.\u003c\/strong\u003e If you use hormone treatments, also follow the guidance below.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhen to Collect\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAll groups should collect samples at the following four times:\u003c\/p\u003e\n\u003cdiv class=\"rte__table-wrapper\"\u003e\n\u003cdiv class=\"rte__table-wrapper\"\u003e\n\u003cdiv class=\"rte__table-wrapper\"\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cstrong\u003eCollection Time\u003c\/strong\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e1\u003c\/td\u003e\n\u003ctd\u003eYour first urination immediately upon waking\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e2\u003c\/td\u003e\n\u003ctd\u003eYour second urination, approximately two hours after the first collection\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e3\u003c\/td\u003e\n\u003ctd\u003eJust before dinner\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e4\u003c\/td\u003e\n\u003ctd\u003eJust before bedtime\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp\u003eBefore your first collection, do not eat, drink anything other than water, or take vitamins or supplements. Follow your healthcare provider’s advice about medication timing; do not stop prescribed medication without their advice.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLimit fluid intake to no more than approximately 240 ml (8 oz) during the hour before each collection\u003c\/strong\u003e to avoid diluting your sample.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow to Collect Each Sample\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eRemove a collection card from its bag. Write your name, collection date and time on the card before collecting.\u003c\/li\u003e\n\u003cli\u003eOpen the cover and fold it away from the filter paper. Avoid touching the filter paper.\u003c\/li\u003e\n\u003cli\u003eFully saturate the filter paper by urinating directly onto it, or collect urine in a clean cup and dip the paper up to the top black dashed line.\u003c\/li\u003e\n\u003cli\u003eHang or tape the card somewhere secure to dry. Ensure the wet filter paper does not touch anything.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAllow the sample to dry completely for at least six hours.\u003c\/strong\u003e Once completely dry, refold the card, place it in its bag and seal it. Do not leave samples outside the bag for longer than 24 hours.\u003c\/li\u003e\n\u003cli\u003eRepeat these steps for each collection time.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eIf You Use Hormone Treatments\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eRecord all hormone treatments on your Test Requisition Form. Follow the hormone-use instructions supplied with your kit and your healthcare provider’s advice. Do not stop prescribed hormone treatment without their advice.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMorning hormones:\u003c\/strong\u003e Take or apply your usual morning dose after the first urine collection. Wash your hands thoroughly afterwards, especially after applying topical hormones.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNighttime hormones:\u003c\/strong\u003e Collect your bedtime sample before taking or applying your nighttime dose.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVaginal hormones:\u003c\/strong\u003e The laboratory’s instructions advise avoiding vaginal hormone use during the collection day until after the final urine sample. Discuss timing with your healthcare provider if needed.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eIf You Miss a Collection\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCollect the missed sample at the same time the following day. For example, collect a missed evening sample the following evening. Record the actual collection date and time on both the card and the Test Requisition Form, then follow the same drying and sealing instructions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReturning Your Samples\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eComplete the Test Requisition Form in full. Place it, any additional paperwork and all sealed, completely dry samples into the test kit box. Pack and return the kit according to the return instructions provided.\u003c\/p\u003e\n\u003cp\u003eA return envelope is provided with your kit. It is not prepaid; customers are responsible for return postage to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImportant:\u003c\/strong\u003e Urine samples that are wet, unsealed, excessively diluted or more than 30 days old will not be processed.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCollection Instructions:\u003c\/strong\u003e \u003ca class=\"text-link\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Saliva_Dried_Urine_Collection_Instructions.pdf?v=1785413203\" rel=\"nofollow\"\u003eView dried urine collection instructions\u003c\/a\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eFrequently Asked Questions\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eHow do heavy metals affect neurotransmitters?\u003c\/strong\u003e\u003cbr\u003eExposure to certain toxic elements can affect nervous-system function. This kit measures selected urinary elements alongside neurotransmitter-related markers, allowing your practitioner to review both sets of results in context. It does not establish that an exposure caused your symptoms or measure the resulting effect on brain neurotransmitters.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is iodine included in the elements panel?\u003c\/strong\u003e\u003cbr\u003eIodine is essential for thyroid hormone production. The panel measures urinary iodine alongside other selected elements, including selenium and bromine. Results should be reviewed with your healthcare practitioner and do not, by themselves, diagnose iodine deficiency or thyroid disease.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIs this test suitable for children?\u003c\/strong\u003e\u003cbr\u003eThe dried urine collection method is non-invasive and suitable for adults and children. \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan this test diagnose heavy metal poisoning or neurological conditions?\u003c\/strong\u003e\u003cbr\u003eNo. This test cannot diagnose medical conditions. It provides biochemical data about urinary excretion of neurotransmitters and elements that may help guide further investigation with a qualified healthcare professional.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee for both panels is included. Return postage to the laboratory is not included.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":40607452954710,"sku":"0099","price":439.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Neurotransmitters_Test.webp?v=1785073865"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/collections\/Dried_Urine_Spot_Test.png?v=1792433897","url":"https:\/\/hormonelab.co.uk\/de\/collections\/urine-spot-hormone-test.oembed","provider":"Hormone Lab UK","version":"1.0","type":"link"}