{"title":"Male Profile Tests","description":"\u003cp\u003eTake control of your health with our men’s hormone test kits, designed to provide clear, accurate insights into hormonal balance and overall wellbeing. These easy-to-use at-home tests measure key hormones such as testosterone, cortisol, DHEA, estrogen, and thyroid markers to help identify imbalances linked to energy, mood, performance, sleep, and weight. With simple sample collection and fast, lab-verified results, you can better understand your body and make informed decisions to optimise your health and long-term performance. All our tests are suitable for adults and children.\u003cbr\u003e\u003c\/p\u003e","products":[{"product_id":"male-adrenal-function-saliva-test-kit","title":"Male Saliva Adrenal Stress Test (LC-MS\/MS)","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e S-121 | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Saliva | \u003cstrong\u003eTechnology:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults Time:\u003c\/strong\u003e 3–5 Working Days After Laboratory Receives Sample | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eHormone Specialist Doctor Interpretation:\u003c\/strong\u003e Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit  Required\u003c\/p\u003e\n\u003ch2 data-pm-slice=\"1 1 []\"\u003e\u003cstrong\u003eWhat Does This Test Measure?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSaliva — Adrenal Profile: DHEAS plus Morning, Midday, Evening and Bedtime Cortisol.\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThis at-home profile measures \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003etwo hormones through five results\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e: one DHEAS measurement and four cortisol measurements collected throughout the day.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eDHEAS\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e is produced mainly by the adrenal glands and normally decreases with age. Your result adds information about adrenal androgen production.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eCortisol\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e participates in energy regulation, the stress response and your sleep–wake cycle. Four measurements show how your levels change across your collection day.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eYour report includes numerical results, reference ranges, graphs and specialist laboratory comments to help you understand the findings.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eRelated Symptoms\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003ePersistent tiredness or fluctuating energy\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eDifficulty becoming alert in the morning\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAfternoon energy dips\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eFeeling tired but unable to relax in the evening\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eDifficulty falling asleep, staying asleep or waking refreshed\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eFeeling stressed, tense or overwhelmed\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003e\u003cstrong\u003eWho Should Consider This Test?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eMen who want to understand their measured DHEAS level and daily cortisol pattern, particularly when tiredness, changing energy levels and sleep difficulties occur together.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe profile provides more information about cortisol across the day than a single morning measurement, with DHEAS adding a separate hormone result for interpretation.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eHow Your Results Can Help With Your Symptoms\u003c\/strong\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eMorning Tiredness or Difficulty Becoming Alert\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eRelevant result: Morning cortisol\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eYour morning measurement shows whether cortisol falls within the laboratory’s expected morning range.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePractical next steps:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Compare the result and specialist comments with your waking time, sleep duration and morning energy. Use this information to review consistent sleep and waking times, morning daylight exposure and recovery. If the report identifies a finding needing investigation—or tiredness persists—arrange a medical review.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eAfternoon Energy Dips\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eRelevant results: Midday and evening cortisol\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThese measurements show your cortisol levels later in the day and how they compare with the morning result.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePractical next steps:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Keep a brief record of energy dips, meals, caffeine and activity. Review regular meals, adequate hydration, caffeine timing and workload. The report adds hormone information to this review; it does not prescribe a particular diet.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eFeeling Tired but Unable to Relax\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eRelevant results: Evening and bedtime cortisol\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eCortisol generally decreases towards bedtime. These measurements show whether your sampled evening levels follow that pattern.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePractical next steps:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Review late caffeine, demanding evening exercise, work carried into bedtime and opportunities to wind down. Choose manageable changes and track whether settling at night becomes easier.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eDifficulty Sleeping or Waking Refreshed\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eRelevant results: Bedtime cortisol and the overall daily profile\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe bedtime result provides information that a morning measurement alone cannot offer.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePractical next steps:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Use your report alongside a sleep diary. Consider a consistent sleep schedule, morning daylight and a quieter evening routine. Persistent insomnia, loud snoring or marked daytime sleepiness warrants further assessment even if cortisol results are within range.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eFeeling Stressed or Overwhelmed\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eRelevant results: The daily cortisol profile\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eYour results show the measured cortisol pattern rather than relying on how stressed you feel alone.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePractical next steps:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Review your workload, rest, exercise intensity and relaxation habits. Use the laboratory comments to identify any findings that need follow-up, while tracking changes in stress, sleep and energy.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eWhat Does the DHEAS Result Add?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eDHEAS provides additional information that must be interpreted with age, medication and supplement use.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eA low result does not automatically mean low testosterone. In men, most testosterone is produced by the testes. If sexual symptoms are your main concern, testosterone assessment is more directly relevant.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eHow the Specialist Comments Help You\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eThe sample report demonstrates three useful features:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eResults and ranges:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Show each measured level and highlight findings outside the displayed range.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eGraphs:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Display cortisol across the day and DHEAS in an age-related context.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eLaboratory comments:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Explain how the measurements relate to age and the information supplied on your symptom form.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eComplete your symptom checklist and record medicines, supplements and collection times carefully. This helps make the interpretation more relevant to you.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eWhat Should You Do Next?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eRead the comments, note any recommended follow-up and choose practical sleep, nutrition and recovery habits to review. Track your symptoms so you can judge whether changes help.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIf results are clearly abnormal, symptoms continue or the comments suggest hormone supplements, seek medical advice before starting treatment. Laboratory interpretation helps you understand the findings; it is separate from a prescribing consultation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eSee \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/saliva-adrenal-stress.pdf?v=1786976487\" title=\"Adrenal Stress Sample Report\"\u003e\u003cstrong\u003eSaliva Adrenal Stress Sample Report\u003c\/strong\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eNot Sure Which Test Is Right for You?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca href=\"mailto:info@hormonelab.co.uk\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours.\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eHow It Works\u003c\/strong\u003e\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered directly to your door\u003c\/li\u003e\n\u003cli\u003eCollect saliva at four time points: morning (within 30 minutes of waking, before 9am), noon, evening, and night — following the detailed instructions provided\u003c\/li\u003e\n\u003cli\u003ePost your samples to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your full report by email within 3–5 working days\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003e\u003cstrong\u003eWhat You Receive\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eDHEAS result and all four cortisol readings with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eVisual chart showing your complete daily cortisol rhythm curve and DHEAS status\u003c\/li\u003e\n\u003cli\u003eWritten interpretation by a Hormone Specialist PhD Doctor including DHEAS–cortisol adrenal reserve assessment and testosterone impact analysis\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003e\u003cstrong\u003eWhy We Use ZRT Laboratory\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePioneers of at-home \u003cstrong\u003edried blood spot (DBS)\u003c\/strong\u003e and saliva hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePersonalised reference ranges based on age and sex\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThrough our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to people across the UK and Europe — from the comfort of home.\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eFrequently Asked Questions\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhat does this test measure?\u003c\/strong\u003e\u003cbr\u003eDHEAS and Cortisol at four points throughout the day (morning, noon, evening, night) — 5 markers providing a complete picture of adrenal function, DHEAS status, and their combined impact on testosterone in men.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is DHEAS important for men?\u003c\/strong\u003e\u003cbr\u003eDHEAS is the primary adrenal precursor to testosterone. Low DHEAS directly reduces testosterone availability, libido, muscle mass, and stress resilience, and is a key driver of andropause-like symptoms in men of all ages under chronic stress. It is never measured by standard NHS panels.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan I use this test if I am on TRT?\u003c\/strong\u003e\u003cbr\u003eYes. This test is particularly valuable for men on TRT wanting to understand whether adrenal dysfunction — low DHEAS or cortisol dysregulation — is undermining the effectiveness of their testosterone therapy.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy use saliva rather than blood?\u003c\/strong\u003e\u003cbr\u003eSaliva LC-MS\/MS measures free, bioavailable cortisol and DHEAS — the fractions actually active at the cellular level. A blood draw also triggers a cortisol spike that distorts results, making saliva the more clinically accurate medium for adrenal rhythm assessment.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. There are no additional charges. You are only responsible for posting your samples to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e\n\u003ch2 data-pm-slice=\"1 1 []\"\u003e\u003cstrong\u003e\u003cspan\u003eSaliva Sample Collection Instructions\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eCollect your saliva samples at home using the materials provided in your kit. \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eCheck your Test Requisition Form and kit instructions to confirm whether your test requires one, two or four samples.\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e You may not need every tube supplied.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRead all instructions before you begin. If you use hormone treatment, also read the \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eHormone Users\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e section.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003e\u003cspan\u003e1. Check Your Collection Times\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003e\u003cspan\u003eSamples required\u003c\/span\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cspan\u003eWhen to collect\u003c\/span\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eOne\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eMorning\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eTwo\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eMorning and before bed\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eFour\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eMorning, before lunch, before dinner and before bed\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cspan\u003eUse the \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003elarge 10 mL tube for your morning sample\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e and the \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003esmaller 5 mL tubes for any later samples\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e. Collect the required samples on the same day unless your kit instructions say otherwise.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003e\u003cspan\u003e2. Choose Your Collection Day\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eMark your collection day on your calendar. List all medicines, supplements and hormone treatments on your Test Requisition Form.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMen, children and women who do not menstruate:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Collect on any day of the month. If you use hormones, follow the treatment-timing instructions below.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eWomen who menstruate:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e If your test measures estradiol, progesterone or testosterone, use the following schedule:\u003c\/span\u003e\u003c\/p\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003e\u003cspan\u003eUsual menstrual-cycle length\u003c\/span\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cspan\u003eWhen to collect\u003c\/span\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003e23–26 days\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eDay 17, 18 or 19\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003e27–30 days\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eDay 21, 22 or 23\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003e31–34 days\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eDay 25, 26 or 27\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eShorter or longer regular cycles\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e5–7 days before your next expected period\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eInfrequent or unpredictable cycles\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eAny day when you are not bleeding\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eDay 1 is the first day of menstrual flow, not spotting.\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Follow any different timing instructions supplied for your particular test.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003e\u003cspan\u003e3. Hormone Users\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eSkip this section if you do not use hormones.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eRecord every hormone treatment on your Test Requisition Form.\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e This helps the laboratory choose suitable reference ranges and provide relevant comments.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eDo not stop prescribed hormone treatment for testing.\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e If collection requires changing your usual dosing time, check with your prescriber first.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003e\u003cspan\u003eTopical and Oral Hormones\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eContinue your prescribed treatment on the day before collection.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eAllow \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eat least 12 hours between an evening dose and your morning sample\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e. For example, if collecting at 8 am, take or apply the previous evening’s dose by 8 pm.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eOral progesterone is an exception:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e you may take it immediately before bed.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eFor at least \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003etwo days before collection\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, apply topical hormones using gloves or an applicator rather than bare hands.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eAvoid applying hormones to your \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eface, lips or neck\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003e\u003cspan\u003eTroches and Under-the-Tongue Hormones\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003e\u003cspan\u003eHormones that dissolve in the mouth can contaminate saliva samples. \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eSaliva hormone testing is not recommended while using these treatments.\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Ask your healthcare professional about an alternative, such as blood spot testing. Contaminated samples may be partially or fully rejected.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003e\u003cspan\u003ePatches, Vaginal Rings, Pellets and Injections\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003e\u003cspan\u003eThe laboratory advises collecting \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003ehalfway between doses or replacements\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e. For example, this may be approximately three days after applying a weekly patch or two weeks after a monthly injection.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eCheck the appropriate collection time for your particular treatment with your prescriber.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003e\u003cspan\u003eSteroid Medicines\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003e\u003cspan\u003eIf you take glucocorticoids, such as \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003ehydrocortisone or prednisone\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, ask your healthcare professional when to collect your samples.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003e\u003cspan\u003ePrevent Hormone Contamination\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003e\u003cspan\u003eTraces of hormone creams or gels can transfer from your hands, towels or household surfaces into your sample.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eChange your \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003esheets, pillowcases and towels\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e the night before collection.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAvoid touching bathroom surfaces that may contain hormone residue.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eWash your hands thoroughly and dry them with a clean towel.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003e\u003cspan\u003e4. Prepare for Collection\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eThree days before collection:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Avoid anti-ageing or anti-wrinkle facial creams and \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003ebiotin\/vitamin B7 supplements\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, including hair and nail formulas.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eThe night before collection:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Stay normally hydrated, but avoid drinking excessive amounts of fluid.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBefore your morning sample:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Do not eat, drink anything other than water, or brush your teeth.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBefore later samples:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Do not eat, drink anything other than water, or brush your teeth for at least \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003etwo hours before collection\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003e\u003cspan\u003e5. Collect Your Samples\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eWash your hands\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e with soap and water, then dry them with a clean towel.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003e\u003cspan\u003eRinse your mouth with water and wait five minutes.\u003c\/span\u003e\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eBegin your morning collection within 30 minutes of waking\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, using the large tube.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eLet saliva pool naturally in your mouth, then transfer it into the tube.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eFill the tube \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eat least halfway with liquid saliva, excluding bubbles\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e. This usually takes \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003e15–30 minutes\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, depending on saliva flow.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eScrew the cap on securely.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eLabel the tube with your \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003ename, collection date and collection time\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, then place it back in its bag.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eRepeat at each later collection time required for your test, using the smaller tubes.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eIf saliva flow is slow:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Try yawning, smelling food without eating it, or pressing the tip of your tongue against your teeth. To reduce bubbles, securely cap the tube and gently tap it on a hard surface.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003e\u003cspan\u003e6. Complete Your Paperwork and Pack Your Samples\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eComplete your Test Requisition Form, including your symptoms, medical history, medicines, supplements and hormone treatments.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eCheck that every required tube is \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eclearly labelled, securely closed and at least halfway full of liquid saliva\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003ePlace your samples, completed form and any additional paperwork inside the plastic kit box.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eInclude payment only if required under your kit’s arrangements.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eClose the box securely and place it inside the return packaging.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAttach the prepaid return label if provided, or arrange the required postage.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eReturn your samples using the carrier and return address specified in your kit instructions.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003e7. Storage and Collection Mistakes\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFreeze samples if you will not ship them within 24 hours of collection.\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Samples remain stable under average shipping conditions, including transit over weekends and holidays.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIf you need to repeat a collection, rinse the affected tube with \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003ehot water only—do not use soap\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e. Shake out the remaining water and leave the tube to air-dry before collecting again at the correct time.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIf you ate or brushed your teeth before collecting your morning sample, \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003erestart the following morning\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Saliva_Collection_Instructions.pdf?v=1786970945\"\u003e\u003cspan\u003eRead the full Saliva Collection Instructions\u003c\/span\u003e\u003c\/a\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":32918206793,"sku":"100","price":189.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Saliva_Hormone_Panel_Test.png?v=1785073869"},{"product_id":"male-cardiometabolic-test-kit","title":"Male CardioMetabolic Test Kit | Insulin, HbA1c, Cholesterol \u0026 CRP","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e B-222M | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Dried Blood Spot | \u003cstrong\u003eTest Method:\u003c\/strong\u003e Immunoassay | \u003cstrong\u003eResults:\u003c\/strong\u003e 3–5 Working Days | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eReport:\u003c\/strong\u003e Specialist Doctor Comment Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Men | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required | \u003cstrong\u003eImportant:\u003c\/strong\u003e Must Be Collected Fasting\u003c\/p\u003e\n\u003ch2\u003eWhat This Test Measures\u003c\/h2\u003e\n\u003cp\u003eSix clinically validated markers to assess cardiovascular risk, diabetes progression, and systemic inflammation:\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFasting Insulin (IN)\u003c\/strong\u003e — the earliest and most sensitive marker of insulin resistance, detectable before blood sugar rises\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHbA1c (Haemoglobin A1c)\u003c\/strong\u003e — your 3-month average blood sugar level; used to screen for pre-diabetes and type 2 diabetes\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHigh-Sensitivity CRP (hs-CRP)\u003c\/strong\u003e — a key marker of systemic inflammation linked to cardiovascular disease, atherosclerosis, and metabolic dysfunction\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTriglycerides (TG)\u003c\/strong\u003e — blood fats that rise with poor diet, insulin resistance, and excess alcohol; a strong independent predictor of cardiovascular disease\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTotal Cholesterol (CH)\u003c\/strong\u003e — overall cholesterol status; a core cardiovascular screening marker\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHDL Cholesterol (HDL)\u003c\/strong\u003e — the protective “good” cholesterol; low HDL is a strong predictor of heart disease risk\u003c\/p\u003e\n\u003cp\u003eTogether these markers provide a clinically relevant evaluation of your risk for atherosclerotic cardiovascular disease, type 2 diabetes, metabolic syndrome, and chronic inflammation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCardiometabolic Test Reference Ranges\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eTest\u003c\/th\u003e\n\u003cth align=\"right\"\u003eUnit\u003c\/th\u003e\n\u003cth align=\"right\"\u003eWomen\u003c\/th\u003e\n\u003cth align=\"right\"\u003eMen\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eTotal Cholesterol (CH)\u003c\/td\u003e\n\u003ctd align=\"right\"\u003emg\/dL\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e132–239\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e132–239\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHDL Cholesterol (HDL)\u003c\/td\u003e\n\u003ctd align=\"right\"\u003emg\/dL\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e40–60\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e40–60\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLDL Cholesterol (LDL)\u003c\/td\u003e\n\u003ctd align=\"right\"\u003emg\/dL\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e\u0026lt;160\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e\u0026lt;160\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLDL Cholesterol—Optimum\u003c\/td\u003e\n\u003ctd align=\"right\"\u003emg\/dL\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e100–159\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e100–159\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVLDL Cholesterol (VLDL)\u003c\/td\u003e\n\u003ctd align=\"right\"\u003emg\/dL\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e\u0026lt;30\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e\u0026lt;30\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTriglycerides (TG)\u003c\/td\u003e\n\u003ctd align=\"right\"\u003emg\/dL\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e\u0026lt;150\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e\u0026lt;150\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHaemoglobin A1c (HbA1c)\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e%\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e4–6\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e4–6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFasting Insulin (Ins)\u003c\/td\u003e\n\u003ctd align=\"right\"\u003eμIU\/mL\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e1–15\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e1–15\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFasting Insulin—Optimum\u003c\/td\u003e\n\u003ctd align=\"right\"\u003eμIU\/mL\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e2–6\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e2–6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHigh-Sensitivity C-Reactive Protein (hs-CRP)\u003c\/td\u003e\n\u003ctd align=\"right\"\u003emg\/L\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e\u0026lt;3\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e\u0026lt;3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003eAre You at Risk of Heart Disease, Diabetes, or Metabolic Syndrome Without Knowing It?\u003c\/h2\u003e\n\u003cp\u003eCardiovascular disease is the leading cause of death in men in the UK — yet most men have never had a comprehensive assessment of their metabolic and cardiac risk. The warning signs often develop silently over years, dismissed as stress, weight gain, or simply getting older. Insulin resistance, elevated triglycerides, and chronic low-grade inflammation can all be well established long before a heart attack or diabetes diagnosis. This comprehensive 6-marker panel is designed to catch the warning signs early. If you recognise any of the following, this test could be one of the most important health checks you take:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHigh blood pressure or a family history of heart disease or type 2 diabetes\u003c\/li\u003e\n\u003cli\u003eWeight gain around the abdomen or difficulty losing belly fat\u003c\/li\u003e\n\u003cli\u003eElevated triglycerides or high cholesterol on previous tests\u003c\/li\u003e\n\u003cli\u003eFatigue, brain fog, or persistent sugar cravings\u003c\/li\u003e\n\u003cli\u003eReduced erections or low libido — an early sign of cardiovascular and metabolic dysfunction\u003c\/li\u003e\n\u003cli\u003eMuscle loss, soreness, or reduced exercise performance\u003c\/li\u003e\n\u003cli\u003eEnergy crashes after meals or difficulty maintaining a healthy weight\u003c\/li\u003e\n\u003cli\u003eNumbness or tingling in feet or hands\u003c\/li\u003e\n\u003cli\u003eAlready diagnosed with metabolic syndrome, pre-diabetes, or cardiovascular disease\u003c\/li\u003e\n\u003cli\u003eCurrently taking cholesterol-lowering medication or TRT\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy Cardiometabolic Health Is a Critical Priority for Men\u003c\/h2\u003e\n\u003cp\u003eMen develop cardiovascular disease on average 7–10 years earlier than women, and are more likely to have a heart attack without prior warning. Testosterone plays a complex role in metabolic health — low testosterone is independently associated with insulin resistance, elevated triglycerides, and increased visceral fat, creating a feedback loop that accelerates cardiometabolic decline. Men on TRT, those with suspected andropause, or anyone carrying excess abdominal weight should consider this panel an essential baseline.\u003c\/p\u003e\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eMen with no recent comprehensive cardiovascular or metabolic check\u003c\/li\u003e\n\u003cli\u003eFamily history of heart disease, stroke, or type 2 diabetes\u003c\/li\u003e\n\u003cli\u003eAbdominal weight gain, poor diet, or limited exercise\u003c\/li\u003e\n\u003cli\u003eFatigue, brain fog, sugar cravings, or energy crashes after meals\u003c\/li\u003e\n\u003cli\u003eLow libido or erectile dysfunction — early cardiovascular warning signs\u003c\/li\u003e\n\u003cli\u003eCurrently on TRT — monitoring cardiometabolic impact is clinically recommended\u003c\/li\u003e\n\u003cli\u003eAlready diagnosed with metabolic syndrome, pre-diabetes, or cardiovascular disease\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered to your door\u003c\/li\u003e\n\u003cli\u003eCollect your sample at home — a simple finger-prick dried blood spot taken while fasting (no food or drink other than water); no clinic or GP visit needed\u003c\/li\u003e\n\u003cli\u003ePost your sample to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your results by email within 3–5 working days of the lab receiving your sample\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll six markers displayed clearly in graphics and numbers with reference and optimal ranges\u003c\/li\u003e\n\u003cli\u003eWritten interpretation by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003eGuidance on what your results mean and what to do next\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDo I need to fast before collecting my sample?\u003c\/strong\u003e\u003cbr\u003eYes — fasting is essential for this panel. Collect your sample within 1 hour of waking, having had nothing to eat or drink except water since the previous evening. Fasting ensures accurate insulin and triglyceride results, which are significantly affected by recent food intake.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow does low testosterone relate to cardiometabolic risk?\u003c\/strong\u003e\u003cbr\u003eLow testosterone is independently associated with insulin resistance, elevated triglycerides, increased visceral fat, and reduced HDL — all of which are components of metabolic syndrome. Men with andropause symptoms or on TRT benefit particularly from regular cardiometabolic monitoring.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is hs-CRP and why does it matter?\u003c\/strong\u003e\u003cbr\u003eHigh-sensitivity CRP is a marker of systemic low-grade inflammation — a key driver of atherosclerosis and cardiovascular events. Elevated hs-CRP is associated with a 2–3x increased risk of heart attack and stroke, even in men with apparently normal cholesterol.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. You are only responsible for posting your sample to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":43583034889,"sku":"550","price":192.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Insulin_Test_Kit.png?v=1787500073"},{"product_id":"male-toxic-essential-elements-test","title":"Male Toxic \u0026 Essential Elements Test","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e B-224M | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Dried Blood Spot | \u003cstrong\u003eTest Method:\u003c\/strong\u003e ICP-MS | \u003cstrong\u003eResults:\u003c\/strong\u003e 3–5 Working Days | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eReport:\u003c\/strong\u003e Specialist Doctor Comment Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Men | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\u003ch2\u003eWhat This Test Measures\u003c\/h2\u003e\n\u003cp\u003eSix toxic and essential elements via ICP-MS from a simple finger-prick dried blood spot:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCadmium (Cd)\u003c\/strong\u003e — toxic metal accumulating in the kidneys; strongly linked to reduced testosterone, impaired sperm production, and prostate health risks; sources include cigarette smoke, contaminated food, and occupational exposure\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMercury (Hg)\u003c\/strong\u003e — organic mercury from fish and dental amalgam binds to red blood cells; associated with thyroid damage, neurological decline, and testosterone disruption\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSelenium (Se)\u003c\/strong\u003e — essential for thyroid hormone conversion, antioxidant defence, and sperm motility; deficiency is common in the UK and linked to reduced fertility and cardiovascular risk in men\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eZinc (Zn)\u003c\/strong\u003e — essential for testosterone production, sperm quality, immune function, and wound healing; one of the most common nutritional causes of low testosterone in men\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMagnesium (Mg)\u003c\/strong\u003e — involved in 300+ enzymatic reactions including testosterone synthesis, muscle function, and cardiovascular health; deficiency linked to low energy, poor sleep, and muscle cramps\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCopper (Cu)\u003c\/strong\u003e — essential in balance with zinc; excess copper suppresses testosterone and impairs immunity; the zinc-to-copper ratio is a key health marker for men\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eCould Heavy Metals or Mineral Imbalances Be Affecting Your Energy, Performance, or Hormones?\u003c\/h2\u003e\n\u003cp\u003eToxic elements like mercury and cadmium accumulate silently in the body over years, while deficiencies in essential minerals like selenium, zinc, and magnesium can directly impair testosterone production, energy metabolism, cardiovascular health, and cognitive function in men. Symptoms are often misattributed to stress, ageing, or low testosterone — when the underlying driver is elemental imbalance. If you recognise any of the following, this test could uncover a hidden root cause:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePersistent fatigue or low energy that rest does not resolve\u003c\/li\u003e\n\u003cli\u003eBrain fog, slow thinking, or poor concentration\u003c\/li\u003e\n\u003cli\u003eMuscle weakness, cramps, or reduced exercise performance\u003c\/li\u003e\n\u003cli\u003eAnxiety, irritability, low mood, or reduced motivation\u003c\/li\u003e\n\u003cli\u003eDifficulty sleeping or restlessness\u003c\/li\u003e\n\u003cli\u003eTingling, numbness, or twitching in hands and fingers\u003c\/li\u003e\n\u003cli\u003eIrregular heartbeat or palpitations\u003c\/li\u003e\n\u003cli\u003eBrittle hair and nails, dry or scaly skin\u003c\/li\u003e\n\u003cli\u003eReduced libido or sexual performance issues\u003c\/li\u003e\n\u003cli\u003eElevated cholesterol or high blood pressure\u003c\/li\u003e\n\u003cli\u003eConcerns about heavy metal exposure from diet, fish, environment, or dental fillings\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy These Elements Matter Specifically for Men\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eTestosterone suppression and hormonal disruption via heavy metal endocrine interference\u003c\/li\u003e\n\u003cli\u003eReduced sperm quality and male fertility problems\u003c\/li\u003e\n\u003cli\u003eThyroid dysfunction — mercury and cadmium interfere with thyroid hormone production\u003c\/li\u003e\n\u003cli\u003eNeurological decline and cognitive impairment\u003c\/li\u003e\n\u003cli\u003eCardiovascular disease and hypertension\u003c\/li\u003e\n\u003cli\u003eImmune suppression and increased chronic disease risk\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eUnexplained fatigue, low libido, or reduced physical performance\u003c\/li\u003e\n\u003cli\u003eRegular consumption of fish, especially tuna, swordfish, or shark\u003c\/li\u003e\n\u003cli\u003eConcerns about occupational or environmental heavy metal exposure\u003c\/li\u003e\n\u003cli\u003eInvestigating selenium and zinc as part of a testosterone, thyroid, or fertility workup\u003c\/li\u003e\n\u003cli\u003eMonitoring mineral status during supplementation or TRT\u003c\/li\u003e\n\u003cli\u003eProactive assessment of long-term hormonal and cardiovascular health\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered to your door\u003c\/li\u003e\n\u003cli\u003eCollect your sample at home — a simple finger-prick dried blood spot; no clinic or GP visit needed\u003c\/li\u003e\n\u003cli\u003ePost your sample to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your results by email within 3–5 working days of the lab receiving your sample\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll 6 element levels displayed clearly in graphics and numbers with sex-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eWritten interpretation by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003eGuidance on what your results mean and recommended next steps\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e. ZRT’s advanced \u003cstrong\u003eICP-MS\u003c\/strong\u003e technology delivers clinical-grade trace element accuracy from a home-collected dried blood spot.\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eCan heavy metals really lower testosterone?\u003c\/strong\u003e\u003cbr\u003eYes. Cadmium and mercury are both endocrine disruptors shown in clinical research to suppress testosterone production, interfere with the hypothalamic-pituitary-gonadal axis, and impair Leydig cell function in the testes.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes zinc deficiency cause low testosterone?\u003c\/strong\u003e\u003cbr\u003eYes. Zinc is a cofactor in testosterone biosynthesis and is required for the function of luteinising hormone (LH). Zinc deficiency is one of the most consistently identified nutritional causes of low testosterone in men.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow does the copper-to-zinc ratio affect men’s health?\u003c\/strong\u003e\u003cbr\u003eCopper and zinc compete for absorption. Elevated copper relative to zinc can suppress testosterone, impair immune function, increase anxiety, and drive oestrogen dominance in men. The ratio is more informative than either value alone.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. You are only responsible for posting your sample to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":2170568441865,"sku":"545","price":148.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Insulin_Test_Kit.png?v=1787500073"},{"product_id":"male-thyroid-test-kit","title":"Male Thyroid Test Kit | TSH, Free T3, T4 \u0026 TPOab","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e B-220M | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Dried Blood Spot | \u003cstrong\u003eTest Method:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults:\u003c\/strong\u003e 3–5 Working Days | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eReport:\u003c\/strong\u003e Specialist Doctor Comment Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Men | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\u003ch2\u003eWhy a Full Thyroid Panel Matters for Men\u003c\/h2\u003e\n\u003cp\u003eA standard GP thyroid test typically only measures TSH — which can miss significant thyroid dysfunction. In men, thyroid imbalance can closely mimic symptoms of low testosterone, making it frequently overlooked or misattributed. This comprehensive panel measures \u003cstrong\u003esix thyroid markers\u003c\/strong\u003e, giving a complete picture of thyroid hormone production, conversion, autoimmune activity, and iodine-related health:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTSH (Thyroid Stimulating Hormone)\u003c\/strong\u003e — the primary screening marker; high TSH suggests hypothyroidism, low TSH suggests hyperthyroidism\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFree T4 (fT4)\u003c\/strong\u003e — the main hormone produced by the thyroid; assesses production capacity\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFree T3 (fT3)\u003c\/strong\u003e — the active thyroid hormone that drives energy, metabolism, and cellular function; some men have normal T4 but poor T4-to-T3 conversion, causing persistent symptoms despite apparently normal results\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTotal T4 (TT4)\u003c\/strong\u003e — measures both bound and free thyroxine; provides a broader view of thyroid output\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTPO Antibodies (TPOab)\u003c\/strong\u003e — elevated levels indicate autoimmune thyroid disease such as Hashimoto’s thyroiditis\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThyroglobulin (Tgbn)\u003c\/strong\u003e — linked to iodine storage and thyroid hormone production; elevated levels may suggest iodine deficiency or thyroid dysfunction\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eThyroid Test Reference Ranges\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"rte__table-wrapper\"\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eTest\u003c\/th\u003e\n\u003cth align=\"right\"\u003eUnit\u003c\/th\u003e\n\u003cth align=\"right\"\u003eWomen\u003c\/th\u003e\n\u003cth align=\"right\"\u003eMen\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eFree Thyroxine (fT4)\u003c\/td\u003e\n\u003ctd align=\"right\"\u003eng\/dL\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e0.8–1.6\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e0.8–1.6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFree Triiodothyronine (fT3)\u003c\/td\u003e\n\u003ctd align=\"right\"\u003epg\/mL\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e1.9–4.4\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e1.9–4.4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eThyroglobulin (Tgbn)\u003c\/td\u003e\n\u003ctd align=\"right\"\u003eng\/mL\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e5–51\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e4–34\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eThyroid Peroxidase Antibodies (TPOab)\u003c\/td\u003e\n\u003ctd align=\"right\"\u003eIU\/mL\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e0–150\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e0–150\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTPOab—Borderline\u003c\/td\u003e\n\u003ctd align=\"right\"\u003eIU\/mL\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e70–150\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e70–150\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eThyroid-Stimulating Hormone (TSH)\u003c\/td\u003e\n\u003ctd align=\"right\"\u003eμU\/mL\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e0.5–3.0\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e0.5–3.0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTotal Thyroxine (T4)\u003c\/td\u003e\n\u003ctd align=\"right\"\u003eμg\/dL\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e5–10.6\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e5–10.6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003ch2\u003eCould Your Thyroid Be Affecting Your Energy, Weight, or Performance?\u003c\/h2\u003e\n\u003cp\u003eThyroid dysfunction in men is widely underdiagnosed — not because it is rare, but because symptoms are often attributed to overwork, low testosterone, or simply ageing. The thyroid regulates your metabolism, body composition, cardiovascular health, and sexual function. If you recognise any of the following, a comprehensive thyroid test could reveal what is actually going on:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePersistent fatigue or low energy that rest does not resolve\u003c\/li\u003e\n\u003cli\u003eUnexplained weight gain, difficulty losing body fat, or slowed metabolism\u003c\/li\u003e\n\u003cli\u003eReduced exercise tolerance or muscle weakness\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor focus, or slowed thinking\u003c\/li\u003e\n\u003cli\u003eLow mood, depression, or reduced motivation\u003c\/li\u003e\n\u003cli\u003eHair thinning or loss, including body hair\u003c\/li\u003e\n\u003cli\u003eFeeling cold all the time, or conversely, intolerance to heat\u003c\/li\u003e\n\u003cli\u003eConstipation or digestive sluggishness\u003c\/li\u003e\n\u003cli\u003eReduced libido or sexual performance issues\u003c\/li\u003e\n\u003cli\u003eElevated cholesterol or high blood pressure\u003c\/li\u003e\n\u003cli\u003eAlready on thyroid medication and wanting to monitor treatment\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"rte__table-wrapper\"\u003e\u003c\/div\u003e\n\u003ch2\u003eWhat Conditions Can This Test Help Identify?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypothyroidism\u003c\/strong\u003e — underactive thyroid; commonly confused with low testosterone or burnout in men\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHyperthyroidism\u003c\/strong\u003e — overactive thyroid, including Graves’ disease\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHashimoto’s thyroiditis\u003c\/strong\u003e — autoimmune thyroid disease; often missed without TPO antibody testing\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSubclinical thyroid dysfunction\u003c\/strong\u003e — abnormal TSH with normal T4\/T3; can cause significant symptoms while going undetected on standard tests\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eT4-to-T3 conversion issues\u003c\/strong\u003e — normal T4 but insufficient active T3; a common cause of persistent fatigue and low performance in men\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIodine-related thyroid dysfunction\u003c\/strong\u003e — assessed via thyroglobulin\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered to your door\u003c\/li\u003e\n\u003cli\u003eCollect your sample at home — a simple finger-prick dried blood spot; no clinic or GP visit needed\u003c\/li\u003e\n\u003cli\u003ePost your sample to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your results by email within 3–5 working days of the lab receiving your sample\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll six thyroid markers displayed clearly in graphics and numbers with sex-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eWritten interpretation by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003eGuidance on what your results mean and what to do next\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is TSH alone not enough?\u003c\/strong\u003e\u003cbr\u003eTSH reflects the pituitary’s signal to the thyroid but does not show whether the thyroid is producing adequate T4, whether T4 is converting to active T3, or whether an autoimmune process is attacking thyroid tissue. Many men with persistently low energy, mood issues, or weight gain have normal TSH but significant dysfunction in these downstream markers.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow is thyroid dysfunction different from low testosterone in men?\u003c\/strong\u003e\u003cbr\u003eThe symptoms overlap significantly — fatigue, low libido, reduced muscle mass, brain fog, and low mood can result from either or both. Testing both thyroid and testosterone panels gives a clear picture of which hormonal system is contributing to your symptoms.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. You are only responsible for posting your sample to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":39773285351510,"sku":"5001","price":149.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Insulin_Test_Kit.png?v=1787500073"},{"product_id":"male-lipid-test-kit","title":"Male Lipid Test Kit | Cholesterol, HDL \u0026 Triglycerides","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e B-221M | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Dried Blood Spot | \u003cstrong\u003eTest Method:\u003c\/strong\u003e Immunoassay | \u003cstrong\u003eResults:\u003c\/strong\u003e 3–5 Working Days | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eReport:\u003c\/strong\u003e Specialist Doctor Comment Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Men | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\u003ch2\u003eWhat This Test Measures\u003c\/h2\u003e\n\u003cp\u003eThree essential cardiovascular and metabolic markers from a simple finger-prick dried blood spot:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTotal Cholesterol (CH)\u003c\/strong\u003e — your overall cholesterol level; a key indicator of cardiovascular health; men with low testosterone or high abdominal fat often show elevated total cholesterol even on a reasonable diet\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHDL Cholesterol (HDL)\u003c\/strong\u003e — the protective “good” cholesterol that transports cholesterol away from arteries; low HDL is particularly common in men with insulin resistance, high triglycerides, or excess belly fat and is a strong independent predictor of heart attack risk\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTriglycerides (TG)\u003c\/strong\u003e — blood fats that rise with poor diet, excess alcohol, insulin resistance, and low testosterone; high triglycerides are a major cardiovascular risk factor and a core feature of metabolic syndrome\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eTogether these markers give a clear picture of your heart health, fat metabolism, and metabolic risk.\u003c\/p\u003e\n\u003ch2\u003eCould Your Cholesterol or Triglycerides Be Putting Your Heart at Risk?\u003c\/h2\u003e\n\u003cp\u003eMen develop cardiovascular disease on average 7–10 years earlier than women — yet most have never had a proper assessment of their lipid profile. High cholesterol and elevated triglycerides typically cause \u003cstrong\u003eno obvious symptoms\u003c\/strong\u003e until significant arterial damage has already occurred. Poor diet, excess alcohol, low testosterone, insulin resistance, and abdominal fat all drive unfavourable lipid patterns in men. If you recognise any of the following, a lipid test could give you the clarity you need:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFatigue or low energy with no clear cause\u003c\/li\u003e\n\u003cli\u003eWeight gain, especially around the abdomen\u003c\/li\u003e\n\u003cli\u003eBrain fog or difficulty concentrating\u003c\/li\u003e\n\u003cli\u003eFamily history of heart disease, stroke, or high cholesterol\u003c\/li\u003e\n\u003cli\u003eHigh-sugar, high-fat diet, or regular alcohol consumption\u003c\/li\u003e\n\u003cli\u003eReduced libido or erectile dysfunction (an early sign of cardiovascular dysfunction)\u003c\/li\u003e\n\u003cli\u003eDiagnosed with metabolic syndrome, insulin resistance, or type 2 diabetes\u003c\/li\u003e\n\u003cli\u003eCurrently on TRT or concerned about the cardiovascular impact of testosterone therapy\u003c\/li\u003e\n\u003cli\u003eNo recent cardiovascular blood test\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eLipid Test Reference Ranges\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eTest\u003c\/th\u003e\n\u003cth align=\"right\"\u003eUnit\u003c\/th\u003e\n\u003cth align=\"right\"\u003eWomen\u003c\/th\u003e\n\u003cth align=\"right\"\u003eMen\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eTotal Cholesterol (CH)\u003c\/td\u003e\n\u003ctd align=\"right\"\u003emg\/dL\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e132–239\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e132–239\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHDL Cholesterol (HDL)\u003c\/td\u003e\n\u003ctd align=\"right\"\u003emg\/dL\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e40–60\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e40–60\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTriglycerides (TG)\u003c\/td\u003e\n\u003ctd align=\"right\"\u003emg\/dL\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e\u0026lt;150\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e\u0026lt;150\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003e\u003cbr\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhat Do These Lipid Markers Mean?\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eTest\u003c\/th\u003e\n\u003cth\u003eSimple explanation\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eTotal Cholesterol (CH)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eMeasures the overall amount of cholesterol in your blood, including HDL, LDL and other cholesterol-carrying particles. Your result should be interpreted alongside HDL, LDL, triglycerides and personal cardiovascular risk factors. The laboratory reference interval is \u003cstrong\u003e132–239 mg\/dL\u003c\/strong\u003e, but being within this interval does not necessarily mean the result is ideal.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eHDL Cholesterol (HDL)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eOften called “good cholesterol.” HDL helps transport cholesterol away from the arteries and back to the liver for removal. Higher HDL is generally considered more favourable. The stated laboratory range is \u003cstrong\u003e40–60 mg\/dL\u003c\/strong\u003e. Healthy targets can differ by sex; HDL above 40 mg\/dL for men and above 50 mg\/dL for women is generally considered favourable. \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eTriglycerides (TG)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eA type of fat used by the body to store energy. Elevated levels may be associated with increased cardiovascular risk, particularly when combined with high LDL or low HDL. A fasting triglyceride result below \u003cstrong\u003e150 mg\/dL\u003c\/strong\u003e is generally considered healthy. \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eThese results should not be considered individually. A healthcare professional may also consider LDL, non-HDL cholesterol, blood pressure, diabetes, smoking, age and family history when assessing cardiovascular risk. \u003c\/p\u003e\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eMen with no recent cholesterol or lipid check\u003c\/li\u003e\n\u003cli\u003eFamily history of heart disease, stroke, or high cholesterol\u003c\/li\u003e\n\u003cli\u003eAbdominal weight gain, poor diet, or regular alcohol use\u003c\/li\u003e\n\u003cli\u003eDiagnosed with or suspected metabolic syndrome or insulin resistance\u003c\/li\u003e\n\u003cli\u003eCurrently on TRT — monitoring lipid impact is clinically recommended\u003c\/li\u003e\n\u003cli\u003eReduced libido or erectile dysfunction as potential early cardiovascular signals\u003c\/li\u003e\n\u003cli\u003eAnyone wanting a proactive approach to heart health and longevity\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered to your door\u003c\/li\u003e\n\u003cli\u003eCollect your sample at home — a simple finger-prick dried blood spot; no clinic or GP visit needed; fasting for 8–12 hours before collection is recommended for most accurate triglyceride results\u003c\/li\u003e\n\u003cli\u003ePost your sample to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your results by email within 3–5 working days of the lab receiving your sample\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eTotal Cholesterol, HDL, and Triglycerides displayed clearly in graphics and numbers\u003c\/li\u003e\n\u003cli\u003eWritten interpretation by a Specialist PhD Doctor including cardiovascular and metabolic risk assessment\u003c\/li\u003e\n\u003cli\u003eGuidance on what your results mean and what to do next\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDo I need to fast before collecting my sample?\u003c\/strong\u003e\u003cbr\u003eFasting for 8–12 hours before collection is recommended for the most accurate triglyceride result. Cholesterol and HDL are less affected by fasting but consistency improves comparability if you are monitoring over time.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy does TRT affect lipid levels?\u003c\/strong\u003e\u003cbr\u003eTestosterone therapy can influence HDL, total cholesterol, and triglycerides. Regular lipid monitoring is recommended for all men on TRT to ensure the cardiovascular impact remains within a healthy range.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. You are only responsible for posting your sample to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":57737688220029,"sku":"20261","price":131.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Insulin_Test_Kit.png?v=1787500073"},{"product_id":"male-morning-cortisol-saliva-test","title":"Male Morning Cortisol Saliva Test","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e S-101 | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Saliva | \u003cstrong\u003eTechnology:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults Time:\u003c\/strong\u003e 3–5 Working Days After Laboratory Receives Sample | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eHormone Specialist Doctor Interpretation:\u003c\/strong\u003e Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\u003ch2\u003eWhat Does This Test Measure?\u003c\/h2\u003e\n\u003cp data-pm-slice=\"1 1 []\"\u003e\u003cstrong\u003eSaliva — Morning Cortisol (LC-MS\/MS): \u003c\/strong\u003e\u003cspan\u003eA single morning saliva sample measures \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003efree cortisol at the time of collection\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, providing a convenient starting point for reviewing morning tiredness and stress-related concerns. Collect your sample according to the timing instructions supplied with your kit. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-pm-slice=\"1 1 []\"\u003e\u003cspan\u003e\u003cmeta charset=\"utf-8\"\u003e1 marker — the most accessible entry-point cortisol assessment for men with primarily morning symptoms.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eRelated Symptoms\u003c\/span\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eWaking unrefreshed\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003ePersistent morning tiredness or difficulty becoming alert\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eLow morning energy\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eFeeling stressed, tense or overwhelmed\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eFeeling tired but unable to relax\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003e\u003cspan\u003eHow Your Results Can Help\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eYour result shows how your morning cortisol measurement compares with the laboratory’s reference range. Reviewed alongside your symptoms, sleep schedule, medicines and daily routine, it can guide a discussion about sleep habits, caffeine intake, exercise and recovery.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eYour healthcare professional can also use the result to decide whether a fuller daily cortisol profile, cortisol awakening response test or other investigations would be useful.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003eDid You Know?\u003c\/h2\u003e\n\u003cp\u003eCortisol and testosterone share the same hormonal precursor — pregnenolone. Under chronic stress, the body prioritises cortisol production at the direct expense of testosterone synthesis, a process known as pregnenolone steal. Chronically elevated morning cortisol also promotes abdominal visceral fat, which increases aromatase activity and converts testosterone to estradiol, compounding androgenic decline. A blunted morning cortisol, by contrast, signals adrenal insufficiency associated with burnout, chronic exhaustion, and impaired stress resilience.\u003c\/p\u003e\n\u003ch2 data-pm-slice=\"1 1 []\"\u003e\u003cspan\u003eWho Should Consider This Test?\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eThis single-sample test is for men who want a morning cortisol measurement to review with their healthcare professional, particularly when experiencing:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003ePersistent morning tiredness or low energy\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eDifficulty becoming alert after waking\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eWaking unrefreshed\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eFeeling stressed, tense or overwhelmed\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eIt offers convenient at-home collection and a snapshot of your morning cortisol level. Your result can support a review of your symptoms, sleep and daily routine, and help your practitioner decide whether a fuller cortisol profile or other investigations would be useful. Also see:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/hormonelab.co.uk\/collections\/saliva-hormone-tests\/products\/male-all-day-cortisol-test-lcms\" title=\"Male All Day Cortisol Test\"\u003e\u003cstrong\u003eMale All Day Cortisol Test\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/hormonelab.co.uk\/collections\/saliva-hormone-tests\/products\/male-cortisol-awakening-response-car-test\" title=\"Male Cortisol Awakening Response Test\"\u003e\u003cstrong\u003eMale Cortisol Awakening Response (Car) Test\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Single_Tube_Saliva_Collection_Instructions.pdf?v=1786970944\" title=\"Saliva Sample Collection Instruction\"\u003e\u003cstrong\u003eSaliva Sample Collection Instruction\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003ch2 data-pm-slice=\"1 1 []\"\u003e\u003cspan\u003eWhy Consider Morning Cortisol Testing?\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eCortisol participates in your body’s stress response, energy regulation and sleep–wake cycle. A morning measurement provides additional information when reviewing persistent morning tiredness, difficulty becoming alert or feeling stressed and overwhelmed.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMeasure free cortisol\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eSaliva testing measures the unbound fraction of cortisol at the time of collection, providing a morning result to review alongside your symptoms and health history.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCollect conveniently at home\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eA single saliva sample offers a simple collection method without a blood draw or clinic visit.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGuide your next steps\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eYour healthcare professional can use the result alongside your sleep schedule, medicines and daily routine to decide whether further investigations, a daily cortisol profile or a cortisol awakening response test would be useful.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eFor men experiencing several overlapping concerns, the result can contribute to a broader assessment that includes testosterone or other hormone tests where appropriate.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca href=\"mailto:info@hormonelab.co.uk\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours.\u003c\/p\u003e\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered directly to your door\u003c\/li\u003e\n\u003cli\u003eCollect your saliva sample within 30 minutes of waking (before 9am, ideally 6–8am), before eating, drinking, or brushing your teeth\u003c\/li\u003e\n\u003cli\u003ePost your sample to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your full report by email within 3–5 working days\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eMorning cortisol result with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eVisual chart showing your result in clinical context\u003c\/li\u003e\n\u003cli\u003eWritten interpretation by a Hormone Specialist PhD Doctor including cortisol–testosterone interaction assessment\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePioneers of at-home \u003cstrong\u003edried blood spot (DBS)\u003c\/strong\u003e and saliva hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePersonalised reference ranges based on age and sex\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThrough our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to people across the UK and Europe — from the comfort of home.\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is morning cortisol important for men?\u003c\/strong\u003e\u003cbr\u003eCortisol and testosterone share the pregnenolone precursor. Chronically high morning cortisol suppresses testosterone through pregnenolone steal, impairs sleep-based testosterone synthesis, and promotes visceral fat that drives estradiol conversion. It is one of the most common hidden drivers of low testosterone symptoms in men.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDo I need to fast before collecting?\u003c\/strong\u003e\u003cbr\u003eNo fasting is required. Collect your sample within 30 minutes of waking, before eating, drinking, or brushing your teeth.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan I use this test if I am on TRT?\u003c\/strong\u003e\u003cbr\u003eYes. This test helps men on TRT understand how cortisol is interacting with their testosterone therapy and adrenal function.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eShould I upgrade to the 4-point cortisol test instead?\u003c\/strong\u003e\u003cbr\u003eIf you suspect cortisol is elevated or disrupted throughout the day — particularly with evening anxiety, night waking, or afternoon energy crashes — the Male All Day Cortisol Test (SAL-CORT-4PT) provides the complete daily cortisol rhythm. The morning test is the most appropriate starting point for men with primarily morning symptoms or as a first-step assessment.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. There are no additional charges. You are only responsible for posting your sample to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e\n\u003ch2 data-pm-slice=\"1 1 []\"\u003e\u003cstrong\u003eHow to Collect Your Saliva Sample\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eCollect \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eone morning saliva sample at home\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e using the tube supplied with your kit. No blood draw or clinic visit is required.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eChoose Your Collection Day\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eFor women testing estradiol, progesterone or testosterone, collection timing depends on your menstrual cycle:\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"rte__table-wrapper\"\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003e\u003cspan\u003eYour usual cycle length\u003c\/span\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cspan\u003eCollection day\u003c\/span\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003e23–26 days\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eDay 17, 18 or 19\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003e27–30 days\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eDay 21, 22 or 23\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003e31–34 days\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eDay 25, 26 or 27\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eShorter or longer regular cycles\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e5–7 days before your next expected period\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eInfrequent or unpredictable cycles\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eAny non-bleeding day\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eNo menstrual periods\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eAny day, following treatment-timing instructions where applicable\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eDay 1 is the first day of menstrual flow, not spotting.\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003ePrepare for Collection\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eThree days before:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Avoid anti-ageing or anti-wrinkle facial creams and biotin\/vitamin B7 supplements, including hair and nail formulas.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eThe night before:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Stay normally hydrated without drinking excessive amounts.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eOn collection morning:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Do not eat, drink anything except water, or brush your teeth before collecting.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eRecord all medicines, supplements and hormone treatments on your Test Requisition Form.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eCollect Your Sample\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eWash and dry your hands, rinse your mouth with water and wait \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003efive minutes\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003e\u003cspan\u003eBegin collection within 30 minutes of waking.\u003c\/span\u003e\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAllow saliva to collect naturally in your mouth, then transfer it into the tube.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eFill the tube \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eat least halfway, excluding bubbles\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e. Collection usually takes 15–30 minutes.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eSecure the cap and label the tube with your name, collection date and time.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eIf You Use Hormone Treatment\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eContinue prescribed treatment and follow the treatment-specific timing instructions in the leaflet. For topical hormones, use gloves or an applicator for at least two days before collection to help prevent contamination. If you use steroids, troches or under-the-tongue hormone treatments, discuss collection suitability and timing with your healthcare professional.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eReturn Your Sample\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003ePlace the labelled tube and completed paperwork in the supplied kit packaging and follow the return-postage instructions. \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eFreeze the sample if it will not be shipped within 24 hours.\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Single_Tube_Saliva_Collection_Instructions.pdf?v=1786970944\" rel=\"nofollow\" class=\"text-link\"\u003e\u003cspan\u003eRead the full Single-Tube Saliva Collection Instructions\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":57881731924349,"sku":"SAL-CORT-AM","price":79.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Morning_Cortisol_Test.webp?v=1785073862"},{"product_id":"male-all-day-cortisol-test-lcms","title":"Male All Day Cortisol Test (LC-MS\/MS)","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e S-120 | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Saliva | \u003cstrong\u003eTechnology:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults Time:\u003c\/strong\u003e 3–5 Working Days After Laboratory Receives Sample | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eHormone Specialist Doctor Interpretation:\u003c\/strong\u003e Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children\u003c\/p\u003e\n\u003ch2\u003eWhat Does This Test Measure?\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSaliva — 4-Point Cortisol Profile (LC-MS\/MS):\u003c\/strong\u003e Morning Cortisol, Noon Cortisol, Evening Cortisol, Night Cortisol.\u003cbr\u003e4 markers — the complete daily adrenal rhythm for assessing the full cortisol curve, HPA axis function, and cortisol–testosterone interaction across the entire day in a single at-home saliva kit.\u003c\/p\u003e\n\u003ch2\u003eRelated Symptoms\u003c\/h2\u003e\n\u003cp\u003ePersistent fatigue or exhaustion that sleep does not resolve, difficulty waking or feeling unrefreshed in the morning, afternoon energy crashes, heavy reliance on caffeine, insomnia or night waking, low libido or erectile dysfunction, loss of muscle mass or poor gym recovery, unexplained abdominal fat gain, anxiety, irritability, low mood, brain fog, chronic stress or burnout, or symptoms of low testosterone with inconclusive standard blood results.\u003c\/p\u003e\n\u003ch2\u003eDid You Know?\u003c\/h2\u003e\n\u003cp\u003eA single morning cortisol reading identifies only one phase of the daily adrenal rhythm. For men, the clinically critical questions are: is cortisol suppressing testosterone synthesis during the day via pregnenolone steal? Is elevated evening cortisol preventing the testosterone and growth hormone surge that occurs in early sleep? Is high night cortisol destroying the deep sleep phases responsible for 70% of daily testosterone production? None of these questions can be answered by a single time point — they require the full four-point curve. The 4-point profile is the minimum required to identify which phase of the day is driving androgenic suppression, insulin resistance, visceral fat accumulation, or adrenal burnout.\u003c\/p\u003e\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003ePersistent fatigue or exhaustion that sleep does not resolve\u003c\/li\u003e\n\u003cli\u003eDifficulty waking in the morning or feeling unrefreshed despite adequate sleep\u003c\/li\u003e\n\u003cli\u003eAfternoon energy crashes or heavy reliance on caffeine to function\u003c\/li\u003e\n\u003cli\u003eInsomnia, night waking, or inability to switch off at bedtime\u003c\/li\u003e\n\u003cli\u003eLow libido or reduced sexual interest\u003c\/li\u003e\n\u003cli\u003eErectile dysfunction or reduced sexual performance\u003c\/li\u003e\n\u003cli\u003eLoss of muscle mass or poor recovery after training\u003c\/li\u003e\n\u003cli\u003eUnexplained abdominal fat gain despite exercise\u003c\/li\u003e\n\u003cli\u003eAnxiety, irritability, or low mood\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor focus, or reduced motivation\u003c\/li\u003e\n\u003cli\u003eSymptoms of low testosterone with normal or inconclusive standard blood results\u003c\/li\u003e\n\u003cli\u003eChronic stress, overtraining, or burnout\u003c\/li\u003e\n\u003cli\u003eCurrently on TRT and wanting to understand cortisol’s impact on treatment response\u003c\/li\u003e\n\u003cli\u003eMen wanting to identify exactly which phase of the day is driving their symptoms\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy This Test Is Particularly Important for Men\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eHigh morning cortisol acutely suppresses testosterone via pregnenolone steal and drives anxiety, elevated blood pressure, and poor recovery — a blunted morning cortisol signals adrenal burnout with profound fatigue and loss of drive\u003c\/li\u003e\n\u003cli\u003eElevated noon or afternoon cortisol drives insulin resistance, visceral fat accumulation, and increased aromatase activity — converting testosterone to estradiol and compounding androgenic decline throughout the day\u003c\/li\u003e\n\u003cli\u003eHigh evening cortisol prevents the natural testosterone and growth hormone surge that occurs in the early stages of sleep — one of the most common and clinically overlooked drivers of low morning testosterone in men\u003c\/li\u003e\n\u003cli\u003eElevated night cortisol directly suppresses the deep sleep phases during which the majority of daily testosterone is produced — causing insomnia, night waking, and chronically impaired testosterone synthesis regardless of total sleep duration\u003c\/li\u003e\n\u003cli\u003eA flat cortisol curve — seen in advanced burnout and chronic overtraining — is associated with total hormonal exhaustion and requires a different intervention to an elevated curve; the two patterns are indistinguishable from symptoms alone\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan\u003eSee \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/saliva-4-point-cortisol.pdf?v=1786976487\" title=\"All Day Cortisol Test Result Sample\"\u003e\u003cstrong\u003eAll Day Cortisol Sample Report (4 Point Cortisol)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca href=\"mailto:info@hormonelab.co.uk\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours.\u003c\/p\u003e\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered directly to your door\u003c\/li\u003e\n\u003cli\u003eCollect saliva at four time points: morning (within 30 minutes of waking, before 9am), noon, evening, and night — following the detailed instructions provided\u003c\/li\u003e\n\u003cli\u003ePost your samples to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your full report by email within 3–5 working days\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll four cortisol readings with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eVisual chart showing your complete daily cortisol rhythm curve\u003c\/li\u003e\n\u003cli\u003eWritten interpretation by a Hormone Specialist PhD Doctor including cortisol–testosterone interaction assessment and phase-specific androgenic impact analysis\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePioneers of at-home \u003cstrong\u003edried blood spot (DBS)\u003c\/strong\u003e and saliva hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePersonalised reference ranges based on age and sex\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThrough our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to people across the UK and Europe — from the comfort of home.\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhy measure cortisol at four points rather than just the morning?\u003c\/strong\u003e\u003cbr\u003eEach time point has distinct androgenic and metabolic consequences. Morning cortisol assesses the Cortisol Awakening Response and testosterone suppression risk; noon assesses insulin resistance and aromatase drive; evening assesses whether cortisol is preventing the testosterone surge in early sleep; night assesses whether deep-sleep testosterone synthesis is being suppressed. A single reading cannot identify which phase is responsible for a man’s symptoms.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan I use this test if I am on TRT?\u003c\/strong\u003e\u003cbr\u003eYes. This test is particularly valuable for men on TRT wanting to understand whether cortisol dysregulation is undermining the effectiveness of their testosterone therapy or causing residual symptoms.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDo I need to fast before collecting?\u003c\/strong\u003e\u003cbr\u003eNo fasting is required. Collect each sample according to the time point instructions provided in your kit.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eShould I start with just the morning cortisol test instead?\u003c\/strong\u003e\u003cbr\u003eThe morning test is an appropriate first step if your symptoms are primarily morning-focused. If you have symptoms across different parts of the day — afternoon crashes, evening anxiety, or night waking — the 4-point profile is the more appropriate assessment and avoids the need for a second test.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. There are no additional charges. You are only responsible for posting your samples to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e\n\u003ch2 data-pm-slice=\"1 1 []\"\u003e\u003cstrong\u003eSaliva Sample Collection Instructions\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eCollect your saliva samples at home using the materials supplied with your kit. \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eCheck your Test Requisition Form and kit instructions to confirm whether you need one, two or four samples.\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e You may not need every tube supplied.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRead all instructions before collection, including the \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eHormone Users\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e section if you take hormone treatment.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003e1. Confirm Your Collection Times\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003e\u003cspan\u003eNumber of samples required\u003c\/span\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cspan\u003eCollection times\u003c\/span\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eOne\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eMorning\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eTwo\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eMorning and before bed\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eFour\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eMorning, before lunch, before dinner and before bed\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cspan\u003eUse the \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003elarge 10 mL tube for your morning sample\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e and the \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003esmaller 5 mL tubes for later samples\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003e2. Choose Your Collection Day\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eChoose your collection day and mark it on your calendar. Record all current medicines on your Test Requisition Form.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMen, children and women who do not menstruate:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Collect on any day of the month, following the hormone-treatment instructions below where applicable.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eWomen who menstruate:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e If testing estradiol, progesterone or testosterone, follow this schedule:\u003c\/span\u003e\u003c\/p\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003e\u003cspan\u003eYour usual menstrual-cycle length\u003c\/span\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cspan\u003eWhen to collect\u003c\/span\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003e23–26 days\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eDay 17, 18 or 19\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003e27–30 days\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eDay 21, 22 or 23\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003e31–34 days\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eDay 25, 26 or 27\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eShorter or longer regular cycles\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e5–7 days before your next expected period\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eInfrequent or unpredictable cycles\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eAny non-bleeding day\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eDay 1 is the first day of menstrual flow, not spotting.\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Ovulation timing varies with cycle length.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003e3. Hormone Users\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eSkip this section if you do not use hormones.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eList all hormone treatments on your requisition form.\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e This information helps the laboratory select appropriate reference ranges and provide relevant comments.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eContinue prescribed hormone treatment.\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e If the collection instructions require a change to your usual dosing time, confirm the timing with your prescriber.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch4\u003e\u003cspan\u003eTopical and Oral Hormones\u003c\/span\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eContinue your prescribed hormones on the day before testing.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eThe laboratory specifies \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eat least 12 hours between an evening dose and morning collection\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e. For example, an 8 am collection requires the previous evening’s dose by 8 pm.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eOral progesterone is an exception:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e it may be taken immediately before bed.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eFor at least \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003etwo days before collection\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, use gloves or an applicator when applying topical hormones rather than bare hands.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eAvoid applying hormones to the \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eface, lips or neck\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003eTroches or Under-the-Tongue Hormones\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003e\u003cspan\u003eThese treatments are \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003enot recommended for saliva hormone testing\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e because they can contaminate samples. Discuss an alternative, such as blood spot testing, with your healthcare professional. Samples may be fully or partially rejected.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003ePatches, Vaginal Rings, Pellets or Injections\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003e\u003cspan\u003eThe laboratory advises testing \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003ehalfway between doses\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e. Examples include approximately three days after a once-weekly patch or two weeks after a once-monthly injection.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eConfirm the appropriate timing for your particular treatment with your prescriber.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003eSteroid Medicines\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003e\u003cspan\u003eIf you use glucocorticoids, including \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003ehydrocortisone or prednisone\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, ask your healthcare professional about collection timing.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003ePrevent Hormone Contamination\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eChange your \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003esheets, pillowcases and towels\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e the night before collection.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAvoid touching bathroom surfaces that may contain hormone residue.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eDry your washed hands with a clean towel.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003e4. Prepare for Collection\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eThree days before collection\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eAvoid anti-ageing or anti-wrinkle facial creams and biotin\/vitamin B7 supplements, including hair and nail formulas.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eThe night before collection\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eStay normally hydrated without drinking excessive amounts. Both dehydration and overhydration can affect salivary hormone measurements.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBefore your morning sample\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eDo not eat, drink anything except water, or brush your teeth.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBefore any later samples\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eDo not eat, drink anything except water, or brush your teeth for at least \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003etwo hours before collection\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003e5. Collect Your Samples\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eWash your hands\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e with soap and water, then dry them with a clean towel.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eRinse your mouth with water\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e and wait \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003efive minutes\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eBegin your morning collection within 30 minutes of waking\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, using the large tube.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAllow saliva to pool naturally in your mouth, then transfer it into the tube.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eFill the tube \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eat least halfway, excluding bubbles\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e. Collection usually takes \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003e15–30 minutes\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, depending on saliva flow.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eScrew the cap on securely.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eLabel the tube with your \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003ename, collection date and collection time\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, then return it to its bag.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eRepeat these steps at any later required collection times, using the smaller tubes.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTo encourage saliva flow:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Try yawning, smelling food without eating it, or pressing the tip of your tongue against your teeth. Gently tap the tube on a hard surface to help remove bubbles.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003e6. Complete Your Paperwork and Return Your Samples\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eComplete your requisition form fully, including your symptoms, medical history, medicines and hormone treatments.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003ePlace your labelled samples, requisition form and any additional paperwork inside the plastic test kit box.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eInclude payment only if applicable under your kit’s arrangements.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eSnap the box lid shut and place the entire box inside the return packaging.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAttach a prepaid label if supplied and applicable, or arrange the required postage.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eReturn the package using the carrier specified in your kit instructions.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003e7. Storage and Collection Mistakes\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFreeze any samples that will not be shipped within 24 hours.\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e The laboratory states that samples remain stable under average shipping conditions, including weekends and holidays.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIf you make a collection mistake, rinse the affected tube with \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003ehot water only—no soap\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e. Shake out the remaining water, allow it to air-dry and restart collection at the appropriate time.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eBefore packing, check that \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eevery sample tube is at least halfway full of liquid saliva, excluding bubbles\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Saliva_Collection_Instructions.pdf?v=1786970945\"\u003eRead the full Saliva Collection Instructions\u003c\/a\u003e.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":57881785893245,"sku":"SAL-CORT-4PT","price":185.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Saliva_Hormone_Panel_Test.png?v=1785073869"},{"product_id":"lcms-7-hormone-saliva-test-panel-1","title":"Male Saliva Hormone Profile II (LC-MS\/MS)","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e S-140 | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Saliva | \u003cstrong\u003eTechnology:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults Time:\u003c\/strong\u003e 3–5 Working Days After Laboratory Receives Sample | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eHormone Specialist Doctor Interpretation:\u003c\/strong\u003e Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\n\u003ch2\u003eWhat Does This Test Measure?\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSaliva — Expanded Male Hormone Panel (LC-MS\/MS):\u003c\/strong\u003e Testosterone, Estradiol (E2), Progesterone, Morning Cortisol, Noon Cortisol, Evening Cortisol, Night Cortisol.\u003cbr\u003e\n7 markers — extending the core androgenic assessment with a full 4-point diurnal cortisol curve, revealing how stress and HPA axis function are shaping testosterone output, recovery, and adrenal regulation throughout the day.\u003c\/p\u003e\n\n\u003ch2\u003eRelated Symptoms\u003c\/h2\u003e\n\u003cp\u003eLow libido or erectile dysfunction, persistent fatigue or low energy, loss of muscle mass or poor gym recovery, increased body fat particularly around the abdomen or chest, poor sleep or night waking, low mood, anxiety, irritability, brain fog, reduced motivation, burnout or overtraining, afternoon energy crashes, evening anxiety or racing thoughts, or symptoms of low testosterone with normal standard blood test results.\u003c\/p\u003e\n\n\u003ch2\u003eDid You Know?\u003c\/h2\u003e\n\u003cp\u003eA single morning cortisol reading — as measured in standard blood panels — cannot reveal how cortisol behaves across the day. It cannot detect elevated noon cortisol driving visceral fat and insulin resistance, elevated evening cortisol blocking testosterone synthesis during sleep, or elevated night cortisol suppressing the deep sleep phases responsible for the majority of daily testosterone production. The 4-point cortisol curve in this panel captures all of these patterns. When assessed alongside testosterone, estradiol, and progesterone, it provides the most complete picture of how the HPA axis is shaping androgenic status available from a single at-home saliva test.\u003c\/p\u003e\n\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eLow libido or reduced sexual interest\u003c\/li\u003e\n\u003cli\u003eErectile dysfunction or reduced sexual performance\u003c\/li\u003e\n\u003cli\u003ePersistent fatigue or low energy despite adequate sleep\u003c\/li\u003e\n\u003cli\u003eLoss of muscle mass or difficulty building strength\u003c\/li\u003e\n\u003cli\u003eIncreased body fat, especially around the abdomen or chest\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor concentration, or reduced motivation\u003c\/li\u003e\n\u003cli\u003eLow mood, irritability, anxiety, or depression\u003c\/li\u003e\n\u003cli\u003ePoor sleep quality, night waking, or insomnia\u003c\/li\u003e\n\u003cli\u003eAfternoon energy crashes or mid-day fatigue\u003c\/li\u003e\n\u003cli\u003eEvening anxiety, restlessness, or difficulty switching off\u003c\/li\u003e\n\u003cli\u003eSymptoms of andropause, typically from age 35+\u003c\/li\u003e\n\u003cli\u003eBurnout, overtraining, or sustained high physical or psychological stress\u003c\/li\u003e\n\u003cli\u003ePlateaued training performance or poor recovery despite adequate rest\u003c\/li\u003e\n\u003cli\u003eCurrently on TRT and wanting to monitor estradiol conversion and full cortisol rhythm\u003c\/li\u003e\n\u003cli\u003eFeeling hormonally off but told results are normal on standard blood tests\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy This Test Is Particularly Important for Men\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eThe 4-point cortisol curve reveals the full HPA axis pattern that a single morning reading cannot — elevated noon cortisol drives visceral fat and insulin resistance; elevated evening cortisol suppresses progesterone and testosterone precursor synthesis; elevated night cortisol directly suppresses the deep sleep phases responsible for the majority of daily testosterone production\u003c\/li\u003e\n\u003cli\u003eSaliva LC-MS\/MS measures free, bioavailable testosterone — the fraction actually reaching cells and driving libido, muscle, and mood; a man with high SHBG can have normal total blood testosterone but critically low free testosterone with full androgenic deficiency symptoms\u003c\/li\u003e\n\u003cli\u003eEstradiol must be measured alongside testosterone — excess estradiol from aromatase-driven conversion suppresses HPG axis testosterone output, causes gynaecomastia, and drives water retention; the testosterone-to-estradiol ratio is the most actionable number in this panel\u003c\/li\u003e\n\u003cli\u003eProgesterone is the natural aromatase inhibitor in men — low progesterone allows unchecked testosterone-to-estradiol conversion and is frequently the hidden driver of oestrogen dominance symptoms in men with plausible testosterone values\u003c\/li\u003e\n\u003cli\u003eThe cortisol-to-testosterone ratio across the full day is the most clinically informative marker of overtraining, adrenal-driven androgenic suppression, and burnout — a pattern invisible to any single time-point measurement\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca href=\"mailto:info@hormonelab.co.uk\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours.\u003c\/p\u003e\n\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered directly to your door\u003c\/li\u003e\n\u003cli\u003eCollect four saliva samples across the day — morning (7–9am), noon, evening, and night — following the detailed instructions provided; the morning sample should be collected before eating, drinking, or brushing your teeth\u003c\/li\u003e\n\u003cli\u003ePost your samples to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your full report by email within 3–5 working days\u003c\/li\u003e\n\u003c\/ol\u003e\n\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eTestosterone, Estradiol (E2), Progesterone, and 4-point Cortisol results with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eFull diurnal cortisol curve graph\u003c\/li\u003e\n\u003cli\u003eTestosterone-to-estradiol ratio, cortisol-to-testosterone ratio, and progesterone–estradiol balance assessment by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePioneers of at-home \u003cstrong\u003edried blood spot (DBS)\u003c\/strong\u003e and saliva hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePersonalised reference ranges based on age and sex\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThrough our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to people across the UK and Europe — from the comfort of home.\u003c\/p\u003e\n\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhat hormones does this test measure?\u003c\/strong\u003e\u003cbr\u003eTestosterone, Estradiol (E2), Progesterone, and Cortisol at four time points (morning, noon, evening, night) — 7 markers providing a complete androgenic and HPA axis assessment.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhen should I collect my samples?\u003c\/strong\u003e\u003cbr\u003eFour saliva samples are collected across the day: morning (ideally 7–9am, before eating or drinking), noon, evening, and night. Full collection instructions are included in your kit.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan I use this test if I am on TRT?\u003c\/strong\u003e\u003cbr\u003eYes. This test is particularly valuable for men on TRT wanting to monitor estradiol conversion and assess how the full cortisol rhythm is interacting with testosterone therapy.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow does this differ from Male Saliva Hormone Profile I?\u003c\/strong\u003e\u003cbr\u003eProfile I measures five markers including DHEAS and a single morning cortisol. Profile II replaces DHEAS with a full 4-point diurnal cortisol curve — providing complete visibility of how cortisol behaves throughout the day and its impact on testosterone synthesis, recovery, and adrenal regulation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. There are no additional charges. You are only responsible for posting your samples to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":57881876169085,"sku":"SAL-MALE-II","price":279.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Saliva_Hormone_Test.png?v=1785073883"},{"product_id":"male-cortisol-awakening-response-car-test","title":"Male Cortisol Awakening Response (CAR) Test (LC-MS\/MS)","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e S-122 | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Saliva | \u003cstrong\u003eTechnology:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults Time:\u003c\/strong\u003e 3–5 Working Days After Laboratory Receives Sample | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eHormone Specialist Doctor Interpretation:\u003c\/strong\u003e Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children\u003c\/p\u003e\n\u003ch2\u003eWhat Does This Test Measure?\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSaliva — Cortisol Awakening Response + Full Adrenal Profile (LC-MS\/MS):\u003c\/strong\u003e Cortisol Upon Waking, Cortisol +30 Minutes, Cortisol +60 Minutes, Midday Cortisol, Evening Cortisol, Night Cortisol, DHEAS.\u003cbr\u003e7 markers — the most detailed adrenal assessment available at home, capturing the full morning CAR window, the complete daily cortisol rhythm, and the primary adrenal testosterone precursor in a single saliva kit.\u003c\/p\u003e\n\u003ch2\u003eRelated Symptoms\u003c\/h2\u003e\n\u003cp\u003eWaking exhausted despite adequate sleep, anxiety or restlessness immediately on waking, persistent fatigue or low energy that does not improve with rest, insomnia or night waking, low libido or erectile dysfunction, loss of muscle mass or poor gym recovery, unexplained abdominal fat gain, anxiety, irritability, low mood, brain fog, chronic stress or burnout, symptoms of low testosterone with inconclusive standard blood results, or suspected adrenal fatigue or HPA axis dysfunction.\u003c\/p\u003e\n\u003ch2\u003eDid You Know?\u003c\/h2\u003e\n\u003cp\u003eThe Cortisol Awakening Response — the 50% cortisol surge that occurs within 30 minutes of waking — is the most clinically informative single window into HPA axis function available from non-invasive testing. For men, the shape of this morning curve directly determines: how much testosterone suppression via pregnenolone steal occurs during the day; how effectively deep sleep-based testosterone synthesis proceeds at night; and how resilient the androgenic system is to physical and psychological stress. A blunted CAR (flat morning curve) is the definitive marker of adrenal burnout and chronic overtraining. An exaggerated CAR signals acute HPA hyperreactivity with immediate testosterone suppression. Neither pattern is detectable from a single morning time point — the three-sample CAR window is required to distinguish them, and both are missed entirely by standard blood panels.\u003c\/p\u003e\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eWaking exhausted despite adequate sleep\u003c\/li\u003e\n\u003cli\u003eAnxiety, restlessness, or a sense of pressure immediately upon waking\u003c\/li\u003e\n\u003cli\u003ePersistent fatigue or low energy that does not improve with rest\u003c\/li\u003e\n\u003cli\u003eInsomnia, night waking, or inability to switch off at bedtime\u003c\/li\u003e\n\u003cli\u003eLow libido or reduced sexual interest\u003c\/li\u003e\n\u003cli\u003eErectile dysfunction or reduced sexual performance\u003c\/li\u003e\n\u003cli\u003eLoss of muscle mass or poor recovery after training\u003c\/li\u003e\n\u003cli\u003eUnexplained abdominal fat gain despite exercise\u003c\/li\u003e\n\u003cli\u003eAnxiety, irritability, or low mood\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor focus, or reduced motivation\u003c\/li\u003e\n\u003cli\u003eSymptoms of low testosterone with normal or inconclusive standard blood results\u003c\/li\u003e\n\u003cli\u003eChronic stress, overtraining, or burnout\u003c\/li\u003e\n\u003cli\u003eCurrently on TRT and wanting a complete adrenal picture\u003c\/li\u003e\n\u003cli\u003eSuspected adrenal fatigue or HPA axis dysfunction\u003c\/li\u003e\n\u003cli\u003eMen wanting the most detailed cortisol assessment available before considering clinical intervention\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy This Test Is Particularly Important for Men\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eThe three-sample CAR window (waking, +30 min, +60 min) is the only way to distinguish a blunted CAR from an exaggerated CAR — clinically opposite patterns that cause similar symptoms but require completely different interventions; a single morning reading cannot make this distinction\u003c\/li\u003e\n\u003cli\u003eThe morning cortisol surge directly determines testosterone suppression magnitude via pregnenolone steal — men with an exaggerated CAR lose the highest proportion of testosterone precursor to cortisol during the hours when androgenic drive for the day is set\u003c\/li\u003e\n\u003cli\u003eDHEAS is the primary adrenal testosterone precursor in men — combined with the CAR pattern, the DHEAS-to-cortisol relationship provides the most complete assessment of adrenal-driven androgenic status available from a single at-home test\u003c\/li\u003e\n\u003cli\u003eElevated evening and night cortisol directly suppress the deep sleep phases responsible for the majority of daily testosterone production — the full 6-point profile identifies whether this nocturnal suppression is present and at which time point it begins\u003c\/li\u003e\n\u003cli\u003eFor men on TRT, the CAR test identifies whether adrenal dysfunction is the reason TRT is underperforming — cortisol dysregulation and DHEAS deficiency are the most common causes of residual androgenic deficiency symptoms despite adequate testosterone dosing\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca href=\"mailto:info@hormonelab.co.uk\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours.\u003c\/p\u003e\n\u003ch2\u003eCollection Protocol\u003c\/h2\u003e\n\u003cp\u003eSix saliva samples collected across the day:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSample 1:\u003c\/strong\u003e Within 5 minutes of waking — before getting out of bed, ideally 6–8am\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSample 2:\u003c\/strong\u003e 30 minutes after waking\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSample 3:\u003c\/strong\u003e 60 minutes after waking\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSample 4:\u003c\/strong\u003e Midday\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSample 5:\u003c\/strong\u003e Evening\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSample 6:\u003c\/strong\u003e Night (before sleep)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFull collection instructions are included in the kit. The three morning samples must be collected at exact intervals — do not eat, drink, or brush your teeth before completing all three.\u003c\/p\u003e\n\u003cp\u003eSee \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Saliva_Cortisol_Awakening_Response_CAR_Collection_Kit.pdf?v=1786970943\" title=\"Cortisol Awakening Response Sample Collection Instructions\"\u003e\u003cstrong\u003eCortisol Awakening Response Test Sample Collection Instruction\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered directly to your door\u003c\/li\u003e\n\u003cli\u003eCollect six saliva samples across the day following the detailed instructions provided\u003c\/li\u003e\n\u003cli\u003ePost your samples to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your full report by email within 3–5 working days\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll six cortisol readings and DHEAS with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eFull diurnal cortisol curve graph including the complete CAR window\u003c\/li\u003e\n\u003cli\u003eWritten interpretation by a Hormone Specialist PhD Doctor including CAR pattern classification, cortisol–testosterone impact assessment, and DHEAS adrenal reserve evaluation\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSee \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/saliva-cortisol-awakening-response.pdf?v=1786976488\" title=\"Cortisol Awakening Response Test Result Sample\"\u003e\u003cstrong\u003eCortisol Awakening Response Test Result Sample\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePioneers of at-home \u003cstrong\u003edried blood spot (DBS)\u003c\/strong\u003e and saliva hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePersonalised reference ranges based on age and sex\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThrough our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to people across the UK and Europe — from the comfort of home.\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhat does this test measure?\u003c\/strong\u003e\u003cbr\u003eCortisol at six time points (waking, +30 min, +60 min, midday, evening, night) and DHEAS — 7 markers providing the most detailed adrenal and HPA axis assessment available from a single at-home saliva test.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is the CAR particularly important for men?\u003c\/strong\u003e\u003cbr\u003eThe morning cortisol surge directly determines testosterone suppression via pregnenolone steal during the day and the quality of sleep-based testosterone synthesis at night. The three-sample CAR window is the only method that can distinguish a blunted from an exaggerated CAR — two opposite patterns with different clinical implications that a single morning reading cannot differentiate.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan I use this test if I am on TRT?\u003c\/strong\u003e\u003cbr\u003eYes. This test is particularly valuable for men on TRT wanting to understand whether adrenal dysfunction — including CAR dysregulation and DHEAS deficiency — is undermining the effectiveness of testosterone therapy.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDo I need to fast before collecting?\u003c\/strong\u003e\u003cbr\u003eNo fasting is required. Follow the timing instructions carefully — particularly for the three morning samples, which must be collected at exact intervals and before eating, drinking, or brushing your teeth.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. There are no additional charges. You are only responsible for posting your samples to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":57881904841085,"sku":"SAL-CAR-01","price":219.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Saliva_Hormone_Panel_Test.png?v=1785073869"},{"product_id":"lcms-5-hormone-saliva-test-panel-1","title":"Male Saliva Hormone Profile I (LC-MS\/MS)","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e S-124 | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Saliva | \u003cstrong\u003eTechnology:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults Time:\u003c\/strong\u003e 3–5 Working Days After Laboratory Receives Sample | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eHormone Specialist Doctor Interpretation:\u003c\/strong\u003e Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\n\u003ch2\u003eWhat Does This Test Measure?\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSaliva — Core Male Hormone Panel (LC-MS\/MS):\u003c\/strong\u003e Testosterone, Estradiol (E2), DHEAS, Progesterone, Cortisol.\u003cbr\u003e\n5 markers — the foundational male hormonal assessment covering androgenic status, adrenal reserve, oestrogen balance, and the cortisol–testosterone relationship in a single at-home saliva kit.\u003c\/p\u003e\n\n\u003ch2\u003eRelated Symptoms\u003c\/h2\u003e\n\u003cp\u003eLow libido or erectile dysfunction, persistent fatigue or low energy, loss of muscle mass or poor gym recovery, increased body fat particularly around the abdomen or chest, poor sleep or night waking, low mood, anxiety, irritability, brain fog, reduced motivation, gynaecomastia or breast tenderness, burnout or overtraining, or symptoms of low testosterone with normal standard blood test results.\u003c\/p\u003e\n\n\u003ch2\u003eDid You Know?\u003c\/h2\u003e\n\u003cp\u003eStandard NHS blood testosterone panels measure total testosterone by immunoassay — including the protein-bound fraction unavailable to cells. Saliva LC-MS\/MS measures free, bioavailable testosterone, the fraction actually reaching tissues and driving androgenic function. A man with elevated SHBG can have a normal total blood testosterone result with critically low free testosterone and full androgenic deficiency symptoms. This profile extends that assessment to include DHEAS — the adrenal testosterone precursor — and cortisol, revealing whether adrenal dysfunction and HPA axis dysregulation are contributing to the androgenic picture. Progesterone in men acts as a natural aromatase inhibitor, directly regulating testosterone-to-estradiol conversion — a mechanism completely absent from standard blood panel evaluation.\u003c\/p\u003e\n\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eLow libido or reduced sexual interest\u003c\/li\u003e\n\u003cli\u003eErectile dysfunction or reduced sexual performance\u003c\/li\u003e\n\u003cli\u003ePersistent fatigue or low energy despite adequate sleep\u003c\/li\u003e\n\u003cli\u003eLoss of muscle mass or difficulty building strength\u003c\/li\u003e\n\u003cli\u003eIncreased body fat, especially around the abdomen or chest\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor concentration, or reduced motivation\u003c\/li\u003e\n\u003cli\u003eLow mood, irritability, anxiety, or depression\u003c\/li\u003e\n\u003cli\u003ePoor sleep quality or difficulty staying asleep\u003c\/li\u003e\n\u003cli\u003eSymptoms of andropause, typically from age 35+\u003c\/li\u003e\n\u003cli\u003eGynaecomastia or breast tenderness\u003c\/li\u003e\n\u003cli\u003eBurnout, overtraining, or sustained high physical or psychological stress\u003c\/li\u003e\n\u003cli\u003ePlateaued training performance or poor recovery despite adequate rest\u003c\/li\u003e\n\u003cli\u003eCurrently on TRT and wanting to monitor estradiol conversion and adrenal balance\u003c\/li\u003e\n\u003cli\u003eFeeling hormonally off but told results are normal on standard blood tests\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy This Test Is Particularly Important for Men\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSaliva LC-MS\/MS measures free, bioavailable testosterone — the fraction actually reaching cells and driving libido, muscle, and mood; a man with high SHBG can have normal total blood testosterone but critically low free testosterone with full androgenic deficiency symptoms\u003c\/li\u003e\n\u003cli\u003eDHEAS is the primary adrenal testosterone precursor in men — its inclusion reveals whether adrenal depletion is contributing to androgenic decline independently of HPG axis function, a distinction that standard panels never make\u003c\/li\u003e\n\u003cli\u003eCortisol and testosterone are assessed together — the cortisol-to-testosterone ratio is the most clinically useful marker of overtraining and stress-driven androgenic suppression available from a single test\u003c\/li\u003e\n\u003cli\u003eEstradiol must be measured alongside testosterone — excess estradiol from aromatase-driven conversion suppresses HPG axis testosterone output, causes gynaecomastia, and drives water retention; the testosterone-to-estradiol ratio is the most actionable number in this panel\u003c\/li\u003e\n\u003cli\u003eProgesterone is the natural aromatase inhibitor in men — low progesterone allows unchecked testosterone-to-estradiol conversion and is frequently the hidden driver of oestrogen dominance symptoms in men with plausible testosterone values\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca href=\"mailto:info@hormonelab.co.uk\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours.\u003c\/p\u003e\n\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered directly to your door\u003c\/li\u003e\n\u003cli\u003eCollect your saliva sample in the morning (ideally 7–9am), when testosterone is naturally at its peak, before eating, drinking, or brushing your teeth\u003c\/li\u003e\n\u003cli\u003ePost your sample to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your full report by email within 3–5 working days\u003c\/li\u003e\n\u003c\/ol\u003e\n\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eTestosterone, Estradiol (E2), DHEAS, Progesterone, and Cortisol results with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eVisual charts for all five hormones\u003c\/li\u003e\n\u003cli\u003eTestosterone-to-estradiol ratio, cortisol-to-testosterone ratio, and progesterone–estradiol balance assessment by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePioneers of at-home \u003cstrong\u003edried blood spot (DBS)\u003c\/strong\u003e and saliva hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePersonalised reference ranges based on age and sex\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThrough our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to people across the UK and Europe — from the comfort of home.\u003c\/p\u003e\n\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhat hormones does this test measure?\u003c\/strong\u003e\u003cbr\u003eTestosterone, Estradiol (E2), DHEAS, Progesterone, and Cortisol — five markers covering androgenic status, adrenal reserve, oestrogen balance, and the cortisol–testosterone relationship.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhen should I collect my sample?\u003c\/strong\u003e\u003cbr\u003eCollect in the morning, ideally between 7–9am, when testosterone is naturally at its daily peak. Full collection instructions are included in your kit.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan I use this test if I am on TRT?\u003c\/strong\u003e\u003cbr\u003eYes. This test is particularly valuable for men on TRT wanting to monitor estradiol conversion, DHEAS adrenal reserve, and cortisol balance alongside their testosterone levels.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIs this test useful for athletes or men concerned about overtraining?\u003c\/strong\u003e\u003cbr\u003eYes. The cortisol-to-testosterone ratio is the most clinically informative marker of overtraining and under-recovery available from a single test, and DHEAS provides additional context on adrenal reserve under sustained training load.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is saliva better than blood for these hormones?\u003c\/strong\u003e\u003cbr\u003eSaliva LC-MS\/MS measures free, bioavailable hormone — the fraction actually active at the cellular level. Standard blood tests measure total hormone including the protein-bound inactive fraction, which can mask clinically significant imbalances.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. There are no additional charges. You are only responsible for posting your sample to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":57881920045437,"sku":"SAL-MALE-I","price":220.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Saliva_Hormone_Test.png?v=1785073883"},{"product_id":"lcms-7-hormone-saliva-test-panel-for-men","title":"Male Saliva Hormone Profile III (LC-MS\/MS)","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e S-125 | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Saliva | \u003cstrong\u003eTechnology:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults Time:\u003c\/strong\u003e 3–5 Working Days After Laboratory Receives Sample | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eHormone Specialist Doctor Interpretation:\u003c\/strong\u003e Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\n\u003ch2\u003eWhat Does This Test Measure?\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSaliva — Advanced Male Hormone Panel (LC-MS\/MS):\u003c\/strong\u003e Testosterone, DHEAS, Progesterone, Cortisol, Estrone (E1), Estradiol (E2), Estriol (E3).\u003cbr\u003e\n7 markers — the most complete single-point oestrogen assessment available in a male saliva panel, combining the full oestrogen triad with androgenic status, adrenal reserve, and morning cortisol in a single at-home kit.\u003c\/p\u003e\n\n\u003ch2\u003eRelated Symptoms\u003c\/h2\u003e\n\u003cp\u003eLow libido or erectile dysfunction, persistent fatigue or low energy, loss of muscle mass or poor gym recovery, increased body fat particularly around the abdomen or chest, poor sleep or night waking, low mood, anxiety, brain fog, reduced motivation, gynaecomastia or breast tenderness, water retention, burnout or chronic stress, or symptoms of oestrogen excess with normal total testosterone on standard blood results.\u003c\/p\u003e\n\n\u003ch2\u003eDid You Know?\u003c\/h2\u003e\n\u003cp\u003eMost male hormone panels measure only estradiol (E2) — the most potent oestrogen. This profile adds estrone (E1) and estriol (E3), providing the complete oestrogenic picture. Estrone is the primary oestrogen produced by adipose tissue and is the dominant oestrogen in men with higher body fat or elevated aromatase activity. Estriol provides context on overall oestrogenic load. The E1:E2:E3 ratio allows a clinically meaningful assessment of oestrogen source and metabolic conversion pathway — a level of detail that is impossible from E2 measurement alone, and that directly informs whether aromatase inhibition, progesterone support, or DHEAS optimisation is the appropriate clinical priority.\u003c\/p\u003e\n\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eLow libido or reduced sexual interest\u003c\/li\u003e\n\u003cli\u003eErectile dysfunction or reduced sexual performance\u003c\/li\u003e\n\u003cli\u003ePersistent fatigue or low energy despite adequate sleep\u003c\/li\u003e\n\u003cli\u003eLoss of muscle mass or difficulty building strength\u003c\/li\u003e\n\u003cli\u003eIncreased body fat, especially around the abdomen or chest\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor concentration, or reduced motivation\u003c\/li\u003e\n\u003cli\u003eLow mood, irritability, anxiety, or depression\u003c\/li\u003e\n\u003cli\u003ePoor sleep quality or difficulty staying asleep\u003c\/li\u003e\n\u003cli\u003eSymptoms of andropause, typically from age 35+\u003c\/li\u003e\n\u003cli\u003eGynaecomastia, breast tenderness, or water retention (signs of elevated oestrogenic activity)\u003c\/li\u003e\n\u003cli\u003eBurnout or sustained high psychological or physical stress\u003c\/li\u003e\n\u003cli\u003eCurrently on TRT and wanting a full oestrogen triad assessment alongside androgenic and adrenal markers\u003c\/li\u003e\n\u003cli\u003eFeeling hormonally off but told results are normal on standard blood tests\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy This Test Is Particularly Important for Men\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eThe full oestrogen triad (E1, E2, E3) reveals oestrogen source and metabolic conversion in men — estrone elevation relative to estradiol indicates adipose-driven aromatisation; the E1:E2 ratio guides whether dietary, lifestyle, or pharmacological aromatase management is appropriate\u003c\/li\u003e\n\u003cli\u003eSaliva LC-MS\/MS measures free, bioavailable testosterone and estradiol — the fractions actually reaching cells; a man with high SHBG can have normal total blood testosterone but critically low free testosterone with full androgenic deficiency symptoms, while simultaneously showing elevated free estradiol driving oestrogen dominance symptoms\u003c\/li\u003e\n\u003cli\u003eDHEAS is the primary adrenal testosterone precursor in men — its inclusion reveals whether adrenal depletion is contributing to androgenic decline and whether DHEAS supplementation may be an appropriate adjunct to direct testosterone support\u003c\/li\u003e\n\u003cli\u003eProgesterone is the natural aromatase inhibitor in men — low progesterone allows unchecked testosterone-to-estradiol conversion; its measurement alongside the full oestrogen triad identifies whether aromatase dysregulation is progesterone-mediated\u003c\/li\u003e\n\u003cli\u003eCortisol provides the HPA axis context — elevated morning cortisol drives pregnenolone steal, suppresses DHEAS production, and promotes visceral fat-driven aromatase activity; this pattern is the most common adrenal mechanism behind oestrogen dominance in men\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca href=\"mailto:info@hormonelab.co.uk\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours.\u003c\/p\u003e\n\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered directly to your door\u003c\/li\u003e\n\u003cli\u003eCollect your saliva sample in the morning (ideally 7–9am), when testosterone is naturally at its peak, before eating, drinking, or brushing your teeth\u003c\/li\u003e\n\u003cli\u003ePost your sample to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your full report by email within 3–5 working days\u003c\/li\u003e\n\u003c\/ol\u003e\n\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eTestosterone, DHEAS, Progesterone, Cortisol, Estrone (E1), Estradiol (E2), and Estriol (E3) results with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eVisual charts for all seven hormones\u003c\/li\u003e\n\u003cli\u003eFull oestrogen triad ratio analysis, testosterone-to-estradiol assessment, and adrenal–androgenic interaction evaluation by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePioneers of at-home \u003cstrong\u003edried blood spot (DBS)\u003c\/strong\u003e and saliva hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePersonalised reference ranges based on age and sex\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThrough our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to people across the UK and Europe — from the comfort of home.\u003c\/p\u003e\n\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhat hormones does this test measure?\u003c\/strong\u003e\u003cbr\u003eTestosterone, DHEAS, Progesterone, Cortisol, Estrone (E1), Estradiol (E2), and Estriol (E3) — 7 markers providing the most complete male oestrogen and androgenic panel available from a single at-home saliva test.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhen should I collect my sample?\u003c\/strong\u003e\u003cbr\u003eCollect in the morning, ideally between 7–9am, when testosterone is naturally at its daily peak. Full collection instructions are included in your kit.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow does this differ from Male Saliva Hormone Profile I?\u003c\/strong\u003e\u003cbr\u003eProfile I measures testosterone, estradiol, DHEAS, progesterone, and morning cortisol — 5 markers. Profile III extends this by adding estrone (E1) and estriol (E3), providing the complete oestrogen triad for a full assessment of oestrogenic source and metabolic conversion in men.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan I use this test if I am on TRT?\u003c\/strong\u003e\u003cbr\u003eYes. This test is particularly valuable for men on TRT wanting the most complete oestrogen picture alongside androgenic and adrenal markers to guide aromatase management and supplementation decisions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. There are no additional charges. You are only responsible for posting your sample to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":57881944457597,"sku":"SAL-MALE-III","price":299.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Saliva_Hormone_Test.png?v=1785073883"},{"product_id":"male-hormonal-acne-test-lcms","title":"Male Hormonal Acne Test (LCMS) | Specialist Doctor Report Included","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e S-124 | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Saliva | \u003cstrong\u003eTechnology:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults Time:\u003c\/strong\u003e 3–5 Working Days After Laboratory Receives Sample | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eHormone Specialist Doctor Interpretation:\u003c\/strong\u003e Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children\u003c\/p\u003e\n\u003ch2 data-pm-slice=\"1 1 []\"\u003e\u003cstrong\u003eWhat Does This Test Measure?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSaliva — Four Hormones (LC-MS\/MS): Estradiol (E2), Testosterone (T), Progesterone (Pg) and DHEAS (DS).\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThis at-home panel provides four salivary hormone measurements, with laboratory reference ranges and specialist comments to help explain your results.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTestosterone and DHEAS are the measurements most relevant to androgen-related acne.\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Estradiol and progesterone add hormone information acne in men.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eRelated Symptoms\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003ePersistent acne with oily skin\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAcne on the face, back, chest or shoulders\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAcne that appeared or worsened after starting testosterone treatment or using anabolic steroids\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eThese symptoms can involve androgen activity, but the location or severity of acne alone does not establish that hormone levels are high.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eDid You Know?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eAndrogens influence the skin’s oil glands. Testosterone and substances formed from adrenal androgens can contribute to increased oil production, which participates in acne development.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eHowever, acne can occur with hormone levels within the normal range because the skin’s sensitivity and local hormone processing also matter. This panel measures hormones in saliva; it does not measure DHT or androgen activity inside the skin.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eWho Should Consider This Test?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eMen seeking additional hormone information, particularly when:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003ePersistent acne is accompanied by marked skin oiliness\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAcne began or worsened following testosterone or anabolic-steroid use\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eA clinician has suggested investigating a possible hormonal contribution to acne\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003ePersistent acne that has not responded to treatment also deserves a review of the diagnosis and treatment plan. Hormone testing is not routinely needed for every man with acne.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eHow Your Results Can Help Guide Your Next Steps\u003c\/strong\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003ePersistent Acne and Oily Skin\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eRelevant measurements: Testosterone and DHEAS\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eYour results show whether these salivary measurements fall within the laboratory’s reference ranges. Specialist comments can highlight findings that deserve closer assessment.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eHow to use your results:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Read the comments alongside your symptoms and medication or supplement history. If a result is unexpectedly high or low, a clinician may recommend confirmatory blood testing. Results within range still leave effective acne-treatment options available.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eFor everyday care, use a gentle cleanser twice daily, choose non-comedogenic skincare and avoid picking spots. The hormone results add information; they do not determine which acne product will work best.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eAcne After Testosterone Treatment or Anabolic-Steroid Use\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eRelevant measurements: Testosterone and DHEAS, interpreted with your treatment history\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eTestosterone treatment and anabolic steroids can trigger or worsen acne. Record the exact products, doses and timing on your requisition form so the laboratory can interpret your measurements appropriately.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eHow to use your results:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Share the report with your prescriber if you use prescribed testosterone. Discuss acne treatment and any necessary monitoring rather than adjusting your hormone dose yourself. Acne can often be treated without stopping prescribed testosterone.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eAcne on the Back, Chest or Shoulders\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eRelevant measurements: Testosterone and DHEAS\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThese areas contain many oil glands and commonly develop acne. The measurements may add hormone information, but body acne is not proof of androgen excess.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eHow to use your results:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Review sweating, tight clothing, friction and oily products alongside your laboratory comments. Change out of sweaty clothing after exercise and use non-comedogenic products. Painful, extensive or scarring acne benefits from timely medical treatment.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eWhat Do Estradiol and Progesterone Add?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eThese results broaden the hormone profile, but neither a low progesterone result nor an Estradiol-to-testosterone ratio reliably identifies the cause of male acne.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIf you also have breast tenderness or enlargement, arrange a separate clinical assessment rather than assuming it is an acne-related hormone imbalance.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eHow the Specialist Comments Help\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eYour report explains the measured levels in the context of the information you provide. It can help you identify:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eWhich measurements fall outside the reference ranges\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eWhether medicines or supplements may affect interpretation\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eWhich findings warrant further investigation\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eThe practical benefit is additional hormone information and clearer questions for follow-up. Combine this with appropriate skincare and acne treatment, rather than using the results to select hormone supplements.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca href=\"mailto:info@hormonelab.co.uk\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours.\u003c\/p\u003e\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered directly to your door\u003c\/li\u003e\n\u003cli\u003eCollect your saliva sample following the detailed instructions provided in the kit\u003c\/li\u003e\n\u003cli\u003ePost your sample to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your full report by email within 3–5 working days\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll four hormone results with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eGraphical and numerical hormone data for easy interpretation\u003c\/li\u003e\n\u003cli\u003eWritten interpretation of your specific hormonal acne pattern by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003ePersonalised treatment and lifestyle guidance\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePioneers of at-home \u003cstrong\u003edried blood spot (DBS)\u003c\/strong\u003e and saliva hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePersonalised reference ranges based on age and sex\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThrough our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to people across the UK and Europe — from the comfort of home.\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhy saliva instead of blood?\u003c\/strong\u003e\u003cbr\u003eSaliva measures bioavailable (free, active) hormones — the fraction actually reaching your skin cells and sebaceous glands. Blood tests measure total hormone including the bound, inactive fraction, which can miss the imbalances most relevant to acne.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan I use this test if I am on TRT?\u003c\/strong\u003e\u003cbr\u003eYes. This test is particularly valuable for men on TRT experiencing acne as a side effect, as it reveals whether the issue is testosterone excess, oestradiol elevation from aromatisation, or progesterone insufficiency.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWill a specialist review my report?\u003c\/strong\u003e\u003cbr\u003eYes. A Hormone Specialist PhD Doctor adds personalised commentary to every report.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. There are no additional charges. You are only responsible for posting your samples to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e\n\u003cdiv class=\"product-single__description rte\" itemprop=\"description\"\u003e\n\u003ch2 data-pm-slice=\"1 1 []\"\u003e\u003cstrong\u003e\u003cspan\u003eSaliva Sample Collection Instructions\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eCollect your saliva samples at home using the materials provided in your kit. \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eCheck your Test Requisition Form and kit instructions to confirm whether your test requires one, two or four samples.\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e You may not need every tube supplied.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRead all instructions before you begin. If you use hormone treatment, also read the \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eHormone Users\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e section.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003e\u003cspan\u003e1. Check Your Collection Times\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cdiv class=\"rte__table-wrapper\"\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003e\u003cspan\u003eSamples required\u003c\/span\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cspan\u003eWhen to collect\u003c\/span\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eOne\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eMorning\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eTwo\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eMorning and before bed\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eFour\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eMorning, before lunch, before dinner and before bed\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cspan\u003eUse the \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003elarge 10 mL tube for your morning sample\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e and the \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003esmaller 5 mL tubes for any later samples\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e. Collect the required samples on the same day unless your kit instructions say otherwise.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003e\u003cspan\u003e2. Choose Your Collection Day\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eMark your collection day on your calendar. List all medicines, supplements and hormone treatments on your Test Requisition Form.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMen, children and women who do not menstruate:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Collect on any day of the month. If you use hormones, follow the treatment-timing instructions below.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eWomen who menstruate:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e If your test measures estradiol, progesterone or testosterone, use the following schedule:\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"rte__table-wrapper\"\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003e\u003cspan\u003eUsual menstrual-cycle length\u003c\/span\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cspan\u003eWhen to collect\u003c\/span\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003e23–26 days\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eDay 17, 18 or 19\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003e27–30 days\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eDay 21, 22 or 23\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003e31–34 days\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eDay 25, 26 or 27\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eShorter or longer regular cycles\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e5–7 days before your next expected period\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eInfrequent or unpredictable cycles\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eAny day when you are not bleeding\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eDay 1 is the first day of menstrual flow, not spotting.\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Follow any different timing instructions supplied for your particular test.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003e\u003cspan\u003e3. Hormone Users\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eSkip this section if you do not use hormones.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eRecord every hormone treatment on your Test Requisition Form.\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e This helps the laboratory choose suitable reference ranges and provide relevant comments.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eDo not stop prescribed hormone treatment for testing.\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e If collection requires changing your usual dosing time, check with your prescriber first.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003e\u003cspan\u003eTopical and Oral Hormones\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eContinue your prescribed treatment on the day before collection.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eAllow \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eat least 12 hours between an evening dose and your morning sample\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e. For example, if collecting at 8 am, take or apply the previous evening’s dose by 8 pm.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eOral progesterone is an exception:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e you may take it immediately before bed.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eFor at least \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003etwo days before collection\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, apply topical hormones using gloves or an applicator rather than bare hands.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eAvoid applying hormones to your \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eface, lips or neck\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003e\u003cspan\u003eTroches and Under-the-Tongue Hormones\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003e\u003cspan\u003eHormones that dissolve in the mouth can contaminate saliva samples. \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eSaliva hormone testing is not recommended while using these treatments.\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Ask your healthcare professional about an alternative, such as blood spot testing. Contaminated samples may be partially or fully rejected.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003e\u003cspan\u003ePatches, Vaginal Rings, Pellets and Injections\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003e\u003cspan\u003eThe laboratory advises collecting \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003ehalfway between doses or replacements\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e. For example, this may be approximately three days after applying a weekly patch or two weeks after a monthly injection.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eCheck the appropriate collection time for your particular treatment with your prescriber.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003e\u003cspan\u003eSteroid Medicines\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003e\u003cspan\u003eIf you take glucocorticoids, such as \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003ehydrocortisone or prednisone\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, ask your healthcare professional when to collect your samples.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003e\u003cspan\u003ePrevent Hormone Contamination\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003e\u003cspan\u003eTraces of hormone creams or gels can transfer from your hands, towels or household surfaces into your sample.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eChange your \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003esheets, pillowcases and towels\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e the night before collection.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAvoid touching bathroom surfaces that may contain hormone residue.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eWash your hands thoroughly and dry them with a clean towel.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003e\u003cspan\u003e4. Prepare for Collection\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eThree days before collection:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Avoid anti-ageing or anti-wrinkle facial creams and \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003ebiotin\/vitamin B7 supplements\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, including hair and nail formulas.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eThe night before collection:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Stay normally hydrated, but avoid drinking excessive amounts of fluid.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBefore your morning sample:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Do not eat, drink anything other than water, or brush your teeth.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBefore later samples:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Do not eat, drink anything other than water, or brush your teeth for at least \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003etwo hours before collection\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003e\u003cspan\u003e5. Collect Your Samples\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eWash your hands\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e with soap and water, then dry them with a clean towel.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003e\u003cspan\u003eRinse your mouth with water and wait five minutes.\u003c\/span\u003e\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan\u003eBegin your morning collection within 30 minutes of waking\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, using the large tube.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eLet saliva pool naturally in your mouth, then transfer it into the tube.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eFill the tube \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eat least halfway with liquid saliva, excluding bubbles\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e. This usually takes \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003e15–30 minutes\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, depending on saliva flow.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eScrew the cap on securely.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eLabel the tube with your \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003ename, collection date and collection time\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, then place it back in its bag.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eRepeat at each later collection time required for your test, using the smaller tubes.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eIf saliva flow is slow:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Try yawning, smelling food without eating it, or pressing the tip of your tongue against your teeth. To reduce bubbles, securely cap the tube and gently tap it on a hard surface.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003e\u003cspan\u003e6. Complete Your Paperwork and Pack Your Samples\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eComplete your Test Requisition Form, including your symptoms, medical history, medicines, supplements and hormone treatments.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eCheck that every required tube is \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eclearly labelled, securely closed and at least halfway full of liquid saliva\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003ePlace your samples, completed form and any additional paperwork inside the plastic kit box.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eInclude payment only if required under your kit’s arrangements.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eClose the box securely and place it inside the return packaging.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAttach the prepaid return label if provided, or arrange the required postage.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eReturn your samples using the carrier and return address specified in your kit instructions.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003e7. Storage and Collection Mistakes\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFreeze samples if you will not ship them within 24 hours of collection.\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Samples remain stable under average shipping conditions, including transit over weekends and holidays.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIf you need to repeat a collection, rinse the affected tube with \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003ehot water only—do not use soap\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e. Shake out the remaining water and leave the tube to air-dry before collecting again at the correct time.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIf you ate or brushed your teeth before collecting your morning sample, \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003erestart the following morning\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Saliva_Collection_Instructions.pdf?v=1786970945\" rel=\"nofollow\" class=\"text-link\"\u003e\u003cspan\u003eRead the full Saliva Collection Instructions\u003c\/span\u003e\u003c\/a\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":57882531529085,"sku":"SAL-ACNE-01","price":195.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Saliva_Hormone_Panel_Test.png?v=1785073869"},{"product_id":"men-s-weight-management-hormone-thyroid-metabolism-test-kit","title":"Male Weight Management Profile Test","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e SB-653 | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Saliva + Dried Blood Spot | \u003cstrong\u003eTechnology:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults Time:\u003c\/strong\u003e 3–5 Working Days After Laboratory Receives Sample | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eHormone Specialist Doctor Interpretation:\u003c\/strong\u003e Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\n\u003ch2\u003eWhat Does This Test Measure?\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSaliva — Sex Hormones (LC-MS\/MS):\u003c\/strong\u003e Estradiol (E2), Estriol (E3), Estrone (E1), Progesterone, Testosterone, DHEAS.\u003cbr\u003e\n\u003cstrong\u003eSaliva — 4-Point Cortisol Profile:\u003c\/strong\u003e Morning, Noon, Evening, and Night Cortisol.\u003cbr\u003e\n\u003cstrong\u003eBlood Spot — Full Thyroid Panel:\u003c\/strong\u003e TSH, Free T3, Free T4, Total T4, TPO Antibodies, Thyroglobulin Antibodies.\u003cbr\u003e\n\u003cstrong\u003eBlood Spot — CardioMetabolic Panel:\u003c\/strong\u003e Fasting Insulin, HbA1c, HDL Cholesterol, Triglycerides, Total Cholesterol, hsCRP.\u003cbr\u003e\n\u003cstrong\u003eBlood Spot — Vitamin D:\u003c\/strong\u003e 25-OH Vitamin D2, 25-OH Vitamin D3.\u003cbr\u003e\n26 markers total — the most comprehensive weight-focused at-home male health profile available in the UK, covering androgenic balance, the full daily cortisol rhythm, autoimmune thyroid function, cardiometabolic risk, and Vitamin D status in a single kit.\u003c\/p\u003e\n\n\u003ch2\u003eRelated Symptoms\u003c\/h2\u003e\n\u003cp\u003eUnexplained weight gain or difficulty losing weight despite diet and exercise, stubborn abdominal fat, slow metabolism, persistent fatigue, low energy, sugar cravings, energy crashes, poor sleep, low mood, low motivation, poor exercise recovery, chronic stress, burnout, hair thinning, feeling cold, or symptoms of low testosterone with normal standard blood results.\u003c\/p\u003e\n\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eUnexplained weight gain or difficulty losing weight despite consistent diet and exercise effort\u003c\/li\u003e\n\u003cli\u003eStubborn abdominal or visceral fat that does not respond to lifestyle changes\u003c\/li\u003e\n\u003cli\u003eSlow metabolism or persistent fatigue that does not improve with rest\u003c\/li\u003e\n\u003cli\u003eSugar cravings, energy crashes, or afternoon slumps\u003c\/li\u003e\n\u003cli\u003ePoor sleep quality, night waking, or unrefreshing sleep\u003c\/li\u003e\n\u003cli\u003eLow mood, low motivation, or reduced drive\u003c\/li\u003e\n\u003cli\u003ePoor exercise recovery or reduced physical performance\u003c\/li\u003e\n\u003cli\u003eChronic stress or burnout\u003c\/li\u003e\n\u003cli\u003eHair thinning, feeling cold, or dry skin alongside weight gain\u003c\/li\u003e\n\u003cli\u003eElevated cholesterol, triglycerides, or blood sugar on previous testing\u003c\/li\u003e\n\u003cli\u003eSymptoms of low testosterone with normal standard blood results\u003c\/li\u003e\n\u003cli\u003eMen wanting to understand the hormonal root causes of metabolic and weight challenges\u003c\/li\u003e\n\u003cli\u003eFamily history of thyroid disease, diabetes, heart disease, or metabolic syndrome\u003c\/li\u003e\n\u003cli\u003eMen over 35 experiencing unexplained changes in body composition\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy This Test Is Particularly Important for Men\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eCortisol is the primary hormonal driver of abdominal fat storage — directing visceral fat deposition, driving insulin resistance, suppressing testosterone via pregnenolone steal, and elevating hsCRP all simultaneously; the 4-point profile identifies which phase of the day is driving this cascade\u003c\/li\u003e\n\u003cli\u003eLow testosterone directly impairs metabolic rate and promotes abdominal fat accumulation — creating a self-reinforcing cycle with insulin resistance and aromatase-driven Estradiol (E2) excess that standard total testosterone blood tests frequently miss\u003c\/li\u003e\n\u003cli\u003eThyroid insufficiency slows metabolism independently of caloric intake — TSH alone misses cortisol-driven T3 suppression and Hashimoto’s autoimmunity, both of which produce weight gain and metabolic slowdown with a normal TSH\u003c\/li\u003e\n\u003cli\u003eFasting insulin is the earliest detectable marker of insulin resistance — elevated years before HbA1c becomes abnormal, directly linked to visceral fat, aromatase activity, and testosterone suppression\u003c\/li\u003e\n\u003cli\u003eVitamin D deficiency independently impairs testosterone synthesis, worsens insulin resistance, elevates hsCRP, and slows thyroid conversion — deficiency is prevalent in the UK and rarely tested alongside the hormonal markers that explain its metabolic impact\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca href=\"mailto:info@hormonelab.co.uk\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours.\u003c\/p\u003e\n\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered directly to your door\u003c\/li\u003e\n\u003cli\u003eCollect saliva at four time points (morning before 9am, noon, evening, night) and blood spot via finger-prick\u003c\/li\u003e\n\u003cli\u003ePost your samples to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your full report by email within 3–5 working days\u003c\/li\u003e\n\u003c\/ol\u003e\n\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll 26 marker results with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eVisual cortisol rhythm chart showing your full four-point daily curve\u003c\/li\u003e\n\u003cli\u003eVisual charts for all sex hormones, the full thyroid panel, all six cardiometabolic markers, and Vitamin D status\u003c\/li\u003e\n\u003cli\u003eIntegrated clinical interpretation of how cortisol, testosterone, thyroid function, insulin resistance, and Vitamin D interact as a single male weight-metabolic system by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations for weight, metabolism, and hormonal health\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePioneers of at-home \u003cstrong\u003edried blood spot (DBS)\u003c\/strong\u003e and saliva hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePersonalised reference ranges based on age and sex\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThrough our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to people across the UK and Europe — from the comfort of home.\u003c\/p\u003e\n\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhy does this test include Vitamin D?\u003c\/strong\u003e\u003cbr\u003eVitamin D deficiency independently impairs testosterone synthesis, worsens insulin resistance, elevates hsCRP, and slows thyroid T4-to-T3 conversion. It is one of the most prevalent deficiencies in the UK and directly compounds every hormonal and metabolic driver of weight gain in men — making it an essential component of a comprehensive weight management profile.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy test all five systems together rather than individually?\u003c\/strong\u003e\u003cbr\u003eCortisol, testosterone, thyroid, insulin, and Vitamin D form a single integrated metabolic network. Each drives the others: cortisol suppresses testosterone and thyroid; low testosterone worsens insulin resistance; thyroid insufficiency slows metabolism; insulin resistance drives visceral fat and aromatase. Testing all five together reveals the root-cause interaction pattern that single-system testing cannot identify.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan I use this test if I am on TRT or levothyroxine?\u003c\/strong\u003e\u003cbr\u003eYes. This test is particularly valuable for men on TRT or thyroid medication wanting to understand how their treatment is interacting with cortisol rhythm, insulin resistance, cardiometabolic markers, and Vitamin D status.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is fasting insulin and why does it matter for weight management?\u003c\/strong\u003e\u003cbr\u003eFasting insulin is the earliest detectable marker of insulin resistance — elevated years before HbA1c becomes abnormal. In men, elevated insulin promotes visceral fat, drives Estradiol (E2) conversion via aromatase, suppresses testosterone, and independently raises cardiovascular risk. It is the most actionable early metabolic marker in this profile.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. There are no additional charges. You are only responsible for posting your samples to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":57960340029821,"sku":"1500","price":620.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/SalivaandBloodSpotHormoneTestKit.webp?v=1785073903"},{"product_id":"male-comprehensive-hormone-thyroid-cardiometabolic-test","title":"Male Comprehensive Hormone, Thyroid \u0026 CardioMetabolic Test","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e SB-652 | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Saliva + Dried Blood Spot | \u003cstrong\u003eTechnology:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults Time:\u003c\/strong\u003e 3-5 Working Days After Laboratory Receives Sample | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory - CLIA Certified | \u003cstrong\u003eHormone Specialist Doctor Interpretation:\u003c\/strong\u003e Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\u003ch2\u003eWhat Does This Test Measure?\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eSaliva - Sex Hormones (LC-MS\/MS):\u003c\/strong\u003e Estradiol (E2), Estriol (E3), Estrone (E1), Progesterone, Testosterone, DHEAS.\u003cbr\u003e\u003cstrong\u003eSaliva - 4-Point Cortisol Profile:\u003c\/strong\u003e Morning, Noon, Evening, and Night Cortisol.\u003cbr\u003e\u003cstrong\u003eBlood Spot - Full Thyroid Panel:\u003c\/strong\u003e TSH, Free T3, Free T4, Total T4, TPO Antibodies, Thyroglobulin Antibodies.\u003cbr\u003e\u003cstrong\u003eBlood Spot - CardioMetabolic Panel:\u003c\/strong\u003e Fasting Insulin, HbA1c, HDL Cholesterol, Triglycerides, Total Cholesterol, hsCRP.\u003cbr\u003e22 markers total - the most comprehensive at-home male health profile available in the UK, covering androgenic balance, the full daily cortisol rhythm, autoimmune thyroid function, and cardiometabolic risk in a single kit.\u003c\/p\u003e\u003ch2\u003eRelated Symptoms\u003c\/h2\u003e\u003cp\u003ePersistent fatigue, unexplained weight gain, low libido, erectile dysfunction, poor exercise recovery, brain fog, low mood, feeling cold, dry skin, hair thinning, acne, gynaecomastia, sugar cravings, energy crashes, elevated cholesterol or triglycerides on previous testing, insomnia, chronic stress, burnout, or symptoms of low testosterone with normal standard blood results.\u003c\/p\u003e\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003ePersistent fatigue that does not improve with rest or sleep\u003c\/li\u003e\n\u003cli\u003eUnexplained weight gain, particularly around the abdomen\u003c\/li\u003e\n\u003cli\u003eLow libido, erectile dysfunction, or reduced sexual performance\u003c\/li\u003e\n\u003cli\u003ePoor recovery from exercise or sustained high workload\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor concentration, or low mood\u003c\/li\u003e\n\u003cli\u003eFeeling cold, dry skin, hair thinning, or slow metabolism\u003c\/li\u003e\n\u003cli\u003eAcne, scalp hair loss, or gynaecomastia\u003c\/li\u003e\n\u003cli\u003eSugar cravings, energy crashes, or afternoon slumps\u003c\/li\u003e\n\u003cli\u003eElevated cholesterol, triglycerides, or blood sugar on previous testing\u003c\/li\u003e\n\u003cli\u003eInsomnia, night waking, or unrefreshing sleep\u003c\/li\u003e\n\u003cli\u003eChronic stress or burnout\u003c\/li\u003e\n\u003cli\u003eSymptoms of low testosterone with normal or inconclusive standard blood results\u003c\/li\u003e\n\u003cli\u003eCurrently on TRT and wanting a comprehensive hormonal, thyroid, and metabolic picture\u003c\/li\u003e\n\u003cli\u003eDiagnosed or suspected Hashimoto's thyroiditis or autoimmune thyroid disease\u003c\/li\u003e\n\u003cli\u003eFamily history of thyroid disease, heart disease, diabetes, or metabolic syndrome\u003c\/li\u003e\n\u003cli\u003eMen over 35 seeking the single most comprehensive at-home androgenic and metabolic health assessment available\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eWhy This Test Is Particularly Important for Men\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eCortisol is the primary suppressor of testosterone and the primary driver of male cardiometabolic deterioration - through pregnenolone steal, Leydig cell suppression, visceral fat, aromatase-driven oestradiol excess, T3 conversion impairment, and insulin resistance, all simultaneously; the 4-point profile identifies which phase of the day is driving this cascade\u003c\/li\u003e\n\u003cli\u003eThyroid dysfunction is a major and systematically missed cause of low testosterone - hypothyroidism directly suppresses testosterone synthesis; cortisol-driven T3 suppression produces identical symptoms with a normal TSH; Hashimoto's is present years before TSH becomes abnormal\u003c\/li\u003e\n\u003cli\u003eThe 4-point cortisol profile is the essential lens for interpreting all other results - each time point (morning, noon, evening, night) has distinct androgenic, thyroid, and metabolic consequences that a single measurement cannot reveal\u003c\/li\u003e\n\u003cli\u003eInsulin resistance and testosterone decline are mutually reinforcing and thyroid-compounded - fasting insulin is the earliest detectable marker, elevated years before HbA1c becomes abnormal\u003c\/li\u003e\n\u003cli\u003ehsCRP is the convergence biomarker of the entire male hormonal-metabolic axis - elevated simultaneously by low testosterone, cortisol dysregulation, insulin resistance, oestradiol excess, and Hashimoto's autoimmunity\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\u003cp\u003eEmail us at \u003ca href=\"mailto:info@hormonelab.co.uk\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours.\u003c\/p\u003e\u003ch2\u003eHow It Works\u003c\/h2\u003e\u003col\u003e\n\u003cli\u003eOrder your kit - delivered directly to your door\u003c\/li\u003e\n\u003cli\u003eCollect saliva at four time points (morning before 9am, noon, evening, night) and blood spot via finger-prick\u003c\/li\u003e\n\u003cli\u003ePost your samples to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your full report by email within 3-5 working days\u003c\/li\u003e\n\u003c\/ol\u003e\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eAll 22 marker results with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eVisual charts for all sex hormones, your full 4-point cortisol daily curve, thyroid panel, and all six cardiometabolic markers\u003c\/li\u003e\n\u003cli\u003eIntegrated clinical interpretation of how testosterone, oestradiol, cortisol, thyroid markers, and cardiometabolic results interact as a single male hormonal-metabolic system by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003eCortisol-thyroid T3 interaction, Hashimoto's autoimmunity, and insulin resistance assessments\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included - no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e - a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003ePioneers of at-home \u003cstrong\u003edried blood spot (DBS)\u003c\/strong\u003e and saliva hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePersonalised reference ranges based on age and sex\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eThrough our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to people across the UK and Europe - from the comfort of home.\u003c\/p\u003e\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eWhy is this better than standard NHS blood tests?\u003c\/strong\u003e\u003cbr\u003eStandard NHS testing measures total testosterone by immunoassay, uses TSH as the sole thyroid marker, and does not assess cortisol rhythm, thyroid antibodies, fasting insulin, or hsCRP. This test measures free, bioavailable testosterone by LC-MS\/MS, provides the full 4-point cortisol rhythm, screens for Hashimoto's, and assesses insulin resistance and cardiovascular inflammation - revealing root causes that standard panels systematically miss.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCan I use this test if I am on TRT or levothyroxine?\u003c\/strong\u003e\u003cbr\u003eYes. This test is particularly valuable for men on TRT or thyroid medication wanting a complete picture of how their treatment is affecting their entire androgenic, thyroid, and cardiometabolic system.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eIs this suitable for men with Hashimoto's or suspected thyroid disease?\u003c\/strong\u003e\u003cbr\u003eYes - this is the most comprehensive thyroid assessment available in an at-home test for men, with both TPO and Tg antibodies alongside the full thyroid panel, 4-point cortisol, and insulin markers that directly drive autoimmune thyroid activity.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. There are no additional charges. You are only responsible for posting your samples to the laboratory.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":57960745206141,"sku":"2027","price":350.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/SalivaandBloodSpotHormoneTestKit.webp?v=1785073903"},{"product_id":"male-hormone-cardiometabolic-test","title":"Male Hormone \u0026 CardioMetabolic Test","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e SB-651 | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Saliva + Dried Blood Spot | \u003cstrong\u003eTechnology:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults Time:\u003c\/strong\u003e 3–5 Working Days After Laboratory Receives Sample | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eHormone Specialist Doctor Interpretation:\u003c\/strong\u003e Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children\u003c\/p\u003e\n\u003ch2\u003eWhat Does This Test Measure?\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSaliva — Sex Hormones (LC-MS\/MS):\u003c\/strong\u003e Estradiol (E2), Estriol (E3), Estrone (E1), Progesterone, Testosterone, DHEAS.\u003cbr\u003e\u003cstrong\u003eSaliva — 4-Point Cortisol Profile:\u003c\/strong\u003e Morning, Noon, Evening, and Night Cortisol.\u003cbr\u003e\u003cstrong\u003eBlood Spot — CardioMetabolic Panel:\u003c\/strong\u003e Fasting Insulin, HbA1c, HDL Cholesterol, Triglycerides, Total Cholesterol, hsCRP.\u003cbr\u003e16 markers total — a complete picture of male sex hormones, the full daily cortisol rhythm, and cardiometabolic risk in a single at-home kit.\u003c\/p\u003e\n\u003ch2\u003eRelated Symptoms\u003c\/h2\u003e\n\u003cp\u003ePersistent fatigue, unexplained abdominal weight gain, sugar cravings, energy crashes, elevated cholesterol or triglycerides on previous testing, low libido, erectile dysfunction, poor exercise recovery, brain fog, low mood, insomnia, chronic stress, burnout, or symptoms of low testosterone with normal standard blood results.\u003c\/p\u003e\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003ePersistent fatigue that does not improve with rest or sleep\u003c\/li\u003e\n\u003cli\u003eUnexplained weight gain, particularly around the abdomen\u003c\/li\u003e\n\u003cli\u003eSugar cravings, energy crashes, or afternoon slumps\u003c\/li\u003e\n\u003cli\u003eElevated cholesterol, triglycerides, or blood sugar on previous testing\u003c\/li\u003e\n\u003cli\u003eLow libido, erectile dysfunction, or reduced sexual performance\u003c\/li\u003e\n\u003cli\u003ePoor recovery from exercise or sustained high-pressure workload\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor concentration, or low mood\u003c\/li\u003e\n\u003cli\u003eInsomnia, night waking, or unrefreshing sleep\u003c\/li\u003e\n\u003cli\u003eChronic stress or burnout\u003c\/li\u003e\n\u003cli\u003eSymptoms of low testosterone with normal or inconclusive standard blood results\u003c\/li\u003e\n\u003cli\u003eCurrently on TRT and wanting a complete metabolic and hormonal picture\u003c\/li\u003e\n\u003cli\u003eFamily history of heart disease, diabetes, or metabolic syndrome\u003c\/li\u003e\n\u003cli\u003eMen over 35 seeking a comprehensive androgenic and cardiometabolic health baseline\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy This Test Is Particularly Important for Men\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eLow testosterone is a primary and independent cardiometabolic risk factor — it independently raises triglycerides, suppresses HDL, promotes visceral fat, and elevates hsCRP and the risk of metabolic syndrome and type 2 diabetes\u003c\/li\u003e\n\u003cli\u003eThe 4-point cortisol profile reveals the complete daily adrenal rhythm — each time point (morning, noon, evening, night) has distinct hormonal and metabolic consequences; a single cortisol measurement cannot identify which phase is driving androgenic or cardiometabolic deterioration\u003c\/li\u003e\n\u003cli\u003eInsulin resistance and testosterone decline are mutually reinforcing — fasting insulin is the earliest detectable marker, elevated years before HbA1c becomes abnormal, and directly linked to erectile dysfunction and hormonal decline\u003c\/li\u003e\n\u003cli\u003eOestradiol excess compounds every cardiometabolic risk factor — excess oestradiol from visceral fat suppresses testosterone, raises triglycerides, and drives hsCRP elevation\u003c\/li\u003e\n\u003cli\u003ehsCRP is the convergence biomarker of the entire male hormonal-metabolic axis — a stronger independent predictor of cardiovascular events than LDL cholesterol\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca href=\"mailto:info@hormonelab.co.uk\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours.\u003c\/p\u003e\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered directly to your door\u003c\/li\u003e\n\u003cli\u003eCollect saliva at four time points (morning before 9am, noon, evening, night) and blood spot via finger-prick\u003c\/li\u003e\n\u003cli\u003ePost your samples to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your full report by email within 3–5 working days\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll 16 marker results with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eVisual charts for all sex hormones, your full 4-point cortisol daily curve, and all six cardiometabolic markers\u003c\/li\u003e\n\u003cli\u003eIntegrated clinical interpretation connecting cortisol, testosterone, oestradiol, insulin resistance, and cardiovascular risk by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePioneers of at-home \u003cstrong\u003edried blood spot (DBS)\u003c\/strong\u003e and saliva hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePersonalised reference ranges based on age and sex\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThrough our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to people across the UK and Europe — from the comfort of home.\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhy test hormones and cardiometabolic markers together?\u003c\/strong\u003e\u003cbr\u003eIn men, testosterone, cortisol, and insulin form a single integrated metabolic system. Testing both together reveals whether metabolic symptoms are driven by hormonal root causes — something single-system testing cannot achieve.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is a 4-point cortisol more informative than a single measurement?\u003c\/strong\u003e\u003cbr\u003eEach time point has different hormonal and metabolic consequences. Morning cortisol sets insulin sensitivity and testosterone output for the day; elevated noon cortisol drives visceral fat and oestradiol conversion; elevated night cortisol suppresses testosterone production during sleep.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan I use this test if I am on TRT?\u003c\/strong\u003e\u003cbr\u003eYes. This test is particularly valuable for men on TRT wanting to monitor oestradiol balance, insulin sensitivity, triglycerides, and inflammation alongside testosterone.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. There are no additional charges. You are only responsible for posting your samples to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":57961143304573,"sku":"20260","price":309.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/SalivaandBloodSpotHormoneTestKit.webp?v=1785073903"},{"product_id":"male-advanced-hormone-stress-thyroid-test","title":"Male Advanced Hormone, Stress \u0026 Thyroid Test","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e SB-650 | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Saliva + Dried Blood Spot | \u003cstrong\u003eTechnology:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults Time:\u003c\/strong\u003e 3–5 Working Days After Laboratory Receives Sample | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eHormone Specialist Doctor Interpretation:\u003c\/strong\u003e Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\n\u003ch2\u003eWhat Does This Test Measure?\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSaliva — Sex Hormones (LC-MS\/MS):\u003c\/strong\u003e Estradiol (E2), Estriol (E3), Estrone (E1), Progesterone, Testosterone, DHEAS.\u003cbr\u003e\n\u003cstrong\u003eSaliva — 4-Point Cortisol Profile:\u003c\/strong\u003e Morning, Noon, Evening, and Night Cortisol.\u003cbr\u003e\n\u003cstrong\u003eBlood Spot — Full Thyroid Panel:\u003c\/strong\u003e TSH, Free T3, Free T4, Total T4, TPO Antibodies, Thyroglobulin Antibodies.\u003cbr\u003e\n16 markers total — a complete picture of androgenic balance, the full daily cortisol rhythm, and autoimmune thyroid function in a single at-home kit.\u003c\/p\u003e\n\n\u003ch2\u003eRelated Symptoms\u003c\/h2\u003e\n\u003cp\u003ePersistent fatigue, low libido, erectile dysfunction, unexplained weight gain, poor exercise recovery, brain fog, low mood, feeling cold, dry skin, hair thinning, acne, gynaecomastia, insomnia, chronic stress, burnout, or symptoms of low testosterone with normal standard blood results.\u003c\/p\u003e\n\n\u003ch2\u003eDid You Know?\u003c\/h2\u003e\n\u003cp\u003eCortisol-driven T3 suppression produces identical symptoms to hypothyroidism — fatigue, weight gain, cold intolerance, brain fog, low libido — with a completely normal TSH. This pattern is only detectable when Free T3 is measured alongside the 4-point cortisol rhythm. Hashimoto’s autoimmunity (TPO and Tg antibodies) is frequently present in men years before TSH becomes abnormal — making antibody testing essential for early detection of the most common cause of thyroid dysfunction in men under 50.\u003c\/p\u003e\n\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003ePersistent fatigue that does not improve with rest or sleep\u003c\/li\u003e\n\u003cli\u003eLow libido, erectile dysfunction, or reduced sexual performance\u003c\/li\u003e\n\u003cli\u003eUnexplained weight gain, particularly around the abdomen\u003c\/li\u003e\n\u003cli\u003ePoor recovery from exercise or sustained high workload\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor concentration, or low mood\u003c\/li\u003e\n\u003cli\u003eFeeling cold, dry skin, or hair thinning\u003c\/li\u003e\n\u003cli\u003eAcne, oily skin, or gynaecomastia\u003c\/li\u003e\n\u003cli\u003eInsomnia, night waking, or unrefreshing sleep\u003c\/li\u003e\n\u003cli\u003eChronic stress or burnout\u003c\/li\u003e\n\u003cli\u003eSymptoms of low testosterone with normal or inconclusive standard blood results\u003c\/li\u003e\n\u003cli\u003eCurrently on TRT and wanting comprehensive hormonal and thyroid monitoring\u003c\/li\u003e\n\u003cli\u003eDiagnosed or suspected Hashimoto’s thyroiditis or autoimmune thyroid disease\u003c\/li\u003e\n\u003cli\u003eFamily history of thyroid disease, cardiovascular disease, or metabolic syndrome\u003c\/li\u003e\n\u003cli\u003eMen over 35 seeking a comprehensive androgenic and thyroid health assessment\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy This Test Is Particularly Important for Men\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eCortisol is the primary suppressor of testosterone — through pregnenolone steal and direct Leydig cell suppression, chronic cortisol elevation drives compounding hormonal deficit that TSH and total testosterone blood tests cannot detect\u003c\/li\u003e\n\u003cli\u003eThyroid dysfunction is a major and overlooked cause of low testosterone — hypothyroidism directly suppresses Leydig cell function; cortisol-driven T3 suppression produces identical symptoms with a normal TSH\u003c\/li\u003e\n\u003cli\u003eSaliva LC-MS\/MS measures free, bioavailable testosterone — a man with elevated SHBG from ageing or thyroid dysfunction can have normal total testosterone but critically low free testosterone\u003c\/li\u003e\n\u003cli\u003eAll three estrogens reveal the full estrogenic load — excess estradiol from visceral fat and cortisol suppresses testosterone and drives cardiovascular risk; Estrone (E1) and Estriol (E3) provide aromatase activity context that Estradiol (E2) alone cannot\u003c\/li\u003e\n\u003cli\u003eTPO and Tg antibodies detect autoimmune thyroid disease years before TSH becomes abnormal — both markers are required as some men have elevated Tg antibodies with normal TPO\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca href=\"mailto:info@hormonelab.co.uk\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours.\u003c\/p\u003e\n\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered directly to your door\u003c\/li\u003e\n\u003cli\u003eCollect saliva at four time points (morning before 9am, noon, evening, night) and blood spot via finger-prick\u003c\/li\u003e\n\u003cli\u003ePost your samples to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your full report by email within 3–5 working days\u003c\/li\u003e\n\u003c\/ol\u003e\n\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll 16 marker results with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eVisual charts for all six sex hormones, your full 4-point cortisol curve, and thyroid panel values\u003c\/li\u003e\n\u003cli\u003eIntegrated clinical interpretation of how testosterone, estradiol, progesterone, DHEAS, cortisol, and thyroid markers interact by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003eCortisol-thyroid interaction assessment — including whether cortisol is impairing T3 conversion and suppressing Leydig cell function\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePioneers of at-home \u003cstrong\u003edried blood spot (DBS)\u003c\/strong\u003e and saliva hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePersonalised reference ranges based on age and sex\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThrough our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to people across the UK and Europe — from the comfort of home.\u003c\/p\u003e\n\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is LC-MS\/MS used for sex hormones?\u003c\/strong\u003e\u003cbr\u003eLC-MS\/MS measures free, bioavailable hormones — the fraction actually reaching cells and driving androgenic function. A man with high SHBG can have normal total testosterone but critically low free testosterone. LC-MS\/MS reveals the true androgenic picture that standard blood tests miss.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy do men need estrogen tested?\u003c\/strong\u003e\u003cbr\u003eMen produce estradiol through aromatase conversion of testosterone. Excess estradiol suppresses testosterone, causes gynaecomastia, and drives fat accumulation. Measuring all three estrogens — Estradiol (E2), Estriol (E3), and Estrone (E1) — reveals the full estrogenic load and aromatase activity driving hormonal imbalance.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan I use this test if I am on TRT or levothyroxine?\u003c\/strong\u003e\u003cbr\u003eYes. This test is particularly valuable for men on TRT wanting to monitor estradiol balance, cortisol pattern, and thyroid function alongside testosterone.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy measure cortisol at four time points?\u003c\/strong\u003e\u003cbr\u003eEach time point has different hormonal and metabolic consequences. A single cortisol value cannot distinguish between adrenal burnout, high morning reactivity, evening elevation, or night excess — each requiring a different intervention.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. There are no additional charges. You are only responsible for posting your samples to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":57961191244157,"sku":"1022","price":266.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/SalivaandBloodSpotHormoneTestKit.webp?v=1785073903"},{"product_id":"male-advanced-hormone-thyroid-cardiometabolic-test","title":"Male Advanced Hormone, Thyroid \u0026 CardioMetabolic Test","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e SB-649 | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Saliva + Dried Blood Spot | \u003cstrong\u003eTechnology:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults Time:\u003c\/strong\u003e 3–5 Working Days After Laboratory Receives Sample | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eHormone Specialist Doctor Interpretation:\u003c\/strong\u003e Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\u003ch2\u003eWhat Does This Test Measure?\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSaliva — Sex Hormones \u0026amp; Cortisol (LC-MS\/MS):\u003c\/strong\u003e Estradiol (E2), Estriol (E3), Estrone (E1), Progesterone, Testosterone, DHEAS, Cortisol.\u003cbr\u003e\u003cstrong\u003eBlood Spot — Full Thyroid Panel:\u003c\/strong\u003e TSH, Free T3, Free T4, Total T4, TPO Antibodies, Thyroglobulin Antibodies.\u003cbr\u003e\u003cstrong\u003eBlood Spot — CardioMetabolic Panel:\u003c\/strong\u003e Fasting Insulin, HbA1c, HDL Cholesterol, Triglycerides, Total Cholesterol, hsCRP.\u003cbr\u003e19 markers total — a complete picture of androgenic balance, thyroid function including autoimmune markers, and cardiometabolic risk in a single at-home kit.\u003c\/p\u003e\n\u003ch2\u003eRelated Symptoms\u003c\/h2\u003e\n\u003cp\u003ePersistent fatigue, unexplained weight gain, low libido, erectile dysfunction, poor exercise recovery, brain fog, low mood, feeling cold, dry skin, hair thinning, sugar cravings, energy crashes, elevated cholesterol or triglycerides on previous testing, insomnia, chronic stress, burnout, or symptoms of low testosterone with normal standard blood results.\u003c\/p\u003e\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003ePersistent fatigue that does not improve with rest or sleep\u003c\/li\u003e\n\u003cli\u003eUnexplained weight gain, particularly around the abdomen\u003c\/li\u003e\n\u003cli\u003eLow libido, erectile dysfunction, or reduced sexual performance\u003c\/li\u003e\n\u003cli\u003ePoor recovery from exercise or sustained high workload\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor concentration, or low mood\u003c\/li\u003e\n\u003cli\u003eFeeling cold, dry skin, or hair thinning\u003c\/li\u003e\n\u003cli\u003eSugar cravings, energy crashes, or afternoon slumps\u003c\/li\u003e\n\u003cli\u003eElevated cholesterol, triglycerides, or blood sugar on previous testing\u003c\/li\u003e\n\u003cli\u003eInsomnia, night waking, or unrefreshing sleep\u003c\/li\u003e\n\u003cli\u003eChronic stress or burnout\u003c\/li\u003e\n\u003cli\u003eSymptoms of low testosterone with normal or inconclusive standard blood results\u003c\/li\u003e\n\u003cli\u003eCurrently on TRT and wanting to monitor thyroid, oestradiol, and metabolic markers alongside testosterone\u003c\/li\u003e\n\u003cli\u003eDiagnosed or suspected Hashimoto’s thyroiditis or autoimmune thyroid disease\u003c\/li\u003e\n\u003cli\u003eFamily history of thyroid disease, heart disease, diabetes, or metabolic syndrome\u003c\/li\u003e\n\u003cli\u003eMen over 35 wanting a comprehensive androgenic, thyroid, and cardiometabolic health baseline\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy This Test Is Particularly Important for Men\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eCortisol is the central disruptor of all three systems simultaneously — depleting testosterone via pregnenolone steal, impairing thyroid T4-to-T3 conversion, and driving insulin resistance, visceral fat, triglyceride elevation, and hsCRP all at once\u003c\/li\u003e\n\u003cli\u003eThyroid dysfunction is a major and overlooked cause of low testosterone — hypothyroidism directly suppresses Leydig cell function; cortisol-driven T3 suppression produces identical symptoms with a normal TSH\u003c\/li\u003e\n\u003cli\u003eTSH alone misses three critical patterns — cortisol-driven T3 suppression, early thyroid insufficiency, and Hashimoto’s autoimmunity; both TPO and Tg antibodies are required as some men have elevated Tg with normal TPO\u003c\/li\u003e\n\u003cli\u003eInsulin resistance and testosterone decline are mutually reinforcing and thyroid-compounded — fasting insulin is the earliest detectable marker, elevated years before HbA1c becomes abnormal\u003c\/li\u003e\n\u003cli\u003ehsCRP is the convergence biomarker of all three systems — elevated simultaneously by low testosterone, cortisol dysregulation, insulin resistance, oestradiol excess, and Hashimoto’s autoimmunity\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca href=\"mailto:info@hormonelab.co.uk\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours.\u003c\/p\u003e\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered directly to your door\u003c\/li\u003e\n\u003cli\u003eCollect your saliva sample (morning before 9am for optimal cortisol accuracy) and blood spot via finger-prick\u003c\/li\u003e\n\u003cli\u003ePost your samples to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your full report by email within 3–5 working days\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll 19 marker results with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eVisual charts for all sex hormones, cortisol, the full thyroid panel, and all six cardiometabolic markers\u003c\/li\u003e\n\u003cli\u003eIntegrated clinical interpretation of how testosterone, oestradiol, cortisol, thyroid markers, and cardiometabolic results interact by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003eCortisol-thyroid T3 interaction and Hashimoto’s assessment in insulin and cortisol context\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePioneers of at-home \u003cstrong\u003edried blood spot (DBS)\u003c\/strong\u003e and saliva hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePersonalised reference ranges based on age and sex\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThrough our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to people across the UK and Europe — from the comfort of home.\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is TSH alone not enough to assess thyroid health in men?\u003c\/strong\u003e\u003cbr\u003eTSH measures the pituitary signal to the thyroid, not the active hormone reaching cells. Cortisol-driven T3 suppression produces functional hypothyroidism with a normal TSH. Hashimoto’s causes progressive thyroid damage for years before TSH becomes abnormal. Both patterns are invisible to TSH alone.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan I use this test if I am on TRT or levothyroxine?\u003c\/strong\u003e\u003cbr\u003eYes. This test is particularly valuable for men on TRT wanting to monitor thyroid markers, oestradiol balance, insulin sensitivity, and inflammation alongside testosterone.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIs this test suitable for men with Hashimoto’s or suspected thyroid disease?\u003c\/strong\u003e\u003cbr\u003eYes — the full 6-marker thyroid panel includes both TPO and Tg antibodies for complete Hashimoto’s screening alongside the cortisol and insulin markers that drive autoimmune thyroid activity.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. There are no additional charges. You are only responsible for posting your samples to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":57961246818685,"sku":"1016","price":323.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/SalivaandBloodSpotHormoneTestKit.webp?v=1785073903"},{"product_id":"male-comprehensive-hormone-cardiometabolic-test","title":"Male Comprehensive Hormone \u0026 CardioMetabolic Test","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e SB-648 | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Saliva + Dried Blood Spot | \u003cstrong\u003eTechnology:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults Time:\u003c\/strong\u003e 3–5 Working Days After Laboratory Receives Sample | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eHormone Specialist Doctor Interpretation:\u003c\/strong\u003e Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children\u003c\/p\u003e\n\n\u003ch2\u003eWhat Does This Test Measure?\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSaliva — Sex Hormones \u0026amp; Cortisol (LC-MS\/MS):\u003c\/strong\u003e Estradiol (E2), Estriol (E3), Estrone (E1), Progesterone, Testosterone, DHEAS, Cortisol.\u003cbr\u003e\n\u003cstrong\u003eBlood Spot — CardioMetabolic Panel:\u003c\/strong\u003e Fasting Insulin, HbA1c, HDL Cholesterol, Triglycerides, Total Cholesterol, hsCRP.\u003cbr\u003e\n13 markers total — an integrated assessment of male sex hormones, stress hormones, and cardiometabolic risk in a single at-home kit.\u003c\/p\u003e\n\n\u003ch2\u003eRelated Symptoms\u003c\/h2\u003e\n\u003cp\u003ePersistent fatigue, unexplained abdominal weight gain, low libido, erectile dysfunction, poor exercise recovery, brain fog, low mood, sugar cravings, energy crashes, elevated cholesterol or triglycerides on previous testing, insomnia, chronic stress, burnout, or symptoms of low testosterone with normal standard blood results.\u003c\/p\u003e\n\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003ePersistent fatigue that does not improve with rest or sleep\u003c\/li\u003e\n\u003cli\u003eUnexplained weight gain, particularly around the abdomen\u003c\/li\u003e\n\u003cli\u003eLow libido, erectile dysfunction, or reduced sexual performance\u003c\/li\u003e\n\u003cli\u003ePoor recovery from exercise or sustained high-pressure workload\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor concentration, or low mood\u003c\/li\u003e\n\u003cli\u003eSugar cravings, energy crashes, or afternoon slumps\u003c\/li\u003e\n\u003cli\u003eElevated cholesterol, triglycerides, or blood sugar on previous testing\u003c\/li\u003e\n\u003cli\u003eInsomnia, night waking, or unrefreshing sleep\u003c\/li\u003e\n\u003cli\u003eChronic stress or burnout\u003c\/li\u003e\n\u003cli\u003eSymptoms of low testosterone with normal or inconclusive standard blood results\u003c\/li\u003e\n\u003cli\u003eCurrently on TRT and wanting to monitor estradiol, insulin, and inflammation alongside testosterone\u003c\/li\u003e\n\u003cli\u003eFamily history of heart disease, diabetes, or metabolic syndrome\u003c\/li\u003e\n\u003cli\u003eMen over 35 seeking a comprehensive androgenic and cardiometabolic health baseline\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy This Test Is Particularly Important for Men\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eLow testosterone is a primary and independent cardiometabolic risk factor — it independently raises triglycerides, suppresses HDL, promotes visceral fat, elevates hsCRP, and increases the risk of metabolic syndrome and type 2 diabetes\u003c\/li\u003e\n\u003cli\u003eCortisol is the central disruptor of testosterone and every cardiometabolic marker simultaneously — measuring it via saliva LC-MS\/MS alongside the cardiometabolic markers reveals the hormonal root cause of metabolic deterioration\u003c\/li\u003e\n\u003cli\u003eInsulin resistance and testosterone decline are mutually reinforcing — elevated insulin promotes aromatase-driven estrogen conversion, suppressing testosterone; low testosterone worsens insulin sensitivity; fasting insulin is the earliest detectable marker, elevated years before HbA1c becomes abnormal\u003c\/li\u003e\n\u003cli\u003eEstradiol imbalance compounds every cardiometabolic risk factor — excess estradiol from visceral fat suppresses testosterone, raises triglycerides, and drives hsCRP elevation\u003c\/li\u003e\n\u003cli\u003ehsCRP is the convergence biomarker of the entire male hormonal-metabolic axis — elevated simultaneously by low testosterone, cortisol dysregulation, insulin resistance, visceral fat, and estradiol excess\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca href=\"mailto:info@hormonelab.co.uk\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours.\u003c\/p\u003e\n\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered directly to your door\u003c\/li\u003e\n\u003cli\u003eCollect your saliva sample (morning before 9am for optimal cortisol accuracy) and blood spot via finger-prick\u003c\/li\u003e\n\u003cli\u003ePost your samples to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your full report by email within 3–5 working days\u003c\/li\u003e\n\u003c\/ol\u003e\n\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll 13 marker results with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eVisual charts for all sex hormones, cortisol, and all six cardiometabolic markers\u003c\/li\u003e\n\u003cli\u003eIntegrated clinical interpretation connecting cortisol, testosterone, estradiol, and cardiometabolic risk by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePioneers of at-home \u003cstrong\u003edried blood spot (DBS)\u003c\/strong\u003e and saliva hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePersonalised reference ranges based on age and sex\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThrough our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to people across the UK and Europe — from the comfort of home.\u003c\/p\u003e\n\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhy test hormones and cardiometabolic markers together?\u003c\/strong\u003e\u003cbr\u003eIn men, testosterone, cortisol, and insulin form a single integrated metabolic system. Low testosterone independently raises cardiovascular risk and worsens insulin resistance. Cortisol simultaneously suppresses testosterone and drives every cardiometabolic risk marker. Testing both together reveals hormonal root causes of metabolic symptoms that single-system testing cannot achieve.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is saliva LC-MS\/MS used for sex hormones and cortisol?\u003c\/strong\u003e\u003cbr\u003eSaliva LC-MS\/MS measures free, bioavailable hormones — the fraction actually reaching cells and driving androgenic and metabolic function. A man with high SHBG can have normal total testosterone but critically low free testosterone with full androgenic deficiency symptoms. Saliva LC-MS\/MS captures this clinically important distinction.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan I use this test if I am on TRT?\u003c\/strong\u003e\u003cbr\u003eYes. This test is particularly valuable for men on TRT wanting to monitor estradiol balance, insulin sensitivity, triglycerides, and inflammation alongside testosterone.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. There are no additional charges. You are only responsible for posting your samples to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":57961292202365,"sku":"1019","price":283.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/SalivaandBloodSpotHormoneTestKit.webp?v=1785073903"},{"product_id":"male-hormone-thyroid-test-kit","title":"Male Hormone \u0026 Thyroid Test Kit","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e SB-647M | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Saliva + Dried Blood Spot | \u003cstrong\u003eTechnology:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults Time:\u003c\/strong\u003e 3–5 Working Days After Laboratory Receives Sample | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eHormone Specialist Doctor Interpretation:\u003c\/strong\u003e Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\n\u003ch2\u003eWhat Does This Test Measure?\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSaliva — Sex \u0026amp; Stress Hormones (LC-MS\/MS):\u003c\/strong\u003e Estradiol (E2), Estriol (E3), Estrone (E1), Progesterone, Testosterone, DHEAS, Cortisol (4-point: morning, noon, evening, night).\u003cbr\u003e\u003cstrong\u003eBlood Spot — Full Thyroid Panel:\u003c\/strong\u003e TSH, Free T3, Free T4, Total T4, TPO Antibodies, Thyroglobulin Antibodies.\u003cbr\u003e13 markers total — a clinically complete picture of androgenic balance, adrenal stress load, oestrogen metabolism, and thyroid function in a single at-home kit.\u003c\/p\u003e\n\n\u003ch2\u003eRelated Symptoms\u003c\/h2\u003e\n\u003cp\u003ePersistent fatigue, low libido, erectile dysfunction, unexplained abdominal weight gain, poor exercise recovery, brain fog, low mood, feeling cold, dry skin, hair thinning, acne, gynaecomastia, insomnia, chronic stress, burnout, or symptoms of low testosterone with normal standard blood results.\u003c\/p\u003e\n\n\u003ch2\u003eDid You Know?\u003c\/h2\u003e\n\u003cp\u003eHypothyroidism suppresses Leydig cell testosterone production and compounds every symptom of low testosterone. Cortisol-driven T3 suppression produces identical symptoms with a completely normal TSH. And excess oestradiol from aromatase conversion can suppress testosterone and libido while total testosterone appears normal. This test assesses the entire interconnected system — something standard panels do not do.\u003c\/p\u003e\n\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003ePersistent fatigue or exhaustion that does not improve with rest or sleep\u003c\/li\u003e\n\u003cli\u003eLow libido or reduced sexual interest\u003c\/li\u003e\n\u003cli\u003eErectile dysfunction or reduced sexual performance\u003c\/li\u003e\n\u003cli\u003eUnexplained weight gain, particularly around the abdomen\u003c\/li\u003e\n\u003cli\u003ePoor recovery from exercise or sustained high workload\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor concentration, or low mood\u003c\/li\u003e\n\u003cli\u003eFeeling cold, dry skin, or hair thinning\u003c\/li\u003e\n\u003cli\u003eAcne or gynaecomastia alongside other hormonal symptoms\u003c\/li\u003e\n\u003cli\u003eInsomnia, night waking, or unrefreshing sleep\u003c\/li\u003e\n\u003cli\u003eChronic stress or burnout\u003c\/li\u003e\n\u003cli\u003eSymptoms of low testosterone with normal or inconclusive standard blood results\u003c\/li\u003e\n\u003cli\u003eCurrently on TRT or levothyroxine and wanting comprehensive hormonal monitoring\u003c\/li\u003e\n\u003cli\u003eMen over 35 seeking a complete androgenic, thyroid, and adrenal health baseline\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy This Test Is Particularly Important for Men\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eHypothyroidism suppresses Leydig cell testosterone production — compounding every symptom of low testosterone while thyroid disease goes undetected on a TSH-only test\u003c\/li\u003e\n\u003cli\u003eCortisol-driven T3 suppression produces hypothyroid symptoms with a completely normal TSH — only detectable when Free T3 is measured alongside the 4-point cortisol rhythm\u003c\/li\u003e\n\u003cli\u003eExcess oestradiol from aromatase conversion suppresses testosterone via the HPG axis — causing symptoms of androgen deficiency with normal total testosterone values\u003c\/li\u003e\n\u003cli\u003eThe 4-point cortisol rhythm reveals which phase of the day is driving androgenic and thyroid suppression — something a single cortisol measurement cannot identify\u003c\/li\u003e\n\u003cli\u003eTPO and Tg antibodies detect autoimmune thyroid disease years before TSH becomes abnormal — the most common cause of thyroid dysfunction in men under 50\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca href=\"mailto:info@hormonelab.co.uk\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours.\u003c\/p\u003e\n\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered directly to your door\u003c\/li\u003e\n\u003cli\u003eCollect saliva at four time points (morning before 9am, noon, evening, night) and blood spot via finger-prick\u003c\/li\u003e\n\u003cli\u003ePost your samples to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your full report by email within 3–5 working days\u003c\/li\u003e\n\u003c\/ol\u003e\n\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll 13 marker results with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eVisual charts for all seven saliva hormones, your full cortisol curve, and thyroid panel values\u003c\/li\u003e\n\u003cli\u003eWritten interpretation by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePioneers of at-home \u003cstrong\u003edried blood spot (DBS)\u003c\/strong\u003e and saliva hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePersonalised reference ranges based on age and sex\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThrough our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to people across the UK and Europe — from the comfort of home.\u003c\/p\u003e\n\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhy do men need oestrogen tested?\u003c\/strong\u003e\u003cbr\u003eMen produce oestradiol through aromatase conversion of testosterone. Excess oestradiol suppresses testosterone, causes gynaecomastia, and drives fat accumulation. Measuring all three oestrogens alongside testosterone reveals whether the androgen-oestrogen ratio is clinically balanced.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy saliva instead of blood for sex hormones?\u003c\/strong\u003e\u003cbr\u003eSaliva measures bioavailable (free, active) hormones — the fraction actually reaching your cells. Blood tests measure total hormone including the bound, inactive fraction, which can mask imbalances most relevant to symptoms.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan I use this test if I am on TRT or levothyroxine?\u003c\/strong\u003e\u003cbr\u003eYes. This test is particularly valuable for men on TRT wanting to understand their oestradiol balance, cortisol pattern, and thyroid function alongside testosterone.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy measure cortisol at four time points?\u003c\/strong\u003e\u003cbr\u003eA single cortisol measurement cannot distinguish between adrenal burnout, high morning reactivity, evening elevation, or night excess — each with different effects on testosterone and thyroid function. The 4-point profile captures the full daily adrenal rhythm.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. There are no additional charges. You are only responsible for posting your samples to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":57961331622269,"sku":"1018","price":240.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/SalivaandBloodSpotHormoneTestKit.webp?v=1785073903"},{"product_id":"male-comprehensive-hormone-thyroid-cardiometabolic-profile","title":"Male Comprehensive Hormone, Thyroid \u0026 CardioMetabolic Profile","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e SB-646M | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Saliva + Dried Blood Spot | \u003cstrong\u003eTechnology:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults Time:\u003c\/strong\u003e 3-5 Working Days After Laboratory Receives Sample | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory - CLIA Certified | \u003cstrong\u003eHormone Specialist Doctor Interpretation:\u003c\/strong\u003e Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\u003ch2\u003eWhat Does This Test Measure?\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eSaliva - 4-Point Cortisol Profile:\u003c\/strong\u003e Morning, Noon, Evening, and Night Cortisol.\u003cbr\u003e\u003cstrong\u003eBlood Spot - Sex Hormones + SHBG (LC-MS\/MS):\u003c\/strong\u003e Estradiol (E2), Estriol (E3), Estrone (E1), Progesterone, Testosterone, DHEAS, Cortisol, SHBG.\u003cbr\u003e\u003cstrong\u003eBlood Spot - Full Thyroid Panel:\u003c\/strong\u003e TSH, Free T3, Free T4, Total T4, TPO Antibodies, Thyroglobulin Antibodies.\u003cbr\u003e\u003cstrong\u003eBlood Spot - CardioMetabolic Panel:\u003c\/strong\u003e Fasting Insulin, HbA1c, HDL Cholesterol, Triglycerides, Total Cholesterol, hsCRP.\u003cbr\u003e24 markers total - the most comprehensive at-home male health profile available in the UK, covering the full daily cortisol rhythm, androgenic balance including SHBG, autoimmune thyroid function, and cardiometabolic risk in a single kit.\u003c\/p\u003e\u003ch2\u003eRelated Symptoms\u003c\/h2\u003e\u003cp\u003ePersistent fatigue, unexplained weight gain, low libido, erectile dysfunction, poor exercise recovery, brain fog, low mood, feeling cold, dry skin, hair thinning, sugar cravings, energy crashes, elevated cholesterol or triglycerides on previous testing, insomnia, chronic stress, burnout, symptoms of low testosterone with normal standard blood results, or told testosterone is normal but symptoms persist.\u003c\/p\u003e\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003ePersistent fatigue that does not improve with rest or sleep\u003c\/li\u003e\n\u003cli\u003eUnexplained weight gain, particularly around the abdomen\u003c\/li\u003e\n\u003cli\u003eLow libido, erectile dysfunction, or reduced sexual performance\u003c\/li\u003e\n\u003cli\u003ePoor recovery from exercise or sustained high workload\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor concentration, or low mood\u003c\/li\u003e\n\u003cli\u003eFeeling cold, dry skin, hair thinning, or slow metabolism\u003c\/li\u003e\n\u003cli\u003eSugar cravings, energy crashes, or afternoon slumps\u003c\/li\u003e\n\u003cli\u003eElevated cholesterol, triglycerides, or blood sugar on previous testing\u003c\/li\u003e\n\u003cli\u003eInsomnia, night waking, or unrefreshing sleep\u003c\/li\u003e\n\u003cli\u003eChronic stress or burnout\u003c\/li\u003e\n\u003cli\u003eTold testosterone is normal but symptoms of androgen deficiency persist (elevated SHBG is frequently the explanation)\u003c\/li\u003e\n\u003cli\u003eCurrently on TRT and wanting to monitor SHBG, thyroid, estradiol, and metabolic markers alongside testosterone\u003c\/li\u003e\n\u003cli\u003eDiagnosed or suspected Hashimoto's thyroiditis or autoimmune thyroid disease\u003c\/li\u003e\n\u003cli\u003eOn levothyroxine and wanting complete thyroid monitoring alongside SHBG and sex hormone levels\u003c\/li\u003e\n\u003cli\u003eFamily history of thyroid disease, heart disease, diabetes, or metabolic syndrome\u003c\/li\u003e\n\u003cli\u003eMen over 35 seeking the single most comprehensive at-home androgenic, thyroid, and cardiometabolic health assessment available\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eWhy This Test Is Particularly Important for Men\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eThe 4-point cortisol rhythm is the master regulator of testosterone, SHBG, thyroid function, and metabolic health - each time point has distinct androgenic and cardiometabolic consequences that a single cortisol measurement cannot identify\u003c\/li\u003e\n\u003cli\u003eSHBG is the bioavailability gatekeeper for testosterone - essential for calculating free testosterone and identifying why men with normal total testosterone have full androgenic deficiency symptoms\u003c\/li\u003e\n\u003cli\u003eThyroid dysfunction suppresses Leydig cell testosterone production and elevates SHBG - cortisol-driven T3 suppression produces identical symptoms with a normal TSH; Hashimoto's is present years before TSH becomes abnormal\u003c\/li\u003e\n\u003cli\u003eInsulin resistance and testosterone decline are mutually reinforcing, SHBG-mediated, and thyroid-compounded - fasting insulin is the earliest detectable marker, elevated years before HbA1c becomes abnormal\u003c\/li\u003e\n\u003cli\u003ehsCRP is the convergence biomarker of all four systems - elevated simultaneously by low free testosterone, SHBG-mediated androgenic deficiency, cortisol dysregulation, insulin resistance, and Hashimoto's autoimmunity\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\u003cp\u003eEmail us at \u003ca href=\"mailto:info@hormonelab.co.uk\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours.\u003c\/p\u003e\u003ch2\u003eHow It Works\u003c\/h2\u003e\u003col\u003e\n\u003cli\u003eOrder your kit - delivered directly to your door\u003c\/li\u003e\n\u003cli\u003eCollect saliva at four time points (morning before 9am, noon, evening, night) and blood spot via finger-prick\u003c\/li\u003e\n\u003cli\u003ePost your samples to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your full report by email within 3-5 working days\u003c\/li\u003e\n\u003c\/ol\u003e\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eAll 24 marker results with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eVisual cortisol rhythm chart showing your full four-point daily curve\u003c\/li\u003e\n\u003cli\u003eVisual charts for all sex hormones, SHBG, the full thyroid panel, and all six cardiometabolic markers\u003c\/li\u003e\n\u003cli\u003eIntegrated clinical interpretation of how cortisol rhythm, testosterone, SHBG, estradiol, thyroid markers, and cardiometabolic results interact as a single male hormonal-metabolic system by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003eSHBG-adjusted free testosterone bioavailability assessment\u003c\/li\u003e\n\u003cli\u003eCortisol-thyroid T3 and Hashimoto's autoimmunity assessment in cortisol, insulin, and SHBG context\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included - no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e - a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003ePioneers of at-home \u003cstrong\u003edried blood spot (DBS)\u003c\/strong\u003e and saliva hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePersonalised reference ranges based on age and sex\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eThrough our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to people across the UK and Europe - from the comfort of home.\u003c\/p\u003e\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eWhy do I need SHBG tested alongside testosterone?\u003c\/strong\u003e\u003cbr\u003eSHBG binds and inactivates testosterone. A man with elevated SHBG - from cortisol, thyroid disease, or estradiol excess - has full androgenic deficiency symptoms despite a normal total testosterone. Without SHBG, testosterone results cannot be accurately interpreted or free testosterone calculated.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWhy is a 4-point cortisol rhythm more informative than a single measurement?\u003c\/strong\u003e\u003cbr\u003eA single value cannot identify whether the morning awakening response is blunted, whether cortisol peaks at midday or evening, or whether night cortisol is suppressing overnight testosterone production. The four-point rhythm identifies exactly which phase is driving androgenic, SHBG, thyroid, and metabolic components of your symptoms.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCan I use this test if I am on TRT or levothyroxine?\u003c\/strong\u003e\u003cbr\u003eYes - this is the most appropriate test for men on TRT. It measures SHBG, estradiol, cortisol rhythm, thyroid markers, and cardiometabolic markers alongside testosterone, providing the complete picture needed for safe and effective TRT monitoring.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eIs this suitable for men with Hashimoto's or suspected thyroid disease?\u003c\/strong\u003e\u003cbr\u003eYes - TPO and Tg antibodies are assessed alongside the 4-point cortisol rhythm and insulin markers that directly drive Hashimoto's progression, plus SHBG that reflects thyroid-driven testosterone inactivation.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. There are no additional charges. You are only responsible for posting your samples to the laboratory.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":57961452274045,"sku":"2028-M","price":376.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/SalivaandBloodSpotHormoneTestKit.webp?v=1785073903"},{"product_id":"male-cardiometabolic-hormone-profile","title":"Male CardioMetabolic \u0026 Hormone Profile","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e SB-645 | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Saliva + Dried Blood Spot | \u003cstrong\u003eTechnology:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults Time:\u003c\/strong\u003e 3–5 Working Days After Laboratory Receives Sample | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eHormone Specialist Doctor Interpretation:\u003c\/strong\u003e Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\n\u003ch2\u003eWhat Does This Test Measure?\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSaliva — 4-Point Cortisol Profile:\u003c\/strong\u003e Morning, Noon, Evening, and Night Cortisol.\u003cbr\u003e\n\u003cstrong\u003eBlood Spot — Sex Hormones \u0026amp; SHBG (LC-MS\/MS):\u003c\/strong\u003e Estradiol (E2), Estriol (E3), Estrone (E1), Progesterone, Testosterone, DHEAS, Cortisol, SHBG.\u003cbr\u003e\n\u003cstrong\u003eBlood Spot — CardioMetabolic Panel:\u003c\/strong\u003e Fasting Insulin, HbA1c, HDL Cholesterol, Triglycerides, Total Cholesterol, hsCRP.\u003cbr\u003e\n18 markers total — a clinically integrated picture of the cortisol rhythm, androgenic balance, hormone bioavailability, and cardiometabolic risk in a single at-home kit.\u003c\/p\u003e\n\n\u003ch2\u003eRelated Symptoms\u003c\/h2\u003e\n\u003cp\u003ePersistent fatigue, unexplained abdominal weight gain, low libido, erectile dysfunction, poor exercise recovery, brain fog, low mood, sugar cravings, energy crashes, elevated cholesterol or triglycerides on previous testing, insomnia, chronic stress, burnout, or symptoms of low testosterone with normal standard blood results.\u003c\/p\u003e\n\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003ePersistent fatigue that does not improve with rest or sleep\u003c\/li\u003e\n\u003cli\u003eUnexplained weight gain, particularly around the abdomen\u003c\/li\u003e\n\u003cli\u003eLow libido, erectile dysfunction, or reduced sexual performance\u003c\/li\u003e\n\u003cli\u003ePoor recovery from exercise or sustained high-pressure workload\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor concentration, or low mood\u003c\/li\u003e\n\u003cli\u003eSugar cravings, energy crashes, or afternoon slumps\u003c\/li\u003e\n\u003cli\u003eElevated cholesterol, triglycerides, or blood sugar on previous testing\u003c\/li\u003e\n\u003cli\u003eInsomnia, night waking, or unrefreshing sleep\u003c\/li\u003e\n\u003cli\u003eTold testosterone is “normal” but continuing to experience androgenic symptoms\u003c\/li\u003e\n\u003cli\u003eCurrently on TRT and wanting to monitor SHBG, estradiol, and cardiometabolic markers\u003c\/li\u003e\n\u003cli\u003eFamily history of heart disease, diabetes, or metabolic syndrome\u003c\/li\u003e\n\u003cli\u003eMen over 35 seeking a comprehensive hormonal and metabolic health baseline\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy This Test Is Particularly Important for Men\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eThe 4-point cortisol rhythm determines free testosterone via SHBG — cortisol elevation at any time point triggers hepatic SHBG synthesis, binding and inactivating testosterone regardless of how much the testes produce\u003c\/li\u003e\n\u003cli\u003eSHBG is essential for calculating free testosterone — two men with identical total testosterone can have completely different androgenic status depending on SHBG\u003c\/li\u003e\n\u003cli\u003eCortisol drives every cardiometabolic risk marker simultaneously — insulin resistance, visceral fat, estradiol excess, triglyceride elevation, HDL suppression, and hsCRP rise are all cortisol-mediated\u003c\/li\u003e\n\u003cli\u003eFasting insulin is the earliest detectable marker of insulin resistance — elevated years before HbA1c becomes abnormal, directly linked to erectile dysfunction and declining androgenic function\u003c\/li\u003e\n\u003cli\u003ehsCRP is the convergence biomarker of cortisol dysregulation, SHBG-mediated testosterone deficiency, and insulin resistance — a stronger independent predictor of cardiovascular events than LDL cholesterol\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca href=\"mailto:info@hormonelab.co.uk\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours.\u003c\/p\u003e\n\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered directly to your door\u003c\/li\u003e\n\u003cli\u003eCollect saliva at four time points (morning before 9am, noon, evening, night) and blood spot via finger-prick\u003c\/li\u003e\n\u003cli\u003ePost your samples to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your full report by email within 3–5 working days\u003c\/li\u003e\n\u003c\/ol\u003e\n\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll 18 marker results with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eVisual cortisol rhythm chart showing your full four-point daily curve\u003c\/li\u003e\n\u003cli\u003eCharts for all sex hormones, SHBG, and all six cardiometabolic markers\u003c\/li\u003e\n\u003cli\u003eSHBG-adjusted free testosterone bioavailability assessment\u003c\/li\u003e\n\u003cli\u003eIntegrated clinical interpretation by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePioneers of at-home \u003cstrong\u003edried blood spot (DBS)\u003c\/strong\u003e and saliva hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePersonalised reference ranges based on age and sex\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThrough our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to people across the UK and Europe — from the comfort of home.\u003c\/p\u003e\n\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDoes this test include thyroid assessment?\u003c\/strong\u003e\u003cbr\u003eNo. This profile assesses the cortisol rhythm, sex hormones, SHBG, and cardiometabolic markers. For thyroid assessment alongside this panel, see the Male Comprehensive Hormone, Thyroid \u0026amp; CardioMetabolic Profile.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy do I need SHBG alongside testosterone?\u003c\/strong\u003e\u003cbr\u003eSHBG binds and inactivates testosterone. A man with normal total testosterone but elevated SHBG — caused by cortisol, estradiol excess, age, or caloric restriction — has full androgenic deficiency symptoms despite a “normal” result. SHBG is the most common reason men are told their testosterone is normal but continue to experience fatigue and low libido.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is a 4-point cortisol more informative than a single measurement?\u003c\/strong\u003e\u003cbr\u003eA single cortisol value cannot identify which part of the day is driving androgenic or cardiometabolic deterioration. Each time point — morning, noon, evening, night — has different hormonal and metabolic consequences and different intervention targets.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan I use this test if I am on TRT?\u003c\/strong\u003e\u003cbr\u003eYes. This test is particularly valuable for men on TRT wanting to monitor SHBG, estradiol, cortisol rhythm, and cardiometabolic markers alongside testosterone.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. There are no additional charges. You are only responsible for posting your samples to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":57961607725437,"sku":"1020","price":341.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/SalivaandBloodSpotHormoneTestKit.webp?v=1785073903"},{"product_id":"male-comprehensive-hormone-profile-i","title":"Male Comprehensive Hormone Profile I","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e SB-644 | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Saliva + Dried Blood Spot | \u003cstrong\u003eTechnology:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults Time:\u003c\/strong\u003e 3–5 Working Days After Laboratory Receives Sample | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eHormone Specialist Doctor Interpretation:\u003c\/strong\u003e Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\n\u003ch2\u003eWhat Does This Test Measure?\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSaliva — 4-Point Cortisol Profile:\u003c\/strong\u003e Morning, Noon, Evening, and Night Cortisol.\u003cbr\u003e\n\u003cstrong\u003eBlood Spot — Sex Hormones + SHBG (LC-MS\/MS):\u003c\/strong\u003e Estradiol (E2), Estriol (E3), Estrone (E1), Progesterone, Testosterone, DHEAS, Cortisol, SHBG.\u003cbr\u003e\n\u003cstrong\u003eBlood Spot — Full Thyroid Panel:\u003c\/strong\u003e TSH, Free T3, Free T4, Total T4, TPO Antibodies, Thyroglobulin Antibodies.\u003cbr\u003e\n18 markers total — a complete picture of the daily cortisol rhythm, androgenic balance including SHBG, and autoimmune thyroid function in a single at-home kit.\u003c\/p\u003e\n\n\u003ch2\u003eRelated Symptoms\u003c\/h2\u003e\n\u003cp\u003ePersistent fatigue, unexplained weight gain, low libido, erectile dysfunction, poor exercise recovery, brain fog, low mood, feeling cold, dry skin, hair thinning, insomnia, chronic stress, burnout, symptoms of low testosterone with normal standard blood results, or told testosterone is “normal” but symptoms persist.\u003c\/p\u003e\n\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003ePersistent fatigue that does not improve with rest or sleep\u003c\/li\u003e\n\u003cli\u003eUnexplained weight gain, particularly around the abdomen\u003c\/li\u003e\n\u003cli\u003eLow libido, erectile dysfunction, or reduced sexual performance\u003c\/li\u003e\n\u003cli\u003ePoor recovery from exercise or sustained high workload\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor concentration, or low mood\u003c\/li\u003e\n\u003cli\u003eFeeling cold, dry skin, or hair thinning\u003c\/li\u003e\n\u003cli\u003eInsomnia, night waking, or unrefreshing sleep\u003c\/li\u003e\n\u003cli\u003eChronic stress or burnout\u003c\/li\u003e\n\u003cli\u003eTold testosterone is “normal” but symptoms of androgen deficiency persist (elevated SHBG is frequently the explanation)\u003c\/li\u003e\n\u003cli\u003eCurrently on TRT and wanting to monitor SHBG, thyroid, and estradiol alongside testosterone\u003c\/li\u003e\n\u003cli\u003eDiagnosed or suspected Hashimoto’s thyroiditis or autoimmune thyroid disease\u003c\/li\u003e\n\u003cli\u003eOn levothyroxine and wanting complete thyroid monitoring alongside SHBG and sex hormone levels\u003c\/li\u003e\n\u003cli\u003eMen who want the complete cortisol-SHBG-testosterone-thyroid picture without a cardiometabolic panel\u003c\/li\u003e\n\u003cli\u003eMen over 35 seeking a comprehensive androgenic, SHBG, cortisol rhythm, and thyroid health baseline\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy This Test Is Particularly Important for Men\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eThe 4-point cortisol rhythm is the master regulator of SHBG, free testosterone, and thyroid T3 activation — each time point has distinct androgenic and thyroid consequences that a single cortisol measurement cannot identify\u003c\/li\u003e\n\u003cli\u003eSHBG is the most commonly missed cause of low testosterone symptoms in men with “normal” blood results — elevated by cortisol, thyroid disease, estradiol excess, age, and caloric restriction\u003c\/li\u003e\n\u003cli\u003eThyroid dysfunction suppresses Leydig cell testosterone production and elevates SHBG — cortisol-driven T3 suppression produces identical symptoms with a normal TSH; Hashimoto’s is present years before TSH becomes abnormal\u003c\/li\u003e\n\u003cli\u003eNight cortisol elevation suppresses overnight testosterone production and worsens Hashimoto’s autoimmune activity simultaneously — detectable only by the 4-point cortisol assessment\u003c\/li\u003e\n\u003cli\u003eBoth TPO and Tg antibodies are required for complete Hashimoto’s screening — some men have elevated Tg antibodies with normal TPO\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eHow This Profile Differs From Other Tests\u003c\/h2\u003e\n\u003cp\u003eThe \u003cstrong\u003eMale Comprehensive Hormone Profile I (SB-644)\u003c\/strong\u003e provides the 4-point cortisol rhythm, full LC-MS\/MS sex hormones + SHBG, and full thyroid panel — without the cardiometabolic panel. It is the ideal choice for men who want the complete cortisol-SHBG-testosterone-thyroid assessment, or who are adding targeted metabolic testing separately. For the cardiometabolic panel alongside this assessment, see the \u003cstrong\u003eMale Comprehensive Hormone, Thyroid \u0026amp; CardioMetabolic Profile (SB-646M)\u003c\/strong\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca href=\"mailto:info@hormonelab.co.uk\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours.\u003c\/p\u003e\n\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered directly to your door\u003c\/li\u003e\n\u003cli\u003eCollect saliva at four time points (morning before 9am, noon, evening, night) and blood spot via finger-prick\u003c\/li\u003e\n\u003cli\u003ePost your samples to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your full report by email within 3–5 working days\u003c\/li\u003e\n\u003c\/ol\u003e\n\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll 18 marker results with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eVisual cortisol rhythm chart showing your full four-point daily curve\u003c\/li\u003e\n\u003cli\u003eVisual charts for all sex hormones, SHBG, and the full thyroid panel\u003c\/li\u003e\n\u003cli\u003eIntegrated clinical interpretation of how cortisol rhythm, testosterone, SHBG, estradiol, and thyroid markers interact as a single male hormonal system by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003eSHBG-adjusted free testosterone bioavailability assessment\u003c\/li\u003e\n\u003cli\u003eCortisol-thyroid T3 and Hashimoto’s autoimmunity assessment in cortisol and SHBG context\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePioneers of at-home \u003cstrong\u003edried blood spot (DBS)\u003c\/strong\u003e and saliva hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePersonalised reference ranges based on age and sex\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThrough our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to people across the UK and Europe — from the comfort of home.\u003c\/p\u003e\n\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDoes this test include cardiometabolic markers?\u003c\/strong\u003e\u003cbr\u003eNo. This profile covers the cortisol rhythm, sex hormones, SHBG, and full thyroid panel. For fasting insulin, HbA1c, HDL, triglycerides, cholesterol, and hsCRP alongside this panel, see the \u003cstrong\u003eMale Comprehensive Hormone, Thyroid \u0026amp; CardioMetabolic Profile (SB-646M)\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is TSH alone not enough?\u003c\/strong\u003e\u003cbr\u003eTSH measures the pituitary signal to the thyroid, not the active T3 reaching cells. Cortisol-driven T3 suppression produces functional hypothyroidism and Leydig cell testosterone suppression with a normal TSH. Hashimoto’s causes progressive thyroid damage for years before TSH becomes abnormal. SHBG elevation from thyroid disease further inactivates testosterone. All three patterns are invisible to TSH alone.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy do I need SHBG alongside testosterone?\u003c\/strong\u003e\u003cbr\u003eSHBG binds and inactivates testosterone. A man with elevated SHBG — from cortisol, thyroid disease, or estradiol excess — has full androgenic deficiency symptoms despite a normal total testosterone. This panel identifies both the SHBG level and, through the 4-point cortisol rhythm and thyroid panel, the most likely mechanism driving it.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan I use this test if I am on TRT or levothyroxine?\u003c\/strong\u003e\u003cbr\u003eYes. This test monitors SHBG, estradiol, thyroid function, and cortisol rhythm alongside testosterone — essential for safe TRT management and accurate levothyroxine dosing.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. There are no additional charges. You are only responsible for posting your samples to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":57961680306557,"sku":"1021","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/SalivaandBloodSpotHormoneTestKit.webp?v=1785073903"},{"product_id":"male-hormone-health-test-kit","title":"Male Hormone Health Test","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e SB-643 | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Dried Blood Spot + Saliva | \u003cstrong\u003eTechnology:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults Time:\u003c\/strong\u003e 3–5 Working Days After Laboratory Receives Sample | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eHormone Specialist Doctor Interpretation:\u003c\/strong\u003e Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\n\u003ch2\u003eWhat Does This Test Measure?\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSaliva — 4-Point Cortisol:\u003c\/strong\u003e Morning, Noon, Evening, and Night Cortisol.\u003cbr\u003e\u003cstrong\u003eBlood Spot — Full Sex Hormone Panel (LC-MS\/MS):\u003c\/strong\u003e Estradiol (E2), Estriol (E3), Estrone (E1), Progesterone, Testosterone, DHEAS, Cortisol, SHBG.\u003cbr\u003e15 markers total — a clinically complete picture of androgenic health, adrenal stress load, estrogen balance, and hormone bioavailability in a single at-home kit.\u003c\/p\u003e\n\n\u003ch2\u003eRelated Symptoms\u003c\/h2\u003e\n\u003cp\u003ePersistent fatigue, low libido, erectile dysfunction, unexplained abdominal weight gain, poor exercise recovery, brain fog, low mood, insomnia, night waking, chronic stress, burnout, acne, scalp hair loss, gynaecomastia, or symptoms of low testosterone with normal standard blood results.\u003c\/p\u003e\n\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003ePersistent fatigue that does not improve with rest or sleep\u003c\/li\u003e\n\u003cli\u003eLow libido, erectile dysfunction, or reduced sexual performance\u003c\/li\u003e\n\u003cli\u003eUnexplained weight gain, particularly around the abdomen\u003c\/li\u003e\n\u003cli\u003ePoor recovery from exercise or sustained high-pressure workload\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor concentration, or low mood\u003c\/li\u003e\n\u003cli\u003eInsomnia, night waking, or unrefreshing sleep\u003c\/li\u003e\n\u003cli\u003eChronic stress or burnout\u003c\/li\u003e\n\u003cli\u003eAcne, scalp hair loss, or gynaecomastia\u003c\/li\u003e\n\u003cli\u003eSymptoms of low testosterone with normal or inconclusive standard blood results\u003c\/li\u003e\n\u003cli\u003eTold testosterone is normal but androgenic symptoms persist (elevated SHBG is frequently the explanation)\u003c\/li\u003e\n\u003cli\u003eCurrently on TRT and wanting to monitor estradiol balance, SHBG status, and cortisol rhythm alongside testosterone\u003c\/li\u003e\n\u003cli\u003eMen over 35 seeking a comprehensive androgenic and adrenal health baseline\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy This Test Is Particularly Important for Men\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSHBG is the most commonly missed cause of low testosterone symptoms in men with “normal” blood results — high SHBG binds and inactivates testosterone regardless of total production level; low SHBG releases excess free testosterone and estradiol, raising cardiovascular and prostate risk\u003c\/li\u003e\n\u003cli\u003eThe 4-point cortisol profile reveals the complete daily adrenal rhythm — each time point (morning, noon, evening, night) has distinct consequences for testosterone, SHBG, and estradiol balance that a single cortisol measurement cannot identify\u003c\/li\u003e\n\u003cli\u003eCortisol is the primary driver of SHBG elevation — chronic cortisol excess triggers hepatic SHBG synthesis, inactivating testosterone and amplifying androgenic deficiency symptoms even when total testosterone is within range\u003c\/li\u003e\n\u003cli\u003eEstradiol excess from visceral fat and aromatase activity suppresses testosterone, drives gynaecomastia, causes fat accumulation, and independently raises cardiovascular risk — measuring all three estrogens alongside SHBG reveals the full oestrogenic load\u003c\/li\u003e\n\u003cli\u003eDHEAS is the adrenal androgenic reserve marker — a sustained indicator of chronic stress and adrenal depletion that a single cortisol value cannot capture\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca href=\"mailto:info@hormonelab.co.uk\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours.\u003c\/p\u003e\n\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered directly to your door\u003c\/li\u003e\n\u003cli\u003eCollect saliva at four time points (morning before 9am, noon, evening, night) and blood spot via finger-prick\u003c\/li\u003e\n\u003cli\u003ePost your samples to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your full report by email within 3–5 working days\u003c\/li\u003e\n\u003c\/ol\u003e\n\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll 15 marker results with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eVisual charts for your 4-point cortisol curve and full sex hormone panel including SHBG\u003c\/li\u003e\n\u003cli\u003eClinical interpretation of free vs bound testosterone and your estradiol-to-testosterone ratio\u003c\/li\u003e\n\u003cli\u003eWritten interpretation by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePioneers of at-home \u003cstrong\u003edried blood spot (DBS)\u003c\/strong\u003e and saliva hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePersonalised reference ranges based on age and sex\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThrough our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to people across the UK and Europe — from the comfort of home.\u003c\/p\u003e\n\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is SHBG important for men?\u003c\/strong\u003e\u003cbr\u003eSHBG determines how much testosterone is free and active versus bound and unavailable. Two men with the same total testosterone can have very different free testosterone depending on their SHBG — one functionally deficient despite “normal” results, one with excess free hormone driving prostate and cardiovascular risk. Without SHBG, a testosterone result cannot explain your symptoms.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy do men need estrogen tested?\u003c\/strong\u003e\u003cbr\u003eMen produce Estradiol (E2) through aromatase conversion of testosterone — a process that increases with visceral fat, alcohol, and ageing. Excess Estradiol (E2) suppresses testosterone, causes gynaecomastia, and drives fat accumulation. Measuring all three estrogens alongside testosterone and SHBG reveals the full oestrogenic load and its impact on androgenic balance.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan I use this test if I am on TRT?\u003c\/strong\u003e\u003cbr\u003eYes. This test is particularly valuable for men on TRT who want to understand their estradiol balance, SHBG status, and cortisol pattern alongside testosterone. TRT increases aromatisation and can significantly alter SHBG — making a comprehensive panel essential for safe monitoring.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy measure cortisol at four time points?\u003c\/strong\u003e\u003cbr\u003eA single cortisol measurement cannot distinguish between adrenal burnout, high morning reactivity, evening elevation, or night excess — each with different effects on testosterone and SHBG. The 4-point profile captures the full daily adrenal rhythm.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. There are no additional charges. You are only responsible for posting your samples to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":57961734177149,"sku":"2022","price":257.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/SalivaandBloodSpotHormoneTestKit.webp?v=1785073903"},{"product_id":"male-cardiometabolic-thyroid-test-kit","title":"Male CardioMetabolic \u0026 Thyroid Test Kit","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e SB-642 | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Saliva + Dried Blood Spot | \u003cstrong\u003eTechnology:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults Time:\u003c\/strong\u003e 3–5 Working Days After Laboratory Receives Sample | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eHormone Specialist Doctor Interpretation:\u003c\/strong\u003e Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\n\u003ch2\u003eWhat Does This Test Measure?\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSaliva — 4-Point Cortisol Profile:\u003c\/strong\u003e Morning, Noon, Evening, and Night Cortisol.\u003cbr\u003e\n\u003cstrong\u003eBlood Spot — Full Thyroid Panel:\u003c\/strong\u003e TSH, Free T3, Free T4, Total T4, TPO Antibodies, Thyroglobulin Antibodies.\u003cbr\u003e\n\u003cstrong\u003eBlood Spot — CardioMetabolic Panel:\u003c\/strong\u003e Fasting Insulin, HbA1c, HDL Cholesterol, Triglycerides, Total Cholesterol, hsCRP.\u003cbr\u003e\n18 markers total — a clinically complete picture of thyroid function including autoimmune markers, cardiometabolic risk, and the full daily cortisol rhythm in a single at-home kit.\u003c\/p\u003e\n\n\u003ch2\u003eRelated Symptoms\u003c\/h2\u003e\n\u003cp\u003ePersistent fatigue, unexplained weight gain, brain fog, low mood, cold intolerance, hair thinning, low libido, erectile dysfunction, poor exercise recovery, elevated cholesterol or triglycerides on previous testing, blood sugar crashes, sugar cravings, chronic stress, burnout, or insomnia.\u003c\/p\u003e\n\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003ePersistent fatigue or exhaustion that does not improve with rest\u003c\/li\u003e\n\u003cli\u003eUnexplained weight gain or difficulty losing body fat\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor concentration, or low mood\u003c\/li\u003e\n\u003cli\u003eFeeling cold, hair thinning, dry skin, or slow metabolism\u003c\/li\u003e\n\u003cli\u003eElevated cholesterol, triglycerides, or blood sugar on previous testing\u003c\/li\u003e\n\u003cli\u003eSugar cravings, energy crashes, or afternoon slumps\u003c\/li\u003e\n\u003cli\u003eInsomnia, night waking, or unrefreshing sleep\u003c\/li\u003e\n\u003cli\u003eChronic stress or burnout\u003c\/li\u003e\n\u003cli\u003eLow libido or poor exercise recovery without a full sex hormone assessment\u003c\/li\u003e\n\u003cli\u003eDiagnosed or suspected Hashimoto's thyroiditis or autoimmune thyroid disease\u003c\/li\u003e\n\u003cli\u003eOn levothyroxine and wanting complete thyroid monitoring alongside cortisol and cardiometabolic markers\u003c\/li\u003e\n\u003cli\u003eMen wanting targeted thyroid and metabolic assessment without a full sex hormone panel\u003c\/li\u003e\n\u003cli\u003eFamily history of thyroid disease, heart disease, or diabetes\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy This Test Is Particularly Important for Men\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eCortisol is the primary driver of thyroid T3 suppression and cardiometabolic deterioration simultaneously — elevated cortisol at any time point impairs T4-to-T3 conversion, drives insulin resistance, raises triglycerides, suppresses HDL, and elevates hsCRP\u003c\/li\u003e\n\u003cli\u003eTSH alone misses three critical patterns — cortisol-driven T3 suppression, early thyroid insufficiency, and Hashimoto's autoimmunity; both TPO and Tg antibodies are required as some men have elevated Tg with normal TPO\u003c\/li\u003e\n\u003cli\u003eFasting insulin is the earliest detectable marker of insulin resistance — elevated years before HbA1c becomes abnormal, directly linked to visceral fat, aromatase activity, and cardiovascular risk\u003c\/li\u003e\n\u003cli\u003eThe 4-point cortisol profile identifies which phase of the day is driving thyroid suppression and cardiometabolic deterioration — a single cortisol measurement cannot reveal this\u003c\/li\u003e\n\u003cli\u003ehsCRP is the convergence biomarker of cortisol dysregulation, thyroid dysfunction, and insulin resistance — a stronger independent predictor of cardiovascular events than LDL cholesterol\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca href=\"mailto:info@hormonelab.co.uk\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours.\u003c\/p\u003e\n\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered directly to your door\u003c\/li\u003e\n\u003cli\u003eCollect saliva at four time points (morning before 9am, noon, evening, night) and blood spot via finger-prick\u003c\/li\u003e\n\u003cli\u003ePost your samples to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your full report by email within 3–5 working days\u003c\/li\u003e\n\u003c\/ol\u003e\n\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll 18 marker results with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eVisual cortisol rhythm chart showing your full four-point daily curve\u003c\/li\u003e\n\u003cli\u003eVisual charts for the full thyroid panel and all six cardiometabolic markers\u003c\/li\u003e\n\u003cli\u003eIntegrated clinical interpretation of how cortisol rhythm, thyroid function, and cardiometabolic markers interact by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePioneers of at-home \u003cstrong\u003edried blood spot (DBS)\u003c\/strong\u003e and saliva hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePersonalised reference ranges based on age and sex\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThrough our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to people across the UK and Europe — from the comfort of home.\u003c\/p\u003e\n\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhy test thyroid, cortisol, and cardiometabolic markers together?\u003c\/strong\u003e\u003cbr\u003eThese systems converge on metabolic and cardiovascular health in men. Cortisol suppresses T3 conversion and drives insulin resistance simultaneously; thyroid insufficiency raises cardiovascular risk; insulin resistance drives visceral fat and inflammatory load. Testing all together identifies root causes that single-system tests miss.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes this test include sex hormones?\u003c\/strong\u003e\u003cbr\u003eNo. This profile focuses on the thyroid, cortisol rhythm, and cardiometabolic panel. For sex hormones and SHBG alongside these markers, see the Male Comprehensive Hormone, Thyroid \u0026amp; CardioMetabolic Profile (SB-646M).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan I use this test if I am on TRT or levothyroxine?\u003c\/strong\u003e\u003cbr\u003eYes. This test is particularly valuable for men on TRT or levothyroxine wanting to monitor thyroid function, cortisol rhythm, and cardiometabolic markers. Levothyroxine dosing is most accurate when FT3, FT4, and antibodies are assessed alongside the cortisol that impairs T3 conversion.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is fasting insulin and why does it matter?\u003c\/strong\u003e\u003cbr\u003eFasting insulin is the earliest detectable marker of insulin resistance — elevated years before HbA1c or fasting glucose becomes abnormal. Elevated insulin drives visceral fat, raises aromatase activity, and independently increases cardiovascular risk.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. There are no additional charges. You are only responsible for posting your samples to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":57961782804861,"sku":"20255","price":271.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/SalivaandBloodSpotHormoneTestKit.webp?v=1785073903"},{"product_id":"male-cardiometabolic-cortisol-test-kit","title":"Male CardioMetabolic \u0026 Cortisol Test Kit","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e SB-641 | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Saliva + Dried Blood Spot | \u003cstrong\u003eTechnology:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults Time:\u003c\/strong\u003e 3–5 Working Days After Laboratory Receives Sample | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eHormone Specialist Doctor Interpretation:\u003c\/strong\u003e Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\n\u003ch2\u003eWhat Does This Test Measure?\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSaliva — 4-Point Cortisol Profile:\u003c\/strong\u003e Morning, Noon, Evening, and Night Cortisol.\u003cbr\u003e\n\u003cstrong\u003eBlood Spot — CardioMetabolic Panel:\u003c\/strong\u003e Fasting Insulin, HbA1c, HDL Cholesterol, Triglycerides, Total Cholesterol, hsCRP.\u003cbr\u003e\n10 markers total — an integrated assessment of the stress-metabolism axis and cardiovascular health in a single at-home kit.\u003c\/p\u003e\n\n\u003ch2\u003eRelated Symptoms\u003c\/h2\u003e\n\u003cp\u003ePersistent fatigue, unexplained abdominal weight gain, sugar cravings, energy crashes, poor exercise recovery, elevated cholesterol or triglycerides on previous testing, blood sugar irregularities, chronic stress, burnout, insomnia, night waking, or brain fog.\u003c\/p\u003e\n\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003ePersistent fatigue or exhaustion that does not improve with rest\u003c\/li\u003e\n\u003cli\u003eUnexplained weight gain, particularly around the abdomen\u003c\/li\u003e\n\u003cli\u003eSugar cravings, energy crashes, or afternoon slumps\u003c\/li\u003e\n\u003cli\u003eElevated cholesterol, triglycerides, or blood sugar on previous testing\u003c\/li\u003e\n\u003cli\u003ePoor exercise recovery or reduced physical performance\u003c\/li\u003e\n\u003cli\u003eInsomnia, night waking, or unrefreshing sleep\u003c\/li\u003e\n\u003cli\u003eChronic stress or burnout\u003c\/li\u003e\n\u003cli\u003eBrain fog or low mood\u003c\/li\u003e\n\u003cli\u003eMen wanting a targeted cortisol and cardiometabolic assessment without a full sex hormone or thyroid panel\u003c\/li\u003e\n\u003cli\u003eCurrently on TRT and wanting to understand whether cortisol or insulin resistance is limiting therapy effectiveness\u003c\/li\u003e\n\u003cli\u003eFamily history of heart disease, diabetes, or metabolic syndrome\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy This Test Is Particularly Important for Men\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eCortisol is the primary hormonal driver of visceral fat, insulin resistance, testosterone suppression, and cardiovascular inflammation in men — four pathways assessed simultaneously by this panel\u003c\/li\u003e\n\u003cli\u003eThe 4-point cortisol profile identifies which phase of the day is driving cardiometabolic deterioration — morning, midday, evening, or night — enabling targeted intervention that a single cortisol value cannot provide\u003c\/li\u003e\n\u003cli\u003eFasting insulin is the earliest detectable marker of insulin resistance — elevated years before HbA1c becomes abnormal, directly promoting visceral fat, aromatase activity, and cardiovascular risk\u003c\/li\u003e\n\u003cli\u003ehsCRP is the convergence biomarker of cortisol dysregulation and insulin resistance — a stronger independent predictor of cardiovascular events than LDL cholesterol\u003c\/li\u003e\n\u003cli\u003eNight cortisol elevation suppresses overnight testosterone production and drives fasting insulin elevation simultaneously — detectable only by the 4-point assessment\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca href=\"mailto:info@hormonelab.co.uk\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours.\u003c\/p\u003e\n\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered directly to your door\u003c\/li\u003e\n\u003cli\u003eCollect saliva at four time points (morning before 9am, noon, evening, night) and blood spot via finger-prick\u003c\/li\u003e\n\u003cli\u003ePost your samples to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your full report by email within 3–5 working days\u003c\/li\u003e\n\u003c\/ol\u003e\n\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll 10 marker results with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eVisual cortisol rhythm chart showing your full four-point daily curve\u003c\/li\u003e\n\u003cli\u003eVisual charts for all six cardiometabolic markers\u003c\/li\u003e\n\u003cli\u003eIntegrated clinical interpretation of how cortisol rhythm and cardiometabolic markers interact by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePioneers of at-home \u003cstrong\u003edried blood spot (DBS)\u003c\/strong\u003e and saliva hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePersonalised reference ranges based on age and sex\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThrough our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to people across the UK and Europe — from the comfort of home.\u003c\/p\u003e\n\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhy test cortisol and cardiometabolic markers together?\u003c\/strong\u003e\u003cbr\u003eCortisol is the primary hormonal driver of visceral fat, insulin resistance, and cardiovascular inflammation in men. Assessing both together reveals the root cause and full extent of metabolic dysfunction that treating each marker in isolation misses.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes this test include sex hormones or thyroid markers?\u003c\/strong\u003e\u003cbr\u003eNo. This profile focuses on the 4-point cortisol rhythm and cardiometabolic panel. For thyroid assessment alongside this panel, see the Male CardioMetabolic \u0026amp; Thyroid Test Kit (SB-642). For sex hormones and SHBG, see the Male Comprehensive Hormone, Thyroid \u0026amp; CardioMetabolic Profile (SB-646M).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan I use this test if I am on TRT?\u003c\/strong\u003e\u003cbr\u003eYes. This test helps men on TRT understand whether cortisol dysregulation or insulin resistance is limiting therapy effectiveness or contributing to ongoing metabolic symptoms.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is fasting insulin and why does it matter?\u003c\/strong\u003e\u003cbr\u003eFasting insulin is the earliest detectable marker of insulin resistance — elevated years before HbA1c becomes abnormal. In men, elevated insulin promotes visceral fat, drives estradiol conversion via aromatase, and independently raises cardiovascular risk.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. There are no additional charges. You are only responsible for posting your samples to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":57961888317821,"sku":"2023","price":230.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/SalivaandBloodSpotHormoneTestKit.webp?v=1785073903"},{"product_id":"male-thyroid-cortisol-test-kit","title":"Male Thyroid \u0026 Cortisol Test Kit","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e SB-640 | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Saliva + Dried Blood Spot | \u003cstrong\u003eTechnology:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults Time:\u003c\/strong\u003e 3–5 Working Days After Laboratory Receives Sample | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eHormone Specialist Doctor Interpretation:\u003c\/strong\u003e Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Adults and Children | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\n\u003ch2\u003eWhat Does This Test Measure?\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSaliva — 4-Point Cortisol Profile:\u003c\/strong\u003e Morning, Noon, Evening, and Night Cortisol.\u003cbr\u003e\n\u003cstrong\u003eBlood Spot — Full Thyroid Panel:\u003c\/strong\u003e TSH, Free T3, Free T4, Total T4, TPO Antibodies, Thyroglobulin Antibodies.\u003cbr\u003e\n10 markers total — a clinically complete assessment of thyroid function including autoimmune markers and the full daily cortisol rhythm in a single at-home kit.\u003c\/p\u003e\n\n\u003ch2\u003eRelated Symptoms\u003c\/h2\u003e\n\u003cp\u003ePersistent fatigue, unexplained weight gain, brain fog, low mood, cold intolerance, hair thinning, low libido, poor exercise recovery, chronic stress, burnout, insomnia, night waking, or symptoms of low testosterone with inconclusive blood results.\u003c\/p\u003e\n\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003ePersistent fatigue that does not improve with rest or sleep\u003c\/li\u003e\n\u003cli\u003eUnexplained weight gain or difficulty losing body fat\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor concentration, or low mood\u003c\/li\u003e\n\u003cli\u003eFeeling cold, hair thinning, dry skin, or slow metabolism\u003c\/li\u003e\n\u003cli\u003eInsomnia, night waking, or unrefreshing sleep\u003c\/li\u003e\n\u003cli\u003eChronic stress or burnout\u003c\/li\u003e\n\u003cli\u003eLow libido or poor exercise recovery without full sex hormone assessment\u003c\/li\u003e\n\u003cli\u003eDiagnosed or suspected Hashimoto's thyroiditis or autoimmune thyroid disease\u003c\/li\u003e\n\u003cli\u003eOn levothyroxine and wanting complete thyroid monitoring alongside cortisol\u003c\/li\u003e\n\u003cli\u003eNormal thyroid blood test results that do not match symptoms\u003c\/li\u003e\n\u003cli\u003eMen wanting a focused thyroid and cortisol assessment without a full sex hormone or cardiometabolic panel\u003c\/li\u003e\n\u003cli\u003eFamily history of thyroid disease or autoimmune conditions\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy This Test Is Particularly Important for Men\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eTSH alone misses cortisol-driven T3 suppression — the most commonly missed thyroid pattern in men under chronic occupational or psychological stress, producing full hypothyroid symptoms with a normal result\u003c\/li\u003e\n\u003cli\u003eBoth TPO and Tg antibodies are required for complete Hashimoto's screening — some men have elevated Tg antibodies with normal TPO, making both essential\u003c\/li\u003e\n\u003cli\u003eThe 4-point cortisol profile identifies which phase of the day is driving thyroid T3 suppression — morning, noon, evening, or night — and reveals night cortisol's role in worsening Hashimoto's autoimmunity\u003c\/li\u003e\n\u003cli\u003eCortisol-driven thyroid suppression impairs Leydig cell testosterone production, compounds fatigue, and worsens metabolic function — all with a normal TSH\u003c\/li\u003e\n\u003cli\u003eLow thyroid function raises cardiovascular risk and directly suppresses testosterone synthesis — patterns invisible to TSH-only testing\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\n\u003cp\u003eEmail us at \u003ca href=\"mailto:info@hormonelab.co.uk\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e with your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours.\u003c\/p\u003e\n\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered directly to your door\u003c\/li\u003e\n\u003cli\u003eCollect saliva at four time points (morning before 9am, noon, evening, night) and blood spot via finger-prick\u003c\/li\u003e\n\u003cli\u003ePost your samples to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your full report by email within 3–5 working days\u003c\/li\u003e\n\u003c\/ol\u003e\n\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll 10 marker results with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eVisual cortisol rhythm chart showing your full four-point daily curve\u003c\/li\u003e\n\u003cli\u003eVisual charts for the full thyroid panel including TPO and Tg antibodies\u003c\/li\u003e\n\u003cli\u003eIntegrated clinical interpretation of how cortisol rhythm and thyroid function interact by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003ePersonalised next-step recommendations\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePioneers of at-home \u003cstrong\u003edried blood spot (DBS)\u003c\/strong\u003e and saliva hormone testing\u003c\/li\u003e\n\u003cli\u003eAdvanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy\u003c\/li\u003e\n\u003cli\u003eQualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePersonalised reference ranges based on age and sex\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThrough our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to people across the UK and Europe — from the comfort of home.\u003c\/p\u003e\n\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhy test thyroid and cortisol together?\u003c\/strong\u003e\u003cbr\u003eCortisol suppresses T4-to-T3 conversion, producing hypothyroid symptoms with a normal TSH. Hashimoto's autoimmunity is directly worsened by cortisol dysregulation, particularly elevated night cortisol. Testing both together identifies whether symptoms stem from thyroid disease, cortisol-driven suppression, Hashimoto's, or a combination — each requiring a different approach.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes this test include sex hormones or cardiometabolic markers?\u003c\/strong\u003e\u003cbr\u003eNo. This profile focuses on thyroid function and the 4-point cortisol rhythm. For cardiometabolic markers alongside thyroid, see the Male CardioMetabolic \u0026amp; Thyroid Test Kit (SB-642). For sex hormones and SHBG, see the Male Comprehensive Hormone, Thyroid \u0026amp; CardioMetabolic Profile (SB-646M).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan I use this test if I am on TRT or levothyroxine?\u003c\/strong\u003e\u003cbr\u003eYes. This test helps men on TRT understand whether cortisol dysregulation or thyroid suppression is limiting therapy effectiveness. Levothyroxine dosing is most accurate when FT3, FT4, and antibodies are assessed alongside the cortisol that impairs T3 conversion.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is morning saliva collected before 9am?\u003c\/strong\u003e\u003cbr\u003eMorning cortisol must be collected before 9am, ideally within 30 minutes of waking, to accurately capture the Cortisol Awakening Response — the key diagnostic window for adrenal and thyroid activation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. There are no additional charges. 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By analysing key systems together, you can uncover the root causes of fatigue, stress, poor sleep, low testosterone symptoms, weight changes, low motivation, and metabolic or thyroid-related concerns.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eWhat’s Included in This Test\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eThe test kit includes a total of \u003cstrong\u003eover 100 tests\u003c\/strong\u003e, covering the following:\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e1. Blood Spot Hormone, Thyroid \u0026amp; CardioMetabolic Panel (LCMS \/ ICPMS – 27 Tests)\u003c\/strong\u003e\u003cbr\u003eThis test checks your key male hormones, thyroid function, heart health, inflammation, and essential minerals. Includes:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eCortisol (C)\u003c\/li\u003e\n\u003cli\u003eDHEA-S (DS)\u003c\/li\u003e\n\u003cli\u003eEstradiol (E2)\u003c\/li\u003e\n\u003cli\u003eEstriol (E3)\u003c\/li\u003e\n\u003cli\u003eEstrone (E1)\u003c\/li\u003e\n\u003cli\u003eFollicle Stimulating Hormone (FSH)\u003c\/li\u003e\n\u003cli\u003eFree Thyroxine (FT4)\u003c\/li\u003e\n\u003cli\u003eFree Triiodothyronine (FT3)\u003c\/li\u003e\n\u003cli\u003eHDL Cholesterol (HDL)\u003c\/li\u003e\n\u003cli\u003eHemoglobin A1c (HbA1c)\u003c\/li\u003e\n\u003cli\u003eHigh Sensitivity C-Reactive Protein (hs-CRP)\u003c\/li\u003e\n\u003cli\u003eInsulin (IN)\u003c\/li\u003e\n\u003cli\u003eLDL\u003c\/li\u003e\n\u003cli\u003eLuteinizing Hormone (LH)\u003c\/li\u003e\n\u003cli\u003eProgesterone (Pg)\u003c\/li\u003e\n\u003cli\u003eProstate-Specific Antigen (PSA)\u003c\/li\u003e\n\u003cli\u003eSex Hormone Binding Globulin (SHBG)\u003c\/li\u003e\n\u003cli\u003eTestosterone (T)\u003c\/li\u003e\n\u003cli\u003eThyroglobulin (Tgbn)\u003c\/li\u003e\n\u003cli\u003eThyroid Peroxidase Antibody (TPOab)\u003c\/li\u003e\n\u003cli\u003eThyroid Stimulating Hormone (TSH)\u003c\/li\u003e\n\u003cli\u003eTotal Cholesterol (CH)\u003c\/li\u003e\n\u003cli\u003eTotal Thyroxine (TT4)\u003c\/li\u003e\n\u003cli\u003eTriglycerides (TG)\u003c\/li\u003e\n\u003cli\u003eVLDL\u003c\/li\u003e\n\u003cli\u003eVitamin D2\u003c\/li\u003e\n\u003cli\u003eVitamin D3\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e2. Saliva Hormone Test – Daily Hormone \u0026amp; Stress Levels (LCMS – 10 Tests)\u003c\/strong\u003e\u003cbr\u003eMeasures your active hormones and daily cortisol rhythm to assess stress and energy patterns. Includes:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eEstradiol (E2)\u003c\/li\u003e\n\u003cli\u003eEstriol (E3)\u003c\/li\u003e\n\u003cli\u003eEstrone (E1)\u003c\/li\u003e\n\u003cli\u003eProgesterone (Pg)\u003c\/li\u003e\n\u003cli\u003eTestosterone (T)\u003c\/li\u003e\n\u003cli\u003eDHEA-S (DS)\u003c\/li\u003e\n\u003cli\u003eCortisol (C ×4 – taken at different times of the day)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e3. Advanced Neurotransmitter \u0026amp; Stress Profile (LCMS Dried Urine – 50 Tests)\u003c\/strong\u003e\u003cbr\u003eProvides deep insight into your brain chemistry, mood, focus, and sleep quality. Includes:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTryptophan (Trp)\u003c\/li\u003e\n\u003cli\u003eSerotonin (5-HT)\u003c\/li\u003e\n\u003cli\u003e5-HIAA\u003c\/li\u003e\n\u003cli\u003eGABA\u003c\/li\u003e\n\u003cli\u003eGlycine\u003c\/li\u003e\n\u003cli\u003eTaurine\u003c\/li\u003e\n\u003cli\u003eGlutamate\u003c\/li\u003e\n\u003cli\u003eGlutamine\u003c\/li\u003e\n\u003cli\u003eHistidine\u003c\/li\u003e\n\u003cli\u003eHistamine\u003c\/li\u003e\n\u003cli\u003eN-Methylhistamine\u003c\/li\u003e\n\u003cli\u003ePEA\u003c\/li\u003e\n\u003cli\u003eTyrosine\u003c\/li\u003e\n\u003cli\u003eTyramine\u003c\/li\u003e\n\u003cli\u003eDopamine\u003c\/li\u003e\n\u003cli\u003eDOPAC\u003c\/li\u003e\n\u003cli\u003eHVA\u003c\/li\u003e\n\u003cli\u003eNormetanephrine\u003c\/li\u003e\n\u003cli\u003eVMA\u003c\/li\u003e\n\u003cli\u003eKynurenine\u003c\/li\u003e\n\u003cli\u003eKynurenic Acid\u003c\/li\u003e\n\u003cli\u003e3-OH-Kynurenine\u003c\/li\u003e\n\u003cli\u003eXanthurenate\u003c\/li\u003e\n\u003cli\u003eCreatinine (Crtn ×5)\u003c\/li\u003e\n\u003cli\u003eFree Cortisol (FC ×4)\u003c\/li\u003e\n\u003cli\u003eFree Cortisone (FCn ×4)\u003c\/li\u003e\n\u003cli\u003eMelatonin (MT6s ×4)\u003c\/li\u003e\n\u003cli\u003eNorepinephrine (NE ×5)\u003c\/li\u003e\n\u003cli\u003eEpinephrine (Epi ×5)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e4. Heavy Metals \u0026amp; Essential Elements Test (ICPMS – 14 Tests)\u003c\/strong\u003e\u003cbr\u003eChecks for toxic metals and key minerals that may impact energy, metabolism, and overall health. Includes:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eIodine (I)\u003c\/li\u003e\n\u003cli\u003eBromine (Br)\u003c\/li\u003e\n\u003cli\u003eSelenium (Se)\u003c\/li\u003e\n\u003cli\u003eLithium (Li)\u003c\/li\u003e\n\u003cli\u003eArsenic (As)\u003c\/li\u003e\n\u003cli\u003eCadmium (Cd)\u003c\/li\u003e\n\u003cli\u003eMercury (Hg)\u003c\/li\u003e\n\u003cli\u003eCreatinine (Crtn)\u003c\/li\u003e\n\u003cli\u003eZinc (Zn)\u003c\/li\u003e\n\u003cli\u003eMagnesium (Mg)\u003c\/li\u003e\n\u003cli\u003eCopper (Cu)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eMen All-In-One Test: The Complete Guide to Hormones, Performance \u0026amp; Total Health\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eModern men often experience symptoms such as fatigue, low motivation, poor sleep, weight gain, brain fog, and reduced performance. These issues are frequently treated in isolation, yet they are usually connected. This test is designed to uncover the full picture by analysing hormones, brain chemistry, thyroid function, metabolism, and toxic exposure together.\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eHormones and Male Performance\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eBy analysing testosterone, DHEA-S, cortisol, estrogen markers, and binding proteins such as SHBG, this test helps you understand low testosterone symptoms and reduced libido, fatigue and lack of motivation, muscle loss and reduced strength, and hormonal imbalances affecting performance.\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eStress, Focus and Brain Chemistry\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eNeurotransmitters such as dopamine, serotonin, and GABA regulate mood, focus, motivation, and sleep. The advanced neurotransmitter profile provides deep insight into stress resilience and adrenal function, mental clarity and cognitive performance, mood stability and emotional balance, and sleep quality and recovery.\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eThyroid and Metabolic Health\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eBy measuring TSH, Free T3, Free T4, and thyroid antibodies, this test helps detect hidden imbalances that may contribute to fatigue, weight gain, and low energy. Cardiometabolic markers such as insulin, cholesterol, inflammation, and HbA1c also provide insight into metabolic health and long-term risk factors.\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eHidden Toxins and Nutrient Deficiencies\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eToxic elements such as mercury, arsenic, and cadmium may interfere with hormone production and brain health, while key nutrients like zinc, magnesium, and selenium are essential for testosterone production, energy metabolism, immune function, and cognitive performance.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch2\u003e\u003cstrong\u003eConvenient At-Home Testing with Lab Accuracy\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eUsing a combination of dried blood spot, saliva, and dried urine samples, you can complete the entire process from the comfort of your home. All samples are analysed using advanced laboratory technologies such as LC-MS and ICP-MS, ensuring a high level of precision and reliability.\u003c\/p\u003e\n\u003cp\u003eSimply collect your samples at home by following the instructions provided, then send them to our laboratory. Your results will be ready within \u003cstrong\u003e3–5 working days\u003c\/strong\u003e after the lab receives your samples. You will receive a detailed report with clear visuals and values, along with expert commentary from a \u003cstrong\u003eHormone \u0026amp; Neurotransmitter Specialist PhD Dr\u003c\/strong\u003e, including guidance on the next steps.\u003c\/p\u003e\n\u003cp\u003eThe test is suitable for both adults and children. \u003cstrong\u003eThe laboratory fee is included\u003c\/strong\u003e in the kit, so there are no additional lab costs or hidden charges. Customers are responsible for posting their samples to the laboratory, and \u003cstrong\u003ethe kit should be used within 12 months\u003c\/strong\u003e of purchase.\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eWhat This Test Helps You Achieve\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eUnderstand testosterone levels and overall hormone balance\u003c\/li\u003e\n\u003cli\u003eIdentify causes of fatigue, stress, and poor sleep\u003c\/li\u003e\n\u003cli\u003eEvaluate thyroid and metabolic function\u003c\/li\u003e\n\u003cli\u003eAnalyse stress response and adrenal rhythm\u003c\/li\u003e\n\u003cli\u003eAssess neurotransmitters linked to focus, mood, and performance\u003c\/li\u003e\n\u003cli\u003eDetect heavy metals and nutrient imbalances\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eWhy We Partner with ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAt Hormone Lab UK, every home test kit is analysed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e, a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic and research laboratory specialising in \u003cstrong\u003ehormone testing, thyroid testing, fertility testing, adrenal function, neurotransmitter analysis, cardiometabolic health, heavy metals, and wellness testing\u003c\/strong\u003e. Founded in 1998 by renowned biochemist and breast cancer researcher \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e, ZRT has become one of the world’s leading laboratories for advanced functional health testing.\u003c\/p\u003e\n\u003cp\u003eWith \u003cstrong\u003emore than 11 million laboratory tests\u003c\/strong\u003e performed and healthcare professionals in \u003cstrong\u003eover 96 countries\u003c\/strong\u003e relying on its expertise, ZRT is recognised for scientific excellence, analytical accuracy, and continuous innovation. The laboratory pioneered \u003cstrong\u003eat-home saliva hormone testing\u003c\/strong\u003e, introduced the \u003cstrong\u003efirst commercially available dried blood spot (DBS) hormone tests\u003c\/strong\u003e, and developed \u003cstrong\u003eDried Urine Testing (DUTS)\u003c\/strong\u003e, helping make advanced laboratory diagnostics more accessible and clinically meaningful.\u003c\/p\u003e\n\u003cp\u003eEvery sample is analysed using state-of-the-art \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e and \u003cstrong\u003eICP-MS\u003c\/strong\u003e technology under rigorous quality control standards, providing highly accurate, clinically reliable results. ZRT also collaborates with leading organisations, including the \u003cstrong\u003eCenters for Disease Control and Prevention (CDC)\u003c\/strong\u003e, the \u003cstrong\u003eNational Institutes of Health (NIH)\u003c\/strong\u003e, and major universities, supporting ongoing research and advances in laboratory medicine.\u003c\/p\u003e\n\u003cp\u003eBy partnering with ZRT Laboratory, Hormone Lab UK gives customers throughout the UK and Europe access to internationally trusted, research-backed laboratory testing that supports informed, personalised healthcare decisions.\u003c\/p\u003e","brand":"ZRT Laboratory","offers":[{"title":"Default Title","offer_id":57962656727421,"sku":"MEN-ALLIN-01","price":2099.3,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Men_s_All_in_One_Test.jpg?v=1785073912"},{"product_id":"male-comprehensive-hormone-profile-i-blood-spot","title":"Male Comprehensive Hormone Profile I | 8 Markers","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e B-242M | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Dried Blood Spot | \u003cstrong\u003eTest Method:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults:\u003c\/strong\u003e 3–5 Working Days | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eReport:\u003c\/strong\u003e Specialist Doctor Comment Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Men | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\u003ch2\u003eWhat This Test Measures\u003c\/h2\u003e\n\u003cp\u003eEight essential hormones from a single finger-prick dried blood spot using highly accurate \u003cstrong\u003eLC-MS\/MS technology\u003c\/strong\u003e:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eEstrone (E1)\u003c\/strong\u003e — an oestrogen that plays a role in male bone density and cardiovascular health; elevated levels can indicate aromatisation issues\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEstradiol (E2)\u003c\/strong\u003e — the primary oestrogen; elevated levels in men are linked to low libido, fat gain, and gynaecomastia\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEstriol (E3)\u003c\/strong\u003e — a weaker oestrogen that helps assess overall oestrogen balance in men\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProgesterone (Pg)\u003c\/strong\u003e — supports testosterone production and counteracts oestrogen dominance in men\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTestosterone (T)\u003c\/strong\u003e — the primary male sex hormone; critical for energy, muscle mass, libido, mood, and metabolic health\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDHEA-S (DS)\u003c\/strong\u003e — an adrenal hormone that declines with age; linked to vitality, immune function, and stress resilience\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCortisol (C)\u003c\/strong\u003e — the stress hormone; chronically elevated cortisol directly suppresses testosterone production\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSHBG (Sex Hormone Binding Globulin)\u003c\/strong\u003e — determines how much testosterone is biologically available; high SHBG can cause testosterone deficiency symptoms even when total testosterone appears normal\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eCould a Hormone Imbalance Be Behind Your Fatigue, Low Libido, or Mood Changes?\u003c\/h2\u003e\n\u003cp\u003eMale hormonal health is rarely a single-hormone issue — testosterone, cortisol, DHEA-S, oestrogens, and SHBG all interact in a complex system. When one is off, the whole system is affected. Symptoms are frequently dismissed as stress or ageing when the root cause may be hormonal. If you recognise any of the following, this comprehensive panel could reveal what’s really going on:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLow libido or sexual dysfunction\u003c\/li\u003e\n\u003cli\u003ePersistent fatigue and low energy despite adequate sleep\u003c\/li\u003e\n\u003cli\u003eLoss of muscle mass or increased body fat, especially around the abdomen\u003c\/li\u003e\n\u003cli\u003eMood swings, depression, irritability, or anxiety\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor concentration, or memory lapses\u003c\/li\u003e\n\u003cli\u003eSleep disturbances or insomnia\u003c\/li\u003e\n\u003cli\u003eHot flushes or night sweats (andropause symptoms)\u003c\/li\u003e\n\u003cli\u003eDecreased stamina or physical performance\u003c\/li\u003e\n\u003cli\u003eSlow metabolism or unexplained weight gain\u003c\/li\u003e\n\u003cli\u003eBurnout or chronic stress\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy a Comprehensive Panel Matters\u003c\/h2\u003e\n\u003cp\u003eA standard GP testosterone test only measures total testosterone — which can miss significant hormonal dysfunction. This panel gives you a complete picture of your hormonal ecosystem, including how stress hormones and oestrogen are affecting your testosterone availability. This enables far more informed conversations with your GP or specialist.\u003c\/p\u003e\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSymptoms of low testosterone or andropause — fatigue, low libido, muscle loss, mood changes\u003c\/li\u003e\n\u003cli\u003eChronic stress, burnout, or suspected adrenal dysfunction\u003c\/li\u003e\n\u003cli\u003eSigns of elevated estradiol — gynaecomastia, abdominal fat, water retention\u003c\/li\u003e\n\u003cli\u003eNormal standard blood tests but persistent hormonal symptoms\u003c\/li\u003e\n\u003cli\u003eMonitoring hormone levels during or after TRT or other hormone therapy\u003c\/li\u003e\n\u003cli\u003eWanting a proactive, data-driven baseline of overall male hormonal health\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\n\u003cp\u003eEmail us at\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"mailto:info@hormonelab.co.uk\" rel=\"nofollow\" class=\"text-link\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e\u003cspan\u003e \u003c\/span\u003ewith your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours.\u003c\/p\u003e\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered to your door\u003c\/li\u003e\n\u003cli\u003eCollect your sample at home — a simple finger-prick dried blood spot; no clinic or GP visit needed\u003c\/li\u003e\n\u003cli\u003ePost your sample to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your results by email within 3–5 working days of the lab receiving your sample\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll eight hormone levels displayed clearly in graphics and numbers with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eWritten interpretation by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003eGuidance on what your results mean and what to do next\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e. ZRT is qualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e for testosterone and estradiol.\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhen is the best time to collect my sample?\u003c\/strong\u003e\u003cbr\u003eTestosterone follows a diurnal rhythm, peaking in the morning. Collect your sample between 7am and 9am for the most clinically meaningful result. Detailed timing guidance is included with your kit.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow does cortisol suppress testosterone?\u003c\/strong\u003e\u003cbr\u003eCortisol and testosterone share a common precursor — pregnenolone. Under chronic stress, the body prioritises cortisol production via pregnenolone steal, directly reducing the raw material available for testosterone synthesis. Elevated cortisol also suppresses LH signalling to the testes. This panel measures both, making the relationship visible.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat does DHEA-S tell me about my hormonal health?\u003c\/strong\u003e\u003cbr\u003eDHEA-S is the most abundant adrenal hormone in men and a key precursor to both testosterone and oestrogen. Its decline — which begins in the late 20s — directly reduces hormonal reserve and stress resilience. Low DHEA-S combined with high cortisol is a hallmark of adrenal burnout.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. You are only responsible for posting your sample to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":58590059987325,"sku":"501","price":219.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Insulin_Test_Kit.png?v=1787500073"},{"product_id":"male-elite-hormone-test-blood-spot","title":"Male Elite Hormone Test | E2, Pg, T \u0026 SHBG","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e B-240M | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Dried Blood Spot | \u003cstrong\u003eTest Method:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults:\u003c\/strong\u003e 3–5 Working Days | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eReport:\u003c\/strong\u003e Specialist Doctor Comment Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Men | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\u003ch2\u003eWhat This Test Measures\u003c\/h2\u003e\n\u003cp\u003eFour core sex hormone markers using highly accurate \u003cstrong\u003eLC-MS\/MS technology\u003c\/strong\u003e:\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTestosterone (T)\u003c\/strong\u003e — the primary male sex hormone; critical for energy, muscle mass, libido, mood, and metabolic health\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEstradiol (E2)\u003c\/strong\u003e — men produce estradiol too; elevated E2 is linked to low libido, fat gain, and mood issues\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProgesterone (Pg)\u003c\/strong\u003e — supports testosterone production and counteracts estrogen dominance in men\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSHBG (Sex Hormone Binding Globulin)\u003c\/strong\u003e — determines how much testosterone is biologically available; high SHBG can cause low-testosterone symptoms even when total testosterone appears normal\u003c\/p\u003e\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSymptoms of low testosterone — fatigue, low libido, muscle loss, brain fog\u003c\/li\u003e\n\u003cli\u003eSuspected andropause or age-related hormonal decline\u003c\/li\u003e\n\u003cli\u003eSigns of elevated estradiol — gynaecomastia, abdominal fat, water retention\u003c\/li\u003e\n\u003cli\u003eNormal standard blood tests but persistent hormonal symptoms\u003c\/li\u003e\n\u003cli\u003eMonitoring hormone levels during or after TRT or other hormone therapy\u003c\/li\u003e\n\u003cli\u003eUnderstanding why free testosterone availability may be reduced despite normal total testosterone\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eCould Low Testosterone or Estrogen Imbalance Be Affecting Your Health?\u003c\/h2\u003e\n\u003cp\u003eTestosterone, estradiol, and progesterone don’t operate in isolation in men — they interact constantly, and an imbalance in one affects the others. Symptoms are frequently dismissed as stress or ageing when the root cause may be hormonal. If you recognise any of the following, this panel could reveal what’s really going on:\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSymptoms of low testosterone:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLow libido or erectile dysfunction\u003c\/li\u003e\n\u003cli\u003ePersistent fatigue and low stamina\u003c\/li\u003e\n\u003cli\u003eLoss of muscle mass or increased body fat\u003c\/li\u003e\n\u003cli\u003eAnxiety, depression, or low mood\u003c\/li\u003e\n\u003cli\u003eBrain fog or forgetfulness\u003c\/li\u003e\n\u003cli\u003eDry skin or reduced body hair\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSymptoms of elevated estradiol (E2) in men:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eGynaecomastia (breast tissue growth)\u003c\/li\u003e\n\u003cli\u003eIncreased abdominal fat\u003c\/li\u003e\n\u003cli\u003eWater retention or bloating\u003c\/li\u003e\n\u003cli\u003eMood swings or irritability\u003c\/li\u003e\n\u003cli\u003eDecreased fertility\u003c\/li\u003e\n\u003cli\u003ePoor concentration or memory lapses\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSymptoms of progesterone imbalance in men:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLow testosterone (progesterone is a precursor)\u003c\/li\u003e\n\u003cli\u003eIncreased estrogen dominance\u003c\/li\u003e\n\u003cli\u003eMood disturbances, anxiety, or sleep issues\u003c\/li\u003e\n\u003cli\u003eDecreased libido\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSymptoms of SHBG imbalance:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHigh SHBG: fatigue, low libido, muscle loss, and depression — even when total testosterone appears normal\u003c\/li\u003e\n\u003cli\u003eLow SHBG: acne, hair loss, and increased estrogen conversion\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered to your door\u003c\/li\u003e\n\u003cli\u003eCollect your sample at home — a simple finger-prick dried blood spot; no clinic or GP visit needed\u003c\/li\u003e\n\u003cli\u003ePost your sample to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your results by email within 3–5 working days of the lab receiving your sample\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll four hormone levels displayed clearly in graphics and numbers with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eWritten interpretation by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003eGuidance on what your results mean and what to do next\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e. ZRT is qualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e for testosterone and estradiol, delivering clinical-grade accuracy from a home-collected dried blood spot.\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhen is the best time to collect my sample?\u003c\/strong\u003e\u003cbr\u003eTestosterone follows a diurnal rhythm, peaking in the morning. Collect your sample between 7am and 9am for the most clinically meaningful result. Detailed timing guidance is included with your kit.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy does estradiol matter for men?\u003c\/strong\u003e\u003cbr\u003eMen convert a small amount of testosterone into estradiol via aromatase. Elevated estradiol — from excess body fat, alcohol, or aromatase overactivity — suppresses testosterone production via negative feedback, drives fat storage, and is associated with gynaecomastia and mood disturbances. Monitoring E2 alongside testosterone is essential for a complete picture.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. You are only responsible for posting your sample to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":58590092034429,"sku":"344","price":199.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Insulin_Test_Kit.png?v=1787500073"},{"product_id":"male-comprehensive-hormone-profile-ii-blood-spot","title":"Male Comprehensive Hormone Profile II | 14 Markers","description":"\u003cp\u003e\u003cstrong\u003eTest ID:\u003c\/strong\u003e B-243M | \u003cstrong\u003eSample Type:\u003c\/strong\u003e Dried Blood Spot | \u003cstrong\u003eTest Method:\u003c\/strong\u003e LC-MS\/MS | \u003cstrong\u003eResults:\u003c\/strong\u003e 3–5 Working Days | \u003cstrong\u003eLaboratory:\u003c\/strong\u003e ZRT Laboratory – CLIA Certified | \u003cstrong\u003eReport:\u003c\/strong\u003e Specialist Doctor Comment Included | \u003cstrong\u003eSuitable For:\u003c\/strong\u003e Men | \u003cstrong\u003eCollect Sample At Home:\u003c\/strong\u003e No Clinic Visit Required\u003c\/p\u003e\n\u003ch2\u003eWhat This Test Measures\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSex Hormones \u0026amp; Adrenal Markers (8):\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eEstrone (E1)\u003c\/strong\u003e — an oestrogen present in men; elevated levels are linked to fat gain and hormonal imbalance\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEstradiol (E2)\u003c\/strong\u003e — the primary oestrogen; men need balanced E2 for bone density and cardiovascular health, but excess causes low libido and gynaecomastia\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEstriol (E3)\u003c\/strong\u003e — a weaker oestrogen that helps assess overall oestrogen load in men\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProgesterone (Pg)\u003c\/strong\u003e — supports testosterone production and counteracts oestrogen dominance in men\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTestosterone (T)\u003c\/strong\u003e — the primary male sex hormone; critical for energy, muscle mass, libido, mood, and metabolic health\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDHEA-S (DS)\u003c\/strong\u003e — an adrenal precursor hormone that declines with age; linked to vitality, immune function, and testosterone production\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCortisol (C)\u003c\/strong\u003e — the stress hormone; chronically elevated cortisol directly suppresses testosterone production\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSHBG\u003c\/strong\u003e — regulates how much testosterone is biologically available; high SHBG causes low-T symptoms even when total testosterone appears normal\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFull Thyroid Panel (6):\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTSH\u003c\/strong\u003e — the primary screening marker for thyroid function\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFree T3 (fT3)\u003c\/strong\u003e — the active thyroid hormone; low fT3 is linked to fatigue, weight gain, and depression\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFree T4 (fT4)\u003c\/strong\u003e — the storage thyroid hormone converted to T3; key for assessing conversion issues\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTotal T4 (TT4)\u003c\/strong\u003e — measures total thyroxine including protein-bound hormone\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTPO Antibodies (TPOab)\u003c\/strong\u003e — elevated levels indicate autoimmune thyroid disease (Hashimoto’s thyroiditis)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThyroglobulin (Tgbn)\u003c\/strong\u003e — a marker for thyroid tissue health and iodine-related dysfunction\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWho Should Consider This Test?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eComplex or overlapping symptoms involving both hormones and thyroid\u003c\/li\u003e\n\u003cli\u003eSymptoms persisting despite normal standard GP blood tests\u003c\/li\u003e\n\u003cli\u003eFamily history of thyroid disease or autoimmune conditions\u003c\/li\u003e\n\u003cli\u003eSuspected andropause, adrenal fatigue, or oestrogen dominance\u003c\/li\u003e\n\u003cli\u003eMonitoring multiple hormone systems during or after TRT, thyroid medication, or other treatment\u003c\/li\u003e\n\u003cli\u003eWanting the most comprehensive male hormone and thyroid baseline available at home\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eNot Sure Which Test Is Right for You?\u003c\/h2\u003e\n\u003cp\u003eEmail us at\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"mailto:info@hormonelab.co.uk\" rel=\"nofollow\" class=\"text-link\"\u003einfo@hormonelab.co.uk\u003c\/a\u003e\u003cspan\u003e \u003c\/span\u003ewith your gender, age, symptoms, medications, and any current treatments. We will forward your enquiry to our doctors and respond within 24 hours.\u003c\/p\u003e\n\u003ch2\u003eAre Complex, Overlapping Symptoms Leaving You Without Answers?\u003c\/h2\u003e\n\u003cp\u003eThyroid and sex hormones are deeply interconnected in men — thyroid dysfunction can suppress testosterone, raise SHBG, and worsen andropause symptoms. Many men are treated for low testosterone when the root cause is actually thyroid dysfunction. If you recognise any of the following, this comprehensive 14-marker panel could finally give you the full picture:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePersistent fatigue or exhaustion that doesn’t improve with rest\u003c\/li\u003e\n\u003cli\u003eLow libido or erectile dysfunction\u003c\/li\u003e\n\u003cli\u003eLoss of muscle mass or increased body fat\u003c\/li\u003e\n\u003cli\u003eMood swings, depression, or anxiety\u003c\/li\u003e\n\u003cli\u003eBrain fog, poor concentration, or increased forgetfulness\u003c\/li\u003e\n\u003cli\u003eSleep disturbances or insomnia\u003c\/li\u003e\n\u003cli\u003eHot flushes or night sweats (andropause symptoms)\u003c\/li\u003e\n\u003cli\u003eUnexplained weight gain or slow metabolism\u003c\/li\u003e\n\u003cli\u003eHair thinning or loss\u003c\/li\u003e\n\u003cli\u003eCold intolerance or low body temperature\u003c\/li\u003e\n\u003cli\u003eHigh cholesterol, elevated triglycerides, or heart palpitations\u003c\/li\u003e\n\u003cli\u003eFertility concerns\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy Test Hormones and Thyroid Together?\u003c\/h2\u003e\n\u003cp\u003eA standard GP test typically only checks total testosterone and TSH separately — missing the complex interplay between these systems. This panel measures \u003cstrong\u003e14 markers\u003c\/strong\u003e across sex hormones, adrenal function, and a full thyroid panel, giving you and your doctor a complete clinical picture and avoiding misdiagnosis.\u003c\/p\u003e\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit — delivered to your door\u003c\/li\u003e\n\u003cli\u003eCollect your sample at home — a simple finger-prick dried blood spot; no clinic or GP visit needed\u003c\/li\u003e\n\u003cli\u003ePost your sample to ZRT Laboratory using the return instructions provided\u003c\/li\u003e\n\u003cli\u003eReceive your results by email within 3–5 working days of the lab receiving your sample\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003eWhat You Receive\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAll 14 markers displayed clearly in graphics and numbers with male-specific reference ranges\u003c\/li\u003e\n\u003cli\u003eWritten interpretation by a Hormone Specialist PhD Doctor\u003c\/li\u003e\n\u003cli\u003eGuidance on what your results mean and what to do next\u003c\/li\u003e\n\u003cli\u003eLaboratory fee included — no hidden charges\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy We Use ZRT Laboratory\u003c\/h2\u003e\n\u003cp\u003eAll testing is performed by \u003cstrong\u003eZRT Laboratory\u003c\/strong\u003e — a globally recognised, \u003cstrong\u003eCLIA-certified\u003c\/strong\u003e diagnostic laboratory founded in 1998 by \u003cstrong\u003eDr. David Zava, PhD\u003c\/strong\u003e. ZRT has performed \u003cstrong\u003eover 11 million tests\u003c\/strong\u003e and is trusted by healthcare professionals in \u003cstrong\u003e96+ countries\u003c\/strong\u003e. ZRT is qualified for the \u003cstrong\u003eCDC Hormone Standardization (HoSt) Program\u003c\/strong\u003e for testosterone and estradiol, and uses advanced \u003cstrong\u003eLC-MS\/MS\u003c\/strong\u003e technology for clinical-grade accuracy.\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is the difference between Profile I and Profile II?\u003c\/strong\u003e\u003cbr\u003eProfile I measures 8 sex hormones and adrenal markers. Profile II includes all 8 of those markers plus a full 6-marker thyroid panel — TSH, Free T3, Free T4, Total T4, TPO Antibodies, and Thyroglobulin — giving 14 markers in total. Profile II is recommended if you have any thyroid symptoms, a family history of thyroid disease, or suspect both systems may be involved.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan thyroid dysfunction cause low testosterone symptoms?\u003c\/strong\u003e\u003cbr\u003eYes — significantly so. Hypothyroidism raises SHBG, which reduces free testosterone availability. It also impairs testicular testosterone production and reduces LH sensitivity. Men with symptoms of low testosterone who have normal total testosterone levels should always have thyroid function assessed alongside SHBG.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat does a high TPO antibody result mean?\u003c\/strong\u003e\u003cbr\u003eElevated TPO antibodies indicate that your immune system is attacking your thyroid gland — the hallmark of Hashimoto’s thyroiditis. Many men with Hashimoto’s have normal TSH levels for years before diagnosis. This panel measures TPOab so that autoimmune thyroid disease can be identified early.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the price include the laboratory fee?\u003c\/strong\u003e\u003cbr\u003eYes. The full laboratory analysis fee is included. You are only responsible for posting your sample to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long is the kit valid for?\u003c\/strong\u003e\u003cbr\u003eThe kit must be used within \u003cstrong\u003e12 months\u003c\/strong\u003e of the purchase date.\u003c\/p\u003e","brand":"Hormone Lab UK","offers":[{"title":"Default Title","offer_id":58590121132413,"sku":"751","price":249.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/files\/Insulin_Test_Kit.png?v=1787500073"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1885\/4859\/collections\/purple_Colour_dc5a7ae8-9455-4b89-89ff-f95cce78c184-2969984.jpg?v=1772194300","url":"https:\/\/hormonelab.co.uk\/collections\/male-profile-tests.oembed?page=3","provider":"Hormone Lab UK","version":"1.0","type":"link"}